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The map label for this gene is gap1 [H]

Identifier: 116626413

GI number: 116626413

Start: 9252172

End: 9253179

Strand: Direct

Name: gap1 [H]

Synonym: Acid_7375

Alternate gene names: 116626413

Gene position: 9252172-9253179 (Clockwise)

Preceding gene: 116626411

Following gene: 116626414

Centisome position: 92.84

GC content: 59.42

Gene sequence:

>1008_bases
ATGGCAATCAAAGTAGGAATTAATGGCTTCGGCCGGATCGGCCGTAATGTCGTTCGTGCAGGTTTGCATAATAGCGACGT
CGAATTCGTTGCGGTCAATGATTTGACCGACACGGCGACATTAGCCCACCTCTTGAAGTACGATTCGGTGCTCGGCACCC
TTCCCGAAACGGTCACCCACGACGCGACTTCGATCACTGTCGGCGGCAAAACCATTAAAGTCTTCGCCACCAAGGACCCC
GCGGAACTCGATTGGGCCAGCGTCGGCGCCCAGATCGTCATCGAATCCACCGGTCGTTTCACGGACGGCAAGGACGCCGC
CAAGCACATGCGCGGCACCGTCAAGAAAGTCATTATTTCGGCTCCCGCAAAGAATGAGGATGTGACCCTCGTGCTCGGCG
TCAACGATGCCGCTTACGACGCGAAGAAGCACAACATCATCTCTAACGCATCCTGCACCACCAACTGCCTGGCCCCCGTG
GTCAAGGTCCTCAATGAAAAGTTCGGCGTGGAAAAGGGGTCGATGACCACCATCCACAGCTACACCAACGATCAGAACGT
CCTCGATTTCCCGCACAAAGACCTGCGCCGCGCCCGCGCCGCCGCGCTCAACATGATCCCGACCACCACCGGCGCCGCCA
AGGCGATCGGCCTCGTGCTCCCCGAACTCAAGGGCAAACTCGATGGCTACTCCATGCGCGTCCCCACACCGGACGTCTCC
GTGGTCGATTTCGTCTGCATCCTGAAAAAGCCGTCCACCACCGAAGCCGTCAACGCCGCCCTTAAGGCCGCGTCCGAAGG
CGAACTCAAGGGCATCCTGGGCTACACCGAGGATCCCGTGGTCTCCACCGACATGCTGCGCAATCCCAACAGCAGCATCG
TGGACGCACAGTTGACCAAGGTCCTGGATGGCAACCTCCTCAAAGTCGTCGCCTGGTACGACAACGAATGGGGCTACTCC
AGCCGCGTCGTTGACCTCGTCGGCTTCCTCGCCGCCAAAGGCCTGTAA

Upstream 100 bases:

>100_bases
AGTTTAAGAATTTAAACTCCGAATCCTAAGGTTGCCCGCGATACCCCCCTCCTGTTATCCTAAATCTTAATCCGATCCCT
CATTTCGCACAGGAGAAACA

Downstream 100 bases:

>100_bases
TTTCCGCATTCCCCAGGATTGCTGCCCCTCTCTTTACCTGCCATAGCTCTCGCGCAGACACTGTGGGGCAGCCAATCCTG
GCTGCAGCCGCCTTTCAGGC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH 1 [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAIKVGINGFGRIGRNVVRAGLHNSDVEFVAVNDLTDTATLAHLLKYDSVLGTLPETVTHDATSITVGGKTIKVFATKDP
AELDWASVGAQIVIESTGRFTDGKDAAKHMRGTVKKVIISAPAKNEDVTLVLGVNDAAYDAKKHNIISNASCTTNCLAPV
VKVLNEKFGVEKGSMTTIHSYTNDQNVLDFPHKDLRRARAAALNMIPTTTGAAKAIGLVLPELKGKLDGYSMRVPTPDVS
VVDFVCILKKPSTTEAVNAALKAASEGELKGILGYTEDPVVSTDMLRNPNSSIVDAQLTKVLDGNLLKVVAWYDNEWGYS
SRVVDLVGFLAAKGL

Sequences:

>Translated_335_residues
MAIKVGINGFGRIGRNVVRAGLHNSDVEFVAVNDLTDTATLAHLLKYDSVLGTLPETVTHDATSITVGGKTIKVFATKDP
AELDWASVGAQIVIESTGRFTDGKDAAKHMRGTVKKVIISAPAKNEDVTLVLGVNDAAYDAKKHNIISNASCTTNCLAPV
VKVLNEKFGVEKGSMTTIHSYTNDQNVLDFPHKDLRRARAAALNMIPTTTGAAKAIGLVLPELKGKLDGYSMRVPTPDVS
VVDFVCILKKPSTTEAVNAALKAASEGELKGILGYTEDPVVSTDMLRNPNSSIVDAQLTKVLDGNLLKVVAWYDNEWGYS
SRVVDLVGFLAAKGL
>Mature_334_residues
AIKVGINGFGRIGRNVVRAGLHNSDVEFVAVNDLTDTATLAHLLKYDSVLGTLPETVTHDATSITVGGKTIKVFATKDPA
ELDWASVGAQIVIESTGRFTDGKDAAKHMRGTVKKVIISAPAKNEDVTLVLGVNDAAYDAKKHNIISNASCTTNCLAPVV
KVLNEKFGVEKGSMTTIHSYTNDQNVLDFPHKDLRRARAAALNMIPTTTGAAKAIGLVLPELKGKLDGYSMRVPTPDVSV
VDFVCILKKPSTTEAVNAALKAASEGELKGILGYTEDPVVSTDMLRNPNSSIVDAQLTKVLDGNLLKVVAWYDNEWGYSS
RVVDLVGFLAAKGL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=333, Percent_Identity=47.4474474474475, Blast_Score=310, Evalue=8e-85,
Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=47.4474474474475, Blast_Score=309, Evalue=2e-84,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=51.2048192771084, Blast_Score=330, Evalue=9e-92,
Organism=Escherichia coli, GI1789295, Length=330, Percent_Identity=41.8181818181818, Blast_Score=273, Evalue=8e-75,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=51.9287833827893, Blast_Score=334, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=51.9287833827893, Blast_Score=333, Evalue=7e-92,
Organism=Caenorhabditis elegans, GI32566163, Length=336, Percent_Identity=50.5952380952381, Blast_Score=323, Evalue=7e-89,
Organism=Caenorhabditis elegans, GI17568413, Length=336, Percent_Identity=50.5952380952381, Blast_Score=323, Evalue=9e-89,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=51.3595166163142, Blast_Score=320, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=49.5468277945619, Blast_Score=319, Evalue=5e-88,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=50.7552870090634, Blast_Score=316, Evalue=4e-87,
Organism=Drosophila melanogaster, GI85725000, Length=332, Percent_Identity=48.1927710843374, Blast_Score=304, Evalue=7e-83,
Organism=Drosophila melanogaster, GI22023983, Length=332, Percent_Identity=48.1927710843374, Blast_Score=304, Evalue=7e-83,
Organism=Drosophila melanogaster, GI17933600, Length=332, Percent_Identity=47.5903614457831, Blast_Score=301, Evalue=4e-82,
Organism=Drosophila melanogaster, GI18110149, Length=332, Percent_Identity=47.5903614457831, Blast_Score=301, Evalue=4e-82,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=45.8461538461538, Blast_Score=289, Evalue=1e-78,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35703; Mature: 35572

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKVGINGFGRIGRNVVRAGLHNSDVEFVAVNDLTDTATLAHLLKYDSVLGTLPETVTH
CEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCC
DATSITVGGKTIKVFATKDPAELDWASVGAQIVIESTGRFTDGKDAAKHMRGTVKKVIIS
CCEEEEECCEEEEEEECCCCCCCCHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHEEE
APAKNEDVTLVLGVNDAAYDAKKHNIISNASCTTNCLAPVVKVLNEKFGVEKGSMTTIHS
CCCCCCCEEEEEECCHHHHCHHHCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
YTNDQNVLDFPHKDLRRARAAALNMIPTTTGAAKAIGLVLPELKGKLDGYSMRVPTPDVS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHH
VVDFVCILKKPSTTEAVNAALKAASEGELKGILGYTEDPVVSTDMLRNPNSSIVDAQLTK
HHHHEEEECCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHCCCCCCHHHHHHHH
VLDGNLLKVVAWYDNEWGYSSRVVDLVGFLAAKGL
HHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIKVGINGFGRIGRNVVRAGLHNSDVEFVAVNDLTDTATLAHLLKYDSVLGTLPETVTH
EEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCC
DATSITVGGKTIKVFATKDPAELDWASVGAQIVIESTGRFTDGKDAAKHMRGTVKKVIIS
CCEEEEECCEEEEEEECCCCCCCCHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHEEE
APAKNEDVTLVLGVNDAAYDAKKHNIISNASCTTNCLAPVVKVLNEKFGVEKGSMTTIHS
CCCCCCCEEEEEECCHHHHCHHHCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
YTNDQNVLDFPHKDLRRARAAALNMIPTTTGAAKAIGLVLPELKGKLDGYSMRVPTPDVS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHH
VVDFVCILKKPSTTEAVNAALKAASEGELKGILGYTEDPVVSTDMLRNPNSSIVDAQLTK
HHHHEEEECCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHCCCCCCHHHHHHHH
VLDGNLLKVVAWYDNEWGYSSRVVDLVGFLAAKGL
HHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA