Click here to switch to the map view.

The map label for this gene is recQ [H]

Identifier: 116688366

GI number: 116688366

Start: 398447

End: 400294

Strand: Direct

Name: recQ [H]

Synonym: Bcen2424_0342

Alternate gene names: 116688366

Gene position: 398447-400294 (Clockwise)

Preceding gene: 116688365

Following gene: 116688367

Centisome position: 11.44

GC content: 67.64

Gene sequence:

>1848_bases
ATGTCCCGCGCCCTCGAAATACTCGACGAAGTCTTTGGTTATTCCGCCTTTCGCGGCCAGCAGGGCGAGATCGTCGAGCA
CGTCGCCGGCGGCGGCGATTGTCTCGTGCTGATGCCGACCGGCGGCGGCAAGTCGCTGTGCTACCAGATTCCCGCGCTGC
TGCGCCGAGAGGCCGGGCAGGGCGCCGGCATCGTCGTGTCGCCGCTGATCGCGCTGATGCAGGACCAGGTCGCCGCGTTG
AGCGAAGTCGGCGTGCGCGCGGCCTACCTGAATTCGACGCTGTCGGGCGCCGAGGCCGCGGCCACCGAGCGCGCGCTGCG
CGAAGGCGAAATCGACCTGCTGTACGTCGCGCCGGAGCGCTTGATGACGGGGCGCTTCCTCGAGCTGCTCGAGCGCGCGA
AGATCGGCCTGTTCGCGATCGACGAAGCGCACTGCGTGTCGCAATGGGGGCACGATTTCCGCCCGGAATACATCCAGCTG
TCGGTGTTGCACGAGCGCTTCCCGTCGGTGCCGCGCATCGCGCTGACCGCCACGGCCGACGCGATCACGCGCGACGAGAT
CATCCATCGTCTCGCGCTCGACGACGCGCGCGTGTTCGTGTCGAGCTTCGACCGCCCCAACATCCGTTACCGGATCGTCG
AAAAGGACAACGCGCGCTCGCAGTTGCTCGATTTCATCCGTGCCGAGCACACGAATGCCGACGGCACGACGGACGCGGGC
GTCGTCTATTGCCTGTCGCGTCGCAAGGTCGAGGAAACGGCCGAATGGCTGAAGGCGCAGGGCGTGCGCGCGCTGCCGTA
TCACGCGGGGATGGAGTTCGAGGTGCGGCAGAAGCACCAGGAAATGTTCCAGCGCGAGGAAGGCATCGTGATGTGCGCGA
CGATCGCGTTCGGCATGGGTATCGACAAGCCCGACGTGCGCTTCGTCGCGCACCTCGATTTACCGAAGAGCGTCGAAGGC
TATTACCAGGAAACCGGCCGCGCGGGTCGTGACGGGATGCCCGCCAACGCGTGGATGGCGTATGGCCTCGGCGATGTCGT
CCAGCAGCGCAAGATGATCGACGAATCCGATGCGGACGACGCGCACAAGCGCGTGCAGACGTCGAAGCTCGACGCGCTGC
TCGGGTTGTGCGAAACGATCTCGTGCCGCCGCGTGCGGCTGCTGAATTACTTCGGCGAGGCGAGCCAGCCGTGCGGCAAC
TGCGACACGTGCCTCGAGCCGCCCGCTTCGTGGGATGCGACGCGTGAGGCGCAGATGGCGCTGTCGTGCGTGTTCCGCGC
ACAGCGCGCGAGCGGCTTCAATTTCGGCTCGAGCCACCTGATCGAGATCCTGCGCGGCGGGCGCACCGAGAAGGTTTTGC
AGCGCGGCCACGACCAGCTCAGCACGTTCGGCATCGGCGCGGCGCTGTCCGAGCCCGAGTGGCGCGCGATTTTCCGGCAA
CTGGTCGCGTACGGCTACCTGGCGGTCGACCATGGCGGCTTCGGCGCGCTGATGCTGACCGAGGCCGCGAAGCCCGTGCT
GAAGAACGAGGAAAAGGTCACGTTGCGCCGCTACGTGAAGCCGCAGCGCACCCGCCAGTCGTCGAGCCGCAGCGGCACGC
GCGTCGACCCGACGGCCGGCATGGGCGCCCGCGAGCGCGCGCGGTGGGACGCGCTGCGCGCATGGCGCGCGGAAACCGCG
AAGACGGACGGCGTGCCGGCCTACGTGATCTTCCACGACGCGACGCTCGCCGAAATCGCGCGCAACGCGCCGGAGACGAT
CGACGACCTGCGTCACATCCCCGGCATGGGCGTGCGCAAGCTGGAACGCTTCGGTGACGAGATCATCGACGTCGTCGAAT
CGGCCTGA

Upstream 100 bases:

>100_bases
CGAACCCTGACCGAACGGCCAACGTCGCGCGATTCGCCACGCGTCGCGCGAGCGGGTTGTTAAAATTGCGTTCATCGCTT
AGCCGTCCCTGTTCCTATTC

Downstream 100 bases:

>100_bases
CACAGCGTTCCGACCCCTCCTGTAAACCCCGCGATCGGCCGGCAAATCACGCAAGCCGTTGACTTAGTTGGTATTTCCGG
AATATCATGCTGGGTTCCGG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MSRALEILDEVFGYSAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPALLRREAGQGAGIVVSPLIALMQDQVAAL
SEVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPERLMTGRFLELLERAKIGLFAIDEAHCVSQWGHDFRPEYIQL
SVLHERFPSVPRIALTATADAITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAG
VVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEVRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEG
YYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADDAHKRVQTSKLDALLGLCETISCRRVRLLNYFGEASQPCGN
CDTCLEPPASWDATREAQMALSCVFRAQRASGFNFGSSHLIEILRGGRTEKVLQRGHDQLSTFGIGAALSEPEWRAIFRQ
LVAYGYLAVDHGGFGALMLTEAAKPVLKNEEKVTLRRYVKPQRTRQSSSRSGTRVDPTAGMGARERARWDALRAWRAETA
KTDGVPAYVIFHDATLAEIARNAPETIDDLRHIPGMGVRKLERFGDEIIDVVESA

Sequences:

>Translated_615_residues
MSRALEILDEVFGYSAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPALLRREAGQGAGIVVSPLIALMQDQVAAL
SEVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPERLMTGRFLELLERAKIGLFAIDEAHCVSQWGHDFRPEYIQL
SVLHERFPSVPRIALTATADAITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAG
VVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEVRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEG
YYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADDAHKRVQTSKLDALLGLCETISCRRVRLLNYFGEASQPCGN
CDTCLEPPASWDATREAQMALSCVFRAQRASGFNFGSSHLIEILRGGRTEKVLQRGHDQLSTFGIGAALSEPEWRAIFRQ
LVAYGYLAVDHGGFGALMLTEAAKPVLKNEEKVTLRRYVKPQRTRQSSSRSGTRVDPTAGMGARERARWDALRAWRAETA
KTDGVPAYVIFHDATLAEIARNAPETIDDLRHIPGMGVRKLERFGDEIIDVVESA
>Mature_614_residues
SRALEILDEVFGYSAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPALLRREAGQGAGIVVSPLIALMQDQVAALS
EVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPERLMTGRFLELLERAKIGLFAIDEAHCVSQWGHDFRPEYIQLS
VLHERFPSVPRIALTATADAITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAGV
VYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEVRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEGY
YQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADDAHKRVQTSKLDALLGLCETISCRRVRLLNYFGEASQPCGNC
DTCLEPPASWDATREAQMALSCVFRAQRASGFNFGSSHLIEILRGGRTEKVLQRGHDQLSTFGIGAALSEPEWRAIFRQL
VAYGYLAVDHGGFGALMLTEAAKPVLKNEEKVTLRRYVKPQRTRQSSSRSGTRVDPTAGMGARERARWDALRAWRAETAK
TDGVPAYVIFHDATLAEIARNAPETIDDLRHIPGMGVRKLERFGDEIIDVVESA

