The gene/protein map for NC_008536 is currently unavailable.
Definition Candidatus Solibacter usitatus Ellin6076 chromosome, complete genome.
Accession NC_008536
Length 9,965,640

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The map label for this gene is gdhII [H]

Identifier: 116626237

GI number: 116626237

Start: 9039657

End: 9040481

Strand: Direct

Name: gdhII [H]

Synonym: Acid_7197

Alternate gene names: 116626237

Gene position: 9039657-9040481 (Clockwise)

Preceding gene: 116626236

Following gene: 116626238

Centisome position: 90.71

GC content: 61.94

Gene sequence:

>825_bases
TTGACCACTATAAAAGGTAAGAGCGTTTTGATTACCGGGGCGGGCCGCGGCATTGGCAAACGCCTCGCAATGGGATTTGC
CGCCGAGGGCGCCCGGGTGGGCCTGCTGGCGCGCAGCCAGGCGGAAATCGAACTGGCAAAACTGGAAATCGAACAGGCCG
GCGGCTCCGCCATGTGTCTGCGCGCCGATGTTCGGCACCCCGAGGATCTCGCGCATGCCGTGGAGCGCTTGCGCGCCAAG
TTCGGAAGCTTGGATGTTCTGATCGCCGCCGCCGCGGTGCAAGGCCCGATCGGACCGTTCCTGGCCAGCAAGCCCAAGGC
CTGGAACGATGCGATCGAAACCAACCTGATCGGCGTCGCCAATTCCTGCCGGGTGGCGTTGCCGCCAATGATCGAAAAAC
GCTCCGGCAAGATCATCCTGATCGCCGGCGGCGGCTCCGCGTACTCGCGTCCCAACTTTACGGCCTATGCGGCTTCGAAA
TCCGCCGTGGTTCGCTTCGGCGAGACCCTTGCCGATGAAGTGCGCGACCACAATGTACAGGTCAACACGATCGCTCCCGG
CGCCGCCTACTCAACCATGACCGACGAGATTATCAATGCCGGCGAAGAGCGGGCCGGCCGAAAAGAGATCGAGGACGCCG
AAAAGGTCCGCGTCACGGGCGGCATTCCCGCCGAAAAACAGATCGCTCTCGCGCTCTTTCTCGCCAGCGAAAAGAGCAAC
CACATCAGCGGCAAACTCATCCACGTCAACGACGATTGGAAACGCTTCGAGCAGGACAACATGAAGGCCGAGCTCTACAC
GCTGCGCCGTGTGCAGAAGGTCTAG

Upstream 100 bases:

>100_bases
GGCTTCCCCAAAGCCGGAGCCTACCGCGTCTTCGTGCAGATGAAGCGCGGCGGCCAAATCCTGACCGGGGCCTTCACCAC
GACTGTGGAGAATTGATCTT

Downstream 100 bases:

>100_bases
CAGAGGTCTCTCCTTGTTGAGAGAGAGTAACGCAAAGAACTCCAAAGACGGAAGGTGCTCGGAAAACCCGCGGCTGGACA
AGCGGCATCGCAGGCACGGA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: GLCDH-II [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTTIKGKSVLITGAGRGIGKRLAMGFAAEGARVGLLARSQAEIELAKLEIEQAGGSAMCLRADVRHPEDLAHAVERLRAK
FGSLDVLIAAAAVQGPIGPFLASKPKAWNDAIETNLIGVANSCRVALPPMIEKRSGKIILIAGGGSAYSRPNFTAYAASK
SAVVRFGETLADEVRDHNVQVNTIAPGAAYSTMTDEIINAGEERAGRKEIEDAEKVRVTGGIPAEKQIALALFLASEKSN
HISGKLIHVNDDWKRFEQDNMKAELYTLRRVQKV

Sequences:

>Translated_274_residues
MTTIKGKSVLITGAGRGIGKRLAMGFAAEGARVGLLARSQAEIELAKLEIEQAGGSAMCLRADVRHPEDLAHAVERLRAK
FGSLDVLIAAAAVQGPIGPFLASKPKAWNDAIETNLIGVANSCRVALPPMIEKRSGKIILIAGGGSAYSRPNFTAYAASK
SAVVRFGETLADEVRDHNVQVNTIAPGAAYSTMTDEIINAGEERAGRKEIEDAEKVRVTGGIPAEKQIALALFLASEKSN
HISGKLIHVNDDWKRFEQDNMKAELYTLRRVQKV
>Mature_273_residues
TTIKGKSVLITGAGRGIGKRLAMGFAAEGARVGLLARSQAEIELAKLEIEQAGGSAMCLRADVRHPEDLAHAVERLRAKF
GSLDVLIAAAAVQGPIGPFLASKPKAWNDAIETNLIGVANSCRVALPPMIEKRSGKIILIAGGGSAYSRPNFTAYAASKS
AVVRFGETLADEVRDHNVQVNTIAPGAAYSTMTDEIINAGEERAGRKEIEDAEKVRVTGGIPAEKQIALALFLASEKSNH
ISGKLIHVNDDWKRFEQDNMKAELYTLRRVQKV

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=191, Percent_Identity=28.7958115183246, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=27.5303643724696, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4503817, Length=188, Percent_Identity=27.6595744680851, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI20149619, Length=218, Percent_Identity=28.4403669724771, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=26.953125, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI142976729, Length=172, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4557649, Length=195, Percent_Identity=27.6923076923077, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=25, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI157739938, Length=195, Percent_Identity=30.2564102564103, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=28.021978021978, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=24, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI223718074, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI210032110, Length=173, Percent_Identity=25.4335260115607, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI33667109, Length=178, Percent_Identity=27.5280898876405, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=26.5625, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=32.4, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=31.2252964426877, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=34.1176470588235, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=27.9527559055118, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=29.5719844357977, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=31.7269076305221, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=26.2295081967213, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=27.4809160305344, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=27.0491803278689, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787820, Length=205, Percent_Identity=25.3658536585366, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=23.265306122449, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=27.843137254902, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=246, Percent_Identity=25.609756097561, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=28.4552845528455, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=198, Percent_Identity=29.2929292929293, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=29.1497975708502, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=260, Percent_Identity=27.6923076923077, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=195, Percent_Identity=30.2564102564103, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=27.0833333333333, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=206, Percent_Identity=29.126213592233, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=241, Percent_Identity=23.6514522821577, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=195, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=26.6409266409266, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=200, Percent_Identity=27.5, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=198, Percent_Identity=25.2525252525253, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=232, Percent_Identity=29.7413793103448, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=196, Percent_Identity=29.5918367346939, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=26.3358778625954, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=27.3684210526316, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=27.8195488721804, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=213, Percent_Identity=29.1079812206573, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=205, Percent_Identity=26.3414634146341, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=27.2388059701493, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=280, Percent_Identity=27.1428571428571, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=202, Percent_Identity=25.7425742574257, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=26.7676767676768, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=26.7676767676768, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=205, Percent_Identity=32.1951219512195, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322227, Length=259, Percent_Identity=24.7104247104247, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=223, Percent_Identity=25.5605381165919, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=30.7291666666667, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=193, Percent_Identity=26.9430051813472, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=24.2914979757085, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640492, Length=195, Percent_Identity=27.1794871794872, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=28.5140562248996, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24584744, Length=204, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574402, Length=204, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358495, Length=190, Percent_Identity=30.5263157894737, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=27.3809523809524, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI18859837, Length=202, Percent_Identity=29.2079207920792, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24644339, Length=242, Percent_Identity=28.099173553719, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221331218, Length=206, Percent_Identity=26.6990291262136, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24665243, Length=206, Percent_Identity=26.6990291262136, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI161076933, Length=194, Percent_Identity=27.319587628866, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=27.6041666666667, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21357673, Length=211, Percent_Identity=28.9099526066351, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221331216, Length=207, Percent_Identity=26.5700483091787, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24665247, Length=207, Percent_Identity=26.5700483091787, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356301, Length=189, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 29326; Mature: 29195

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTTIKGKSVLITGAGRGIGKRLAMGFAAEGARVGLLARSQAEIELAKLEIEQAGGSAMCL
CCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEEECCCCCEEEE
RADVRHPEDLAHAVERLRAKFGSLDVLIAAAAVQGPIGPFLASKPKAWNDAIETNLIGVA
EECCCCHHHHHHHHHHHHHHHCCHHHEEEHHHHCCCCCHHHCCCCCCCHHHHHHCEEEEC
NSCRVALPPMIEKRSGKIILIAGGGSAYSRPNFTAYAASKSAVVRFGETLADEVRDHNVQ
CCCEEECCCCHHCCCCCEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCEE
VNTIAPGAAYSTMTDEIINAGEERAGRKEIEDAEKVRVTGGIPAEKQIALALFLASEKSN
EEEECCCCHHHHHHHHHHCCCHHHCCHHHCCCCCEEEEECCCCCHHHEEEEEEEECCCCC
HISGKLIHVNDDWKRFEQDNMKAELYTLRRVQKV
CCCEEEEEECCHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TTIKGKSVLITGAGRGIGKRLAMGFAAEGARVGLLARSQAEIELAKLEIEQAGGSAMCL
CCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEEECCCCCEEEE
RADVRHPEDLAHAVERLRAKFGSLDVLIAAAAVQGPIGPFLASKPKAWNDAIETNLIGVA
EECCCCHHHHHHHHHHHHHHHCCHHHEEEHHHHCCCCCHHHCCCCCCCHHHHHHCEEEEC
NSCRVALPPMIEKRSGKIILIAGGGSAYSRPNFTAYAASKSAVVRFGETLADEVRDHNVQ
CCCEEECCCCHHCCCCCEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCEE
VNTIAPGAAYSTMTDEIINAGEERAGRKEIEDAEKVRVTGGIPAEKQIALALFLASEKSN
EEEECCCCHHHHHHHHHHCCCHHHCCHHHCCCCCEEEEECCCCCHHHEEEEEEEECCCCC
HISGKLIHVNDDWKRFEQDNMKAELYTLRRVQKV
CCCEEEEEECCHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA