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The map label for this gene is rbsK [H]

Identifier: 116626027

GI number: 116626027

Start: 8773491

End: 8774435

Strand: Direct

Name: rbsK [H]

Synonym: Acid_6985

Alternate gene names: 116626027

Gene position: 8773491-8774435 (Clockwise)

Preceding gene: 116626019

Following gene: 116626029

Centisome position: 88.04

GC content: 67.62

Gene sequence:

>945_bases
ATGAGACGACAGCCGCGGATTGTGGTGATCGGCAGCGCAAACATCGACCTGGTCACTTACACCGACCAGTTCCCGCGTCC
CGGAGAAACCATATTCGGCCGCGAATTCAGCCTCGGCTTCGGCGGCAAAGGCGCCAACCAGGCCGTCGCGGCCCGACTCT
GCGGCGCCGAGGTGGCGATGGTGGCTCGCGTCGGCGACGATCTCTTCGGCCCCGCCAACATCCAGAACTTCACCTCGCGC
GGCATCGACGTCCGCCACGTCATGACCACCGCCGGCGTCTCCAGCGGCGTCGCGCCCATCTTCGTCGAAAGCTCCGGCCA
GAACCGCATCTGGGTCGTCAAAGGCGCCAACGACCGGCTCCTCCCCGCCGACGTCGCCGCCGCTTCAGACGTCCTCGCCG
GCGCCGACTTCCTGGTCATGCAGCTCGAAATCCCCACCGAGACCGTCTACTACGCTCTCCGCTTCGCCCGCGAGCGCGGC
ATCCGCACCATCCTGAATCCCGCCCCCGGCCAGGCGCTCGACCTCGCCCAAATCGCCTCCGCCGATTACGTCATTCCCAA
CGAGACCGAAGCCGAAGCTCTCGCCGGCACCCCCGTGCATGCCCTCGAAGACGCGCAGCGCTGTGCCCAGAAGCTGCTCG
ATGGTGGATTGCGCCGCGTGATCGTGACCCTCGGCGCCAACGGCGCGCTGCTCGCCACCCACGATGGCATGCACCACGTC
GCGCCCTTCCCTGTCCAGCCCATCGATACCACCGGCGCCGGCGACGCCTTCATCGGCAGCTTCGCCTGCTTCTGCGCCGA
GGGCTTCGACGAACTCGCCGCCATCGCCCGCGCCAATCTTTACGCGGCCCTCTCCACCCTCGGCCCCGGCACCCAAAAAT
CCTTCGTCTCCCGCGAACGCTTCAACACCGAGTGGGCCGCCCGCTCAGTCTCCGTAACTCCCTGA

Upstream 100 bases:

>100_bases
GCCGCCGCACCTCTACCGCGAAAAACTCAGGATAACGTTTGCACGAACGCCAAGTCAAATACGCCGCCCCCGACTACAAT
GAGATTTCTATGAGACGCCT

Downstream 100 bases:

>100_bases
CTCCGCCGGACACTCCACTTCCGCCATCCCCGGCATCGGCGCCGCCTCGCCCACCGCTTCCCAATTGCGCCGGTCGATCA
TCGTCGCCGGCTCATAGCTC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MRRQPRIVVIGSANIDLVTYTDQFPRPGETIFGREFSLGFGGKGANQAVAARLCGAEVAMVARVGDDLFGPANIQNFTSR
GIDVRHVMTTAGVSSGVAPIFVESSGQNRIWVVKGANDRLLPADVAAASDVLAGADFLVMQLEIPTETVYYALRFARERG
IRTILNPAPGQALDLAQIASADYVIPNETEAEALAGTPVHALEDAQRCAQKLLDGGLRRVIVTLGANGALLATHDGMHHV
APFPVQPIDTTGAGDAFIGSFACFCAEGFDELAAIARANLYAALSTLGPGTQKSFVSRERFNTEWAARSVSVTP

Sequences:

>Translated_314_residues
MRRQPRIVVIGSANIDLVTYTDQFPRPGETIFGREFSLGFGGKGANQAVAARLCGAEVAMVARVGDDLFGPANIQNFTSR
GIDVRHVMTTAGVSSGVAPIFVESSGQNRIWVVKGANDRLLPADVAAASDVLAGADFLVMQLEIPTETVYYALRFARERG
IRTILNPAPGQALDLAQIASADYVIPNETEAEALAGTPVHALEDAQRCAQKLLDGGLRRVIVTLGANGALLATHDGMHHV
APFPVQPIDTTGAGDAFIGSFACFCAEGFDELAAIARANLYAALSTLGPGTQKSFVSRERFNTEWAARSVSVTP
>Mature_314_residues
MRRQPRIVVIGSANIDLVTYTDQFPRPGETIFGREFSLGFGGKGANQAVAARLCGAEVAMVARVGDDLFGPANIQNFTSR
GIDVRHVMTTAGVSSGVAPIFVESSGQNRIWVVKGANDRLLPADVAAASDVLAGADFLVMQLEIPTETVYYALRFARERG
IRTILNPAPGQALDLAQIASADYVIPNETEAEALAGTPVHALEDAQRCAQKLLDGGLRRVIVTLGANGALLATHDGMHHV
APFPVQPIDTTGAGDAFIGSFACFCAEGFDELAAIARANLYAALSTLGPGTQKSFVSRERFNTEWAARSVSVTP

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=291, Percent_Identity=41.5807560137457, Blast_Score=191, Evalue=8e-49,
Organism=Escherichia coli, GI1790193, Length=267, Percent_Identity=41.9475655430712, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI87082343, Length=293, Percent_Identity=29.0102389078498, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788491, Length=276, Percent_Identity=23.9130434782609, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788017, Length=176, Percent_Identity=30.6818181818182, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=303, Percent_Identity=40.9240924092409, Blast_Score=209, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6319884, Length=324, Percent_Identity=29.9382716049383, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI20128807, Length=306, Percent_Identity=41.1764705882353, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24583886, Length=325, Percent_Identity=31.6923076923077, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33213; Mature: 33213

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRQPRIVVIGSANIDLVTYTDQFPRPGETIFGREFSLGFGGKGANQAVAARLCGAEVAM
CCCCCCEEEEECCCEEEEEECCCCCCCCCEECCCEEECCCCCCCCCHHHHHHHHHHHHHH
VARVGDDLFGPANIQNFTSRGIDVRHVMTTAGVSSGVAPIFVESSGQNRIWVVKGANDRL
HHHHCCCCCCCCCCHHHHHCCCEEEHHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCC
LPADVAAASDVLAGADFLVMQLEIPTETVYYALRFARERGIRTILNPAPGQALDLAQIAS
CCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHCC
ADYVIPNETEAEALAGTPVHALEDAQRCAQKLLDGGLRRVIVTLGANGALLATHDGMHHV
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCCCC
APFPVQPIDTTGAGDAFIGSFACFCAEGFDELAAIARANLYAALSTLGPGTQKSFVSRER
CCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FNTEWAARSVSVTP
CCHHHHHCEEECCC
>Mature Secondary Structure
MRRQPRIVVIGSANIDLVTYTDQFPRPGETIFGREFSLGFGGKGANQAVAARLCGAEVAM
CCCCCCEEEEECCCEEEEEECCCCCCCCCEECCCEEECCCCCCCCCHHHHHHHHHHHHHH
VARVGDDLFGPANIQNFTSRGIDVRHVMTTAGVSSGVAPIFVESSGQNRIWVVKGANDRL
HHHHCCCCCCCCCCHHHHHCCCEEEHHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCC
LPADVAAASDVLAGADFLVMQLEIPTETVYYALRFARERGIRTILNPAPGQALDLAQIAS
CCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHCC
ADYVIPNETEAEALAGTPVHALEDAQRCAQKLLDGGLRRVIVTLGANGALLATHDGMHHV
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCCCC
APFPVQPIDTTGAGDAFIGSFACFCAEGFDELAAIARANLYAALSTLGPGTQKSFVSRER
CCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FNTEWAARSVSVTP
CCHHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]