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The map label for this gene is acpS

Identifier: 116625762

GI number: 116625762

Start: 8414236

End: 8414613

Strand: Reverse

Name: acpS

Synonym: Acid_6712

Alternate gene names: 116625762

Gene position: 8414613-8414236 (Counterclockwise)

Preceding gene: 116625763

Following gene: 116625753

Centisome position: 84.44

GC content: 60.85

Gene sequence:

>378_bases
ATGATCGTCGGTACCGGAGTGGACCTCGCCGAAGTAGACCGCATTCAGAGATCGATCGAGCGCTATGGAGATAAGTTCAT
CAAGCGGATCTACACGCCCGGCGAGATCGCCTATGTAGAGCGCAAGGCCAATAAGTTCGAGCGATATGCGGCGCGCTTTG
CCGCCAAAGAAGCGGGTATGAAGGCCATCGGGACCGGTTGGCGCCACGGCGTCCGGTGGCAGGATTTCGAGGTCGCCAAC
TTACGCACCGGCAAGCCCACCCTGCTCCTCCACGGCGTCGCCGCCCGCTACGCCGAAAAGCTCGGCGTCAAGAATATCGC
CCTCTCCATCACCCACACGGCCGCGCTGGGAATGGCGCACGTCATCCTGGAAAACTAA

Upstream 100 bases:

>100_bases
GGCGTTCCGCCGACGTTCGCAAGGTGGCCGACGTCCTGATCAGCACCAAAGGTGTGAAGCACGGCCGCCTGACCATCACG
ACCACCGGAGCGGAGATGAA

Downstream 100 bases:

>100_bases
GTGCGCGTTTCAGAAGTTCGATCTCTTGTGCGCTAGCTCCGCCGCGCGCGCTCTTCCTTGTTCTCCGGCACCGCGCGCAG
TTGCGCGTCTTCCAGCAATT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MIVGTGVDLAEVDRIQRSIERYGDKFIKRIYTPGEIAYVERKANKFERYAARFAAKEAGMKAIGTGWRHGVRWQDFEVAN
LRTGKPTLLLHGVAARYAEKLGVKNIALSITHTAALGMAHVILEN

Sequences:

>Translated_125_residues
MIVGTGVDLAEVDRIQRSIERYGDKFIKRIYTPGEIAYVERKANKFERYAARFAAKEAGMKAIGTGWRHGVRWQDFEVAN
LRTGKPTLLLHGVAARYAEKLGVKNIALSITHTAALGMAHVILEN
>Mature_125_residues
MIVGTGVDLAEVDRIQRSIERYGDKFIKRIYTPGEIAYVERKANKFERYAARFAAKEAGMKAIGTGWRHGVRWQDFEVAN
LRTGKPTLLLHGVAARYAEKLGVKNIALSITHTAALGMAHVILEN

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=124, Percent_Identity=40.3225806451613, Blast_Score=86, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6325025, Length=110, Percent_Identity=33.6363636363636, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_SOLUE (Q01RT7)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_827918.1
- ProteinModelPortal:   Q01RT7
- SMR:   Q01RT7
- STRING:   Q01RT7
- GeneID:   4425147
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_6712
- NMPDR:   fig|234267.9.peg.6382
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   NSSAIAY
- PhylomeDB:   Q01RT7
- ProtClustDB:   PRK14660
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13955; Mature: 13955

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGTGVDLAEVDRIQRSIERYGDKFIKRIYTPGEIAYVERKANKFERYAARFAAKEAGM
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
KAIGTGWRHGVRWQDFEVANLRTGKPTLLLHGVAARYAEKLGVKNIALSITHTAALGMAH
HHHCCCCCCCCCCCCEEECCCCCCCCHHEEHHHHHHHHHHCCCCHHEEEHHHHHHHHHHH
VILEN
HHCCC
>Mature Secondary Structure
MIVGTGVDLAEVDRIQRSIERYGDKFIKRIYTPGEIAYVERKANKFERYAARFAAKEAGM
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
KAIGTGWRHGVRWQDFEVANLRTGKPTLLLHGVAARYAEKLGVKNIALSITHTAALGMAH
HHHCCCCCCCCCCCCEEECCCCCCCCHHEEHHHHHHHHHHCCCCHHEEEHHHHHHHHHHH
VILEN
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA