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The map label for this gene is yeaD [H]

Identifier: 116626299

GI number: 116626299

Start: 9110321

End: 9111178

Strand: Direct

Name: yeaD [H]

Synonym: Acid_7259

Alternate gene names: 116626299

Gene position: 9110321-9111178 (Clockwise)

Preceding gene: 116626298

Following gene: 116626304

Centisome position: 91.42

GC content: 65.5

Gene sequence:

>858_bases
ATGGGCGCCGTCGAAATCCCCGGGGCCTTACAACTCGAGAATGGCGATGATGGCCTCACCCGCGTCCTCATCGACACACC
CCAGGCCGAGGCCGAGATCTTCCTCCACGGCGCGCACATCACGCGCTGGGTTCCAGCCGGAAAACGCCCGGTACTCTTCA
CCAGCTCCCGAAGCCTGTACGCGCCCGGTAAGCCCATCCGCGGCGGCGTCCCGCTGGTCTTTCCCTGGTTCGGCCCGCGC
GGCGGCGGCCTGCCCGGCCCCATGCACGGCTACGCCCGCATCAGCGAGTGGACGCTCCATGCCACCAGCATGCGCGACGA
TGGCGCGGTGGAACTGGTCTTCACGCTCCCACGAGTGGACGCTTTCCGTCTGGCCTATCGCGTCGCCGTCGGCGCTAGGC
TCGAAATGGAACTCGACGTCCGCAATACATCGGCCGAAGAGCTCTGCTTCGAGGAGGCCTTCCATACCTACTTCGCCGTC
GGCGACATCCACCAGGTCTCCATCTCCGGAGTCGAAGGCACTGAATACATCGACAAAGCCGACGGCTTCCAGCGCAAACG
CCACCCCGCCGAGCCCATCCGGATCGATCGGTACACCGACCAGGTCCACGTCAACACCACCGGCGTCTGCGTGATCGATG
ACGCAGCCTGGGCCCGCCGCATCGTAATCGCCAAAAGCGGGTCCGCCACCACGGTCGTGTGGAATCCCTGGTCCGACAAG
ACTCCCGGCATGCCCGACATGGCGCCCGAAGACTGGCGCGAAATGGTCTGCGTCGAAACCGCCAATGCCGGCGAAAACGG
CATCCGCCTCGGCCCCGGCGCCAGTCACATAATGCGCGCCACCATGAAAGTCGAGTAG

Upstream 100 bases:

>100_bases
ACATTCCGATCCACATCATGCCCAACGGCGATACCGCCGGAGCACGCGGAGCCGCCATCGAATCGCTCCAACTGGCGCGG
CAAGCGGGGTTGCTGTAGCC

Downstream 100 bases:

>100_bases
TACAGTTCTCCGGGCCTGTCTCGCTATTACCCTGTCATTCGCAATTCCAGCGAGACCACCGACCGCGCCGGCACCGCGAC
CTCCGCCCCATCCGCGCCCA

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MGAVEIPGALQLENGDDGLTRVLIDTPQAEAEIFLHGAHITRWVPAGKRPVLFTSSRSLYAPGKPIRGGVPLVFPWFGPR
GGGLPGPMHGYARISEWTLHATSMRDDGAVELVFTLPRVDAFRLAYRVAVGARLEMELDVRNTSAEELCFEEAFHTYFAV
GDIHQVSISGVEGTEYIDKADGFQRKRHPAEPIRIDRYTDQVHVNTTGVCVIDDAAWARRIVIAKSGSATTVVWNPWSDK
TPGMPDMAPEDWREMVCVETANAGENGIRLGPGASHIMRATMKVE

Sequences:

>Translated_285_residues
MGAVEIPGALQLENGDDGLTRVLIDTPQAEAEIFLHGAHITRWVPAGKRPVLFTSSRSLYAPGKPIRGGVPLVFPWFGPR
GGGLPGPMHGYARISEWTLHATSMRDDGAVELVFTLPRVDAFRLAYRVAVGARLEMELDVRNTSAEELCFEEAFHTYFAV
GDIHQVSISGVEGTEYIDKADGFQRKRHPAEPIRIDRYTDQVHVNTTGVCVIDDAAWARRIVIAKSGSATTVVWNPWSDK
TPGMPDMAPEDWREMVCVETANAGENGIRLGPGASHIMRATMKVE
>Mature_284_residues
GAVEIPGALQLENGDDGLTRVLIDTPQAEAEIFLHGAHITRWVPAGKRPVLFTSSRSLYAPGKPIRGGVPLVFPWFGPRG
GGLPGPMHGYARISEWTLHATSMRDDGAVELVFTLPRVDAFRLAYRVAVGARLEMELDVRNTSAEELCFEEAFHTYFAVG
DIHQVSISGVEGTEYIDKADGFQRKRHPAEPIRIDRYTDQVHVNTTGVCVIDDAAWARRIVIAKSGSATTVVWNPWSDKT
PGMPDMAPEDWREMVCVETANAGENGIRLGPGASHIMRATMKVE

Specific function: Unknown

COG id: COG0676

COG function: function code G; Uncharacterized enzymes related to aldose 1-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=273, Percent_Identity=35.1648351648352, Blast_Score=142, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6323746, Length=262, Percent_Identity=27.8625954198473, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19921284, Length=266, Percent_Identity=32.3308270676692, Blast_Score=130, Evalue=7e-31,
Organism=Drosophila melanogaster, GI28574481, Length=169, Percent_Identity=29.585798816568, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 31276; Mature: 31145

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAVEIPGALQLENGDDGLTRVLIDTPQAEAEIFLHGAHITRWVPAGKRPVLFTSSRSLY
CCCEECCCEEEEECCCCCEEEEEEECCCCCEEEEEECCEEEEECCCCCCCEEEECCCCEE
APGKPIRGGVPLVFPWFGPRGGGLPGPMHGYARISEWTLHATSMRDDGAVELVFTLPRVD
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEEECCCCH
AFRLAYRVAVGARLEMELDVRNTSAEELCFEEAFHTYFAVGDIHQVSISGVEGTEYIDKA
HHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHEEEECCEEEEEEECCCCCHHHHHC
DGFQRKRHPAEPIRIDRYTDQVHVNTTGVCVIDDAAWARRIVIAKSGSATTVVWNPWSDK
CCCHHHCCCCCCEEEEEECCEEEECCCEEEEEECCHHEEEEEEEECCCEEEEEECCCCCC
TPGMPDMAPEDWREMVCVETANAGENGIRLGPGASHIMRATMKVE
CCCCCCCCCHHHHEEEEEEECCCCCCCEEECCCHHHHEEEEEECC
>Mature Secondary Structure 
GAVEIPGALQLENGDDGLTRVLIDTPQAEAEIFLHGAHITRWVPAGKRPVLFTSSRSLY
CCEECCCEEEEECCCCCEEEEEEECCCCCEEEEEECCEEEEECCCCCCCEEEECCCCEE
APGKPIRGGVPLVFPWFGPRGGGLPGPMHGYARISEWTLHATSMRDDGAVELVFTLPRVD
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEEECCCCH
AFRLAYRVAVGARLEMELDVRNTSAEELCFEEAFHTYFAVGDIHQVSISGVEGTEYIDKA
HHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHEEEECCEEEEEEECCCCCHHHHHC
DGFQRKRHPAEPIRIDRYTDQVHVNTTGVCVIDDAAWARRIVIAKSGSATTVVWNPWSDK
CCCHHHCCCCCCEEEEEECCEEEECCCEEEEEECCHHEEEEEEEECCCEEEEEECCCCCC
TPGMPDMAPEDWREMVCVETANAGENGIRLGPGASHIMRATMKVE
CCCCCCCCCHHHHEEEEEEECCCCCCCEEECCCHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]