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The map label for this gene is gcvT [H]

Identifier: 116626954

GI number: 116626954

Start: 9941834

End: 9942703

Strand: Direct

Name: gcvT [H]

Synonym: Acid_7931

Alternate gene names: 116626954

Gene position: 9941834-9942703 (Clockwise)

Preceding gene: 116626953

Following gene: 116626958

Centisome position: 99.76

GC content: 62.87

Gene sequence:

>870_bases
ATGACTCAGGGTTACGAAGCGTTGCGCCGCGGCGCCGCGTGGATCGATCTTTCCAAGCGCGGCCGGATCGCAGTCCGCGG
CCGCGATCGCGCCCGCCTGCTGCACGCCATCACCAGTAATGAAGTCAAAAAGATGACACCGGGAAGCGGCTGTTACGCAT
TCCTGCTCAGTCCGCAGGGACGCATTCAGGCCGACTTGAACCTCTTCTGTTTTGAGGACCGTTTTCTGATCGACACCGAG
CCCGAACTGCGCGAGAAGGTTTTGCCGCACATCAAGAAGTACATCATCGCCGATCAGGTGGAGCTGGAGGATGTTTCGGC
GGAGACGGCCGCGATCGGATTGGAAGGCCCGTCGGCAGCCACGATTCTGGCGACGCTCGGCGCGCCGGTTCCGGGCACGG
ACTACTCGCACGTGGCTTGGGACGATGCGACGATCGCCGCCGTGACCGTGACCGGCCAGCCGGGGGTCCGTATTTTTTGC
CCGCTCGAAAAGGCCGCGGCGTTCGTCCGCCAGTTTGAATCCGCCGGAGCCATGGCTGCGTCAGAAGATGACGTGCGCCT
GGCGCGCATCGAAAACGGCAGGCCCCGCTACGGCGAAGACATCCGCGACACCTCGCTGCCGCAGGAAACCCAGCAGATGC
ACGCCGTCAGTTTCACCAAGGGCTGCTATATTGGCCAGGAAATCGTGGAACGCATCCGCGCCCAGGGCCGGGTCAACAAA
AAGCTGACGCGAGTGGTGCTCCCCGGCTCTACGCTACCTGCGCACGGTGACAAAACCACAATCGATGGAGCCGACGCGGA
GGTGACGTCGGCCGTGCTATCCCCTGTGTCCGGAGAGATCGTAGCGCTGGCGTACGTGAGAACAACCTAG

Upstream 100 bases:

>100_bases
AAACCCGCGGCGCGCGCGGCAGTTGTTCGGCGCGGCCATTTCGGGGCTCACCATCATTCTGATTTCGGCCTACCTGAAGG
GCATCAACTAAACTGGAAGT

Downstream 100 bases:

>100_bases
AACTGAGTTGTTTTTGTTCGTGTTAATTCGTGGCCAGAGCTGTCCTTAGGCCTTTAGCTTTTCCAGCAGGTCGTCCGGGA
TGTGGAGGTTCCCGTTGCAG

Product: glycine cleavage T protein (aminomethyl transferase)

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTQGYEALRRGAAWIDLSKRGRIAVRGRDRARLLHAITSNEVKKMTPGSGCYAFLLSPQGRIQADLNLFCFEDRFLIDTE
PELREKVLPHIKKYIIADQVELEDVSAETAAIGLEGPSAATILATLGAPVPGTDYSHVAWDDATIAAVTVTGQPGVRIFC
PLEKAAAFVRQFESAGAMAASEDDVRLARIENGRPRYGEDIRDTSLPQETQQMHAVSFTKGCYIGQEIVERIRAQGRVNK
KLTRVVLPGSTLPAHGDKTTIDGADAEVTSAVLSPVSGEIVALAYVRTT

Sequences:

>Translated_289_residues
MTQGYEALRRGAAWIDLSKRGRIAVRGRDRARLLHAITSNEVKKMTPGSGCYAFLLSPQGRIQADLNLFCFEDRFLIDTE
PELREKVLPHIKKYIIADQVELEDVSAETAAIGLEGPSAATILATLGAPVPGTDYSHVAWDDATIAAVTVTGQPGVRIFC
PLEKAAAFVRQFESAGAMAASEDDVRLARIENGRPRYGEDIRDTSLPQETQQMHAVSFTKGCYIGQEIVERIRAQGRVNK
KLTRVVLPGSTLPAHGDKTTIDGADAEVTSAVLSPVSGEIVALAYVRTT
>Mature_288_residues
TQGYEALRRGAAWIDLSKRGRIAVRGRDRARLLHAITSNEVKKMTPGSGCYAFLLSPQGRIQADLNLFCFEDRFLIDTEP
ELREKVLPHIKKYIIADQVELEDVSAETAAIGLEGPSAATILATLGAPVPGTDYSHVAWDDATIAAVTVTGQPGVRIFCP
LEKAAAFVRQFESAGAMAASEDDVRLARIENGRPRYGEDIRDTSLPQETQQMHAVSFTKGCYIGQEIVERIRAQGRVNKK
LTRVVLPGSTLPAHGDKTTIDGADAEVTSAVLSPVSGEIVALAYVRTT

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0354

COG function: function code R; Predicted aminomethyltransferase related to GcvT

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Escherichia coli, GI1789272, Length=297, Percent_Identity=27.6094276094276, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789265, Length=259, Percent_Identity=25.4826254826255, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32563613, Length=306, Percent_Identity=25.4901960784314, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 31334; Mature: 31203

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQGYEALRRGAAWIDLSKRGRIAVRGRDRARLLHAITSNEVKKMTPGSGCYAFLLSPQG
CCCHHHHHHCCCEEEEECCCCEEEEECCHHHHHHHHHHCCCHHCCCCCCCEEEEEECCCC
RIQADLNLFCFEDRFLIDTEPELREKVLPHIKKYIIADQVELEDVSAETAAIGLEGPSAA
CEEECEEEEEEECEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCCHH
TILATLGAPVPGTDYSHVAWDDATIAAVTVTGQPGVRIFCPLEKAAAFVRQFESAGAMAA
HHEEECCCCCCCCCCCEEEECCCEEEEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCC
SEDDVRLARIENGRPRYGEDIRDTSLPQETQQMHAVSFTKGCYIGQEIVERIRAQGRVNK
CCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
KLTRVVLPGSTLPAHGDKTTIDGADAEVTSAVLSPVSGEIVALAYVRTT
CEEEEEECCCCCCCCCCCCEECCCCHHHHHHHHCCCCCCEEEEEEEECC
>Mature Secondary Structure 
TQGYEALRRGAAWIDLSKRGRIAVRGRDRARLLHAITSNEVKKMTPGSGCYAFLLSPQG
CCHHHHHHCCCEEEEECCCCEEEEECCHHHHHHHHHHCCCHHCCCCCCCEEEEEECCCC
RIQADLNLFCFEDRFLIDTEPELREKVLPHIKKYIIADQVELEDVSAETAAIGLEGPSAA
CEEECEEEEEEECEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCCHH
TILATLGAPVPGTDYSHVAWDDATIAAVTVTGQPGVRIFCPLEKAAAFVRQFESAGAMAA
HHEEECCCCCCCCCCCEEEECCCEEEEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCC
SEDDVRLARIENGRPRYGEDIRDTSLPQETQQMHAVSFTKGCYIGQEIVERIRAQGRVNK
CCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
KLTRVVLPGSTLPAHGDKTTIDGADAEVTSAVLSPVSGEIVALAYVRTT
CEEEEEECCCCCCCCCCCCEECCCCHHHHHHHHCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA