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The map label for this gene is dsbD [H]

Identifier: 116625806

GI number: 116625806

Start: 8467487

End: 8469745

Strand: Reverse

Name: dsbD [H]

Synonym: Acid_6757

Alternate gene names: 116625806

Gene position: 8469745-8467487 (Counterclockwise)

Preceding gene: 116625807

Following gene: 116625803

Centisome position: 84.99

GC content: 63.17

Gene sequence:

>2259_bases
ATGAAGTCGGCGATCTTGGGGCTCTTCCTGGCAGCCTCCGCTCTCTACTCGCAAGACCAACACGTAACTTGGAAAGTCAC
CGTGGAACCCCCGTCCGCGGGCCCCGGCAGCACCGTGCTGCTCCGCATGGCCGGACACATCGAGGAAGGCTGGCACCTCT
ACTCGATGTCCACCCCCGCCGCCATCCCTACCAAAATCCAGCTCGCCCCCAGCCCCGCCGTGGAGAGCTTTCGCGCCCTG
CAGCCGGAGCCCAAACGCGCCTTTGACGCCAACTTCAATTCCGACACCGAAACCTACGAAGGCGAAGTCGCCTTCCTCCT
GGAAGTCCATTTGAAGAAGGACGCCCCGGCCGGCCCAGCCGAGCTTGCCCTCTCCGCTCGCTACCAGACCTGCAATCCCA
AGATGTGCGTTCCCTCCAAGTGGAGCGGCTCCGCCACCATCGCTATCGATCCCGCCGCTCCGGCCTCGACCGCAACCATC
CCCGCCGGATACTCCGAACCCAAGCCCCACACCGCGAATCCAGCGACGTCCACCAGCGCCGCCGCACCCCCCGAAGGCCT
CGCCGCCTTCCTGGCCGTCGCCTTCGGCTTCGGCCTCGCTTCCATCTTTACCCCCTGCGTCTTCCCCATGATCCCGATCA
CGATGTCCTACTTCGTCAACCGCCAGTCCGGCGGCCGCCGCGAAAGCATCGTGCAGGCCCTTGTCTTCTGCCTCGGCATC
GTAGTCCTTTTCTCTGGGCTCGGCCTCGCCACCACCGCCATCCTCGGCCCCTTCGGCATCGTCACGCTCGGCTCCAACCC
GTGGGTCAACGGCTTCATTTCCGCGCTCTTCATTGCCTTCGGACTCAGCCTGCTCGGCGCCTTCGAAATCACCATCCCAT
CGTCGATCCTCACTCCCCTCAACAAATCGGCCGACAAGGGCGGCTTCCTCGGCAGCCTGCTGATGGGCCTCACCTTCTCC
CTCGCCAGCTTCGCCTGTGTCGGACCGTTCGTCGGCACCCTGCTCGCCGCCTCCGTTTCCGGCGGCAAGACGCGCCCCCT
GATCGGCATGGTGACCTTCGCCACCGGGCTTGCTCTCCCGTTCTTCCTTCTCGCCGTCTTCCCCGGCTATCTCAAACGCA
TGCCGCGCTCCGGCGGCTGGATGGCCCGCGTGAAAGTCGTGATGGGCTTCATCATCCTCGCCTTCAGCCTCAAATACCTC
AGCAGCCTCGACCAGGTCCTCCAGTGGGGCATCCTTACCCGCGAGCGCTTCCTTGCCGCCTGGGTGGTTCTCTTCGCCAT
GGCCGGCCTCTACCTGCTCGGCTTCCTCCGCATGGAGGGCATCAAGCCCGATGAGCCTGTCGGACTCGGACGCCTGCTCC
CCGGCGCCGCGTTCCTGATCTTTGCGATCAGCCTGCTTCCCGGCATGTTCGGCGGCAAACTCGGCGATCTCGATGCCTAT
GTCCCGCTCGCCTCCAGCCAGTCCGCCGGCATCGGTGGGGGGGCCGGCGAATCGTCGCTCGTGTGGATGAAGAACCAGTA
CCGCGAAGCCCTCGACCGCGCCCGCAAGGAGGGTAAGCTCGTCCTCGTCAACTTCACCGGCTACGCCTGCACCAACTGCC
ATTGGATGAAGGCCAACATGTTCACCCGCCCCGAAATCGCGGCCGCCATGAAGAACTTCGTCCTGGTGGAACTCTATACC
GATGGCACCGACGCCGAATCCGAAGCCCACCAGAAGCTTCAGCTCTCCAAATTCAACACCGTCGCGATCCCCTTCTACGC
CATCATCGACCCCGATGAGAAAGTGGTCGCCACCTTCCCCGGCCTGACCAAAGATTCCGCCGAGTACCTCGCCTTTCTGC
AGAAGACCCCCGCGCCCTTAAACGTAAACGCGAGTGCCTTCCCGCAGTTTTCAAAACTGGACGGCGCCCCCGCCGACACC
GCCGGCCTTTCCGGCAAAGTCGTGGTAGTGAATTTCTGGGCCACCTGGTGTGTCCCCTGCATTCAGGAAATCCCCGGCTT
CAACAAACTCCACAAAGACGGCGTCTCCGTAGTCGGCATTGCGATGGATGAAGAAGGCGCCGCCCGCGTCGAACCCTTCC
TTAAAAAACACCCGATGGATTACCCCGTGGGTATAGGCAGCGAGGCGCTCAATGAACAGTTCAACCTCGACCAGCTCCCC
GTCACCCTCGTCTTCGATCGTGCCGGTAAACAAATCAAACGTTTCGAAGGCTTCACCCCGGACGCCGAAATCCTCGCCGC
CGTCAAACAAGCCCTGTAA

Upstream 100 bases:

>100_bases
CAGATCGAAGAGGAACTCCTCCGTCTTGGAAAAGCCGGGGATTAACAGTTTTAGCGGAATAAAACCGGGGACCTCCCACA
TCTAATTCTTGGAGGCAAGC

Downstream 100 bases:

>100_bases
GCCCACCCGGCCCATCTTCTGCATTTGTCTGCCGCACTGTACTACATTTGCTCGCTGCCCGCAAAGATTGCAGGGCCTGC
CTTTGTGGGGCAGGCATTTT

Product: redoxin domain-containing protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 752; Mature: 752

Protein sequence:

>752_residues
MKSAILGLFLAASALYSQDQHVTWKVTVEPPSAGPGSTVLLRMAGHIEEGWHLYSMSTPAAIPTKIQLAPSPAVESFRAL
QPEPKRAFDANFNSDTETYEGEVAFLLEVHLKKDAPAGPAELALSARYQTCNPKMCVPSKWSGSATIAIDPAAPASTATI
PAGYSEPKPHTANPATSTSAAAPPEGLAAFLAVAFGFGLASIFTPCVFPMIPITMSYFVNRQSGGRRESIVQALVFCLGI
VVLFSGLGLATTAILGPFGIVTLGSNPWVNGFISALFIAFGLSLLGAFEITIPSSILTPLNKSADKGGFLGSLLMGLTFS
LASFACVGPFVGTLLAASVSGGKTRPLIGMVTFATGLALPFFLLAVFPGYLKRMPRSGGWMARVKVVMGFIILAFSLKYL
SSLDQVLQWGILTRERFLAAWVVLFAMAGLYLLGFLRMEGIKPDEPVGLGRLLPGAAFLIFAISLLPGMFGGKLGDLDAY
VPLASSQSAGIGGGAGESSLVWMKNQYREALDRARKEGKLVLVNFTGYACTNCHWMKANMFTRPEIAAAMKNFVLVELYT
DGTDAESEAHQKLQLSKFNTVAIPFYAIIDPDEKVVATFPGLTKDSAEYLAFLQKTPAPLNVNASAFPQFSKLDGAPADT
AGLSGKVVVVNFWATWCVPCIQEIPGFNKLHKDGVSVVGIAMDEEGAARVEPFLKKHPMDYPVGIGSEALNEQFNLDQLP
VTLVFDRAGKQIKRFEGFTPDAEILAAVKQAL

Sequences:

>Translated_752_residues
MKSAILGLFLAASALYSQDQHVTWKVTVEPPSAGPGSTVLLRMAGHIEEGWHLYSMSTPAAIPTKIQLAPSPAVESFRAL
QPEPKRAFDANFNSDTETYEGEVAFLLEVHLKKDAPAGPAELALSARYQTCNPKMCVPSKWSGSATIAIDPAAPASTATI
PAGYSEPKPHTANPATSTSAAAPPEGLAAFLAVAFGFGLASIFTPCVFPMIPITMSYFVNRQSGGRRESIVQALVFCLGI
VVLFSGLGLATTAILGPFGIVTLGSNPWVNGFISALFIAFGLSLLGAFEITIPSSILTPLNKSADKGGFLGSLLMGLTFS
LASFACVGPFVGTLLAASVSGGKTRPLIGMVTFATGLALPFFLLAVFPGYLKRMPRSGGWMARVKVVMGFIILAFSLKYL
SSLDQVLQWGILTRERFLAAWVVLFAMAGLYLLGFLRMEGIKPDEPVGLGRLLPGAAFLIFAISLLPGMFGGKLGDLDAY
VPLASSQSAGIGGGAGESSLVWMKNQYREALDRARKEGKLVLVNFTGYACTNCHWMKANMFTRPEIAAAMKNFVLVELYT
DGTDAESEAHQKLQLSKFNTVAIPFYAIIDPDEKVVATFPGLTKDSAEYLAFLQKTPAPLNVNASAFPQFSKLDGAPADT
AGLSGKVVVVNFWATWCVPCIQEIPGFNKLHKDGVSVVGIAMDEEGAARVEPFLKKHPMDYPVGIGSEALNEQFNLDQLP
VTLVFDRAGKQIKRFEGFTPDAEILAAVKQAL
>Mature_752_residues
MKSAILGLFLAASALYSQDQHVTWKVTVEPPSAGPGSTVLLRMAGHIEEGWHLYSMSTPAAIPTKIQLAPSPAVESFRAL
QPEPKRAFDANFNSDTETYEGEVAFLLEVHLKKDAPAGPAELALSARYQTCNPKMCVPSKWSGSATIAIDPAAPASTATI
PAGYSEPKPHTANPATSTSAAAPPEGLAAFLAVAFGFGLASIFTPCVFPMIPITMSYFVNRQSGGRRESIVQALVFCLGI
VVLFSGLGLATTAILGPFGIVTLGSNPWVNGFISALFIAFGLSLLGAFEITIPSSILTPLNKSADKGGFLGSLLMGLTFS
LASFACVGPFVGTLLAASVSGGKTRPLIGMVTFATGLALPFFLLAVFPGYLKRMPRSGGWMARVKVVMGFIILAFSLKYL
SSLDQVLQWGILTRERFLAAWVVLFAMAGLYLLGFLRMEGIKPDEPVGLGRLLPGAAFLIFAISLLPGMFGGKLGDLDAY
VPLASSQSAGIGGGAGESSLVWMKNQYREALDRARKEGKLVLVNFTGYACTNCHWMKANMFTRPEIAAAMKNFVLVELYT
DGTDAESEAHQKLQLSKFNTVAIPFYAIIDPDEKVVATFPGLTKDSAEYLAFLQKTPAPLNVNASAFPQFSKLDGAPADT
AGLSGKVVVVNFWATWCVPCIQEIPGFNKLHKDGVSVVGIAMDEEGAARVEPFLKKHPMDYPVGIGSEALNEQFNLDQLP
VTLVFDRAGKQIKRFEGFTPDAEILAAVKQAL

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=561, Percent_Identity=22.2816399286988, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 80153; Mature: 80153

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAILGLFLAASALYSQDQHVTWKVTVEPPSAGPGSTVLLRMAGHIEEGWHLYSMSTPA
CCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEECCCCC
AIPTKIQLAPSPAVESFRALQPEPKRAFDANFNSDTETYEGEVAFLLEVHLKKDAPAGPA
CCCEEEEECCCHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHH
ELALSARYQTCNPKMCVPSKWSGSATIAIDPAAPASTATIPAGYSEPKPHTANPATSTSA
HHHEEHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAPPEGLAAFLAVAFGFGLASIFTPCVFPMIPITMSYFVNRQSGGRRESIVQALVFCLGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VVLFSGLGLATTAILGPFGIVTLGSNPWVNGFISALFIAFGLSLLGAFEITIPSSILTPL
HHHHCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHC
NKSADKGGFLGSLLMGLTFSLASFACVGPFVGTLLAASVSGGKTRPLIGMVTFATGLALP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
FFLLAVFPGYLKRMPRSGGWMARVKVVMGFIILAFSLKYLSSLDQVLQWGILTRERFLAA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVVLFAMAGLYLLGFLRMEGIKPDEPVGLGRLLPGAAFLIFAISLLPGMFGGKLGDLDAY
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
VPLASSQSAGIGGGAGESSLVWMKNQYREALDRARKEGKLVLVNFTGYACTNCHWMKANM
EECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCEEEEEECCEEECCEEEEECCC
FTRPEIAAAMKNFVLVELYTDGTDAESEAHQKLQLSKFNTVAIPFYAIIDPDEKVVATFP
CCCHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEEECCCCCEEEECC
GLTKDSAEYLAFLQKTPAPLNVNASAFPQFSKLDGAPADTAGLSGKVVVVNFWATWCVPC
CCCCCHHHHHHHHHCCCCCCCCCHHCCCCHHHCCCCCCCCCCCCCCEEEEECHHHHHHHH
IQEIPGFNKLHKDGVSVVGIAMDEEGAARVEPFLKKHPMDYPVGIGSEALNEQFNLDQLP
HHHCCCCCHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCC
VTLVFDRAGKQIKRFEGFTPDAEILAAVKQAL
EEEEECCCCHHHHHHCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MKSAILGLFLAASALYSQDQHVTWKVTVEPPSAGPGSTVLLRMAGHIEEGWHLYSMSTPA
CCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEECCCCC
AIPTKIQLAPSPAVESFRALQPEPKRAFDANFNSDTETYEGEVAFLLEVHLKKDAPAGPA
CCCEEEEECCCHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHH
ELALSARYQTCNPKMCVPSKWSGSATIAIDPAAPASTATIPAGYSEPKPHTANPATSTSA
HHHEEHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAPPEGLAAFLAVAFGFGLASIFTPCVFPMIPITMSYFVNRQSGGRRESIVQALVFCLGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VVLFSGLGLATTAILGPFGIVTLGSNPWVNGFISALFIAFGLSLLGAFEITIPSSILTPL
HHHHCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHC
NKSADKGGFLGSLLMGLTFSLASFACVGPFVGTLLAASVSGGKTRPLIGMVTFATGLALP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
FFLLAVFPGYLKRMPRSGGWMARVKVVMGFIILAFSLKYLSSLDQVLQWGILTRERFLAA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVVLFAMAGLYLLGFLRMEGIKPDEPVGLGRLLPGAAFLIFAISLLPGMFGGKLGDLDAY
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
VPLASSQSAGIGGGAGESSLVWMKNQYREALDRARKEGKLVLVNFTGYACTNCHWMKANM
EECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCEEEEEECCEEECCEEEEECCC
FTRPEIAAAMKNFVLVELYTDGTDAESEAHQKLQLSKFNTVAIPFYAIIDPDEKVVATFP
CCCHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEEECCCCCEEEECC
GLTKDSAEYLAFLQKTPAPLNVNASAFPQFSKLDGAPADTAGLSGKVVVVNFWATWCVPC
CCCCCHHHHHHHHHCCCCCCCCCHHCCCCHHHCCCCCCCCCCCCCCEEEEECHHHHHHHH
IQEIPGFNKLHKDGVSVVGIAMDEEGAARVEPFLKKHPMDYPVGIGSEALNEQFNLDQLP
HHHCCCCCHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCC
VTLVFDRAGKQIKRFEGFTPDAEILAAVKQAL
EEEEECCCCHHHHHHCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA