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The map label for this gene is ccpA [H]

Identifier: 116625713

GI number: 116625713

Start: 8364242

End: 8365252

Strand: Direct

Name: ccpA [H]

Synonym: Acid_6662

Alternate gene names: 116625713

Gene position: 8364242-8365252 (Clockwise)

Preceding gene: 116625711

Following gene: 116625714

Centisome position: 83.93

GC content: 63.4

Gene sequence:

>1011_bases
ATGGCAATAACTATCAAAGACGTTGCGCGCGAATCGGGAGTGAATGTGTCCACCGTCTCGCGCGCCTTGAATGGCGAGTA
CGGAGTCCACGCGGGCACCCGCGAGCACGTCCTGGCGATTGCCAAGCGCCTGCACTACCGCCCCAACCGCGTTGCCCGCG
GACTCGTGACCGGCCGATCCCACTCACTCGCCCTCGTCGTCAGCGACATCCGTAACCCCTTCTTCGCCGAAGTCGCCCGC
GGCGCCGAGGATGCCGCGTATGCCGCTGACTATGACCTAGTCCTCTGTAATAGCGATCTCGACGCCGAAAAGCAATTGCG
CTACGTCCAATCACTCATGGAGAAGCGCATCGACGGCATCCTGATGAACTCCGTCGCCGCGCTCAGCAAGAAGCAGGTCG
AGCAGCTTTCCGGCTTTGGCGTGCCTATCGTGCTGCTCAATCGCGCCGCTCCCCGCAATGCCTTCTCCACCATCTCCGCC
GACAACGACGCGGGCGGAGCCCTCGCCGGCGAGTATCTCTGGAAACTCGGCCATCGGAAGATCGCTCACCTCACCGGCCC
GCGACACCACGGCAACATGACCGAGCGCGCCGAAGGCTTCGTGCGCAGCCTCGCCGAAGCGCGCAAGCCCGTGCGGCCCG
TGATCCTGCACGGCAAGAATAATTTCCAGGGCGGCGTGGAACTCGCGGACAAACTCCTCGCGCTCCACCCGGACACCACC
GCCATCTTCGTCGCCAGCGACATGATGGCCTTCGGCGTGATCCGCGCGCTGATGGAGGCCGGCCGCCGCATTCCGGACGA
CGTCTCCGTGATCGGCTTCGACAACGTGGAGCTCTCTACGATCGTGAATCCCTCCCTCACCACCATTCACCAGCCCAAGT
ACGAAATCGGCCAGGCTGCCGTCGAAATTCTCCTCCGCCTCGCCGGCCGCGGCGAGCACCAGGCCCCGGAGCATCGCCTC
TTCGGTGTCCATCTCGTCGAAAGAAAAAGTTGTATGGAGCTCAAGTCATGA

Upstream 100 bases:

>100_bases
CTGCAAACGTTTCCAATATTCATTCGGGTATCCCGTCATTCCCGGTGGGTGTTTACTTTGCTCCCGCCAGATCCTATAAT
CAAAAACGTTTGCAACAATC

Downstream 100 bases:

>100_bases
TGAACCGCAGAGAACTCTTGCAGTCTGCCGGCCTCGCCCTTGCGTCGTCACGACTGCACGCGCAGCCGCAATCCAGCGAG
GTTTCCACGGCGGACTGGCT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MAITIKDVARESGVNVSTVSRALNGEYGVHAGTREHVLAIAKRLHYRPNRVARGLVTGRSHSLALVVSDIRNPFFAEVAR
GAEDAAYAADYDLVLCNSDLDAEKQLRYVQSLMEKRIDGILMNSVAALSKKQVEQLSGFGVPIVLLNRAAPRNAFSTISA
DNDAGGALAGEYLWKLGHRKIAHLTGPRHHGNMTERAEGFVRSLAEARKPVRPVILHGKNNFQGGVELADKLLALHPDTT
AIFVASDMMAFGVIRALMEAGRRIPDDVSVIGFDNVELSTIVNPSLTTIHQPKYEIGQAAVEILLRLAGRGEHQAPEHRL
FGVHLVERKSCMELKS

Sequences:

>Translated_336_residues
MAITIKDVARESGVNVSTVSRALNGEYGVHAGTREHVLAIAKRLHYRPNRVARGLVTGRSHSLALVVSDIRNPFFAEVAR
GAEDAAYAADYDLVLCNSDLDAEKQLRYVQSLMEKRIDGILMNSVAALSKKQVEQLSGFGVPIVLLNRAAPRNAFSTISA
DNDAGGALAGEYLWKLGHRKIAHLTGPRHHGNMTERAEGFVRSLAEARKPVRPVILHGKNNFQGGVELADKLLALHPDTT
AIFVASDMMAFGVIRALMEAGRRIPDDVSVIGFDNVELSTIVNPSLTTIHQPKYEIGQAAVEILLRLAGRGEHQAPEHRL
FGVHLVERKSCMELKS
>Mature_335_residues
AITIKDVARESGVNVSTVSRALNGEYGVHAGTREHVLAIAKRLHYRPNRVARGLVTGRSHSLALVVSDIRNPFFAEVARG
AEDAAYAADYDLVLCNSDLDAEKQLRYVQSLMEKRIDGILMNSVAALSKKQVEQLSGFGVPIVLLNRAAPRNAFSTISAD
NDAGGALAGEYLWKLGHRKIAHLTGPRHHGNMTERAEGFVRSLAEARKPVRPVILHGKNNFQGGVELADKLLALHPDTTA
IFVASDMMAFGVIRALMEAGRRIPDDVSVIGFDNVELSTIVNPSLTTIHQPKYEIGQAAVEILLRLAGRGEHQAPEHRLF
GVHLVERKSCMELKS

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=305, Percent_Identity=36.0655737704918, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=32.7272727272727, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787948, Length=331, Percent_Identity=33.8368580060423, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1788474, Length=329, Percent_Identity=32.5227963525836, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1787580, Length=334, Percent_Identity=29.3413173652695, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1789202, Length=297, Percent_Identity=30.6397306397306, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1789068, Length=336, Percent_Identity=29.1666666666667, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786540, Length=335, Percent_Identity=30.4477611940298, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1786268, Length=312, Percent_Identity=26.2820512820513, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790689, Length=316, Percent_Identity=29.1139240506329, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1787906, Length=305, Percent_Identity=27.5409836065574, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790715, Length=317, Percent_Identity=24.9211356466877, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI48994940, Length=322, Percent_Identity=25.1552795031056, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790192, Length=254, Percent_Identity=32.6771653543307, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789456, Length=320, Percent_Identity=26.875, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36657; Mature: 36525

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITIKDVARESGVNVSTVSRALNGEYGVHAGTREHVLAIAKRLHYRPNRVARGLVTGRS
CEEEHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCC
HSLALVVSDIRNPFFAEVARGAEDAAYAADYDLVLCNSDLDAEKQLRYVQSLMEKRIDGI
CCEEEEEHHHCCHHHHHHHCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LMNSVAALSKKQVEQLSGFGVPIVLLNRAAPRNAFSTISADNDAGGALAGEYLWKLGHRK
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCHH
IAHLTGPRHHGNMTERAEGFVRSLAEARKPVRPVILHGKNNFQGGVELADKLLALHPDTT
HHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCC
AIFVASDMMAFGVIRALMEAGRRIPDDVSVIGFDNVELSTIVNPSLTTIHQPKYEIGQAA
EEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEECCCCHHCCCCCHHHHHHHH
VEILLRLAGRGEHQAPEHRLFGVHLVERKSCMELKS
HHHHHHHHCCCCCCCCCHHEEEEHHHHHHHHHHCCC
>Mature Secondary Structure 
AITIKDVARESGVNVSTVSRALNGEYGVHAGTREHVLAIAKRLHYRPNRVARGLVTGRS
EEEHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCC
HSLALVVSDIRNPFFAEVARGAEDAAYAADYDLVLCNSDLDAEKQLRYVQSLMEKRIDGI
CCEEEEEHHHCCHHHHHHHCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LMNSVAALSKKQVEQLSGFGVPIVLLNRAAPRNAFSTISADNDAGGALAGEYLWKLGHRK
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCHH
IAHLTGPRHHGNMTERAEGFVRSLAEARKPVRPVILHGKNNFQGGVELADKLLALHPDTT
HHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCC
AIFVASDMMAFGVIRALMEAGRRIPDDVSVIGFDNVELSTIVNPSLTTIHQPKYEIGQAA
EEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEECCCCHHCCCCCHHHHHHHH
VEILLRLAGRGEHQAPEHRLFGVHLVERKSCMELKS
HHHHHHHHCCCCCCCCCHHEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]