Click here to switch to the map view.

The map label for this gene is yrbE [H]

Identifier: 116626768

GI number: 116626768

Start: 9720008

End: 9721168

Strand: Direct

Name: yrbE [H]

Synonym: Acid_7741

Alternate gene names: 116626768

Gene position: 9720008-9721168 (Clockwise)

Preceding gene: 116626767

Following gene: 116626769

Centisome position: 97.54

GC content: 62.53

Gene sequence:

>1161_bases
ATGAAGAAGCTCAACATCGGAATGATCGGCTACGGGTTCATGGGACGGACCCACTCCAACGCCTTCTCGCAGGTGAATCA
CTTCTTCGACGTGCCCTATCAGCCCGTACTGAAAACGGTGTGCGCACGCAACGCGGATCGCGCTAAGGCGTTCGCCTCCA
AGTGGGGCTATGAATCGGTGGAGCCGGACTGGCGCAAGGTGGTGGAATCGCCCGAGATCGACCTGATCGATATCGCCAGC
CCGAACGACACGCACGCGGAGATCGCGGTGGCGGCGGCCAAGGCGGGCAAGATGGTGATGTGCGAGAAGCCGCTGGGCCG
CAACGCCGCCGAGGGGGAGACCATGGTGAAGGCCGTGGAAGCCGCCGGCGTGCCGAACATGGTCTGGTACAACTACCGGC
GCGTGCCGGCGGTGATGCTGGCCAAGCAACTGATCGACGAAGGCCGGCTCGGACGCATCTTCCACTATCGCGCGAAGTTC
CTTCAGGACTGGACGATCTCAAGTGACCTGCCGCAGGGCGGCGAAGGGCTGTGGCGGCTCGATGTGGCGGTGGCGGGCAG
CGGCGTCACGGGCGACCTGCTGGCGCACTGCATCGATACGGCGATGTGGCTCAACGGCGGCATCGACGAAGTTACCGGCG
CTACAGAGACGTTTATCAAGGCGCGGCAGCATAACCTCACGGGAAAACTGGAGCCTGTGGGAATCGACGACGCCAGCCTC
TTTCTGGCGCGCTTCAACAACGGCTCGCTCGCAACCTTCGAGGCCACGCGGTATGCGCGCGGGCACAAGGCGCTCTACAC
CCTGGAGATCAACGGCGAGAAGGCGTCCATCATTTGGGACCTGCACGACCTGCATCGCCTGCAGTACTTCGACCATCGCG
ATGAGGGCCGCCTGCGCGGTTGGAAGAGCGTGCACATTACCGATTCCGATCATCCTTATATGAAGCATTGGTGGGTGCCC
GGCCTGCAGATTGGCTACGAGCATACGTTCATTCACCAGGCCGCCGATTTCCTGAGCGCGCTCGGTGAGGGCAAGAGCGC
CGCGCCGACTTTCCGCGAGGCGCTGCTTACGGACTACGTGACGGATGCGGTGCTCGCGTCCGCGCAAAATCGCAAGTGGG
TCAAAGTTCAAGGGTCGGAAAAACTGGAGGCCGCATGTTAG

Upstream 100 bases:

>100_bases
GGCTGCATGTTCCCGAATTCGATGATGCTCGATCCCAAGACGTGGCAGGACGTGCTGCGGGTGATGATCGCGGTGCGCGA
TGCGCACGGGTGGAACTGAC

Downstream 100 bases:

>100_bases
TACGTTTCGCAGCGTTGGCGATCATTTCAGGCGCACTGTTGGCGCAGCAGACTCCCGCTCCGGCGGTGAATGCCGGGCGC
GGGGCAGGACGCGGCGCGGG

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKKLNIGMIGYGFMGRTHSNAFSQVNHFFDVPYQPVLKTVCARNADRAKAFASKWGYESVEPDWRKVVESPEIDLIDIAS
PNDTHAEIAVAAAKAGKMVMCEKPLGRNAAEGETMVKAVEAAGVPNMVWYNYRRVPAVMLAKQLIDEGRLGRIFHYRAKF
LQDWTISSDLPQGGEGLWRLDVAVAGSGVTGDLLAHCIDTAMWLNGGIDEVTGATETFIKARQHNLTGKLEPVGIDDASL
FLARFNNGSLATFEATRYARGHKALYTLEINGEKASIIWDLHDLHRLQYFDHRDEGRLRGWKSVHITDSDHPYMKHWWVP
GLQIGYEHTFIHQAADFLSALGEGKSAAPTFREALLTDYVTDAVLASAQNRKWVKVQGSEKLEAAC

Sequences:

>Translated_386_residues
MKKLNIGMIGYGFMGRTHSNAFSQVNHFFDVPYQPVLKTVCARNADRAKAFASKWGYESVEPDWRKVVESPEIDLIDIAS
PNDTHAEIAVAAAKAGKMVMCEKPLGRNAAEGETMVKAVEAAGVPNMVWYNYRRVPAVMLAKQLIDEGRLGRIFHYRAKF
LQDWTISSDLPQGGEGLWRLDVAVAGSGVTGDLLAHCIDTAMWLNGGIDEVTGATETFIKARQHNLTGKLEPVGIDDASL
FLARFNNGSLATFEATRYARGHKALYTLEINGEKASIIWDLHDLHRLQYFDHRDEGRLRGWKSVHITDSDHPYMKHWWVP
GLQIGYEHTFIHQAADFLSALGEGKSAAPTFREALLTDYVTDAVLASAQNRKWVKVQGSEKLEAAC
>Mature_386_residues
MKKLNIGMIGYGFMGRTHSNAFSQVNHFFDVPYQPVLKTVCARNADRAKAFASKWGYESVEPDWRKVVESPEIDLIDIAS
PNDTHAEIAVAAAKAGKMVMCEKPLGRNAAEGETMVKAVEAAGVPNMVWYNYRRVPAVMLAKQLIDEGRLGRIFHYRAKF
LQDWTISSDLPQGGEGLWRLDVAVAGSGVTGDLLAHCIDTAMWLNGGIDEVTGATETFIKARQHNLTGKLEPVGIDDASL
FLARFNNGSLATFEATRYARGHKALYTLEINGEKASIIWDLHDLHRLQYFDHRDEGRLRGWKSVHITDSDHPYMKHWWVP
GLQIGYEHTFIHQAADFLSALGEGKSAAPTFREALLTDYVTDAVLASAQNRKWVKVQGSEKLEAAC

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87081947, Length=204, Percent_Identity=27.9411764705882, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87082405, Length=286, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787574, Length=280, Percent_Identity=23.2142857142857, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323975, Length=152, Percent_Identity=28.2894736842105, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581117, Length=243, Percent_Identity=27.5720164609054, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 42976; Mature: 42976

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLNIGMIGYGFMGRTHSNAFSQVNHFFDVPYQPVLKTVCARNADRAKAFASKWGYESV
CCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCC
EPDWRKVVESPEIDLIDIASPNDTHAEIAVAAAKAGKMVMCEKPLGRNAAEGETMVKAVE
CHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHH
AAGVPNMVWYNYRRVPAVMLAKQLIDEGRLGRIFHYRAKFLQDWTISSDLPQGGEGLWRL
HCCCCCCEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
DVAVAGSGVTGDLLAHCIDTAMWLNGGIDEVTGATETFIKARQHNLTGKLEPVGIDDASL
EEEEECCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHEE
FLARFNNGSLATFEATRYARGHKALYTLEINGEKASIIWDLHDLHRLQYFDHRDEGRLRG
EEEEECCCCEEEEEHHHHCCCCCEEEEEEECCCEEEEEEEHHHHHHHHHCCCCCCCCCCC
WKSVHITDSDHPYMKHWWVPGLQIGYEHTFIHQAADFLSALGEGKSAAPTFREALLTDYV
CEEEEEECCCCCCHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TDAVLASAQNRKWVKVQGSEKLEAAC
HHHHHHHCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MKKLNIGMIGYGFMGRTHSNAFSQVNHFFDVPYQPVLKTVCARNADRAKAFASKWGYESV
CCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCC
EPDWRKVVESPEIDLIDIASPNDTHAEIAVAAAKAGKMVMCEKPLGRNAAEGETMVKAVE
CHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHH
AAGVPNMVWYNYRRVPAVMLAKQLIDEGRLGRIFHYRAKFLQDWTISSDLPQGGEGLWRL
HCCCCCCEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
DVAVAGSGVTGDLLAHCIDTAMWLNGGIDEVTGATETFIKARQHNLTGKLEPVGIDDASL
EEEEECCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHEE
FLARFNNGSLATFEATRYARGHKALYTLEINGEKASIIWDLHDLHRLQYFDHRDEGRLRG
EEEEECCCCEEEEEHHHHCCCCCEEEEEEECCCEEEEEEEHHHHHHHHHCCCCCCCCCCC
WKSVHITDSDHPYMKHWWVPGLQIGYEHTFIHQAADFLSALGEGKSAAPTFREALLTDYV
CEEEEEECCCCCCHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TDAVLASAQNRKWVKVQGSEKLEAAC
HHHHHHHCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]