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=654, Percent_Identity=34.7094801223242, Blast_Score=360, Evalue=2e-99,
Organism=Homo sapiens, GI14591902, Length=420, Percent_Identity=37.8571428571429, Blast_Score=286, Evalue=4e-77,
Organism=Homo sapiens, GI14591904, Length=420, Percent_Identity=37.8571428571429, Blast_Score=286, Evalue=4e-77,
Organism=Homo sapiens, GI148612816, Length=474, Percent_Identity=37.7637130801688, Blast_Score=276, Evalue=4e-74,
Organism=Homo sapiens, GI51242947, Length=401, Percent_Identity=39.1521197007481, Blast_Score=256, Evalue=5e-68,
Organism=Homo sapiens, GI51242943, Length=401, Percent_Identity=39.1521197007481, Blast_Score=256, Evalue=6e-68,
Organism=Homo sapiens, GI169218196, Length=565, Percent_Identity=31.6814159292035, Blast_Score=249, Evalue=7e-66,
Organism=Homo sapiens, GI110735439, Length=505, Percent_Identity=33.4653465346535, Blast_Score=249, Evalue=7e-66,
Organism=Homo sapiens, GI284005309, Length=347, Percent_Identity=35.7348703170029, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI148613856, Length=346, Percent_Identity=24.8554913294798, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI38201710, Length=346, Percent_Identity=24.8554913294798, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI48994977, Length=618, Percent_Identity=45.1456310679612, Blast_Score=534, Evalue=1e-153,
Organism=Escherichia coli, GI87082221, Length=346, Percent_Identity=24.8554913294798, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=514, Percent_Identity=39.1050583657588, Blast_Score=333, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI71987997, Length=412, Percent_Identity=40.2912621359223, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI71987993, Length=412, Percent_Identity=40.2912621359223, Blast_Score=298, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI32564293, Length=672, Percent_Identity=31.6964285714286, Blast_Score=292, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI17552866, Length=496, Percent_Identity=35.0806451612903, Blast_Score=252, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI71995718, Length=352, Percent_Identity=24.4318181818182, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17510307, Length=322, Percent_Identity=23.9130434782609, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17510309, Length=322, Percent_Identity=23.9130434782609, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71987143, Length=337, Percent_Identity=25.5192878338279, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71995514, Length=220, Percent_Identity=25.9090909090909, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115533224, Length=350, Percent_Identity=22.5714285714286, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=542, Percent_Identity=35.239852398524, Blast_Score=344, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6324778, Length=338, Percent_Identity=25.1479289940828, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6325138, Length=235, Percent_Identity=28.936170212766, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646066, Length=508, Percent_Identity=39.9606299212598, Blast_Score=354, Evalue=1e-97,
Organism=Drosophila melanogaster, GI24664226, Length=441, Percent_Identity=37.6417233560091, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI62472181, Length=431, Percent_Identity=38.0510440835267, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24664230, Length=431, Percent_Identity=37.8190255220418, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI21358123, Length=355, Percent_Identity=35.2112676056338, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI28574962, Length=352, Percent_Identity=23.8636363636364, Blast_Score=66, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 68100; Mature: 67969

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRALEILDEVFGYSAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPALLRREAGQ
CCHHHHHHHHHHCCHHCCCCCCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
GAGIVVSPLIALMQDQVAALSEVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECHHH
LMTGRFLELLERAKIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPSVPRIALTATAD
HHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECHH
AITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCH
VVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEVRQKHQEMFQREEGIVMCATIAFGMG
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCC
IDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADD
CCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCCCHH
AHKRVQTSKLDALLGLCETISCRRVRLLNYFGEASQPCGNCDTCLEPPASWDATREAQMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LSCVFRAQRASGFNFGSSHLIEILRGGRTEKVLQRGHDQLSTFGIGAALSEPEWRAIFRQ
HHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHH
LVAYGYLAVDHGGFGALMLTEAAKPVLKNEEKVTLRRYVKPQRTRQSSSRSGTRVDPTAG
HHHHCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCCC
MGARERARWDALRAWRAETAKTDGVPAYVIFHDATLAEIARNAPETIDDLRHIPGMGVRK
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHCCCHHHHHHHHHCCCCCHHH
LERFGDEIIDVVESA
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRALEILDEVFGYSAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPALLRREAGQ
CHHHHHHHHHHCCHHCCCCCCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
GAGIVVSPLIALMQDQVAALSEVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECHHH
LMTGRFLELLERAKIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPSVPRIALTATAD
HHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECHH
AITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARSQLLDFIRAEHTNADGTTDAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCH
VVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEVRQKHQEMFQREEGIVMCATIAFGMG
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCC
IDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADD
CCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCCCHH
AHKRVQTSKLDALLGLCETISCRRVRLLNYFGEASQPCGNCDTCLEPPASWDATREAQMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LSCVFRAQRASGFNFGSSHLIEILRGGRTEKVLQRGHDQLSTFGIGAALSEPEWRAIFRQ
HHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHH
LVAYGYLAVDHGGFGALMLTEAAKPVLKNEEKVTLRRYVKPQRTRQSSSRSGTRVDPTAG
HHHHCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCCC
MGARERARWDALRAWRAETAKTDGVPAYVIFHDATLAEIARNAPETIDDLRHIPGMGVRK
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHCCCHHHHHHHHHCCCCCHHH
LERFGDEIIDVVESA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]