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The map label for this gene is dtd

Identifier: 116625767

GI number: 116625767

Start: 8417845

End: 8418300

Strand: Direct

Name: dtd

Synonym: Acid_6717

Alternate gene names: 116625767

Gene position: 8417845-8418300 (Clockwise)

Preceding gene: 116625766

Following gene: 116625768

Centisome position: 84.47

GC content: 53.73

Gene sequence:

>456_bases
ATGAAACTCGTAATCCAGCGAGTAAGCCAAGCCCATGTAAACGTGGAGGGTACCACGGTCGGGGCTATACGTACCGGCTT
AGTCGTGCTTGTCGGTATCTCAAAATCCGACACAATCAAGGACGCGGATTATCTTGCCGATAAGGTGCTCGGTCTCCGCA
TTTTTCCAGACAATGAGGGCAAAATGAACCGAAATGTGGCGGAGGCGCACGGCGCGATTTTAATTATTTCGCAATTTACG
CTGTACGGCGACTGCCGGCGCGGACGCCGCCCGAGCTTCGATGCCGCCGCCGCGCCCGGCGAGGCTTTGACTCTTTATAA
TTACTTCGTAGACACGGTCCGAAAGAGCCCGGTACCAGTGGAAACAGGCACCTTCCAGGCGACCATGGAGGTTTCCCTGG
TAAACCAAGGTCCTGTAACTATAGTGATCGAATCGGAGGAGCGAAACAGAAAATGA

Upstream 100 bases:

>100_bases
CTCTTGCCATTGCTTCACCCAGGAACAATATATCATAGGGTTTTACCGTGTATACACAAAAGTGCAGGCTACTTAAGTTC
CATTCTGACTAGGACTATAC

Downstream 100 bases:

>100_bases
TCGAGACATACGGCTACGCACGCGCCGGGTTTTTGGGCAACCCCAGCGACGGATATTTCGGAAAAACGTTATCTTTCGCT
ATGTCGAACTTTCGCGCGCG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKLVIQRVSQAHVNVEGTTVGAIRTGLVVLVGISKSDTIKDADYLADKVLGLRIFPDNEGKMNRNVAEAHGAILIISQFT
LYGDCRRGRRPSFDAAAAPGEALTLYNYFVDTVRKSPVPVETGTFQATMEVSLVNQGPVTIVIESEERNRK

Sequences:

>Translated_151_residues
MKLVIQRVSQAHVNVEGTTVGAIRTGLVVLVGISKSDTIKDADYLADKVLGLRIFPDNEGKMNRNVAEAHGAILIISQFT
LYGDCRRGRRPSFDAAAAPGEALTLYNYFVDTVRKSPVPVETGTFQATMEVSLVNQGPVTIVIESEERNRK
>Mature_151_residues
MKLVIQRVSQAHVNVEGTTVGAIRTGLVVLVGISKSDTIKDADYLADKVLGLRIFPDNEGKMNRNVAEAHGAILIISQFT
LYGDCRRGRRPSFDAAAAPGEALTLYNYFVDTVRKSPVPVETGTFQATMEVSLVNQGPVTIVIESEERNRK

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=41.6107382550336, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=50.6944444444444, Blast_Score=150, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=41.0596026490066, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=41.3333333333333, Blast_Score=117, Evalue=7e-28,
Organism=Drosophila melanogaster, GI281361569, Length=151, Percent_Identity=43.046357615894, Blast_Score=112, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_SOLUE (Q01RT2)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_827923.1
- ProteinModelPortal:   Q01RT2
- SMR:   Q01RT2
- STRING:   Q01RT2
- GeneID:   4425152
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_6717
- NMPDR:   fig|234267.9.peg.6388
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q01RT2
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16476; Mature: 16476

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVIQRVSQAHVNVEGTTVGAIRTGLVVLVGISKSDTIKDADYLADKVLGLRIFPDNEG
CHHHHHHHHHHEEECCCEEEHHECCCEEEEEECCCCCCCCHHHHHHHHHEEEEEEECCCC
KMNRNVAEAHGAILIISQFTLYGDCRRGRRPSFDAAAAPGEALTLYNYFVDTVRKSPVPV
CCCCCHHHHCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCC
ETGTFQATMEVSLVNQGPVTIVIESEERNRK
CCCCEEEEEEEEEECCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKLVIQRVSQAHVNVEGTTVGAIRTGLVVLVGISKSDTIKDADYLADKVLGLRIFPDNEG
CHHHHHHHHHHEEECCCEEEHHECCCEEEEEECCCCCCCCHHHHHHHHHEEEEEEECCCC
KMNRNVAEAHGAILIISQFTLYGDCRRGRRPSFDAAAAPGEALTLYNYFVDTVRKSPVPV
CCCCCHHHHCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCC
ETGTFQATMEVSLVNQGPVTIVIESEERNRK
CCCCEEEEEEEEEECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA