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The map label for this gene is flp [H]

Identifier: 116625801

GI number: 116625801

Start: 8457530

End: 8459623

Strand: Reverse

Name: flp [H]

Synonym: Acid_6751

Alternate gene names: 116625801

Gene position: 8459623-8457530 (Counterclockwise)

Preceding gene: 116625803

Following gene: 116625800

Centisome position: 84.89

GC content: 61.65

Gene sequence:

>2094_bases
ATGTTTTCACGTGTAACATCATTCCGCTGCTGCCTCCTCATCGCCTCCATCTGGTGTGCCTTTACACAGGAACTAACGCC
GGACGACCTGCCGCCCGGGATGCAACTCGTCATTCGAGACCTTGATCGCATAGCCACCGAAGCCGCCAGGAATCCCACCG
ACATCGGCTATACATTGGGTGTGGTCAATCAGGACCGGTTGGCCTGGACCAAAAGCTATGGATATGCCGCCGCCACCCGG
CAGCAGCTCGCAACCGCGGACACCGTCTACGGTATTGGCTCTGCCGCATTCACTGCGATCATGCTCCTCCAGTTGACGCG
GGCCGGTACCGTCCATCTGTCCGATCCGGTGGAGCGATATCTCCCCGAAATGAAGTCCGTGCACAACCCATACCCCGGCG
CCGCGCCGGTCACTCTTCTGCAGTTGGCCATTCACACCTCCGGATTGGCCCTGGATAGCCGGGATGCCGCCACATACACA
AGCGGCTCAGCCGCGCAGTGGGAGAATACGCTGATTGCGGCCTTGCCTCACACCAGCTACGAATTTGAGCTCGGTACGCA
CGCCGCGTCTTCCAATATCGATGAGTCGATCCTCGCCCTCGCTCTCAGCCGGGCCGCGCACCAGCCCTACAGCGACTATC
TCAAGCACCGGATCCTGTTGCCAATGGGCATGACTCACACTGAGTTTTTAGTAAGTGGGGCAGAAACTTCAGGTCTGGGA
TTCAGGCCGGCAGTGTACACAACCATCGGGGACCTGGCGCGGTTTGCCTCCTTCATGATGCTCCACGGTCCCGAAGCCGT
CCTCCCCCGGCGCGATCTCGAGGCGAACTACCGGCGGCTTTGGGTCACCAACTCCATCGCCATCCCCAATCCCAACGAGG
GATATGGCATTGGCTTCCACGGCGAAACCTGGACCAGTAACCACTACTACTTTATTCCGCCAGTCGCATTCCCTGGTGCC
GCATACGAGGCCGCGCTTTGGTTTGAGCCGCGCCGCCATGCGGCCATGATCCTCCTGCACCACGGCAGCTCCGGCACTGC
GCTCGGCCAGATGATCCATTCGTATGTCTATACGCTCAATGCCCAGAAGAACGACGCCGGACGGCAGGAGCCGGTACGCC
CTTTTCCCTACACGGAAGAGGAGGTTTCCTTCGAAAACAAAGCCGCGGAGATCCGGCTGGCAGGCACACTCACCATTCCG
CAAGGTAAAGGACCGTTTCTCGCCGTGATCCTGATCCCGAAATCGGGGCCGCTGGATCGCGACGAGCGGCTGTTCAACCA
CCGTCCTTTCTTCATCCTCGCGGACTATCTGACGCGCGCCGGCATCGCCGTCTTACGCGCCGACGTCCGCGGCGTCGGAA
AATCCGGTGGGAAGTTCGGCCCCGCGCCCATGGACGATTCCGCCGCCGATGCCGAGGCAGCCCTGGCATACCTGAAGACG
CGGCCGGAGGTAAATCCCCGCGGCATCGGACTCCTCAGCCACGGCGAGGGCGGTCTTGCAGCCTCCATCGTGGCTGCGCG
AAACCGGGATGTGGCATTCCTGGCGATGCTGAGCGCGCCCGCGGTCCGCGCCGCTGAAAACTCAGTGGAGTCGAGCCGGT
TGAATGCCGTCGCCAACGGAGAACTCGATCGGAAGGCCGACGACCAGGCCGGGCAGTCGCGCAAGATCTTCTCCATAATC
CAGGAAGAGCGCGATCCCGCGTCTCTCGATCGCAAGCTGCGCGACGTTCTTGCGGGGAAACTCCCGGAGGCGCAACTTGC
CGGACAGATCAGGCAGTGGAGCTCGCCGGCATTCCGGCGCACGATCACCTACGATCCGGCGCCCGCATTGAGCAAGCTCG
CCTGCCCCGTGCTCGCCCTTTATGCGGAGAAGGACCTGTCCGTCCCGGCAAACTTGAACGTGCCGGCGATGCGAGCTGCC
CGGGAAGCCTCCGGGAATAAGAACTTCACCGTGGAGGAATTGCCCGATCTGAACCTGCTCTTTCAGACTGCCGACGTCGG
TATCGGAAGAGAGGCCAATTGGACCGAAGAAACGATCTCACCGGTCGTGCTCGGGAAGCTCGCAAACTGGCTTTCGCAAC
TACCCGTGCGATGA

Upstream 100 bases:

>100_bases
TTATGGAGCAGTTGCCAATTCACTGCCCTCCGACAAGTTACAACCGCTCGCACTAACCATTCACCTTGAATCTCGTCCCC
TGACTTACGGGTAACTGTAG

Downstream 100 bases:

>100_bases
TCTGGCGGCACAAGTGTGAAATTCAACTGGCCTCTTCGGAATCGCGAAAAGTGGATCTGGCGCCAATGCCAGCTCCCCGC
TACTTTACATGTTATGGAAG

Product: beta-lactamase

Products: NA

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MFSRVTSFRCCLLIASIWCAFTQELTPDDLPPGMQLVIRDLDRIATEAARNPTDIGYTLGVVNQDRLAWTKSYGYAAATR
QQLATADTVYGIGSAAFTAIMLLQLTRAGTVHLSDPVERYLPEMKSVHNPYPGAAPVTLLQLAIHTSGLALDSRDAATYT
SGSAAQWENTLIAALPHTSYEFELGTHAASSNIDESILALALSRAAHQPYSDYLKHRILLPMGMTHTEFLVSGAETSGLG
FRPAVYTTIGDLARFASFMMLHGPEAVLPRRDLEANYRRLWVTNSIAIPNPNEGYGIGFHGETWTSNHYYFIPPVAFPGA
AYEAALWFEPRRHAAMILLHHGSSGTALGQMIHSYVYTLNAQKNDAGRQEPVRPFPYTEEEVSFENKAAEIRLAGTLTIP
QGKGPFLAVILIPKSGPLDRDERLFNHRPFFILADYLTRAGIAVLRADVRGVGKSGGKFGPAPMDDSAADAEAALAYLKT
RPEVNPRGIGLLSHGEGGLAASIVAARNRDVAFLAMLSAPAVRAAENSVESSRLNAVANGELDRKADDQAGQSRKIFSII
QEERDPASLDRKLRDVLAGKLPEAQLAGQIRQWSSPAFRRTITYDPAPALSKLACPVLALYAEKDLSVPANLNVPAMRAA
REASGNKNFTVEELPDLNLLFQTADVGIGREANWTEETISPVVLGKLANWLSQLPVR

Sequences:

>Translated_697_residues
MFSRVTSFRCCLLIASIWCAFTQELTPDDLPPGMQLVIRDLDRIATEAARNPTDIGYTLGVVNQDRLAWTKSYGYAAATR
QQLATADTVYGIGSAAFTAIMLLQLTRAGTVHLSDPVERYLPEMKSVHNPYPGAAPVTLLQLAIHTSGLALDSRDAATYT
SGSAAQWENTLIAALPHTSYEFELGTHAASSNIDESILALALSRAAHQPYSDYLKHRILLPMGMTHTEFLVSGAETSGLG
FRPAVYTTIGDLARFASFMMLHGPEAVLPRRDLEANYRRLWVTNSIAIPNPNEGYGIGFHGETWTSNHYYFIPPVAFPGA
AYEAALWFEPRRHAAMILLHHGSSGTALGQMIHSYVYTLNAQKNDAGRQEPVRPFPYTEEEVSFENKAAEIRLAGTLTIP
QGKGPFLAVILIPKSGPLDRDERLFNHRPFFILADYLTRAGIAVLRADVRGVGKSGGKFGPAPMDDSAADAEAALAYLKT
RPEVNPRGIGLLSHGEGGLAASIVAARNRDVAFLAMLSAPAVRAAENSVESSRLNAVANGELDRKADDQAGQSRKIFSII
QEERDPASLDRKLRDVLAGKLPEAQLAGQIRQWSSPAFRRTITYDPAPALSKLACPVLALYAEKDLSVPANLNVPAMRAA
REASGNKNFTVEELPDLNLLFQTADVGIGREANWTEETISPVVLGKLANWLSQLPVR
>Mature_697_residues
MFSRVTSFRCCLLIASIWCAFTQELTPDDLPPGMQLVIRDLDRIATEAARNPTDIGYTLGVVNQDRLAWTKSYGYAAATR
QQLATADTVYGIGSAAFTAIMLLQLTRAGTVHLSDPVERYLPEMKSVHNPYPGAAPVTLLQLAIHTSGLALDSRDAATYT
SGSAAQWENTLIAALPHTSYEFELGTHAASSNIDESILALALSRAAHQPYSDYLKHRILLPMGMTHTEFLVSGAETSGLG
FRPAVYTTIGDLARFASFMMLHGPEAVLPRRDLEANYRRLWVTNSIAIPNPNEGYGIGFHGETWTSNHYYFIPPVAFPGA
AYEAALWFEPRRHAAMILLHHGSSGTALGQMIHSYVYTLNAQKNDAGRQEPVRPFPYTEEEVSFENKAAEIRLAGTLTIP
QGKGPFLAVILIPKSGPLDRDERLFNHRPFFILADYLTRAGIAVLRADVRGVGKSGGKFGPAPMDDSAADAEAALAYLKT
RPEVNPRGIGLLSHGEGGLAASIVAARNRDVAFLAMLSAPAVRAAENSVESSRLNAVANGELDRKADDQAGQSRKIFSII
QEERDPASLDRKLRDVLAGKLPEAQLAGQIRQWSSPAFRRTITYDPAPALSKLACPVLALYAEKDLSVPANLNVPAMRAA
REASGNKNFTVEELPDLNLLFQTADVGIGREANWTEETISPVVLGKLANWLSQLPVR

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786574, Length=233, Percent_Identity=27.8969957081545, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 75827; Mature: 75827

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSRVTSFRCCLLIASIWCAFTQELTPDDLPPGMQLVIRDLDRIATEAARNPTDIGYTLG
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VVNQDRLAWTKSYGYAAATRQQLATADTVYGIGSAAFTAIMLLQLTRAGTVHLSDPVERY
ECCCCHHEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCHHHHH
LPEMKSVHNPYPGAAPVTLLQLAIHTSGLALDSRDAATYTSGSAAQWENTLIAALPHTSY
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCEEEEEECCCCE
EFELGTHAASSNIDESILALALSRAAHQPYSDYLKHRILLPMGMTHTEFLVSGAETSGLG
EEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCHHHHHEECCCCCCCC
FRPAVYTTIGDLARFASFMMLHGPEAVLPRRDLEANYRRLWVTNSIAIPNPNEGYGIGFH
CCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCEEEEEECEEECCCCCCCCEECCC
GETWTSNHYYFIPPVAFPGAAYEAALWFEPRRHAAMILLHHGSSGTALGQMIHSYVYTLN
CCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHEEEC
AQKNDAGRQEPVRPFPYTEEEVSFENKAAEIRLAGTLTIPQGKGPFLAVILIPKSGPLDR
CCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEEEEEEEECCCCCCEEEEEEEECCCCCCH
DERLFNHRPFFILADYLTRAGIAVLRADVRGVGKSGGKFGPAPMDDSAADAEAALAYLKT
HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
RPEVNPRGIGLLSHGEGGLAASIVAARNRDVAFLAMLSAPAVRAAENSVESSRLNAVANG
CCCCCCCCEEEEECCCCCCEEEEEHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEECC
ELDRKADDQAGQSRKIFSIIQEERDPASLDRKLRDVLAGKLPEAQLAGQIRQWSSPAFRR
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHEE
TITYDPAPALSKLACPVLALYAEKDLSVPANLNVPAMRAAREASGNKNFTVEELPDLNLL
EEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEHHHCCCCEEE
FQTADVGIGREANWTEETISPVVLGKLANWLSQLPVR
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFSRVTSFRCCLLIASIWCAFTQELTPDDLPPGMQLVIRDLDRIATEAARNPTDIGYTLG
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VVNQDRLAWTKSYGYAAATRQQLATADTVYGIGSAAFTAIMLLQLTRAGTVHLSDPVERY
ECCCCHHEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCHHHHH
LPEMKSVHNPYPGAAPVTLLQLAIHTSGLALDSRDAATYTSGSAAQWENTLIAALPHTSY
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCEEEEEECCCCE
EFELGTHAASSNIDESILALALSRAAHQPYSDYLKHRILLPMGMTHTEFLVSGAETSGLG
EEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCHHHHHEECCCCCCCC
FRPAVYTTIGDLARFASFMMLHGPEAVLPRRDLEANYRRLWVTNSIAIPNPNEGYGIGFH
CCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCEEEEEECEEECCCCCCCCEECCC
GETWTSNHYYFIPPVAFPGAAYEAALWFEPRRHAAMILLHHGSSGTALGQMIHSYVYTLN
CCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHEEEC
AQKNDAGRQEPVRPFPYTEEEVSFENKAAEIRLAGTLTIPQGKGPFLAVILIPKSGPLDR
CCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEEEEEEEECCCCCCEEEEEEEECCCCCCH
DERLFNHRPFFILADYLTRAGIAVLRADVRGVGKSGGKFGPAPMDDSAADAEAALAYLKT
HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
RPEVNPRGIGLLSHGEGGLAASIVAARNRDVAFLAMLSAPAVRAAENSVESSRLNAVANG
CCCCCCCCEEEEECCCCCCEEEEEHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEECC
ELDRKADDQAGQSRKIFSIIQEERDPASLDRKLRDVLAGKLPEAQLAGQIRQWSSPAFRR
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHEE
TITYDPAPALSKLACPVLALYAEKDLSVPANLNVPAMRAAREASGNKNFTVEELPDLNLL
EEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEHHHCCCCEEE
FQTADVGIGREANWTEETISPVVLGKLANWLSQLPVR
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA