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The map label for this gene is gmhA [H]

Identifier: 116688315

GI number: 116688315

Start: 332785

End: 333369

Strand: Direct

Name: gmhA [H]

Synonym: Bcen2424_0291

Alternate gene names: 116688315

Gene position: 332785-333369 (Clockwise)

Preceding gene: 116688314

Following gene: 116688316

Centisome position: 9.55

GC content: 70.43

Gene sequence:

>585_bases
ATGTCAGTCGAACGTATTCAGCAACAATTCCGCGACAGCGCCGCGCTTCACGCCGAAGCGGCCGACGCGCTGTCGCTGCC
GATCGCAGCCGCGGTCGATGCGATGTTCGCCGCGCTGGCGAACGGCAACAAGATCGTCGCGTGCGGTGACGGCCCGTCGG
CCGCCGCTGCGCAGTACCTCGCCGCGTCGCTCGTCGGCGGTTTCGAGCGCGAACGTCCGGGCCTGCCCGCGATCGCGCTG
GCCACCGACGCGTCGCAGGCCGGCCTCGCGGGCGCGGCGGCGGCCGAGCAGTTGTTCGCGCAGCAGGTGCGCGTGCTGGG
CCAGACGGGCGACATCCTGCTGGTGCTCGACGCAGGCGGCGCATCGCCGCGCGTGCTCGCGGCGATCGACGAGGCGCACG
AGCGCGAGATGACCGTCATCGCATTGACGGGCGGCAACGACCACACGGTCGCGGCCGCGCTGTCCGACACCGATATTCCA
ATCAGCGTGCCCGCCGTTCGCGCGGCGCGCATCCACGAAGTCCATCTGCTGACCATCCACAGCCTGTGCGACGGCATCGA
CGCGATGCTGCTGGGTGAGGATTGA

Upstream 100 bases:

>100_bases
GACCCCCGGAGAGGGCGCCGGAGTACGGTAAACTCGCCGCACCCACGATGTCGCGCGAGTTGTGCCACGTTGTGCCACGC
GCCCAGTTCACCAGGAATCG

Downstream 100 bases:

>100_bases
ACGAAGGAGAGCCGTCGATGAATCAAAGCCGCGTCAAACAGACGCTCGTCAGGACCACGCTGCTCGCCGCGCTGACGGCG
GGCCTCGCCGTGTCGCTGCA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MSVERIQQQFRDSAALHAEAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAQYLAASLVGGFERERPGLPAIAL
ATDASQAGLAGAAAAEQLFAQQVRVLGQTGDILLVLDAGGASPRVLAAIDEAHEREMTVIALTGGNDHTVAAALSDTDIP
ISVPAVRAARIHEVHLLTIHSLCDGIDAMLLGED

Sequences:

>Translated_194_residues
MSVERIQQQFRDSAALHAEAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAQYLAASLVGGFERERPGLPAIAL
ATDASQAGLAGAAAAEQLFAQQVRVLGQTGDILLVLDAGGASPRVLAAIDEAHEREMTVIALTGGNDHTVAAALSDTDIP
ISVPAVRAARIHEVHLLTIHSLCDGIDAMLLGED
>Mature_193_residues
SVERIQQQFRDSAALHAEAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAQYLAASLVGGFERERPGLPAIALA
TDASQAGLAGAAAAEQLFAQQVRVLGQTGDILLVLDAGGASPRVLAAIDEAHEREMTVIALTGGNDHTVAAALSDTDIPI
SVPAVRAARIHEVHLLTIHSLCDGIDAMLLGED

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=189, Percent_Identity=43.3862433862434, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1786416, Length=151, Percent_Identity=34.4370860927152, Blast_Score=88, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 19690; Mature: 19559

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVERIQQQFRDSAALHAEAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAQYL
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
AASLVGGFERERPGLPAIALATDASQAGLAGAAAAEQLFAQQVRVLGQTGDILLVLDAGG
HHHHHCCHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
ASPRVLAAIDEAHEREMTVIALTGGNDHTVAAALSDTDIPISVPAVRAARIHEVHLLTIH
CCCEEEEEEHHHCCCCEEEEEEECCCCCEEEEEECCCCCCEECCCHHHHHHHEEHEEEHH
SLCDGIDAMLLGED
HHHCCCCEEEECCC
>Mature Secondary Structure 
SVERIQQQFRDSAALHAEAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAQYL
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
AASLVGGFERERPGLPAIALATDASQAGLAGAAAAEQLFAQQVRVLGQTGDILLVLDAGG
HHHHHCCHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
ASPRVLAAIDEAHEREMTVIALTGGNDHTVAAALSDTDIPISVPAVRAARIHEVHLLTIH
CCCEEEEEEHHHCCCCEEEEEEECCCCCEEEEEECCCCCCEECCCHHHHHHHEEHEEEHH
SLCDGIDAMLLGED
HHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA