Click here to switch to the map view.

The map label for this gene is xpsE [H]

Identifier: 116626805

GI number: 116626805

Start: 9760511

End: 9762211

Strand: Direct

Name: xpsE [H]

Synonym: Acid_7778

Alternate gene names: 116626805

Gene position: 9760511-9762211 (Clockwise)

Preceding gene: 116626804

Following gene: 116626806

Centisome position: 97.94

GC content: 63.61

Gene sequence:

>1701_bases
GTGGCCGCCACCATTCCCCCGCACCCCGAACCCGAGTCCGGAACCAACTCCGGGGTGCGCTACATGCGCCTCGGCGAAAT
CCTCATCGAGCGCGGAAAAATCGACGCCGAAGATCTCGAACGTGCCCTTGAGCTTCAGCTCGAGCGCGGCGATAAGCTCG
GCAAAATTGTCGTCGATATGGGCCTGATCGCGCAGCGCGATCTGCTCTCCGCCCTCAGCGACCAAATGGGCGTCCCGCTG
ATCGCGGTCGATGGCACGCCCCCCAATGCCCCCGAAATCGAAGGCCTTTCGCAGCGCTTCCTCCGCCAGTGCCGCGCCTT
CCCGGTCGCGCTCAACGACAGTGTCTTGACGATCGCCATGGCCGACCCGATGGACTTCGAAACCATCGCCGCCGTCCGTG
CCTTCAGCGGTCTCCAGGTCCAGACCGCGCTCGCCAGCGAACAGGAAATCCTCGACGCCATCGACCGCAACTATGGCGAG
AGCGACCAGAAGACCTTCATCGGCGAAGGCGACGACGAGCAGGCCAACGCCGATCTCGAACACCTGCGCGACATGGCGAG
CGAAGCGCCCGTCATCCGCCTGGTCAACGCCATGATCGCCGACGCCATCGAGAAGCGCGCCAGCGATATTCACATCGAGC
CCTTCGAGAAGGAATTCCGCATCCGCTTCCGCGTGGACGGCGTGCTCTTCGCCCAGGAAAATCCGCCGCGCGAGCTCAAG
GCCGCCATCATCAGCCGCCTCAAGCTGATGGCGAAGCTCAATATCGCCGAACGCCGCCTGCCGCAGGATGGCCGCATCAA
AATAAAGATCCTCGGCCGCGAAGTCGATCTCCGCGTCTCCACGCTCCCCACCCTCTACGGCGAAAGCGTCGTGATGCGCT
TGCTCGATCGCTCCTCCGGCGATTTCTACGACCTCCGCCGCCTCGGCTTCGACGACCACATGCTCCGCCAGATGGAGCAC
TTCACCAGCATGCCCCACGGCATTTTCCTGGTCACAGGCCCCACCGGCAGTGGAAAATCGACCACGCTCTACTCCGCCCT
CAAGCGCATCAACCTGCCGGACAAAAAGATCATCACCATCGAAGACCCGGTCGAATACCAGATGGACGGGATCAACCAGA
TCCACGTCAATCCGCAAATCGGACTGACCTTCGCCGCCGGCTTGCGCCACATCGTGCGCCAGGACCCCGACGTCATCATG
GTCGGCGAAATCCGCGATCGCGAGACCGCCGATATCGCCATCCGCGCCGCGCTCACCGGCCACCTGGTGTTTTCTTCGCT
TCACACCAACGACGCTCCCAGCGCCATCACCCGCCTGGTCGATATGGGCGTCGAGAACTATCTGATCACCAGCTCCCTGG
TCGCCGTCTTGGCGCAGCGCCTGGTTCGAGTGATCTGTCCGCAGTGCAAGATCTTCGCCGGGGAAGTCCTCTCGCCCGAA
GGCGAAATGATGGAAACCTGGCGCGGCCAGGGCTGCGATCACTGCGGCGGCCGCGGCTACCACGCCCGCATGGGCATCTT
CGAGATGATGGACGTCAGCGACGAGGTCCGCAAGCTCATCATGGGCAATGCCGACGCCAGCATCCTCACCCGCGCCGCCC
GCAAGAACGGCATGCGCAACCTCCGCGAGGACGGCTGGCGCAAAATCCGCGACGGCGTCACCACCGTCGAAGAAGTCATG
CGCGTCACCCAGGAGTTCTAG

Upstream 100 bases:

>100_bases
ACGGCACCTGGGAAAACACCGCGGGCATGCCCGCTGAAGTAGTCATGCGCGCCGCGCGCGCCAACGCCGCAGCCGGCGTC
GTCGAAACGGAAGAACGATA

Downstream 100 bases:

>100_bases
CCATGACTCCCGCACGCACCTCCCTCACTCACCTGCATCCCTTGCCCCCGTGCATCGCCCCCCAACGAGCCGCGACCGTC
AGGGAGCGCCGAGCCCTCGC

Product: type II secretion system protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MAATIPPHPEPESGTNSGVRYMRLGEILIERGKIDAEDLERALELQLERGDKLGKIVVDMGLIAQRDLLSALSDQMGVPL
IAVDGTPPNAPEIEGLSQRFLRQCRAFPVALNDSVLTIAMADPMDFETIAAVRAFSGLQVQTALASEQEILDAIDRNYGE
SDQKTFIGEGDDEQANADLEHLRDMASEAPVIRLVNAMIADAIEKRASDIHIEPFEKEFRIRFRVDGVLFAQENPPRELK
AAIISRLKLMAKLNIAERRLPQDGRIKIKILGREVDLRVSTLPTLYGESVVMRLLDRSSGDFYDLRRLGFDDHMLRQMEH
FTSMPHGIFLVTGPTGSGKSTTLYSALKRINLPDKKIITIEDPVEYQMDGINQIHVNPQIGLTFAAGLRHIVRQDPDVIM
VGEIRDRETADIAIRAALTGHLVFSSLHTNDAPSAITRLVDMGVENYLITSSLVAVLAQRLVRVICPQCKIFAGEVLSPE
GEMMETWRGQGCDHCGGRGYHARMGIFEMMDVSDEVRKLIMGNADASILTRAARKNGMRNLREDGWRKIRDGVTTVEEVM
RVTQEF

Sequences:

>Translated_566_residues
MAATIPPHPEPESGTNSGVRYMRLGEILIERGKIDAEDLERALELQLERGDKLGKIVVDMGLIAQRDLLSALSDQMGVPL
IAVDGTPPNAPEIEGLSQRFLRQCRAFPVALNDSVLTIAMADPMDFETIAAVRAFSGLQVQTALASEQEILDAIDRNYGE
SDQKTFIGEGDDEQANADLEHLRDMASEAPVIRLVNAMIADAIEKRASDIHIEPFEKEFRIRFRVDGVLFAQENPPRELK
AAIISRLKLMAKLNIAERRLPQDGRIKIKILGREVDLRVSTLPTLYGESVVMRLLDRSSGDFYDLRRLGFDDHMLRQMEH
FTSMPHGIFLVTGPTGSGKSTTLYSALKRINLPDKKIITIEDPVEYQMDGINQIHVNPQIGLTFAAGLRHIVRQDPDVIM
VGEIRDRETADIAIRAALTGHLVFSSLHTNDAPSAITRLVDMGVENYLITSSLVAVLAQRLVRVICPQCKIFAGEVLSPE
GEMMETWRGQGCDHCGGRGYHARMGIFEMMDVSDEVRKLIMGNADASILTRAARKNGMRNLREDGWRKIRDGVTTVEEVM
RVTQEF
>Mature_565_residues
AATIPPHPEPESGTNSGVRYMRLGEILIERGKIDAEDLERALELQLERGDKLGKIVVDMGLIAQRDLLSALSDQMGVPLI
AVDGTPPNAPEIEGLSQRFLRQCRAFPVALNDSVLTIAMADPMDFETIAAVRAFSGLQVQTALASEQEILDAIDRNYGES
DQKTFIGEGDDEQANADLEHLRDMASEAPVIRLVNAMIADAIEKRASDIHIEPFEKEFRIRFRVDGVLFAQENPPRELKA
AIISRLKLMAKLNIAERRLPQDGRIKIKILGREVDLRVSTLPTLYGESVVMRLLDRSSGDFYDLRRLGFDDHMLRQMEHF
TSMPHGIFLVTGPTGSGKSTTLYSALKRINLPDKKIITIEDPVEYQMDGINQIHVNPQIGLTFAAGLRHIVRQDPDVIMV
GEIRDRETADIAIRAALTGHLVFSSLHTNDAPSAITRLVDMGVENYLITSSLVAVLAQRLVRVICPQCKIFAGEVLSPEG
EMMETWRGQGCDHCGGRGYHARMGIFEMMDVSDEVRKLIMGNADASILTRAARKNGMRNLREDGWRKIRDGVTTVEEVMR
VTQEF

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=450, Percent_Identity=47.5555555555556, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI1786296, Length=377, Percent_Identity=45.0928381962865, Blast_Score=338, Evalue=6e-94,
Organism=Escherichia coli, GI87082188, Length=279, Percent_Identity=35.1254480286738, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007831
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E; PF05157 GSPII_E_N [H]

EC number: NA

Molecular weight: Translated: 63046; Mature: 62915

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATIPPHPEPESGTNSGVRYMRLGEILIERGKIDAEDLERALELQLERGDKLGKIVVDM
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
GLIAQRDLLSALSDQMGVPLIAVDGTPPNAPEIEGLSQRFLRQCRAFPVALNDSVLTIAM
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEECCCEEEEEE
ADPMDFETIAAVRAFSGLQVQTALASEQEILDAIDRNYGESDQKTFIGEGDDEQANADLE
CCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHH
HLRDMASEAPVIRLVNAMIADAIEKRASDIHIEPFEKEFRIRFRVDGVLFAQENPPRELK
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEECCCCCHHHH
AAIISRLKLMAKLNIAERRLPQDGRIKIKILGREVDLRVSTLPTLYGESVVMRLLDRSSG
HHHHHHHHHHHHHCHHHHCCCCCCCEEEEEECCEEEEEEHHCCHHHHHHHHHHHHHCCCC
DFYDLRRLGFDDHMLRQMEHFTSMPHGIFLVTGPTGSGKSTTLYSALKRINLPDKKIITI
CHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEE
EDPVEYQMDGINQIHVNPQIGLTFAAGLRHIVRQDPDVIMVGEIRDRETADIAIRAALTG
CCCCHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHEEEHHHHHH
HLVFSSLHTNDAPSAITRLVDMGVENYLITSSLVAVLAQRLVRVICPQCKIFAGEVLSPE
HHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCC
GEMMETWRGQGCDHCGGRGYHARMGIFEMMDVSDEVRKLIMGNADASILTRAARKNGMRN
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LREDGWRKIRDGVTTVEEVMRVTQEF
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AATIPPHPEPESGTNSGVRYMRLGEILIERGKIDAEDLERALELQLERGDKLGKIVVDM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
GLIAQRDLLSALSDQMGVPLIAVDGTPPNAPEIEGLSQRFLRQCRAFPVALNDSVLTIAM
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEECCCEEEEEE
ADPMDFETIAAVRAFSGLQVQTALASEQEILDAIDRNYGESDQKTFIGEGDDEQANADLE
CCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHH
HLRDMASEAPVIRLVNAMIADAIEKRASDIHIEPFEKEFRIRFRVDGVLFAQENPPRELK
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEECCCCCHHHH
AAIISRLKLMAKLNIAERRLPQDGRIKIKILGREVDLRVSTLPTLYGESVVMRLLDRSSG
HHHHHHHHHHHHHCHHHHCCCCCCCEEEEEECCEEEEEEHHCCHHHHHHHHHHHHHCCCC
DFYDLRRLGFDDHMLRQMEHFTSMPHGIFLVTGPTGSGKSTTLYSALKRINLPDKKIITI
CHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEE
EDPVEYQMDGINQIHVNPQIGLTFAAGLRHIVRQDPDVIMVGEIRDRETADIAIRAALTG
CCCCHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHEEEHHHHHH
HLVFSSLHTNDAPSAITRLVDMGVENYLITSSLVAVLAQRLVRVICPQCKIFAGEVLSPE
HHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCC
GEMMETWRGQGCDHCGGRGYHARMGIFEMMDVSDEVRKLIMGNADASILTRAARKNGMRN
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LREDGWRKIRDGVTTVEEVMRVTQEF
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1944223; 12024217 [H]