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The map label for this gene is qor [H]

Identifier: 116626467

GI number: 116626467

Start: 9320971

End: 9321942

Strand: Direct

Name: qor [H]

Synonym: Acid_7430

Alternate gene names: 116626467

Gene position: 9320971-9321942 (Clockwise)

Preceding gene: 116626466

Following gene: 116626468

Centisome position: 93.53

GC content: 62.45

Gene sequence:

>972_bases
ATGAAAGCTATACAAGTCCTAACTCCCGGCGGGCCAGAGAGTTTGCACCTGTTGGACGCACCAGTACCGCGGCTTGGGCC
GGATCAGGCGCTGGTGAAGGTCGCGGCCAGCGGGGTCAACTTCATTGACGTATACTTTCGCACCGGCCTATATAAGGCCG
ACGCGCCGATAGCGATCGGCAGCGAAGCCGCGGGCACAGTGGAAGCTGTTGGCGCAGGTGTGACGGAGTTCAAGCCAGGC
GACCGGGTGGCGTACGCAATGGTACGCGGCTCCTACGCGGAATACGCGGTGGTGCCGGTTGGGATGCTGGTAAAGATTCC
CGACCACGTCGATTTTGTTACAGCCGCGGCCGCCATGTTGCAGGGCATGACGGCTCACTATCTGACGCACTCCACTTACC
TGCTCAAGGCCGGCCAAGCCTGCCTGGTGCATGCCGCCGCCGGCGGGACCGGTAGCTTGATCGTGCAGATGGCGAAAATG
CTCGGCGCGCGAGTTTTCGGCACCGTCTCCACCGAAGACAAGGCGCGGATCGCGCGCGAGGCGGGCGCCGACGAGACGAT
CCTCTACACGCAGCAGGAATTCGACGTGGAAGTGAAGCGCCTGACCCAAGGCCGCGGAGTGGACGTGGTGTACGACTCGG
TGGGCAAGACCACGTTCGAGAAGAGCCTTAACTCGCTTCGGCCGCGAGGGACGCTGGCGCTGTTCGGACAATCCAGCGGT
CCGGTGCCGCCGTTCGATCCGACAATTCTGAACGGGAAGGGTTCGCTGTACCTGACGCGCCCGAGCCTGGCACACTATAT
GATGACGCGCGACGAGTTGCTGTGGCGCGCCACGGATGTTCTGAAATGGATTGACAGCGGACAATTGAAATTAAGAATCG
ACCGCACCTACCCGCTGGCGGACGCGGCGTCGGCGCACCGCGATTTGGAAAGCCGCAAGACCGCGGGCAAGCTGGTACTC
GCGGTTTCGTGA

Upstream 100 bases:

>100_bases
GGACGCTGGTGCGAATGATTTCTTTTCCGTTCACTTTGTTGTATCTGATACTCTATGCAACGTCCGCGCACGCGCGGCGG
GCGCTCCGCAGAAGCTCATT

Downstream 100 bases:

>100_bases
TCCGATGACCCTGCAGGCCAAGCTGACGCTCGGCTCCGTGCTGCTGGCGACACTGATCGTGTCGTTCATCTCCGCGGTGG
ATCTGGGCAATCTGATGCAA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKAIQVLTPGGPESLHLLDAPVPRLGPDQALVKVAASGVNFIDVYFRTGLYKADAPIAIGSEAAGTVEAVGAGVTEFKPG
DRVAYAMVRGSYAEYAVVPVGMLVKIPDHVDFVTAAAAMLQGMTAHYLTHSTYLLKAGQACLVHAAAGGTGSLIVQMAKM
LGARVFGTVSTEDKARIAREAGADETILYTQQEFDVEVKRLTQGRGVDVVYDSVGKTTFEKSLNSLRPRGTLALFGQSSG
PVPPFDPTILNGKGSLYLTRPSLAHYMMTRDELLWRATDVLKWIDSGQLKLRIDRTYPLADAASAHRDLESRKTAGKLVL
AVS

Sequences:

>Translated_323_residues
MKAIQVLTPGGPESLHLLDAPVPRLGPDQALVKVAASGVNFIDVYFRTGLYKADAPIAIGSEAAGTVEAVGAGVTEFKPG
DRVAYAMVRGSYAEYAVVPVGMLVKIPDHVDFVTAAAAMLQGMTAHYLTHSTYLLKAGQACLVHAAAGGTGSLIVQMAKM
LGARVFGTVSTEDKARIAREAGADETILYTQQEFDVEVKRLTQGRGVDVVYDSVGKTTFEKSLNSLRPRGTLALFGQSSG
PVPPFDPTILNGKGSLYLTRPSLAHYMMTRDELLWRATDVLKWIDSGQLKLRIDRTYPLADAASAHRDLESRKTAGKLVL
AVS
>Mature_323_residues
MKAIQVLTPGGPESLHLLDAPVPRLGPDQALVKVAASGVNFIDVYFRTGLYKADAPIAIGSEAAGTVEAVGAGVTEFKPG
DRVAYAMVRGSYAEYAVVPVGMLVKIPDHVDFVTAAAAMLQGMTAHYLTHSTYLLKAGQACLVHAAAGGTGSLIVQMAKM
LGARVFGTVSTEDKARIAREAGADETILYTQQEFDVEVKRLTQGRGVDVVYDSVGKTTFEKSLNSLRPRGTLALFGQSSG
PVPPFDPTILNGKGSLYLTRPSLAHYMMTRDELLWRATDVLKWIDSGQLKLRIDRTYPLADAASAHRDLESRKTAGKLVL
AVS

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=328, Percent_Identity=32.3170731707317, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI13236495, Length=328, Percent_Identity=32.3170731707317, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI22538446, Length=336, Percent_Identity=30.952380952381, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI22538444, Length=336, Percent_Identity=30.952380952381, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI194239676, Length=328, Percent_Identity=31.4024390243902, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI18379349, Length=319, Percent_Identity=29.7805642633229, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI24308257, Length=244, Percent_Identity=33.6065573770492, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI28557745, Length=239, Percent_Identity=34.3096234309623, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI47519420, Length=345, Percent_Identity=24.9275362318841, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI197927207, Length=191, Percent_Identity=26.7015706806283, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1790485, Length=321, Percent_Identity=42.6791277258567, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1788073, Length=258, Percent_Identity=27.1317829457364, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17507255, Length=331, Percent_Identity=28.7009063444109, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI133901712, Length=315, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI133901710, Length=315, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562584, Length=352, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71987554, Length=186, Percent_Identity=30.1075268817204, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17556000, Length=188, Percent_Identity=28.7234042553192, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=325, Percent_Identity=39.3846153846154, Blast_Score=228, Evalue=9e-61,
Organism=Saccharomyces cerevisiae, GI6323729, Length=253, Percent_Identity=28.0632411067194, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=260, Percent_Identity=28.8461538461538, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323961, Length=256, Percent_Identity=28.515625, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319621, Length=253, Percent_Identity=26.8774703557312, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34506; Mature: 34506

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIQVLTPGGPESLHLLDAPVPRLGPDQALVKVAASGVNFIDVYFRTGLYKADAPIAIG
CCEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCEEECCCCEEEC
SEAAGTVEAVGAGVTEFKPGDRVAYAMVRGSYAEYAVVPVGMLVKIPDHVDFVTAAAAML
CCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEEEECCCCHHHHHHHHHHH
QGMTAHYLTHSTYLLKAGQACLVHAAAGGTGSLIVQMAKMLGARVFGTVSTEDKARIARE
HCCHHHHHHHCCCEEECCCEEEEEEECCCCHHHHHHHHHHHCHHEEEECCCCHHHHHHHH
AGADETILYTQQEFDVEVKRLTQGRGVDVVYDSVGKTTFEKSLNSLRPRGTLALFGQSSG
CCCCCEEEEECHHHCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCC
PVPPFDPTILNGKGSLYLTRPSLAHYMMTRDELLWRATDVLKWIDSGQLKLRIDRTYPLA
CCCCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
DAASAHRDLESRKTAGKLVLAVS
HHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MKAIQVLTPGGPESLHLLDAPVPRLGPDQALVKVAASGVNFIDVYFRTGLYKADAPIAIG
CCEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCEEECCCCEEEC
SEAAGTVEAVGAGVTEFKPGDRVAYAMVRGSYAEYAVVPVGMLVKIPDHVDFVTAAAAML
CCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEEEECCCCHHHHHHHHHHH
QGMTAHYLTHSTYLLKAGQACLVHAAAGGTGSLIVQMAKMLGARVFGTVSTEDKARIARE
HCCHHHHHHHCCCEEECCCEEEEEEECCCCHHHHHHHHHHHCHHEEEECCCCHHHHHHHH
AGADETILYTQQEFDVEVKRLTQGRGVDVVYDSVGKTTFEKSLNSLRPRGTLALFGQSSG
CCCCCEEEEECHHHCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCC
PVPPFDPTILNGKGSLYLTRPSLAHYMMTRDELLWRATDVLKWIDSGQLKLRIDRTYPLA
CCCCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
DAASAHRDLESRKTAGKLVLAVS
HHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]