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The map label for this gene is ywlC [H]

Identifier: 116626156

GI number: 116626156

Start: 8934639

End: 8935277

Strand: Direct

Name: ywlC [H]

Synonym: Acid_7116

Alternate gene names: 116626156

Gene position: 8934639-8935277 (Clockwise)

Preceding gene: 116626155

Following gene: 116626157

Centisome position: 89.65

GC content: 63.38

Gene sequence:

>639_bases
ATGGCAACCGACCTGGTCGAAATCAATACCGAAGATCCCCAGCCGGAAGCGCTGGAGAGGGCCGCCGCCGCTGTGCGCCG
CGGCAAGGTGGTGGCCATTCCCACCGATGCCCTGTACACGCTGGTGGCGGATCCCTACAACCTGCGCGCCGTCACCGGAG
TGTTCCAGGCCAAAGGGCGCGAGCCGCACCGGGCGCTGCCGATATTGATTCGCGACAGCATGATGGCGGAAGAACTGGCC
AGCGAGTTGAACAACCGCTTCTTCATCTTGGCGCGCCGTTTTTGGCCTGGACCCTTGACCGTCATCGTGCCGGCCGCGGC
CAAGATTCCCCTGAAGGTCACAGGCAACACCGGCCGCCTGGCATTGCGTCACGCGCGCTCCCCGGTGGCGGATAAGTTGA
TCGCGCTGCTCAACCAGCCGCTGATTTCCACCAGCGCCAACATCTCGGGACATCCCACCTGCCACAGCGGCATCGATGTG
TTCGGAATGATGGATGGCCGCGTGGACCTGGTTCTGGACGGCGGGACCTGCGTGGGAGAGGGCTCCACCACGGTGGATAT
TACCGAGCCGTACTGGCGCATGATCAAAGAAGGAGCGATCTCCGAAAAGGAAATCGCGGAGTGCCTGAAGCCGGCGTGA

Upstream 100 bases:

>100_bases
AGGGCGCGCAACTCAGCGCGCCTTTCGGCCGCTATCAGATGGCGATCGACGTTGCCGATGCCATCGAGTCCCGCTAAGAT
CGGAACACAAGATCCGAAAC

Downstream 100 bases:

>100_bases
AGTATCTGCTCATCGCGCTCGGAGGAGGCACCGGCTCTCTGGCACGCTATCTCTTAGGAACCGCGATTACCAGCCGGGTG
GGAGCCCGCTTTCCGATCGG

Product: translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MATDLVEINTEDPQPEALERAAAAVRRGKVVAIPTDALYTLVADPYNLRAVTGVFQAKGREPHRALPILIRDSMMAEELA
SELNNRFFILARRFWPGPLTVIVPAAAKIPLKVTGNTGRLALRHARSPVADKLIALLNQPLISTSANISGHPTCHSGIDV
FGMMDGRVDLVLDGGTCVGEGSTTVDITEPYWRMIKEGAISEKEIAECLKPA

Sequences:

>Translated_212_residues
MATDLVEINTEDPQPEALERAAAAVRRGKVVAIPTDALYTLVADPYNLRAVTGVFQAKGREPHRALPILIRDSMMAEELA
SELNNRFFILARRFWPGPLTVIVPAAAKIPLKVTGNTGRLALRHARSPVADKLIALLNQPLISTSANISGHPTCHSGIDV
FGMMDGRVDLVLDGGTCVGEGSTTVDITEPYWRMIKEGAISEKEIAECLKPA
>Mature_211_residues
ATDLVEINTEDPQPEALERAAAAVRRGKVVAIPTDALYTLVADPYNLRAVTGVFQAKGREPHRALPILIRDSMMAEELAS
ELNNRFFILARRFWPGPLTVIVPAAAKIPLKVTGNTGRLALRHARSPVADKLIALLNQPLISTSANISGHPTCHSGIDVF
GMMDGRVDLVLDGGTCVGEGSTTVDITEPYWRMIKEGAISEKEIAECLKPA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=148, Percent_Identity=32.4324324324324, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI87081864, Length=201, Percent_Identity=23.8805970149254, Blast_Score=65, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17537239, Length=207, Percent_Identity=32.3671497584541, Blast_Score=83, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI193205175, Length=124, Percent_Identity=35.4838709677419, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=215, Percent_Identity=27.4418604651163, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 22906; Mature: 22775

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATDLVEINTEDPQPEALERAAAAVRRGKVVAIPTDALYTLVADPYNLRAVTGVFQAKGR
CCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEECCHHEEEECCCCCCHHHHHHHHHHCCC
EPHRALPILIRDSMMAEELASELNNRFFILARRFWPGPLTVIVPAAAKIPLKVTGNTGRL
CCCCCCCEEEHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEEECCCCCEEEEECCCCCE
ALRHARSPVADKLIALLNQPLISTSANISGHPTCHSGIDVFGMMDGRVDLVLDGGTCVGE
EEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEECCEEECC
GSTTVDITEPYWRMIKEGAISEKEIAECLKPA
CCCEEEECHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
ATDLVEINTEDPQPEALERAAAAVRRGKVVAIPTDALYTLVADPYNLRAVTGVFQAKGR
CCCEEEECCCCCCHHHHHHHHHHHHCCCEEEECCHHEEEECCCCCCHHHHHHHHHHCCC
EPHRALPILIRDSMMAEELASELNNRFFILARRFWPGPLTVIVPAAAKIPLKVTGNTGRL
CCCCCCCEEEHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEEECCCCCEEEEECCCCCE
ALRHARSPVADKLIALLNQPLISTSANISGHPTCHSGIDVFGMMDGRVDLVLDGGTCVGE
EEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEECCEEECC
GSTTVDITEPYWRMIKEGAISEKEIAECLKPA
CCCEEEECHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]