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The map label for this gene is macB [H]

Identifier: 116625622

GI number: 116625622

Start: 8235391

End: 8235864

Strand: Direct

Name: macB [H]

Synonym: Acid_6571

Alternate gene names: 116625622

Gene position: 8235391-8235864 (Clockwise)

Preceding gene: 116625621

Following gene: 116625628

Centisome position: 82.64

GC content: 68.78

Gene sequence:

>474_bases
ATGGTGGCGGCGGTGGATCGCGATCAGCCCGTCACCAACCTACGCACGATGGATGAAGTGGTTCGGAATGCGCTCTCGCA
GCGCCGCGAGACAATGTACCTGATCGCCGCCTTCGCGGCGGTCGCCCTGATTCTCGCGGTCATCGGCCTTTACGGCGTGA
TGGCGTACTCGGTGGCGCAGCGCACGGCCGAGATCGGCATCCGCCAGGCGATCGGCGCGCAGCGCGGCGACATCGTGCGG
ATGGTTCTGGCCGAGGGCATGCGGCTCAGCGCCTTGGGCATCGCGATCGGAGTGATCGCGGCCATCGGGTTCACCAGGCT
GCTGGGCCGCCTGCTGTTCCACGTAAGCGCGACGGACCCGGCGACCTTCGCGGCAATCGCCGGGCTCTTCCTGGCGGTAT
CTCTCGCCGCCTGCGCGCTGCCTGCCCGTCGAGCCACGCGGATCGACCCGCTCGAGGCGCTGCGGACAAGGTAG

Upstream 100 bases:

>100_bases
GGCGATCTTCACTGCCTACCCGCAGTGGACCTGGCAGAGCGTATCGCTCACCGTGCGCACCGATGGCGATCCGCGGCCGC
TGAGCAAGGCGCTCAGCGCG

Downstream 100 bases:

>100_bases
CCCAGAATCTACCAACCGCTTGCTCACGGGTCTGTGAAAAAATCCCGATCTGCATCGAGCTTCGCTCGACTGCGCGCAAG
CTATAGCGTGCGCCACAAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MVAAVDRDQPVTNLRTMDEVVRNALSQRRETMYLIAAFAAVALILAVIGLYGVMAYSVAQRTAEIGIRQAIGAQRGDIVR
MVLAEGMRLSALGIAIGVIAAIGFTRLLGRLLFHVSATDPATFAAIAGLFLAVSLAACALPARRATRIDPLEALRTR

Sequences:

>Translated_157_residues
MVAAVDRDQPVTNLRTMDEVVRNALSQRRETMYLIAAFAAVALILAVIGLYGVMAYSVAQRTAEIGIRQAIGAQRGDIVR
MVLAEGMRLSALGIAIGVIAAIGFTRLLGRLLFHVSATDPATFAAIAGLFLAVSLAACALPARRATRIDPLEALRTR
>Mature_157_residues
MVAAVDRDQPVTNLRTMDEVVRNALSQRRETMYLIAAFAAVALILAVIGLYGVMAYSVAQRTAEIGIRQAIGAQRGDIVR
MVLAEGMRLSALGIAIGVIAAIGFTRLLGRLLFHVSATDPATFAAIAGLFLAVSLAACALPARRATRIDPLEALRTR

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=144, Percent_Identity=31.25, Blast_Score=60, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 16705; Mature: 16705

Theoretical pI: Translated: 11.36; Mature: 11.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAAVDRDQPVTNLRTMDEVVRNALSQRRETMYLIAAFAAVALILAVIGLYGVMAYSVAQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTAEIGIRQAIGAQRGDIVRMVLAEGMRLSALGIAIGVIAAIGFTRLLGRLLFHVSATDP
HHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ATFAAIAGLFLAVSLAACALPARRATRIDPLEALRTR
HHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHCC
>Mature Secondary Structure
MVAAVDRDQPVTNLRTMDEVVRNALSQRRETMYLIAAFAAVALILAVIGLYGVMAYSVAQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTAEIGIRQAIGAQRGDIVRMVLAEGMRLSALGIAIGVIAAIGFTRLLGRLLFHVSATDP
HHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ATFAAIAGLFLAVSLAACALPARRATRIDPLEALRTR
HHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA