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The map label for this gene is pheA [H]

Identifier: 116626096

GI number: 116626096

Start: 8870233

End: 8871087

Strand: Direct

Name: pheA [H]

Synonym: Acid_7054

Alternate gene names: 116626096

Gene position: 8870233-8871087 (Clockwise)

Preceding gene: 116626095

Following gene: 116626097

Centisome position: 89.01

GC content: 54.5

Gene sequence:

>855_bases
GTGAGGCGCCGTACCGAAGTCATCGCGTTCCAGGGCGAGCGCGGCGCCTTCAGCGAGGAGGCAACGCGCAAGCTCTGCGG
CGCGGATATCGAAGTTCTTCCCTGTGTGCGTTTTGAGGATCTTTTCCGAGGCCTGAAAGAGGGGCGGGCGACCGGCGCCA
TCGTCCCGATCGAGAACACCCTGGCGGGCAGTGTCCACGAAAATTATGACCACCTGGTAAATTTCGAACTTCCGATTGTT
GCCGAGACTAATGTACGGATCGTGCACAATTTAATCGCGTTAAAAGGAGTGAAATTCTCGCAAATCAAACGGGTCTATTC
TCATCCAGTAGCATTAAATCAATGCCTGGATTTCTTTGCGAAGAATCCCGGAGTAGAGAGGACTCCTTTCTACGACACCG
CCGGAAGCGTAAAAATGATTCAAGAAGAAGGGCTTACGGACGCGGCTGGAATTGCGAGCGCCGTCGCAGCCGAAATTTAT
GACGCCCATATCCTTCGGCGATCCATTGAAAGCGACCGGCAGAATTTCACTCGATTTTTTCTTTTAAGAACTCCTGAGTA
TGCGCGCCGTAACCCGGTTCAGGTTCCGCAGGGCACGCAGTGGAAAACGTCGCTGGTTTTCAGCACTCGAAATATCCCAG
GAGCGCTGTTCCGGGCGCTCAGCGCGTTCGCACTGCGCGACCTCAACCTGATGAAGATCGAATCGAGACCGCTTCGGGGA
AAACCCTGGGAATATCTGTTCTACCTTGATTTTCTCGGCCGGTTCGATTCGCCGGTCGCGCAGAATGCCCTCAATCACCT
GCGCGAAACTGCGGACTTCCTCCGGATCCTGGGTTGTTATCCCAAGGGTGCCTAG

Upstream 100 bases:

>100_bases
CGCAAACCGTAATGGATATCGTGGACCACAGCGTAGACCGCGTCCTGGACCTGATGGGAATCGCCGATTCCGAGGTTCGC
CGCTGGGATGGGGTGAGCCG

Downstream 100 bases:

>100_bases
AGCGAACAACGCTAACGAATCGCACACTGTGCGGCCCACCTGCCCGTTACACTGAAGTTAGCGCCATGCCCGAAGAACAC
GAAGCTTCCGCCAGTGAAAA

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MRRRTEVIAFQGERGAFSEEATRKLCGADIEVLPCVRFEDLFRGLKEGRATGAIVPIENTLAGSVHENYDHLVNFELPIV
AETNVRIVHNLIALKGVKFSQIKRVYSHPVALNQCLDFFAKNPGVERTPFYDTAGSVKMIQEEGLTDAAGIASAVAAEIY
DAHILRRSIESDRQNFTRFFLLRTPEYARRNPVQVPQGTQWKTSLVFSTRNIPGALFRALSAFALRDLNLMKIESRPLRG
KPWEYLFYLDFLGRFDSPVAQNALNHLRETADFLRILGCYPKGA

Sequences:

>Translated_284_residues
MRRRTEVIAFQGERGAFSEEATRKLCGADIEVLPCVRFEDLFRGLKEGRATGAIVPIENTLAGSVHENYDHLVNFELPIV
AETNVRIVHNLIALKGVKFSQIKRVYSHPVALNQCLDFFAKNPGVERTPFYDTAGSVKMIQEEGLTDAAGIASAVAAEIY
DAHILRRSIESDRQNFTRFFLLRTPEYARRNPVQVPQGTQWKTSLVFSTRNIPGALFRALSAFALRDLNLMKIESRPLRG
KPWEYLFYLDFLGRFDSPVAQNALNHLRETADFLRILGCYPKGA
>Mature_284_residues
MRRRTEVIAFQGERGAFSEEATRKLCGADIEVLPCVRFEDLFRGLKEGRATGAIVPIENTLAGSVHENYDHLVNFELPIV
AETNVRIVHNLIALKGVKFSQIKRVYSHPVALNQCLDFFAKNPGVERTPFYDTAGSVKMIQEEGLTDAAGIASAVAAEIY
DAHILRRSIESDRQNFTRFFLLRTPEYARRNPVQVPQGTQWKTSLVFSTRNIPGALFRALSAFALRDLNLMKIESRPLRG
KPWEYLFYLDFLGRFDSPVAQNALNHLRETADFLRILGCYPKGA

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=277, Percent_Identity=33.5740072202166, Blast_Score=165, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6324013, Length=304, Percent_Identity=26.6447368421053, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 32092; Mature: 32092

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRTEVIAFQGERGAFSEEATRKLCGADIEVLPCVRFEDLFRGLKEGRATGAIVPIENT
CCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCEEEECCHH
LAGSVHENYDHLVNFELPIVAETNVRIVHNLIALKGVKFSQIKRVYSHPVALNQCLDFFA
HCCCHHHCHHHEEECCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHH
KNPGVERTPFYDTAGSVKMIQEEGLTDAAGIASAVAAEIYDAHILRRSIESDRQNFTRFF
CCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
LLRTPEYARRNPVQVPQGTQWKTSLVFSTRNIPGALFRALSAFALRDLNLMKIESRPLRG
EEECCHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCC
KPWEYLFYLDFLGRFDSPVAQNALNHLRETADFLRILGCYPKGA
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRRRTEVIAFQGERGAFSEEATRKLCGADIEVLPCVRFEDLFRGLKEGRATGAIVPIENT
CCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCEEEECCHH
LAGSVHENYDHLVNFELPIVAETNVRIVHNLIALKGVKFSQIKRVYSHPVALNQCLDFFA
HCCCHHHCHHHEEECCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHH
KNPGVERTPFYDTAGSVKMIQEEGLTDAAGIASAVAAEIYDAHILRRSIESDRQNFTRFF
CCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
LLRTPEYARRNPVQVPQGTQWKTSLVFSTRNIPGALFRALSAFALRDLNLMKIESRPLRG
EEECCHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCC
KPWEYLFYLDFLGRFDSPVAQNALNHLRETADFLRILGCYPKGA
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]