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The map label for this gene is ctaD [H]

Identifier: 116625950

GI number: 116625950

Start: 8678226

End: 8680121

Strand: Reverse

Name: ctaD [H]

Synonym: Acid_6908

Alternate gene names: 116625950

Gene position: 8680121-8678226 (Counterclockwise)

Preceding gene: 116625951

Following gene: 116625949

Centisome position: 87.1

GC content: 56.96

Gene sequence:

>1896_bases
ATGATACCGGCGGCCACAGAGCAGCACGCGTATGCGAATCTCGACATCCTGCGTCGAACGTGGAGCTCCAAACCCGGTCT
ATTAGGCTGGCTGTCGGAGACCAACCATAAGGAGATCGGCCGCCGGTATATCCTGACCGCGTTCGTGTTCCTTTTGATGG
GCGGTGTCGAAGCCCTACTGATGAGGCTGCAACTCGCGAAACCGGAGAACACGTTCCTATCGGCCGGACGATACAACCAG
ATCTTCACGCTCCACGGCACAACGATGATGTTTCTTTTTGCGGTGCCGGTGATGGAGGGCATGGGAGTTTATCTCGTCCC
GCTGATGATCGGAACGCGGAACGTGGCTTTTCCACGGCTCAATGCTTTCGGTTACTGGATGTATCTTGCAGGTGGACTTT
TGCTATACGGCAGTGTTCTCTTCAACATGATTCCAGATGCCGGGTGGTTTGCGTATCCTCCGCTTTCCGGGCCACAGTTC
TCGCCCGGGAAAGGGGTTGATGTCTGGGCGCAGATGATCACGTTTACCGAAATCTCGGCGCTATGCGTCGCAGTGGAACT
TATCGTGACCATTCTCAAAATGCGCGCCCCGGGAATGTCGTTGAATCGCATGCCCATGTATTGCTGGTCCATGCTCGTTC
AATCTTTCATGATCATTTTCGCGATGCCGGCCGTGATGCTCGCAAGCACGGTATTTCTGTTGAACGATCGAACTCTAGGC
ACGCATTTCGTCAATCCGGCGGAGGGCGGCGATCCGCTCCTCTACCAGCATGTGTTCTGGTTCTTCGGGCACCCGGAAGT
CTACATCATCTTCTTGCCCGCGCTCGGCATGATTTCCTCCATTTTGGAAACCCATACCCGCCGTCACATTTTCGGGTATC
CGGCGCTCGTGCTGTCGCTGGTCGGAAACGGCTTCATCGCGTTCGGCCTCTGGGTTCACCACATGTTCGCGACGGGTTTG
CCGCAAATCGGCGAAGCCTACTTCACCGCCGCCAGTATGATGATTGCCATCACCAGCGGAGTTCAAATTTTCTGTTGGCT
TGCGACTCTTTGGAGCGGAAGGCTGCGTTTGACCGCGGCCGTCCACTTCGTCTTAGGATTTATTTTCATCTTCGTGATGG
GTGGCATGACGGGTGTGATGCTAGCCTCGATTCCACTGGATCTCCAGACACACGACACATTCTTCGTGGTTGCCCATTTC
CACTACGTGCTTATCGGCGGCGCCCTCTTCCCCCTCTTTGGCGGCTTTCACTACTGGTTCCCCAAGTTCACGGGACGCCT
GATCGACGAGACACTCGGCAAGCTCTCGTTCTGGATTCTCTTCGTCGGTTTCAATCTCACGTTTTTCCCGATGCACTGGC
TCGGTATCGTCGGCATGACACGGCGTGTTTACACCTATGTCCCCGGTCTCGGATGGGAGCAGGCCAATCTCACGGCAACC
ATCGGAGCCTTCGTAATCCTGTCGGGAGGCGTCACCTTCATCGCCAACGTCCTTCGCAGCCGGCGTTCGGGCAAGCGTGC
GGGAAGCGATCCGTGGGACGCGAGCACTTTGGAATGGGAGACGGAATCGCCTCCTCCGCCCTACAACTTCCCGAACTTGC
CCGTCGTCCCGAGCCGTACTCCACTCTGGACACCATCGGCCGAACGCGCTATTGTCACCGGTCTTCGCGAAAATCGCCGT
GAAATTCTCATCACCAGCGTTCTCGACGCCCAAGCGCACCATCGATCCGTGCAGCCGCGGAATTCCATATGGCCGCTGCT
TACGGCCTTCGGGTTTTCGATCGGCCTGGCGGGTTCGATTTTCGCTTTCTCCTGGTACTACGTGGCGTCGGTGCTCGGCA
TGATCGGGTTGATCGGATGGTTCTGGCCGGAGCGGCCGCTGGAGGTGAACCCATGA

Upstream 100 bases:

>100_bases
TCGCCGATCCGCAAAACATCAAACCCGGGACCCACATGGCCACAGTGCCGATTCGGCCAGCCGAGATGCAGCCCCTGATC
GACTATTTGGAGAGCCTGAA

Downstream 100 bases:

>100_bases
CCGAGCGGCGCACGCTGGATGTCTCGGGCCTGCCGCCTTACGAAGTCTCGAACCAGTCGCCGCTGTTCTGGGGCCAGGTA
TTGATGTGCGTGATCGAGGG

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Caa-3605 subunit 1; Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MIPAATEQHAYANLDILRRTWSSKPGLLGWLSETNHKEIGRRYILTAFVFLLMGGVEALLMRLQLAKPENTFLSAGRYNQ
IFTLHGTTMMFLFAVPVMEGMGVYLVPLMIGTRNVAFPRLNAFGYWMYLAGGLLLYGSVLFNMIPDAGWFAYPPLSGPQF
SPGKGVDVWAQMITFTEISALCVAVELIVTILKMRAPGMSLNRMPMYCWSMLVQSFMIIFAMPAVMLASTVFLLNDRTLG
THFVNPAEGGDPLLYQHVFWFFGHPEVYIIFLPALGMISSILETHTRRHIFGYPALVLSLVGNGFIAFGLWVHHMFATGL
PQIGEAYFTAASMMIAITSGVQIFCWLATLWSGRLRLTAAVHFVLGFIFIFVMGGMTGVMLASIPLDLQTHDTFFVVAHF
HYVLIGGALFPLFGGFHYWFPKFTGRLIDETLGKLSFWILFVGFNLTFFPMHWLGIVGMTRRVYTYVPGLGWEQANLTAT
IGAFVILSGGVTFIANVLRSRRSGKRAGSDPWDASTLEWETESPPPPYNFPNLPVVPSRTPLWTPSAERAIVTGLRENRR
EILITSVLDAQAHHRSVQPRNSIWPLLTAFGFSIGLAGSIFAFSWYYVASVLGMIGLIGWFWPERPLEVNP

Sequences:

>Translated_631_residues
MIPAATEQHAYANLDILRRTWSSKPGLLGWLSETNHKEIGRRYILTAFVFLLMGGVEALLMRLQLAKPENTFLSAGRYNQ
IFTLHGTTMMFLFAVPVMEGMGVYLVPLMIGTRNVAFPRLNAFGYWMYLAGGLLLYGSVLFNMIPDAGWFAYPPLSGPQF
SPGKGVDVWAQMITFTEISALCVAVELIVTILKMRAPGMSLNRMPMYCWSMLVQSFMIIFAMPAVMLASTVFLLNDRTLG
THFVNPAEGGDPLLYQHVFWFFGHPEVYIIFLPALGMISSILETHTRRHIFGYPALVLSLVGNGFIAFGLWVHHMFATGL
PQIGEAYFTAASMMIAITSGVQIFCWLATLWSGRLRLTAAVHFVLGFIFIFVMGGMTGVMLASIPLDLQTHDTFFVVAHF
HYVLIGGALFPLFGGFHYWFPKFTGRLIDETLGKLSFWILFVGFNLTFFPMHWLGIVGMTRRVYTYVPGLGWEQANLTAT
IGAFVILSGGVTFIANVLRSRRSGKRAGSDPWDASTLEWETESPPPPYNFPNLPVVPSRTPLWTPSAERAIVTGLRENRR
EILITSVLDAQAHHRSVQPRNSIWPLLTAFGFSIGLAGSIFAFSWYYVASVLGMIGLIGWFWPERPLEVNP
>Mature_631_residues
MIPAATEQHAYANLDILRRTWSSKPGLLGWLSETNHKEIGRRYILTAFVFLLMGGVEALLMRLQLAKPENTFLSAGRYNQ
IFTLHGTTMMFLFAVPVMEGMGVYLVPLMIGTRNVAFPRLNAFGYWMYLAGGLLLYGSVLFNMIPDAGWFAYPPLSGPQF
SPGKGVDVWAQMITFTEISALCVAVELIVTILKMRAPGMSLNRMPMYCWSMLVQSFMIIFAMPAVMLASTVFLLNDRTLG
THFVNPAEGGDPLLYQHVFWFFGHPEVYIIFLPALGMISSILETHTRRHIFGYPALVLSLVGNGFIAFGLWVHHMFATGL
PQIGEAYFTAASMMIAITSGVQIFCWLATLWSGRLRLTAAVHFVLGFIFIFVMGGMTGVMLASIPLDLQTHDTFFVVAHF
HYVLIGGALFPLFGGFHYWFPKFTGRLIDETLGKLSFWILFVGFNLTFFPMHWLGIVGMTRRVYTYVPGLGWEQANLTAT
IGAFVILSGGVTFIANVLRSRRSGKRAGSDPWDASTLEWETESPPPPYNFPNLPVVPSRTPLWTPSAERAIVTGLRENRR
EILITSVLDAQAHHRSVQPRNSIWPLLTAFGFSIGLAGSIFAFSWYYVASVLGMIGLIGWFWPERPLEVNP

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=503, Percent_Identity=41.7495029821074, Blast_Score=378, Evalue=1e-104,
Organism=Escherichia coli, GI1786634, Length=521, Percent_Identity=41.2667946257198, Blast_Score=389, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6226519, Length=535, Percent_Identity=38.3177570093458, Blast_Score=369, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6226524, Length=326, Percent_Identity=38.3435582822086, Blast_Score=234, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6226523, Length=245, Percent_Identity=36.734693877551, Blast_Score=150, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 70530; Mature: 70530

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPAATEQHAYANLDILRRTWSSKPGLLGWLSETNHKEIGRRYILTAFVFLLMGGVEALL
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MRLQLAKPENTFLSAGRYNQIFTLHGTTMMFLFAVPVMEGMGVYLVPLMIGTRNVAFPRL
HHHHHCCCCCHHCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCH
NAFGYWMYLAGGLLLYGSVLFNMIPDAGWFAYPPLSGPQFSPGKGVDVWAQMITFTEISA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LCVAVELIVTILKMRAPGMSLNRMPMYCWSMLVQSFMIIFAMPAVMLASTVFLLNDRTLG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
THFVNPAEGGDPLLYQHVFWFFGHPEVYIIFLPALGMISSILETHTRRHIFGYPALVLSL
CCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VGNGFIAFGLWVHHMFATGLPQIGEAYFTAASMMIAITSGVQIFCWLATLWSGRLRLTAA
HCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
VHFVLGFIFIFVMGGMTGVMLASIPLDLQTHDTFFVVAHFHYVLIGGALFPLFGGFHYWF
HHHHHHHHHHHHHHCHHHHHHHHCCCCEECCCCEEHHHHHHHHHHHHHHHHHHCCHHHHH
PKFTGRLIDETLGKLSFWILFVGFNLTFFPMHWLGIVGMTRRVYTYVPGLGWEQANLTAT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
IGAFVILSGGVTFIANVLRSRRSGKRAGSDPWDASTLEWETESPPPPYNFPNLPVVPSRT
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
PLWTPSAERAIVTGLRENRREILITSVLDAQAHHRSVQPRNSIWPLLTAFGFSIGLAGSI
CCCCCCCCHHHHHHHHHCCHHEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCHHHH
FAFSWYYVASVLGMIGLIGWFWPERPLEVNP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIPAATEQHAYANLDILRRTWSSKPGLLGWLSETNHKEIGRRYILTAFVFLLMGGVEALL
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MRLQLAKPENTFLSAGRYNQIFTLHGTTMMFLFAVPVMEGMGVYLVPLMIGTRNVAFPRL
HHHHHCCCCCHHCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCH
NAFGYWMYLAGGLLLYGSVLFNMIPDAGWFAYPPLSGPQFSPGKGVDVWAQMITFTEISA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LCVAVELIVTILKMRAPGMSLNRMPMYCWSMLVQSFMIIFAMPAVMLASTVFLLNDRTLG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
THFVNPAEGGDPLLYQHVFWFFGHPEVYIIFLPALGMISSILETHTRRHIFGYPALVLSL
CCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VGNGFIAFGLWVHHMFATGLPQIGEAYFTAASMMIAITSGVQIFCWLATLWSGRLRLTAA
HCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
VHFVLGFIFIFVMGGMTGVMLASIPLDLQTHDTFFVVAHFHYVLIGGALFPLFGGFHYWF
HHHHHHHHHHHHHHCHHHHHHHHCCCCEECCCCEEHHHHHHHHHHHHHHHHHHCCHHHHH
PKFTGRLIDETLGKLSFWILFVGFNLTFFPMHWLGIVGMTRRVYTYVPGLGWEQANLTAT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
IGAFVILSGGVTFIANVLRSRRSGKRAGSDPWDASTLEWETESPPPPYNFPNLPVVPSRT
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
PLWTPSAERAIVTGLRENRREILITSVLDAQAHHRSVQPRNSIWPLLTAFGFSIGLAGSI
CCCCCCCCHHHHHHHHHCCHHEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCHHHH
FAFSWYYVASVLGMIGLIGWFWPERPLEVNP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377 [H]