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The map label for this gene is regX3 [H]

Identifier: 116625746

GI number: 116625746

Start: 8399777

End: 8400484

Strand: Reverse

Name: regX3 [H]

Synonym: Acid_6696

Alternate gene names: 116625746

Gene position: 8400484-8399777 (Counterclockwise)

Preceding gene: 116625748

Following gene: 116625745

Centisome position: 84.29

GC content: 61.02

Gene sequence:

>708_bases
GTGTCGGATCGGCTACAATTTAAGTTGCCCCCCATGCAGACGATTCTCGTAATTGACGACGACGAGAGCCTGCGCGACAC
CATCGTCGTGATGTTGGAGCAGGAAGGTTTTCGCGCGGTCCAGGCCGGCGACGGACGCGATGGCTTTGAGAAAGCCATCA
CTACCAAGCCCGATCTGGTGCTGGTGGACCTACGCCTGCCCGGCATGAGCGGCACGGAGATCTGTAAGCAGCTGCGCGCC
GCGCGGGTTGCGACGCCCATTATCGTGCTTAGTGCGATGGATGACGAACTGGACAAAGTCCTGCTCCTCGAAATCGGTGC
TGACGATTACGTCGTCAAACCCTTCGGCACGCGCGAGCTCACGGCCCGCATTCGCGCCGTACTGCGGCGCGCCTCCACCG
ACGCGCGCAAGGTCATGCACTTCTCTGAAGTCGAGGTGGATTTCGAACGCCGCGTCGTCAAGCGCAAGGGCGAAGACCTT
AAGCTCACCCCCGCGGAATACAACCTGCTGACGTACTTCCTCCACAACCCCGACCGGCCCCTCACCCGCGACATGATCCT
GAATTCCGTGTGGGGGTACGAGTTCTTCCCCAACACCCGGACGGTGGACGCGCACGTTGTCAAACTACGCCAGAAGCTCG
AACCGGACCCGAACACCCCCAAGCACTTCCTGACTGTCCACGGCGTCGGCTACCGATTTATCCCGTGA

Upstream 100 bases:

>100_bases
CATAACCCGTTCCGATTACAGTGACTCTCATGGCGTGCGAGGCCCCCTGATTCCCCGTTTGCAAAGTATAACAAGGGCTG
TCAGCCGGACGCGGTCCGGA

Downstream 100 bases:

>100_bases
TTTATCCCCGCGACCGCCACCAACTAGCCGCGACCGTGAAGGAGCGCTAACCGCAGACCATCTGCCGTAACGCTCCCGGC
TCGTTGGGGAATCCCCGGAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSDRLQFKLPPMQTILVIDDDESLRDTIVVMLEQEGFRAVQAGDGRDGFEKAITTKPDLVLVDLRLPGMSGTEICKQLRA
ARVATPIIVLSAMDDELDKVLLLEIGADDYVVKPFGTRELTARIRAVLRRASTDARKVMHFSEVEVDFERRVVKRKGEDL
KLTPAEYNLLTYFLHNPDRPLTRDMILNSVWGYEFFPNTRTVDAHVVKLRQKLEPDPNTPKHFLTVHGVGYRFIP

Sequences:

>Translated_235_residues
MSDRLQFKLPPMQTILVIDDDESLRDTIVVMLEQEGFRAVQAGDGRDGFEKAITTKPDLVLVDLRLPGMSGTEICKQLRA
ARVATPIIVLSAMDDELDKVLLLEIGADDYVVKPFGTRELTARIRAVLRRASTDARKVMHFSEVEVDFERRVVKRKGEDL
KLTPAEYNLLTYFLHNPDRPLTRDMILNSVWGYEFFPNTRTVDAHVVKLRQKLEPDPNTPKHFLTVHGVGYRFIP
>Mature_234_residues
SDRLQFKLPPMQTILVIDDDESLRDTIVVMLEQEGFRAVQAGDGRDGFEKAITTKPDLVLVDLRLPGMSGTEICKQLRAA
RVATPIIVLSAMDDELDKVLLLEIGADDYVVKPFGTRELTARIRAVLRRASTDARKVMHFSEVEVDFERRVVKRKGEDLK
LTPAEYNLLTYFLHNPDRPLTRDMILNSVWGYEFFPNTRTVDAHVVKLRQKLEPDPNTPKHFLTVHGVGYRFIP

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=42.2222222222222, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=39.1891891891892, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=37.117903930131, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=37.0212765957447, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786784, Length=218, Percent_Identity=36.2385321100917, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=36.6515837104072, Blast_Score=136, Evalue=9e-34,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=33.4841628959276, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=34.841628959276, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789402, Length=217, Percent_Identity=35.0230414746544, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=31.6742081447964, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=31.8181818181818, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI2367329, Length=239, Percent_Identity=34.7280334728033, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=28.8135593220339, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=31.5555555555556, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788550, Length=136, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790299, Length=129, Percent_Identity=29.4573643410853, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790437, Length=122, Percent_Identity=32.7868852459016, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26832; Mature: 26701

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRLQFKLPPMQTILVIDDDESLRDTIVVMLEQEGFRAVQAGDGRDGFEKAITTKPDLV
CCCCEEEECCCCEEEEEEECCCCCCEEEEEEECCCCCEEEECCCCCCHHHHHHCCCCCEE
LVDLRLPGMSGTEICKQLRAARVATPIIVLSAMDDELDKVLLLEIGADDYVVKPFGTREL
EEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCEEECCCCCHHH
TARIRAVLRRASTDARKVMHFSEVEVDFERRVVKRKGEDLKLTPAEYNLLTYFLHNPDRP
HHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCEEEEEEEECCCCC
LTRDMILNSVWGYEFFPNTRTVDAHVVKLRQKLEPDPNTPKHFLTVHGVGYRFIP
HHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEECC
>Mature Secondary Structure 
SDRLQFKLPPMQTILVIDDDESLRDTIVVMLEQEGFRAVQAGDGRDGFEKAITTKPDLV
CCCEEEECCCCEEEEEEECCCCCCEEEEEEECCCCCEEEECCCCCCHHHHHHCCCCCEE
LVDLRLPGMSGTEICKQLRAARVATPIIVLSAMDDELDKVLLLEIGADDYVVKPFGTREL
EEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCEEECCCCCHHH
TARIRAVLRRASTDARKVMHFSEVEVDFERRVVKRKGEDLKLTPAEYNLLTYFLHNPDRP
HHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCEEEEEEEECCCCC
LTRDMILNSVWGYEFFPNTRTVDAHVVKLRQKLEPDPNTPKHFLTVHGVGYRFIP
HHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA