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The map label for this gene is uvrC [H]

Identifier: 116626337

GI number: 116626337

Start: 9159201

End: 9160313

Strand: Direct

Name: uvrC [H]

Synonym: Acid_7297

Alternate gene names: 116626337

Gene position: 9159201-9160313 (Clockwise)

Preceding gene: 116626336

Following gene: 116626338

Centisome position: 91.91

GC content: 62.53

Gene sequence:

>1113_bases
ATGATTGCGCTCGAAATCGGCGGCGACCTGGCTGCAATGGATGCGGCGATCGAGGCGCTGCCCAATCAGCCGGCGGTCTT
CCTGCTGTGGCCTGCTGAGGGCGAGCCGTTCCTTTCGCGGACTGGTCTGTTGCGGCGGCGATTGCTGCGACTGTTGAAGG
AGCGGGAGCGGCCTTCGCGGCTGCTGAATTTGCGGCACACGGTGGCGCGCATCGAATACCAGTTGACGGGGTCGGCATTC
GAATCGTCAGTGGTCTTCTACGAAGCGGCGCGGCGGCATTTTCCCGAGCGGTACCTGCAACTGATGAAGCTGCGCATGCC
GCCGTACCTGAAGGTGGTGCTGGGCAATGAATTTCCGCGCAGCCAGATCACGACGCAATTGACGCGGAGCGCCGGACTGT
ACTTCGGGCCTTTCCGCTCGCGCGCGTCCGCGGAACGTTTTGAAGGACAGTTTCTGGACCTCTTCCAGATGCGGCGATGC
CAGGAAGACCTGATCCCGACGCCCGAACATCCAGGCTGCATTTACGGCGAGATGGCGATGTGTCTGCGGCCGTGCCAGCA
GGTGGTCGGGCGCGAGGAGTACGGGCACGAAGTGGATCGCGTGGTGGAGTTTCTGCGCACGGACGGGCGCAGCCTGCTGG
AATCGATCGGGCATTCGCGCGATCGTTTGAGCGAAGAGATGATGTTCGAAGAAGCGGCGCGGCAGCACAAGCGATTCGAA
AAAGTGCAGGAAGTACTGCGGCTGCGCGACGAACTGGTACGCGAGGTGGACGGGCTAAATGGTGTCGCGATCACGCCATC
GCTGGCGCACGACGCAGTGGAGATGTGGTTCGTGCGCGAGGGAACATGGTGCCGGCCGGAGAGGTTCGGGTTCGAGGTGC
AGGAGGGCAAGCCGGTCTCGTTGGATCGGAAGCTGCGCGATCTGCTGGCAGGTGTTCAGCCGCGGAAGCTGTCGGTGCGT
GAGCGGCAGGAGTACCTGGCGCTGCTGGCTCGCTGGTATTACTCCACGTGGCGCGAAGGCGAATGGCTGAATTTCGAGAG
CTACGACGAGATTCCGTATCGCAAGCTGGTGAACGCAGTTTCGCGGGTGGCGCGGCGAGAGAGCAGCTTATAA

Upstream 100 bases:

>100_bases
CGCTGGTGGGAATGTCGCGGCGCGAGCACGTGCTGGAGAATCTGGGTGTGGCGCGGGTGGCGCCGATACCGCGCGAAGAG
TACGTCCGGTTGTATCAGTA

Downstream 100 bases:

>100_bases
TAGGTTCCTTAGACTAAGCTGGAGAGCGACGATGAAAGAATGGGGCTTCGCACAAAACCACCCGAACGAAGAGCTGGCGC
AGTTACACCTGTTCTCGATG

Product: UvrB/UvrC protein

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MIALEIGGDLAAMDAAIEALPNQPAVFLLWPAEGEPFLSRTGLLRRRLLRLLKERERPSRLLNLRHTVARIEYQLTGSAF
ESSVVFYEAARRHFPERYLQLMKLRMPPYLKVVLGNEFPRSQITTQLTRSAGLYFGPFRSRASAERFEGQFLDLFQMRRC
QEDLIPTPEHPGCIYGEMAMCLRPCQQVVGREEYGHEVDRVVEFLRTDGRSLLESIGHSRDRLSEEMMFEEAARQHKRFE
KVQEVLRLRDELVREVDGLNGVAITPSLAHDAVEMWFVREGTWCRPERFGFEVQEGKPVSLDRKLRDLLAGVQPRKLSVR
ERQEYLALLARWYYSTWREGEWLNFESYDEIPYRKLVNAVSRVARRESSL

Sequences:

>Translated_370_residues
MIALEIGGDLAAMDAAIEALPNQPAVFLLWPAEGEPFLSRTGLLRRRLLRLLKERERPSRLLNLRHTVARIEYQLTGSAF
ESSVVFYEAARRHFPERYLQLMKLRMPPYLKVVLGNEFPRSQITTQLTRSAGLYFGPFRSRASAERFEGQFLDLFQMRRC
QEDLIPTPEHPGCIYGEMAMCLRPCQQVVGREEYGHEVDRVVEFLRTDGRSLLESIGHSRDRLSEEMMFEEAARQHKRFE
KVQEVLRLRDELVREVDGLNGVAITPSLAHDAVEMWFVREGTWCRPERFGFEVQEGKPVSLDRKLRDLLAGVQPRKLSVR
ERQEYLALLARWYYSTWREGEWLNFESYDEIPYRKLVNAVSRVARRESSL
>Mature_370_residues
MIALEIGGDLAAMDAAIEALPNQPAVFLLWPAEGEPFLSRTGLLRRRLLRLLKERERPSRLLNLRHTVARIEYQLTGSAF
ESSVVFYEAARRHFPERYLQLMKLRMPPYLKVVLGNEFPRSQITTQLTRSAGLYFGPFRSRASAERFEGQFLDLFQMRRC
QEDLIPTPEHPGCIYGEMAMCLRPCQQVVGREEYGHEVDRVVEFLRTDGRSLLESIGHSRDRLSEEMMFEEAARQHKRFE
KVQEVLRLRDELVREVDGLNGVAITPSLAHDAVEMWFVREGTWCRPERFGFEVQEGKPVSLDRKLRDLLAGVQPRKLSVR
ERQEYLALLARWYYSTWREGEWLNFESYDEIPYRKLVNAVSRVARRESSL

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=269, Percent_Identity=21.5613382899628, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 43239; Mature: 43239

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALEIGGDLAAMDAAIEALPNQPAVFLLWPAEGEPFLSRTGLLRRRLLRLLKERERPSR
CEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
LLNLRHTVARIEYQLTGSAFESSVVFYEAARRHFPERYLQLMKLRMPPYLKVVLGNEFPR
HHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEECCCCCH
SQITTQLTRSAGLYFGPFRSRASAERFEGQFLDLFQMRRCQEDLIPTPEHPGCIYGEMAM
HHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
CLRPCQQVVGREEYGHEVDRVVEFLRTDGRSLLESIGHSRDRLSEEMMFEEAARQHKRFE
HHHHHHHHHCCHHCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KVQEVLRLRDELVREVDGLNGVAITPSLAHDAVEMWFVREGTWCRPERFGFEVQEGKPVS
HHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCCCCCHHHCCCEECCCCCCC
LDRKLRDLLAGVQPRKLSVRERQEYLALLARWYYSTWREGEWLNFESYDEIPYRKLVNAV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
SRVARRESSL
HHHHHHHCCC
>Mature Secondary Structure
MIALEIGGDLAAMDAAIEALPNQPAVFLLWPAEGEPFLSRTGLLRRRLLRLLKERERPSR
CEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
LLNLRHTVARIEYQLTGSAFESSVVFYEAARRHFPERYLQLMKLRMPPYLKVVLGNEFPR
HHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEECCCCCH
SQITTQLTRSAGLYFGPFRSRASAERFEGQFLDLFQMRRCQEDLIPTPEHPGCIYGEMAM
HHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
CLRPCQQVVGREEYGHEVDRVVEFLRTDGRSLLESIGHSRDRLSEEMMFEEAARQHKRFE
HHHHHHHHHCCHHCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KVQEVLRLRDELVREVDGLNGVAITPSLAHDAVEMWFVREGTWCRPERFGFEVQEGKPVS
HHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCCCCCHHHCCCEECCCCCCC
LDRKLRDLLAGVQPRKLSVRERQEYLALLARWYYSTWREGEWLNFESYDEIPYRKLVNAV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
SRVARRESSL
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA