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The map label for this gene is macB [H]

Identifier: 116625621

GI number: 116625621

Start: 8233442

End: 8235373

Strand: Direct

Name: macB [H]

Synonym: Acid_6570

Alternate gene names: 116625621

Gene position: 8233442-8235373 (Clockwise)

Preceding gene: 116625620

Following gene: 116625622

Centisome position: 82.62

GC content: 67.44

Gene sequence:

>1932_bases
ATGCGGCAGAACCTGCGATTCGCGCTCCGGATGATGATCAAGAGCCCTGGCTTCACCGCCGTCGCGGTACTCACGCTGGG
TCTCGGGATCGGCGCGAACACCGCAATTTTCAGTGTGGTGAACGCCCTGGTGCTGCGACCGCTGCCGCTAAGCGATCCCG
AGCGGCTGATGCTGATCTCGGTATCGAACCCGGCGCGCGGCTTTCGCGGCAGCTCGTTTTCGCTGGCATCCTTCGAGAGC
CTGCGCGACAAAAACCGGAGCTTCTCGGGAATCGCCGGTTTCTGCTTCGACGCGCTCACGCTGATCGGCGCAGCGGAGCC
CGAGCAGCTCGCCGCGGCGCGTGTCTCGCCCAACTTCTTCGACGTGCTCGGCACGCCGCCGCTGATCGGCCGCGGCTTCC
GGACCGCGGAAGGTGAGGCTGGCGCCGCGCCGGTCGCGCTGATCAGCTCCGCCCTCTGGCAGCGTCGCTACGCGGGCGAT
CGCGCGATTCTCGGCAAGACCATCTCACTGGACCAGGACGTCTACACGATCATCGGCGTGATGCCCGCCGACTACGCCTT
CCCTTCCCCGGGCCAGGACGTGTGGGTGACAAGGATCATGAAGTACGGGCGGCTGCAGCCGGAGCAGATACAGCAGGGCG
CCGGATTTCTGAACGCGATGGCGCGCCTGGCGCCGGGCGCAACCATTCCGGGGGCCGATGCCGAAGTCGCGATGATCACC
CGGCAATATCGCGCCGATCACCCGCGCGCGCCCGATGCCGACCCCAACGCACATCTGGACGTCGCGCCGCTGCAGGACAG
CCTGACCCTGCAGATCCGCCCGACGCTATTGGTCCTCACCGGCGCCGTTGGCTTCGTGCTGCTGATCGCCTGCGCCAACG
TGGCCGGCCTGATGATGGCGCGCGCCACCGGCCGGGCCAAGGAGATCGCGGTCCGCGCCGCGCTGGGAGCGAGCCGCGCG
CAACTCGTCCGCCAACTGCTTGCCGAAAGCATCGTGCTCGCCGCGGCCGGCGCGCTCCTGGGCGTACTGCTGGCCTCGTG
GGGAGTCGAGTGGCTGGTGAAGGCGGATGCCGGCAACAATCTGCCGGGCTTCCAACCGATTCGCGTCGATCTCGCGGTGC
TGGGTTTCACCGTCCTGGTCTCGATGATCACGGGCGTGGTGTTCGGCCTCGTGCCGGCGATGGAGGCATCGCGTCCGAAC
CTCATCGGCGTCCTGCGCGACGGTGGCTGGGGTACCACCGGCGGCGGTCGGGGCCGGCGCTTGCGAAATCTGATGGTCGC
GGGACAAATGGGACTCTCGATCGTCCTGCTGATCGGCGCCGGACTGCTGCTCGAGAGTTTTCGCCAGGTGCAAAACGTGA
AGCTCGGCTTCGACGCGCTCCACACGTTAACCGCGCGGATGGCGATCCCGCCGGCCAAGTATCCCGACGGGCCGGCGCGC
TCCCGCTTCGTCCACGAGATTGAGCAGCGCCTGCGAGGTATTCCGGGCGTGACCGCGGCGGCCATATCGCAATCCGTGCC
GCTCGGCCCGGTGATCCTCTCGCCGATTCTGGTCGAAGGCCAGCCCGTGGTACCGATGGGGCAGCGGCCGCTGGCGCAAT
GGGGAGGCGCCACGCCGGATTATTTCCGCACCCTCGCAATCCCGCTCGTGCGCGGCCGCTACTTCACCTGGGCCGACGAC
GCCCAGGCGCCGCGCGTCCTGATCGTCAATGAGGCGCTGGCGCGGCATTTCTGGCCAAATCAAAGCGCGCTCGGCAAGCA
CATTACATTACGCGATTTCAGTCGCCGTTTGAAATCGTCGGCGTGGTCGGCGACACCAAATCGCGCGGACTGGAAGTCGA
GACGCCGATGGCGATCTTCACTGCCTACCCGCAGTGGACCTGGCAGAGCGTATCGCTCACCGTGCGCACCGATGGCGATC
CGCGGCCGCTGA

Upstream 100 bases:

>100_bases
TGCCGAGGTCTCGCTCGCGGCGACGCGCCCGGTGAAGATCCTGCTGAACGCCGGCAGGAAGTAGGCCTAACCTTCCCACC
CGGATTGCGTCGGAGTAGGA

Downstream 100 bases:

>100_bases
GCAAGGCGCTCAGCGCGATGGTGGCGGCGGTGGATCGCGATCAGCCCGTCACCAACCTACGCACGATGGATGAAGTGGTT
CGGAATGCGCTCTCGCAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MRQNLRFALRMMIKSPGFTAVAVLTLGLGIGANTAIFSVVNALVLRPLPLSDPERLMLISVSNPARGFRGSSFSLASFES
LRDKNRSFSGIAGFCFDALTLIGAAEPEQLAAARVSPNFFDVLGTPPLIGRGFRTAEGEAGAAPVALISSALWQRRYAGD
RAILGKTISLDQDVYTIIGVMPADYAFPSPGQDVWVTRIMKYGRLQPEQIQQGAGFLNAMARLAPGATIPGADAEVAMIT
RQYRADHPRAPDADPNAHLDVAPLQDSLTLQIRPTLLVLTGAVGFVLLIACANVAGLMMARATGRAKEIAVRAALGASRA
QLVRQLLAESIVLAAAGALLGVLLASWGVEWLVKADAGNNLPGFQPIRVDLAVLGFTVLVSMITGVVFGLVPAMEASRPN
LIGVLRDGGWGTTGGGRGRRLRNLMVAGQMGLSIVLLIGAGLLLESFRQVQNVKLGFDALHTLTARMAIPPAKYPDGPAR
SRFVHEIEQRLRGIPGVTAAAISQSVPLGPVILSPILVEGQPVVPMGQRPLAQWGGATPDYFRTLAIPLVRGRYFTWADD
AQAPRVLIVNEALARHFWPNQSALGKHITLRDFSRRLKSSAWSATPNRADWKSRRRWRSSLPTRSGPGRAYRSPCAPMAI
RGR

Sequences:

>Translated_643_residues
MRQNLRFALRMMIKSPGFTAVAVLTLGLGIGANTAIFSVVNALVLRPLPLSDPERLMLISVSNPARGFRGSSFSLASFES
LRDKNRSFSGIAGFCFDALTLIGAAEPEQLAAARVSPNFFDVLGTPPLIGRGFRTAEGEAGAAPVALISSALWQRRYAGD
RAILGKTISLDQDVYTIIGVMPADYAFPSPGQDVWVTRIMKYGRLQPEQIQQGAGFLNAMARLAPGATIPGADAEVAMIT
RQYRADHPRAPDADPNAHLDVAPLQDSLTLQIRPTLLVLTGAVGFVLLIACANVAGLMMARATGRAKEIAVRAALGASRA
QLVRQLLAESIVLAAAGALLGVLLASWGVEWLVKADAGNNLPGFQPIRVDLAVLGFTVLVSMITGVVFGLVPAMEASRPN
LIGVLRDGGWGTTGGGRGRRLRNLMVAGQMGLSIVLLIGAGLLLESFRQVQNVKLGFDALHTLTARMAIPPAKYPDGPAR
SRFVHEIEQRLRGIPGVTAAAISQSVPLGPVILSPILVEGQPVVPMGQRPLAQWGGATPDYFRTLAIPLVRGRYFTWADD
AQAPRVLIVNEALARHFWPNQSALGKHITLRDFSRRLKSSAWSATPNRADWKSRRRWRSSLPTRSGPGRAYRSPCAPMAI
RGR
>Mature_643_residues
MRQNLRFALRMMIKSPGFTAVAVLTLGLGIGANTAIFSVVNALVLRPLPLSDPERLMLISVSNPARGFRGSSFSLASFES
LRDKNRSFSGIAGFCFDALTLIGAAEPEQLAAARVSPNFFDVLGTPPLIGRGFRTAEGEAGAAPVALISSALWQRRYAGD
RAILGKTISLDQDVYTIIGVMPADYAFPSPGQDVWVTRIMKYGRLQPEQIQQGAGFLNAMARLAPGATIPGADAEVAMIT
RQYRADHPRAPDADPNAHLDVAPLQDSLTLQIRPTLLVLTGAVGFVLLIACANVAGLMMARATGRAKEIAVRAALGASRA
QLVRQLLAESIVLAAAGALLGVLLASWGVEWLVKADAGNNLPGFQPIRVDLAVLGFTVLVSMITGVVFGLVPAMEASRPN
LIGVLRDGGWGTTGGGRGRRLRNLMVAGQMGLSIVLLIGAGLLLESFRQVQNVKLGFDALHTLTARMAIPPAKYPDGPAR
SRFVHEIEQRLRGIPGVTAAAISQSVPLGPVILSPILVEGQPVVPMGQRPLAQWGGATPDYFRTLAIPLVRGRYFTWADD
AQAPRVLIVNEALARHFWPNQSALGKHITLRDFSRRLKSSAWSATPNRADWKSRRRWRSSLPTRSGPGRAYRSPCAPMAI
RGR

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 68885; Mature: 68885

Theoretical pI: Translated: 11.55; Mature: 11.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQNLRFALRMMIKSPGFTAVAVLTLGLGIGANTAIFSVVNALVLRPLPLSDPERLMLIS
CCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEE
VSNPARGFRGSSFSLASFESLRDKNRSFSGIAGFCFDALTLIGAAEPEQLAAARVSPNFF
ECCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHH
DVLGTPPLIGRGFRTAEGEAGAAPVALISSALWQRRYAGDRAILGKTISLDQDVYTIIGV
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCEECCCCHHHHHHCC
MPADYAFPSPGQDVWVTRIMKYGRLQPEQIQQGAGFLNAMARLAPGATIPGADAEVAMIT
CCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
RQYRADHPRAPDADPNAHLDVAPLQDSLTLQIRPTLLVLTGAVGFVLLIACANVAGLMMA
HHHHCCCCCCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
RATGRAKEIAVRAALGASRAQLVRQLLAESIVLAAAGALLGVLLASWGVEWLVKADAGNN
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
LPGFQPIRVDLAVLGFTVLVSMITGVVFGLVPAMEASRPNLIGVLRDGGWGTTGGGRGRR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHH
LRNLMVAGQMGLSIVLLIGAGLLLESFRQVQNVKLGFDALHTLTARMAIPPAKYPDGPAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
SRFVHEIEQRLRGIPGVTAAAISQSVPLGPVILSPILVEGQPVVPMGQRPLAQWGGATPD
HHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHEECCCCCCCCCCCCHHHHCCCCHH
YFRTLAIPLVRGRYFTWADDAQAPRVLIVNEALARHFWPNQSALGKHITLRDFSRRLKSS
HHHHHHHHHHCCCEEEECCCCCCCEEEEEEHHHHHHCCCCCHHHCCCCHHHHHHHHHHHH
AWSATPNRADWKSRRRWRSSLPTRSGPGRAYRSPCAPMAIRGR
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRQNLRFALRMMIKSPGFTAVAVLTLGLGIGANTAIFSVVNALVLRPLPLSDPERLMLIS
CCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEE
VSNPARGFRGSSFSLASFESLRDKNRSFSGIAGFCFDALTLIGAAEPEQLAAARVSPNFF
ECCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHH
DVLGTPPLIGRGFRTAEGEAGAAPVALISSALWQRRYAGDRAILGKTISLDQDVYTIIGV
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCEECCCCHHHHHHCC
MPADYAFPSPGQDVWVTRIMKYGRLQPEQIQQGAGFLNAMARLAPGATIPGADAEVAMIT
CCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
RQYRADHPRAPDADPNAHLDVAPLQDSLTLQIRPTLLVLTGAVGFVLLIACANVAGLMMA
HHHHCCCCCCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
RATGRAKEIAVRAALGASRAQLVRQLLAESIVLAAAGALLGVLLASWGVEWLVKADAGNN
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
LPGFQPIRVDLAVLGFTVLVSMITGVVFGLVPAMEASRPNLIGVLRDGGWGTTGGGRGRR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHH
LRNLMVAGQMGLSIVLLIGAGLLLESFRQVQNVKLGFDALHTLTARMAIPPAKYPDGPAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
SRFVHEIEQRLRGIPGVTAAAISQSVPLGPVILSPILVEGQPVVPMGQRPLAQWGGATPD
HHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHEECCCCCCCCCCCCHHHHCCCCHH
YFRTLAIPLVRGRYFTWADDAQAPRVLIVNEALARHFWPNQSALGKHITLRDFSRRLKSS
HHHHHHHHHHCCCEEEECCCCCCCEEEEEEHHHHHHCCCCCHHHCCCCHHHHHHHHHHHH
AWSATPNRADWKSRRRWRSSLPTRSGPGRAYRSPCAPMAIRGR
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA