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The map label for this gene is macB1 [H]

Identifier: 116625647

GI number: 116625647

Start: 8272787

End: 8275162

Strand: Reverse

Name: macB1 [H]

Synonym: Acid_6596

Alternate gene names: 116625647

Gene position: 8275162-8272787 (Counterclockwise)

Preceding gene: 116625650

Following gene: 116625646

Centisome position: 83.04

GC content: 68.1

Gene sequence:

>2376_bases
ATGCAGGACCTCCGCTACGCCCTCCGTGTCCTTTCCCGAGCCAAGGGATTCACGCTGGCCGCCGTGATCGTGCTCGCGCT
CGGCATCGGCGCGAACTCCGCCATCTTCAGCGTGGTGGATGCCGCCCTCCTGCGTCCGCTGCCCTACCACCGTCCTGGAG
AGATCGTGGTTCTCTGGGAACTCCCACCGAGCCGTATCAACAACCGCGTCTCCCCGCTCAACTTCGTGGACTGGCACGAT
CAAAACACGGTCTTCTCCTCCACCGCCGCCATCAGCGGCGGACCGCGTACCGTGACCGGACCTGGCGGAGCCGAACGTCT
TCCCGGCCAGGCCGTCACCAGCGAATTCTTCTCCCTCCTCGATGTGGCGCCCATCGCCGGCCGCACCTTCCGCGCCGAAG
ATGCTGCCGACAATCCCGATTCCGTCGTCATCAGCGAGCGCCTCTGGCGCAGCCGCTTCCACGCCGACCCCGCCCTGGTT
GGCCGCTCGATCGCGCTCGATGGCAAGCCTTTCACGCTGCTCGGCGTTGTCCCCGCCGCCTTCCAAATCTTCTATCCCAG
CGATCTTTGGACCCTCTACGTTCCCAAGCGCAGCCCCGAGCAGCGCCGCATGCATTACCTCCAGGTGATCGGCCGTCTCA
AGCCCGGCGTCTCGCTCGCACAGGCGCAGGCCGCAATGAACGGTGTCGCCGCGGGAATCGCGCGCATCTCACCCGAGACC
AACAGGAATTGGAGCATCGCACTCCAGCCGCTGCATCGCGCGCTGGTCGGCGAGGAACTGCGCAGCACCTCGCTCGTCCT
GGGAGCCGTAGTCTCCTTCGTTCTTCTGATGGCGTGCGCCAACGTCGCCAACCTGATGCTGGCTCGCGGATCGGCGCGCG
CTCGCGAAATCGCGGTCCGCGTCTCGCTCGGCGCGGTCCGCGCGCAACTCGCGCGCCAGTTGCTCACCGAGAGTGTGCTG
CTCGCCGTGCTCGGCGGCGCCTTTGGCCTGTGTCTCGCGTGGCTGCTCATCCGCCTTGCCCCGCGCCTGATTCCTCCCGA
CGCGCTTCCCGCCGGCGTGGCGCTCGCGCTCGATGTCCGCGTGTTCGCATTCGCCGTCCTCGCCACTTTTGCCTGCGGCA
TCCTCTTCGGTCTCGCCCCCGCCTGGCAGGCCTCCCGCGCCGCGCTTTCCACCGGAATGCGCGCGTCCGCCGGCGCCGGC
AGCGCCCGGATGCTGAACTCCGTCGCGATGGTGCAGATTGCGATCGCGGTCATCATCGTCACCGGCGCGGGTCTCTTCCT
CCGCACGCTCGACCGGCTCACGCAGGTCGATTCCGGCTATCACGCCGACCACGTTCTCACGGCGAATGTGATTCTCCCGC
TCACCCGCTATCCCAACCCGGACCGCGCGCTCCTCTTCTATCAGACCGCGCAGCGCGAACTGGAAACGCTGCCCGGCGTG
CGCGCTGCTTCATTCGGCGGCAGCCTGCCGCTTACCGGCTTCGACATCGGCCAGGGCTTCCGCGCCGGCGACGAAAAGGG
CTCGGCGCACTACCAGATCGTCGGCGCGCGCTACTTCGAAGCCCTCGGCATCCCGCTGGAAGCGGGCCGCGCCTTCGAGC
TTCGCGACACCGCCGCCGCGCCGCAGGTCGCCATCGTCAACCGCGAAATGGTGCGCCGCTACTTCAACGGCCGGTCGCCG
ATCGGCCGGCACATCGAAGTCTCCGCCATGGATCCCGCGGGTCCGCGCCTCATCGACCGCGAAATCGTCGGCGTCGCCGG
ACAGGTGAAGGTCGCCAGTCCCGGAGAAGCCGAGAACGTTGCGGAGATCTATGTGCCGATCACGCAGAACCCGTGGTTCT
CGGCTTCCATCGCGCTGCGCGCCACTGGCGATCCGGTTGCACTCGCCGCGGCGCTCAAGGCGGCCATTGCCAAGATTGAC
AAGGATCTCGCCGTGACCCATATCCGCAGCATGGACGAAATCGCCGCCGCGTCCGTAGCGCGCCCGCGCTTCCGCGCTCA
ATTGCTGGGCGCCTTTGCACTACTCTCGCTCGTGCTCTCGGCCGTCGGCGTTTTCGCCGTGCTCGCCTATTCAGTCGCAC
AGCGCAAGCGCGAATTCGGCATCCGCATGGCCCTCGGCGCGCAGATCGCCGACGTGCTTTCCCTGGTCCTCACTCGCGGA
CTGAAGATCGCTGTCACCGGAGTCGCCGCCGGACTGCTCGGAGCCGCTCTCCTGGCGCGCAGCCTCGCCACGCTCCTCTA
TGGCGTGCAGCCGCTCGACCCCGGAACCTTCGGCGCCACCTCCGCCCTGCTCGCGATCATCGCGCTCGCCGCCGCTGCCA
TCCCCGCCTGGCGCGCCGCCCGCACCGACCCGGCCATCGCCTTGCGCGATGAATAG

Upstream 100 bases:

>100_bases
AGCAACAGGTTGGCCAACGTCAGCAGTCCGGCGAGCGTATGAATCCGCGCAATCAATTCCACCAGCCTAACCCGGACCCA
TCGCCGCCGTCCAACCGTCC

Downstream 100 bases:

>100_bases
CGCTGGTCAACAAGCCGCGACCGTCAGCGAGCAATCGCAACGCCAAGAGGATTGAAGCACCCTCCGACGTTAAGGCTGCT
GTAACGATTCACGAAGAGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 791; Mature: 791

Protein sequence:

>791_residues
MQDLRYALRVLSRAKGFTLAAVIVLALGIGANSAIFSVVDAALLRPLPYHRPGEIVVLWELPPSRINNRVSPLNFVDWHD
QNTVFSSTAAISGGPRTVTGPGGAERLPGQAVTSEFFSLLDVAPIAGRTFRAEDAADNPDSVVISERLWRSRFHADPALV
GRSIALDGKPFTLLGVVPAAFQIFYPSDLWTLYVPKRSPEQRRMHYLQVIGRLKPGVSLAQAQAAMNGVAAGIARISPET
NRNWSIALQPLHRALVGEELRSTSLVLGAVVSFVLLMACANVANLMLARGSARAREIAVRVSLGAVRAQLARQLLTESVL
LAVLGGAFGLCLAWLLIRLAPRLIPPDALPAGVALALDVRVFAFAVLATFACGILFGLAPAWQASRAALSTGMRASAGAG
SARMLNSVAMVQIAIAVIIVTGAGLFLRTLDRLTQVDSGYHADHVLTANVILPLTRYPNPDRALLFYQTAQRELETLPGV
RAASFGGSLPLTGFDIGQGFRAGDEKGSAHYQIVGARYFEALGIPLEAGRAFELRDTAAAPQVAIVNREMVRRYFNGRSP
IGRHIEVSAMDPAGPRLIDREIVGVAGQVKVASPGEAENVAEIYVPITQNPWFSASIALRATGDPVALAAALKAAIAKID
KDLAVTHIRSMDEIAAASVARPRFRAQLLGAFALLSLVLSAVGVFAVLAYSVAQRKREFGIRMALGAQIADVLSLVLTRG
LKIAVTGVAAGLLGAALLARSLATLLYGVQPLDPGTFGATSALLAIIALAAAAIPAWRAARTDPAIALRDE

Sequences:

>Translated_791_residues
MQDLRYALRVLSRAKGFTLAAVIVLALGIGANSAIFSVVDAALLRPLPYHRPGEIVVLWELPPSRINNRVSPLNFVDWHD
QNTVFSSTAAISGGPRTVTGPGGAERLPGQAVTSEFFSLLDVAPIAGRTFRAEDAADNPDSVVISERLWRSRFHADPALV
GRSIALDGKPFTLLGVVPAAFQIFYPSDLWTLYVPKRSPEQRRMHYLQVIGRLKPGVSLAQAQAAMNGVAAGIARISPET
NRNWSIALQPLHRALVGEELRSTSLVLGAVVSFVLLMACANVANLMLARGSARAREIAVRVSLGAVRAQLARQLLTESVL
LAVLGGAFGLCLAWLLIRLAPRLIPPDALPAGVALALDVRVFAFAVLATFACGILFGLAPAWQASRAALSTGMRASAGAG
SARMLNSVAMVQIAIAVIIVTGAGLFLRTLDRLTQVDSGYHADHVLTANVILPLTRYPNPDRALLFYQTAQRELETLPGV
RAASFGGSLPLTGFDIGQGFRAGDEKGSAHYQIVGARYFEALGIPLEAGRAFELRDTAAAPQVAIVNREMVRRYFNGRSP
IGRHIEVSAMDPAGPRLIDREIVGVAGQVKVASPGEAENVAEIYVPITQNPWFSASIALRATGDPVALAAALKAAIAKID
KDLAVTHIRSMDEIAAASVARPRFRAQLLGAFALLSLVLSAVGVFAVLAYSVAQRKREFGIRMALGAQIADVLSLVLTRG
LKIAVTGVAAGLLGAALLARSLATLLYGVQPLDPGTFGATSALLAIIALAAAAIPAWRAARTDPAIALRDE
>Mature_791_residues
MQDLRYALRVLSRAKGFTLAAVIVLALGIGANSAIFSVVDAALLRPLPYHRPGEIVVLWELPPSRINNRVSPLNFVDWHD
QNTVFSSTAAISGGPRTVTGPGGAERLPGQAVTSEFFSLLDVAPIAGRTFRAEDAADNPDSVVISERLWRSRFHADPALV
GRSIALDGKPFTLLGVVPAAFQIFYPSDLWTLYVPKRSPEQRRMHYLQVIGRLKPGVSLAQAQAAMNGVAAGIARISPET
NRNWSIALQPLHRALVGEELRSTSLVLGAVVSFVLLMACANVANLMLARGSARAREIAVRVSLGAVRAQLARQLLTESVL
LAVLGGAFGLCLAWLLIRLAPRLIPPDALPAGVALALDVRVFAFAVLATFACGILFGLAPAWQASRAALSTGMRASAGAG
SARMLNSVAMVQIAIAVIIVTGAGLFLRTLDRLTQVDSGYHADHVLTANVILPLTRYPNPDRALLFYQTAQRELETLPGV
RAASFGGSLPLTGFDIGQGFRAGDEKGSAHYQIVGARYFEALGIPLEAGRAFELRDTAAAPQVAIVNREMVRRYFNGRSP
IGRHIEVSAMDPAGPRLIDREIVGVAGQVKVASPGEAENVAEIYVPITQNPWFSASIALRATGDPVALAAALKAAIAKID
KDLAVTHIRSMDEIAAASVARPRFRAQLLGAFALLSLVLSAVGVFAVLAYSVAQRKREFGIRMALGAQIADVLSLVLTRG
LKIAVTGVAAGLLGAALLARSLATLLYGVQPLDPGTFGATSALLAIIALAAAAIPAWRAARTDPAIALRDE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=282, Percent_Identity=26.241134751773, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 83708; Mature: 83708

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLRYALRVLSRAKGFTLAAVIVLALGIGANSAIFSVVDAALLRPLPYHRPGEIVVLWE
CCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEC
LPPSRINNRVSPLNFVDWHDQNTVFSSTAAISGGPRTVTGPGGAERLPGQAVTSEFFSLL
CCHHHHCCCCCCCCEEEECCCCCEEECCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHH
DVAPIAGRTFRAEDAADNPDSVVISERLWRSRFHADPALVGRSIALDGKPFTLLGVVPAA
HHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCEEEECCCCEEEEEEHHHH
FQIFYPSDLWTLYVPKRSPEQRRMHYLQVIGRLKPGVSLAQAQAAMNGVAAGIARISPET
HEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
NRNWSIALQPLHRALVGEELRSTSLVLGAVVSFVLLMACANVANLMLARGSARAREIAVR
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEE
VSLGAVRAQLARQLLTESVLLAVLGGAFGLCLAWLLIRLAPRLIPPDALPAGVALALDVR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VFAFAVLATFACGILFGLAPAWQASRAALSTGMRASAGAGSARMLNSVAMVQIAIAVIIV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TGAGLFLRTLDRLTQVDSGYHADHVLTANVILPLTRYPNPDRALLFYQTAQRELETLPGV
HCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEHHHHHHHHHCCCC
RAASFGGSLPLTGFDIGQGFRAGDEKGSAHYQIVGARYFEALGIPLEAGRAFELRDTAAA
EECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCEEEECCCCCC
PQVAIVNREMVRRYFNGRSPIGRHIEVSAMDPAGPRLIDREIVGVAGQVKVASPGEAENV
CCEEHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEECCCCCCCCE
AEIYVPITQNPWFSASIALRATGDPVALAAALKAAIAKIDKDLAVTHIRSMDEIAAASVA
EEEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPRFRAQLLGAFALLSLVLSAVGVFAVLAYSVAQRKREFGIRMALGAQIADVLSLVLTRG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
LKIAVTGVAAGLLGAALLARSLATLLYGVQPLDPGTFGATSALLAIIALAAAAIPAWRAA
CEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
RTDPAIALRDE
CCCCCEEECCC
>Mature Secondary Structure
MQDLRYALRVLSRAKGFTLAAVIVLALGIGANSAIFSVVDAALLRPLPYHRPGEIVVLWE
CCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEC
LPPSRINNRVSPLNFVDWHDQNTVFSSTAAISGGPRTVTGPGGAERLPGQAVTSEFFSLL
CCHHHHCCCCCCCCEEEECCCCCEEECCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHH
DVAPIAGRTFRAEDAADNPDSVVISERLWRSRFHADPALVGRSIALDGKPFTLLGVVPAA
HHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCEEEECCCCEEEEEEHHHH
FQIFYPSDLWTLYVPKRSPEQRRMHYLQVIGRLKPGVSLAQAQAAMNGVAAGIARISPET
HEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
NRNWSIALQPLHRALVGEELRSTSLVLGAVVSFVLLMACANVANLMLARGSARAREIAVR
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEE
VSLGAVRAQLARQLLTESVLLAVLGGAFGLCLAWLLIRLAPRLIPPDALPAGVALALDVR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VFAFAVLATFACGILFGLAPAWQASRAALSTGMRASAGAGSARMLNSVAMVQIAIAVIIV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TGAGLFLRTLDRLTQVDSGYHADHVLTANVILPLTRYPNPDRALLFYQTAQRELETLPGV
HCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEHHHHHHHHHCCCC
RAASFGGSLPLTGFDIGQGFRAGDEKGSAHYQIVGARYFEALGIPLEAGRAFELRDTAAA
EECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCEEEECCCCCC
PQVAIVNREMVRRYFNGRSPIGRHIEVSAMDPAGPRLIDREIVGVAGQVKVASPGEAENV
CCEEHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEECCCCCCCCE
AEIYVPITQNPWFSASIALRATGDPVALAAALKAAIAKIDKDLAVTHIRSMDEIAAASVA
EEEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPRFRAQLLGAFALLSLVLSAVGVFAVLAYSVAQRKREFGIRMALGAQIADVLSLVLTRG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
LKIAVTGVAAGLLGAALLARSLATLLYGVQPLDPGTFGATSALLAIIALAAAAIPAWRAA
CEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
RTDPAIALRDE
CCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA