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The map label for this gene is atoS [H]

Identifier: 116626468

GI number: 116626468

Start: 9321947

End: 9323782

Strand: Direct

Name: atoS [H]

Synonym: Acid_7431

Alternate gene names: 116626468

Gene position: 9321947-9323782 (Clockwise)

Preceding gene: 116626467

Following gene: 116626469

Centisome position: 93.54

GC content: 62.36

Gene sequence:

>1836_bases
ATGACCCTGCAGGCCAAGCTGACGCTCGGCTCCGTGCTGCTGGCGACACTGATCGTGTCGTTCATCTCCGCGGTGGATCT
GGGCAATCTGATGCAACTGGAGTTTCAGGGCGTATACGAACGCGCCGACCTGGTCAAGGATCTCTCCAAGGATGCGGTCA
TCGATACGCTGAATCGCCCCCGGGATGTGAATCTGCGCGAGGCGCTCGGGGACCCGGAACTCAGGCAGAAGCTGCTCAAT
CTGCTCAGCTCCTCGAAGGCCATCTTTTCCATCGACCTGGTCTCGGTCGAAAACAACGAAATCATGGCGAGCACGTTGAA
GAGCCGCGTGGGCTCGATCGCCTATCCCACGCCTCCCGATTTCGCACCGCTGGTCAAGGAAAAGGGCTGGGTGGAAAAGA
TGAAGGTGCTGTTCAGCCAGGAGCCACAGTACTACATGCTCCAGGAGCCGCTGGGTTCAGGCGACGTTACGATCTTTTTC
GTGCGCGTGATTATCCATCCGGCCTTTTTGCGGGAGCCGCTCACCGAGACATTCCTGCGCCATGCCAAAGTGGCCGGCCT
TTCGATCGTGCTGGCGGTGTTCCTGACCTTTCTGTTTTCGATGGTCGCCTTTCGCAAACTGGGGCGCATCGGACAAATGC
TCGACCTTGCGGCGCGCGGTGAATTCGAGCCCGCGCCGCCGGATTCCAAGACGGCGACCGACGAGCTTTCCGTAATGGCC
TCGAAAGTGACTCTGCTGGGCCAGCGATTGCGCGGCGCACAGTTTGAAGTCTCCGATCTGCGCGGGAACATCGACCACCT
GCTGCAAGATCTGGAGGACGGGGTATTTGTCTTCAATCGCGAATTCCGGCTGGTCTTCGCCTCGGGCTCGGTGGAAAAGT
TCCTGGGCCGCGACCGCTCCGACCTTCCCGGCCAGCTGCTCGCCGACGTGTTCCCACCGTCCACCATGCTGGGGCTGCTC
ATCGCGCAGGCGTCGCAAACCGGGCGTCCGCTGCACCACCGGCGCGTGCCGGTGACACCAGCGGGAGACGGCGCGTCCGG
GGCTACGGTGGTGCTGCTCTCGGTCGACAACCTGGAAAGCGTTCCGGGCGGCCCCAGCGGCGGCAGCGGAATTCTGGTAC
GGCTGCGCGACCCCGAAGCGCAGCGCAAGATCAATCGCGAACTGCAAACCGCCGATCGCCTGTCCGCCATCAGCCGGATT
TCCAGCGGCGTGGCGCACGAGGTGAAGAATCCGCTCAACGCCATCCTGTTGCACGTGGAGGTGGCACGCGGCAAACTCTC
GCACGGGAACACGGACGTGGCGCCGCAAATGGAGATCATCGCGCGCGAGATCCTGCGGCTGGATCGCGTGGTGCGCACGT
TCCTGGATTTCACGCGCCCGGTGGAGCTCAAGCTGGCCACGGTTTCGATGCGCGAACTGGTGCAGGAGATCGTGGAACTG
GCGCGCCCGCAGGCCGCCGCCGCCGGAATCGGCGTCACCGTGCGCGATGAGGCGGAAGGCGTGGACGTGCGGGTAGACCG
CGATTTGTTCAAGCAGGCCGTGCTTAACATCGTAGTAAACGGGATGCAGGCGATGCCGGAAGGCGGCGAGCTCCGCTTCG
AGGCGACCGCGGGAGAAAACGGCACGGAGTTGCGCATCTCCGACACAGGGACTGGAATTCCCGAAGCCTTGCGCGAAAAG
ATCTTCCGCTTGTACTTCAGCACAAAGAAGGAGGGATCGGGTATAGGCCTGGCGATGACGTTCCGGATCGTGCAATTGCA
CGATGGTACAATCGATTTCACCAGTGAGCCGGGGAAGGGAACCACCTTCCTGATCCGCCTGCCCATCGCAGTGTGA

Upstream 100 bases:

>100_bases
ATCGACCGCACCTACCCGCTGGCGGACGCGGCGTCGGCGCACCGCGATTTGGAAAGCCGCAAGACCGCGGGCAAGCTGGT
ACTCGCGGTTTCGTGATCCG

Downstream 100 bases:

>100_bases
GAATAAAAGTGATGCGCGGTACGGTCGTCCTCATTATCGTCTCCCTGCTTGGGTTGGTTTCCTGCGCGAAACGCGCTCCC
AAAGCCGCCGTGCCGGTGAC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MTLQAKLTLGSVLLATLIVSFISAVDLGNLMQLEFQGVYERADLVKDLSKDAVIDTLNRPRDVNLREALGDPELRQKLLN
LLSSSKAIFSIDLVSVENNEIMASTLKSRVGSIAYPTPPDFAPLVKEKGWVEKMKVLFSQEPQYYMLQEPLGSGDVTIFF
VRVIIHPAFLREPLTETFLRHAKVAGLSIVLAVFLTFLFSMVAFRKLGRIGQMLDLAARGEFEPAPPDSKTATDELSVMA
SKVTLLGQRLRGAQFEVSDLRGNIDHLLQDLEDGVFVFNREFRLVFASGSVEKFLGRDRSDLPGQLLADVFPPSTMLGLL
IAQASQTGRPLHHRRVPVTPAGDGASGATVVLLSVDNLESVPGGPSGGSGILVRLRDPEAQRKINRELQTADRLSAISRI
SSGVAHEVKNPLNAILLHVEVARGKLSHGNTDVAPQMEIIAREILRLDRVVRTFLDFTRPVELKLATVSMRELVQEIVEL
ARPQAAAAGIGVTVRDEAEGVDVRVDRDLFKQAVLNIVVNGMQAMPEGGELRFEATAGENGTELRISDTGTGIPEALREK
IFRLYFSTKKEGSGIGLAMTFRIVQLHDGTIDFTSEPGKGTTFLIRLPIAV

Sequences:

>Translated_611_residues
MTLQAKLTLGSVLLATLIVSFISAVDLGNLMQLEFQGVYERADLVKDLSKDAVIDTLNRPRDVNLREALGDPELRQKLLN
LLSSSKAIFSIDLVSVENNEIMASTLKSRVGSIAYPTPPDFAPLVKEKGWVEKMKVLFSQEPQYYMLQEPLGSGDVTIFF
VRVIIHPAFLREPLTETFLRHAKVAGLSIVLAVFLTFLFSMVAFRKLGRIGQMLDLAARGEFEPAPPDSKTATDELSVMA
SKVTLLGQRLRGAQFEVSDLRGNIDHLLQDLEDGVFVFNREFRLVFASGSVEKFLGRDRSDLPGQLLADVFPPSTMLGLL
IAQASQTGRPLHHRRVPVTPAGDGASGATVVLLSVDNLESVPGGPSGGSGILVRLRDPEAQRKINRELQTADRLSAISRI
SSGVAHEVKNPLNAILLHVEVARGKLSHGNTDVAPQMEIIAREILRLDRVVRTFLDFTRPVELKLATVSMRELVQEIVEL
ARPQAAAAGIGVTVRDEAEGVDVRVDRDLFKQAVLNIVVNGMQAMPEGGELRFEATAGENGTELRISDTGTGIPEALREK
IFRLYFSTKKEGSGIGLAMTFRIVQLHDGTIDFTSEPGKGTTFLIRLPIAV
>Mature_610_residues
TLQAKLTLGSVLLATLIVSFISAVDLGNLMQLEFQGVYERADLVKDLSKDAVIDTLNRPRDVNLREALGDPELRQKLLNL
LSSSKAIFSIDLVSVENNEIMASTLKSRVGSIAYPTPPDFAPLVKEKGWVEKMKVLFSQEPQYYMLQEPLGSGDVTIFFV
RVIIHPAFLREPLTETFLRHAKVAGLSIVLAVFLTFLFSMVAFRKLGRIGQMLDLAARGEFEPAPPDSKTATDELSVMAS
KVTLLGQRLRGAQFEVSDLRGNIDHLLQDLEDGVFVFNREFRLVFASGSVEKFLGRDRSDLPGQLLADVFPPSTMLGLLI
AQASQTGRPLHHRRVPVTPAGDGASGATVVLLSVDNLESVPGGPSGGSGILVRLRDPEAQRKINRELQTADRLSAISRIS
SGVAHEVKNPLNAILLHVEVARGKLSHGNTDVAPQMEIIAREILRLDRVVRTFLDFTRPVELKLATVSMRELVQEIVELA
RPQAAAAGIGVTVRDEAEGVDVRVDRDLFKQAVLNIVVNGMQAMPEGGELRFEATAGENGTELRISDTGTGIPEALREKI
FRLYFSTKKEGSGIGLAMTFRIVQLHDGTIDFTSEPGKGTTFLIRLPIAV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=393, Percent_Identity=28.7531806615776, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=31.858407079646, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1790300, Length=256, Percent_Identity=30.078125, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789149, Length=260, Percent_Identity=27.6923076923077, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=215, Percent_Identity=24.6511627906977, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI48994928, Length=359, Percent_Identity=24.5125348189415, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI145693157, Length=219, Percent_Identity=24.6575342465753, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1790346, Length=225, Percent_Identity=24.4444444444444, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=24.2553191489362, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=26.6666666666667, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790861, Length=225, Percent_Identity=27.1111111111111, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66827; Mature: 66696

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQAKLTLGSVLLATLIVSFISAVDLGNLMQLEFQGVYERADLVKDLSKDAVIDTLNRP
CCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
RDVNLREALGDPELRQKLLNLLSSSKAIFSIDLVSVENNEIMASTLKSRVGSIAYPTPPD
CCCCHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCC
FAPLVKEKGWVEKMKVLFSQEPQYYMLQEPLGSGDVTIFFVRVIIHPAFLREPLTETFLR
CHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HAKVAGLSIVLAVFLTFLFSMVAFRKLGRIGQMLDLAARGEFEPAPPDSKTATDELSVMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
SKVTLLGQRLRGAQFEVSDLRGNIDHLLQDLEDGVFVFNREFRLVFASGSVEKFLGRDRS
HHHHHHHHHHCCCCEEHHHHCCCHHHHHHHHCCCEEEEECEEEEEEECCCHHHHHCCCCC
DLPGQLLADVFPPSTMLGLLIAQASQTGRPLHHRRVPVTPAGDGASGATVVLLSVDNLES
CCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCEEEEEEECCCCC
VPGGPSGGSGILVRLRDPEAQRKINRELQTADRLSAISRISSGVAHEVKNPLNAILLHVE
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEE
VARGKLSHGNTDVAPQMEIIAREILRLDRVVRTFLDFTRPVELKLATVSMRELVQEIVEL
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH
ARPQAAAAGIGVTVRDEAEGVDVRVDRDLFKQAVLNIVVNGMQAMPEGGELRFEATAGEN
HCCCHHHCCCCEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GTELRISDTGTGIPEALREKIFRLYFSTKKEGSGIGLAMTFRIVQLHDGTIDFTSEPGKG
CCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCEEEECCCCCCC
TTFLIRLPIAV
CEEEEEECCCC
>Mature Secondary Structure 
TLQAKLTLGSVLLATLIVSFISAVDLGNLMQLEFQGVYERADLVKDLSKDAVIDTLNRP
CEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
RDVNLREALGDPELRQKLLNLLSSSKAIFSIDLVSVENNEIMASTLKSRVGSIAYPTPPD
CCCCHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCC
FAPLVKEKGWVEKMKVLFSQEPQYYMLQEPLGSGDVTIFFVRVIIHPAFLREPLTETFLR
CHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HAKVAGLSIVLAVFLTFLFSMVAFRKLGRIGQMLDLAARGEFEPAPPDSKTATDELSVMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
SKVTLLGQRLRGAQFEVSDLRGNIDHLLQDLEDGVFVFNREFRLVFASGSVEKFLGRDRS
HHHHHHHHHHCCCCEEHHHHCCCHHHHHHHHCCCEEEEECEEEEEEECCCHHHHHCCCCC
DLPGQLLADVFPPSTMLGLLIAQASQTGRPLHHRRVPVTPAGDGASGATVVLLSVDNLES
CCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCEEEEEEECCCCC
VPGGPSGGSGILVRLRDPEAQRKINRELQTADRLSAISRISSGVAHEVKNPLNAILLHVE
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEE
VARGKLSHGNTDVAPQMEIIAREILRLDRVVRTFLDFTRPVELKLATVSMRELVQEIVEL
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH
ARPQAAAAGIGVTVRDEAEGVDVRVDRDLFKQAVLNIVVNGMQAMPEGGELRFEATAGEN
HCCCHHHCCCCEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GTELRISDTGTGIPEALREKIFRLYFSTKKEGSGIGLAMTFRIVQLHDGTIDFTSEPGKG
CCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCEEEECCCCCCC
TTFLIRLPIAV
CEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]