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The map label for this gene is iolE [H]

Identifier: 116625586

GI number: 116625586

Start: 8193707

End: 8194588

Strand: Direct

Name: iolE [H]

Synonym: Acid_6535

Alternate gene names: 116625586

Gene position: 8193707-8194588 (Clockwise)

Preceding gene: 116625585

Following gene: 116625587

Centisome position: 82.22

GC content: 58.96

Gene sequence:

>882_bases
ATGACCCGTCGCACTGCCCTTGCCCTTTTTGCGGCCACGCTCAGCCGGGCCGCGGGGAAGCTTCCCGCGAATAAGAATGT
GAAATGGGCGCTCGGCGCCAACCTGTGGAACTCCTTTCCGCGAGTGCCGTTCACGGACATTCTGGATGTCATGAAGGATA
CCGGGTTCATTGGCATCCGGATGACGCAGTTTCCGCAGATTCTGAAGACGTACAACGTCACGGTGCCGGAACTGCAGAAG
GAACTTTCCAAGCGCGGCTGCCAGATCATCACGATTTCGTTCAACGGTCCGACGCACGATCCGGCGAAGCGCGCGGACGT
GTTGGCGAGCGCGAAGACGGCGATGACGTTTCTCAAGGAGTTCGACGCGAAACACCTGGTGGTGTTTTCGCCGAACCGCA
GCAATGCCTCGGAGGCTGCCTTCAAGGCGATGTGTGAGTGCTTCAACGCGATCGGGGAAGCGGCGAACGAGATGGGTTTC
CGCGCCGGCCTGCACAATCACATGGGGCAGATCGTGCAGACCAGTGAAGAGGTGGACCGGTGCATGGCGATGACCGATTC
CAAGCTGTTTTCTTTCTCGCCGGATACGGCGCATCTGTATCTGGCGGATTGCGACGTGGTCAAGACCATCGACAAGCACA
AGAGCCGCCTGATGCTGCTGGATTACAAAGACGCGCGCATGAACAGCGACAAACTGCTCGACAATATTTTCGATCTCGGC
GATGGGGCGGTGGATTTTCCGGGCTGCCATCGCGTGCTGAAATCGATCGGGTTCAAGGGCTGGCTCTGTGTGGACCTGGA
CGTGGCGCGCAAGGGTCCGCGCGCGAGTTACGAGCGGTGCGCGGAGTACGTGGTCAACAAGCTGGAGCCAATTTATGTCT
GA

Upstream 100 bases:

>100_bases
CAGCAGTCTCGGGAGCGGCGGAGCGACTGGCGCGCACGGCGCGGGGCCGATCTAAGGGCGACTGGCATCTGGCGCGCGGC
GGGCGTAACATCAAGTGACT

Downstream 100 bases:

>100_bases
AGTAACTCGGCGAACGCTGCTCGCGGGGGCGGCGGCGAGCGGCATCGGGCTTGGGGCGCAGAGCAGGATACTGGATCCGC
ACGTGCATGTGTGGAAGCAC

Product: xylose isomerase domain-containing protein

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTRRTALALFAATLSRAAGKLPANKNVKWALGANLWNSFPRVPFTDILDVMKDTGFIGIRMTQFPQILKTYNVTVPELQK
ELSKRGCQIITISFNGPTHDPAKRADVLASAKTAMTFLKEFDAKHLVVFSPNRSNASEAAFKAMCECFNAIGEAANEMGF
RAGLHNHMGQIVQTSEEVDRCMAMTDSKLFSFSPDTAHLYLADCDVVKTIDKHKSRLMLLDYKDARMNSDKLLDNIFDLG
DGAVDFPGCHRVLKSIGFKGWLCVDLDVARKGPRASYERCAEYVVNKLEPIYV

Sequences:

>Translated_293_residues
MTRRTALALFAATLSRAAGKLPANKNVKWALGANLWNSFPRVPFTDILDVMKDTGFIGIRMTQFPQILKTYNVTVPELQK
ELSKRGCQIITISFNGPTHDPAKRADVLASAKTAMTFLKEFDAKHLVVFSPNRSNASEAAFKAMCECFNAIGEAANEMGF
RAGLHNHMGQIVQTSEEVDRCMAMTDSKLFSFSPDTAHLYLADCDVVKTIDKHKSRLMLLDYKDARMNSDKLLDNIFDLG
DGAVDFPGCHRVLKSIGFKGWLCVDLDVARKGPRASYERCAEYVVNKLEPIYV
>Mature_292_residues
TRRTALALFAATLSRAAGKLPANKNVKWALGANLWNSFPRVPFTDILDVMKDTGFIGIRMTQFPQILKTYNVTVPELQKE
LSKRGCQIITISFNGPTHDPAKRADVLASAKTAMTFLKEFDAKHLVVFSPNRSNASEAAFKAMCECFNAIGEAANEMGFR
AGLHNHMGQIVQTSEEVDRCMAMTDSKLFSFSPDTAHLYLADCDVVKTIDKHKSRLMLLDYKDARMNSDKLLDNIFDLGD
GAVDFPGCHRVLKSIGFKGWLCVDLDVARKGPRASYERCAEYVVNKLEPIYV

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 32640; Mature: 32509

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRTALALFAATLSRAAGKLPANKNVKWALGANLWNSFPRVPFTDILDVMKDTGFIGIR
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHCCCCCCHHHHHHHHHCCCCEEEE
MTQFPQILKTYNVTVPELQKELSKRGCQIITISFNGPTHDPAKRADVLASAKTAMTFLKE
HHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
FDAKHLVVFSPNRSNASEAAFKAMCECFNAIGEAANEMGFRAGLHNHMGQIVQTSEEVDR
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CMAMTDSKLFSFSPDTAHLYLADCDVVKTIDKHKSRLMLLDYKDARMNSDKLLDNIFDLG
HHHHHCCCCEEECCCCCEEEEECCHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHCC
DGAVDFPGCHRVLKSIGFKGWLCVDLDVARKGPRASYERCAEYVVNKLEPIYV
CCCCCCHHHHHHHHHCCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TRRTALALFAATLSRAAGKLPANKNVKWALGANLWNSFPRVPFTDILDVMKDTGFIGIR
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHCCCCCCHHHHHHHHHCCCCEEEE
MTQFPQILKTYNVTVPELQKELSKRGCQIITISFNGPTHDPAKRADVLASAKTAMTFLKE
HHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
FDAKHLVVFSPNRSNASEAAFKAMCECFNAIGEAANEMGFRAGLHNHMGQIVQTSEEVDR
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CMAMTDSKLFSFSPDTAHLYLADCDVVKTIDKHKSRLMLLDYKDARMNSDKLLDNIFDLG
HHHHHCCCCEEECCCCCEEEEECCHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHCC
DGAVDFPGCHRVLKSIGFKGWLCVDLDVARKGPRASYERCAEYVVNKLEPIYV
CCCCCCHHHHHHHHHCCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA