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The map label for this gene is lsrD [H]

Identifier: 116626853

GI number: 116626853

Start: 9806964

End: 9809012

Strand: Direct

Name: lsrD [H]

Synonym: Acid_7826

Alternate gene names: 116626853

Gene position: 9806964-9809012 (Clockwise)

Preceding gene: 116626852

Following gene: 116626856

Centisome position: 98.41

GC content: 63.25

Gene sequence:

>2049_bases
ATGGCAACGTCGTTGGCGCTCAGCGAGCATAGGCCGTGGCGCGAACGGCTCTTTCCCAATGGGGAGTGGGCGCTCGGCCT
GGCGCTCGCCGTGGAACTGGCGATCTTTGCCACGATCGGCGAGAACTTCTTCACGCTGGCGAATTTTTTCGAAGTGGTGC
GGCTGAGCGTCGAGCTCGGGCTGCTCGCGCTCGCCATGACGCCGATCATGATCACCGGCGGCATCGATCTTTCGGTGGGC
TCCACGATGGGGCTCGCTGCGGTGGTCTTCGGCGCGCTGTGGCGCGATGGCGGATGTTCCATCGCGGGGGCGGCCGGTGC
TGCGATTCTGCTGGGCTGCCTCGCGGGGCTGTTGAACGCGATGCTGATCACGCGGCTGAATATTCCGCCGCTGATTGTGA
CGCTGGGTTCGCTCTCACTCTTCCGCGGCATCGCCGAGGGCATCACCAGGGGCTCGGTGAACTATTCGGGCTTTCCCCAG
AGCTTTCTGAATCTCGGGCAGGGCTATCTCGGTGGCGTGGTGCCGGTGCAGTTTTCCATTCTGGTGATCGCGATTCTGGG
CTATTGGGTGCTACTGCACCGCTCCGTGATCGGGCGCACCATTTACGCGATCGGCTTCAGCCCGGGGGGCGCTCGCTATG
CGGGCATCCCCGCGCAGCGGCGCGTGGCGTTGCTCTACTTTTTATCGGGGCTCGTGGCCAGCGTGGCGGCCATCATCTAT
GTCGCGCACCTGGGCCAGGCGAAATCGGATGCAGGCACTGGTTACGAGCTGGCGGCGATCACAGCCGTGGTGCTGGGCGG
CACATCGGTCTTCGGCGGGCGCGGCACGGTTTGGGGCACGGTGCTCGGGCTGTTCGCGATCTCCGTCCTGCAGAACGGAC
TGCGGCTGGCGACGCTACCCTCCGAGATGACCGGCGTGCTGACCGGCGCGGTATTGATCCTGACCATCGGCTTGGGGCGG
CTACGCGGCGGCACTCAAACCAACGAAGCGACTCTTGACGAGGCTGATTCCATGAAGAACTCCCAACTTGCGATTCTCTG
CAGCGTAATTATCGGCGGATCGCTGATTGTGGCCGGCACCAATGTCTGGCTGATCCACTCGCTGCGGCCTACAGACGGCG
CACCCCCAGCAGCGGCCGCGAAGACCGGCAAGCGCCCGGTGATCGCCGTGATGCCAAAGGCCAAGGGCGACCCTTACTTC
ATCAGCTGCAAGGCCGGAGCGGAAGAGGCTGCCCGCGAGCTAGGTGTGGACCTGATCTGGGATGGTCCTACCGGCCTCGA
TGCCGCCAAGCAGAACGAAGTGGTGGAGGGTTGGATCACGCGCGGCGTGGACGCAATCGCGGTGTCGGTGGAGAATGGGC
CTGGCATTTCGACCGTGCTGCGCAAGGCGCGCGAGCGAGGCATCAAGGTGCTGACCTGGGACGCGGACGCGGCGCCGGAC
GCGCGCGATTACTTCATCAATCAGGCGACTCCGGAAGGCATTGGCAACACGCTCACCGACGAAGGCGCGCGCCTGATCGG
CGGCAAGGGAGAGTTCGCCATCGTCACCGGCGCGCTCGGCGCGGCGAATCAGAACGCGTGGATCGACTTCATCAAGAAGC
GCGTCGCCGAGAAGTATCCCCAGTTGAAACTGGTTACTATTCGGCCCAGCGACGACGATCGTGACAAGGCATTTTCGGAA
ACGCAGACGATCATGAAGGTCTATCCCAACGTGAAGTTGATCATTGCAATCTCCGCGCCCGCGGTTCCGGGAGCGGCGGA
GGCGGTGCAGCAGAGCGGCCGCAAGGACGTGGATGTGATCGGGCTATCGCTGCCCAATCTGTGTAAACGCTACGTGCACG
ATGGCGTGGCTCAGGCCGTGGTGCTGTGGAACACGAAGGATCTCGGCTACCTGACCGTGTACACAGCCGCGAAATTAGTG
CAGGGTCCGCTGGGCAGCGGGTCGTTCCAGGGCGGACGGTTGGGGACGATTGAGATACGCGGCACCGAAGTGATTCTCGG
GAAGCCGTTCATCTTCAATAAAGCGAATATCGATCAGTACGATTTCTAG

Upstream 100 bases:

>100_bases
ACGTTTCTCGGCCTGAGCGCTTATTGGGAACGCGCGATCGAAGGCGGCATCATTCTGGCGGCGGTATCGATGGATGCCGT
GCGCGTACATTCGGGGAAAT

Downstream 100 bases:

>100_bases
GGCGATCTCTGGTTGGCGATCGCTCCCTCACGGTTGCGGTTCGCGGGCGCGTAGTTGCTGGGCCGCGGCTTCCGGCGTGA
TGTCGCGCTGCGGCGTGGCC

Product: inner-membrane translocator

Products: NA

Alternate protein names: AI-2 import system permease protein lsrD [H]

Number of amino acids: Translated: 682; Mature: 681

Protein sequence:

>682_residues
MATSLALSEHRPWRERLFPNGEWALGLALAVELAIFATIGENFFTLANFFEVVRLSVELGLLALAMTPIMITGGIDLSVG
STMGLAAVVFGALWRDGGCSIAGAAGAAILLGCLAGLLNAMLITRLNIPPLIVTLGSLSLFRGIAEGITRGSVNYSGFPQ
SFLNLGQGYLGGVVPVQFSILVIAILGYWVLLHRSVIGRTIYAIGFSPGGARYAGIPAQRRVALLYFLSGLVASVAAIIY
VAHLGQAKSDAGTGYELAAITAVVLGGTSVFGGRGTVWGTVLGLFAISVLQNGLRLATLPSEMTGVLTGAVLILTIGLGR
LRGGTQTNEATLDEADSMKNSQLAILCSVIIGGSLIVAGTNVWLIHSLRPTDGAPPAAAAKTGKRPVIAVMPKAKGDPYF
ISCKAGAEEAARELGVDLIWDGPTGLDAAKQNEVVEGWITRGVDAIAVSVENGPGISTVLRKARERGIKVLTWDADAAPD
ARDYFINQATPEGIGNTLTDEGARLIGGKGEFAIVTGALGAANQNAWIDFIKKRVAEKYPQLKLVTIRPSDDDRDKAFSE
TQTIMKVYPNVKLIIAISAPAVPGAAEAVQQSGRKDVDVIGLSLPNLCKRYVHDGVAQAVVLWNTKDLGYLTVYTAAKLV
QGPLGSGSFQGGRLGTIEIRGTEVILGKPFIFNKANIDQYDF

Sequences:

>Translated_682_residues
MATSLALSEHRPWRERLFPNGEWALGLALAVELAIFATIGENFFTLANFFEVVRLSVELGLLALAMTPIMITGGIDLSVG
STMGLAAVVFGALWRDGGCSIAGAAGAAILLGCLAGLLNAMLITRLNIPPLIVTLGSLSLFRGIAEGITRGSVNYSGFPQ
SFLNLGQGYLGGVVPVQFSILVIAILGYWVLLHRSVIGRTIYAIGFSPGGARYAGIPAQRRVALLYFLSGLVASVAAIIY
VAHLGQAKSDAGTGYELAAITAVVLGGTSVFGGRGTVWGTVLGLFAISVLQNGLRLATLPSEMTGVLTGAVLILTIGLGR
LRGGTQTNEATLDEADSMKNSQLAILCSVIIGGSLIVAGTNVWLIHSLRPTDGAPPAAAAKTGKRPVIAVMPKAKGDPYF
ISCKAGAEEAARELGVDLIWDGPTGLDAAKQNEVVEGWITRGVDAIAVSVENGPGISTVLRKARERGIKVLTWDADAAPD
ARDYFINQATPEGIGNTLTDEGARLIGGKGEFAIVTGALGAANQNAWIDFIKKRVAEKYPQLKLVTIRPSDDDRDKAFSE
TQTIMKVYPNVKLIIAISAPAVPGAAEAVQQSGRKDVDVIGLSLPNLCKRYVHDGVAQAVVLWNTKDLGYLTVYTAAKLV
QGPLGSGSFQGGRLGTIEIRGTEVILGKPFIFNKANIDQYDF
>Mature_681_residues
ATSLALSEHRPWRERLFPNGEWALGLALAVELAIFATIGENFFTLANFFEVVRLSVELGLLALAMTPIMITGGIDLSVGS
TMGLAAVVFGALWRDGGCSIAGAAGAAILLGCLAGLLNAMLITRLNIPPLIVTLGSLSLFRGIAEGITRGSVNYSGFPQS
FLNLGQGYLGGVVPVQFSILVIAILGYWVLLHRSVIGRTIYAIGFSPGGARYAGIPAQRRVALLYFLSGLVASVAAIIYV
AHLGQAKSDAGTGYELAAITAVVLGGTSVFGGRGTVWGTVLGLFAISVLQNGLRLATLPSEMTGVLTGAVLILTIGLGRL
RGGTQTNEATLDEADSMKNSQLAILCSVIIGGSLIVAGTNVWLIHSLRPTDGAPPAAAAKTGKRPVIAVMPKAKGDPYFI
SCKAGAEEAARELGVDLIWDGPTGLDAAKQNEVVEGWITRGVDAIAVSVENGPGISTVLRKARERGIKVLTWDADAAPDA
RDYFINQATPEGIGNTLTDEGARLIGGKGEFAIVTGALGAANQNAWIDFIKKRVAEKYPQLKLVTIRPSDDDRDKAFSET
QTIMKVYPNVKLIIAISAPAVPGAAEAVQQSGRKDVDVIGLSLPNLCKRYVHDGVAQAVVLWNTKDLGYLTVYTAAKLVQ
GPLGSGSFQGGRLGTIEIRGTEVILGKPFIFNKANIDQYDF

Specific function: Part of the ABC transporter complex lsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787794, Length=301, Percent_Identity=37.2093023255814, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1787795, Length=315, Percent_Identity=33.3333333333333, Blast_Score=166, Evalue=6e-42,
Organism=Escherichia coli, GI1790191, Length=300, Percent_Identity=37, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1790524, Length=316, Percent_Identity=32.9113924050633, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788896, Length=325, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1787793, Length=293, Percent_Identity=34.8122866894198, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI87082395, Length=270, Percent_Identity=32.5925925925926, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI145693214, Length=254, Percent_Identity=35.4330708661417, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI145693152, Length=320, Percent_Identity=30.625, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1789992, Length=349, Percent_Identity=27.7936962750716, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788471, Length=282, Percent_Identity=31.2056737588652, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1790192, Length=274, Percent_Identity=25.1824817518248, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 71567; Mature: 71436

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSLALSEHRPWRERLFPNGEWALGLALAVELAIFATIGENFFTLANFFEVVRLSVELG
CCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LLALAMTPIMITGGIDLSVGSTMGLAAVVFGALWRDGGCSIAGAAGAAILLGCLAGLLNA
HHHHHHCCEEEECCCEEECCCHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHH
MLITRLNIPPLIVTLGSLSLFRGIAEGITRGSVNYSGFPQSFLNLGQGYLGGVVPVQFSI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHCCCCHHHHHHH
LVIAILGYWVLLHRSVIGRTIYAIGFSPGGARYAGIPAQRRVALLYFLSGLVASVAAIIY
HHHHHHHHHHHHHHHHHHCEEEEEEECCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHH
VAHLGQAKSDAGTGYELAAITAVVLGGTSVFGGRGTVWGTVLGLFAISVLQNGLRLATLP
HHHCCCCCCCCCCCEEHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHCCCEEEECC
SEMTGVLTGAVLILTIGLGRLRGGTQTNEATLDEADSMKNSQLAILCSVIIGGSLIVAGT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCEEEEEEC
NVWLIHSLRPTDGAPPAAAAKTGKRPVIAVMPKAKGDPYFISCKAGAEEAARELGVDLIW
CEEEEEEECCCCCCCCCHHHCCCCCCEEEEECCCCCCCEEEEECCCHHHHHHHCCCEEEE
DGPTGLDAAKQNEVVEGWITRGVDAIAVSVENGPGISTVLRKARERGIKVLTWDADAAPD
CCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCC
ARDYFINQATPEGIGNTLTDEGARLIGGKGEFAIVTGALGAANQNAWIDFIKKRVAEKYP
HHHHHCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCC
QLKLVTIRPSDDDRDKAFSETQTIMKVYPNVKLIIAISAPAVPGAAEAVQQSGRKDVDVI
CEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHCCCCCEEEE
GLSLPNLCKRYVHDGVAQAVVLWNTKDLGYLTVYTAAKLVQGPLGSGSFQGGRLGTIEIR
ECCHHHHHHHHHHCCHHCEEEEECCCCCCEEHHHHHHHHHCCCCCCCCCCCCEEEEEEEE
GTEVILGKPFIFNKANIDQYDF
CEEEEECCCEEECCCCCCCCCC
>Mature Secondary Structure 
ATSLALSEHRPWRERLFPNGEWALGLALAVELAIFATIGENFFTLANFFEVVRLSVELG
CCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LLALAMTPIMITGGIDLSVGSTMGLAAVVFGALWRDGGCSIAGAAGAAILLGCLAGLLNA
HHHHHHCCEEEECCCEEECCCHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHH
MLITRLNIPPLIVTLGSLSLFRGIAEGITRGSVNYSGFPQSFLNLGQGYLGGVVPVQFSI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHCCCCHHHHHHH
LVIAILGYWVLLHRSVIGRTIYAIGFSPGGARYAGIPAQRRVALLYFLSGLVASVAAIIY
HHHHHHHHHHHHHHHHHHCEEEEEEECCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHH
VAHLGQAKSDAGTGYELAAITAVVLGGTSVFGGRGTVWGTVLGLFAISVLQNGLRLATLP
HHHCCCCCCCCCCCEEHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHCCCEEEECC
SEMTGVLTGAVLILTIGLGRLRGGTQTNEATLDEADSMKNSQLAILCSVIIGGSLIVAGT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCEEEEEEC
NVWLIHSLRPTDGAPPAAAAKTGKRPVIAVMPKAKGDPYFISCKAGAEEAARELGVDLIW
CEEEEEEECCCCCCCCCHHHCCCCCCEEEEECCCCCCCEEEEECCCHHHHHHHCCCEEEE
DGPTGLDAAKQNEVVEGWITRGVDAIAVSVENGPGISTVLRKARERGIKVLTWDADAAPD
CCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCC
ARDYFINQATPEGIGNTLTDEGARLIGGKGEFAIVTGALGAANQNAWIDFIKKRVAEKYP
HHHHHCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCC
QLKLVTIRPSDDDRDKAFSETQTIMKVYPNVKLIIAISAPAVPGAAEAVQQSGRKDVDVI
CEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHCCCCCEEEE
GLSLPNLCKRYVHDGVAQAVVLWNTKDLGYLTVYTAAKLVQGPLGSGSFQGGRLGTIEIR
ECCHHHHHHHHHHCCHHCEEEEECCCCCCEEHHHHHHHHHCCCCCCCCCCCCEEEEEEEE
GTEVILGKPFIFNKANIDQYDF
CEEEEECCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA