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The map label for this gene is yuxL [H]

Identifier: 116625575

GI number: 116625575

Start: 8177852

End: 8179810

Strand: Reverse

Name: yuxL [H]

Synonym: Acid_6523

Alternate gene names: 116625575

Gene position: 8179810-8177852 (Counterclockwise)

Preceding gene: 116625576

Following gene: 116625574

Centisome position: 82.08

GC content: 62.12

Gene sequence:

>1959_bases
ATGCGTTACGCACTTCTCCTCGCCTCCCTCCTCTGCGCCTCCGCTTTCGCGGCCGGCACCGTCCCCACCATCGACGAATC
TCTCGGCATGAAGTCTGTAGCCGGCGCCCAGATCTCCCCAGACGGCCGCTACGTCGCCTACACCGTTCAACAAGCCAACT
GGGACGAGAACGATTTCATCAGCCAGATCTGGATTGCCGTCACCGCCACCGGCGAGCGCTACCAGCTCACCAGCGGAAAG
AAATCCTCGACCGGCCCCCAATGGTCCCCCGATTCCCACCGCCTCGCCTTCACCAGCGATCGCGATGGCAAGCGCCAGAT
CTACCTCATCTCTCCCAATGGCGGTGAGGCCATCGCGCTAACCTCCGAAGAGAACGGCGTCTCCGCCATCGCATGGTCGC
CCGACGGCGCCTCCATCGCCTTCACCTCCTCCGGCCCCGACGCCAAGCCCCGCAAAGATCGCAAGGAAAAATACGGCGAG
TTCGAAATCATCGAGCACGACTACACCATGAGCCATCTCTGGCTCATCAAAGTAGCGGACAACAAGCCCAAAGCCACCGC
GCTCACCAGCGGCGATAAGTTCAGCGTCGGCGCCTTCTCCTGGTCTCCCGACGGCAAACGCATTGCCTTCGCCGCCGGCC
GCGATCCCGACCTCGGTTCGCAGGACACCGAATCCATCTACGTCCTCGATCTGGCCGACCTGCACGTCAAGAAGTTGCTC
GATTCCCCCGGCCCGCACAGCAATCCCAAGTGGTCCCCCAACGGCCGCGAGATCGCCTTCACCACCTCGAACAGCGTGCC
GAATTTCTTCTACGCCAACCGCTACATTGCCGTCATCCCCGCCGATGGCGGACAGCCCCGCCTGCTCACCAAAGATTTCG
ACGAAGACCCGAACCTGCTCGAATGGGCCGATGACGGCATCTATTTCGGCGCCTCCCAGAAGACCGCCGCGCACACCTTC
CGCATTGATCCCGCCACCCGCGCCATCCGCCGCATCACCGGCCCCGATGCCTTTCACGCTACCGGCGGGTCCTTCACCAG
GGACCACCGCACCTTCGCCGGCGTTGGCGCATCACCCAATCGCTTCCCCGAAATCTTTGTCTCCTCCGTCTCCGATTTCG
CTCCCAAATACCTCACCGACGTCGCCGCGCAGTACAAGGATTTCCACCTCGCCACCCGCGAAGTCGTCCAATGGAAATCC
AAGGATGGCGCCTCCATCGAAGGCATCCTGATCAAGCCCGCCGATTTCGATCCCGCACGCAAATACCCGCTGCTCGTCGT
CATCCACGGCGGCCCCACCGGTGTCGATACTCCGCTGATGGCCGCCGACCGCACCTATCCCGTCGAGCGCTTCGTCGCCA
AAGGCGCGCTCGTGCTCAAGCCCAACTACCGCGGCTCCGCCGGCTACGGCGAAAAATTCCGCGCGCTCAACGTCCGCAAC
CTCGGCGTCGGCGATTACGACGACGTCATCACCGGCGTCGATTCCCTGATCGCCAAAGGCATCGTCGATAAAGACAAGGT
CGGCGCTATGGGCTGGAGCCAGGGCGGCTACATCTCGGCGTTCATCACCTGCTACAGCGACCGCTTCAAAGCCGTCAGCG
TCGGCGCCGGAATCTCGGATTGGATGACCTACTACGTCAATACCGACATCCACCCCTTCACCCGCCAGTACCTGAAGGCC
ACTCCGTGGGAAGATCCCGAGATCTATCGCAAGACGTCGCCGATCACCTACGTGAGCCGCGCCCAGACTCCGACGCTGAT
CCAGCACGGCGACCAGGACAAGCGCGTACCGCCTCCCAACGCCTTCGAACTGTACCAGGCCCTCAAAGACCGCAACGTCC
CCGTGAAGCTGATCCTTTACAAAGGTTTCGGCCACCCGATCAACAAGCCCAAACAACAGCGCGCCGTCATGGAACACAAC
TACGATTGGTTCGCCAAATACATCTGGGGCGAAGAGTAA

Upstream 100 bases:

>100_bases
CGTGGCCCACTTTAGACAAACAACTCCTTTGTTTTCAACAAATCAATCAAGAAAAGCGGGCGCTATAGCCCGTTTTTGGG
TTTTCGGCGATAATCTCCCC

Downstream 100 bases:

>100_bases
TCCCGCGAACGGACATGTTTTGTATTACAGTGCTCTTGTTTGCTCGCAGAGCGCAAACATCCGCATCGAAATACTCGCCG
ACATCAGAGCCGCGACCGTC

Product: peptidase S9 prolyl oligopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 652

Protein sequence:

>652_residues
MRYALLLASLLCASAFAAGTVPTIDESLGMKSVAGAQISPDGRYVAYTVQQANWDENDFISQIWIAVTATGERYQLTSGK
KSSTGPQWSPDSHRLAFTSDRDGKRQIYLISPNGGEAIALTSEENGVSAIAWSPDGASIAFTSSGPDAKPRKDRKEKYGE
FEIIEHDYTMSHLWLIKVADNKPKATALTSGDKFSVGAFSWSPDGKRIAFAAGRDPDLGSQDTESIYVLDLADLHVKKLL
DSPGPHSNPKWSPNGREIAFTTSNSVPNFFYANRYIAVIPADGGQPRLLTKDFDEDPNLLEWADDGIYFGASQKTAAHTF
RIDPATRAIRRITGPDAFHATGGSFTRDHRTFAGVGASPNRFPEIFVSSVSDFAPKYLTDVAAQYKDFHLATREVVQWKS
KDGASIEGILIKPADFDPARKYPLLVVIHGGPTGVDTPLMAADRTYPVERFVAKGALVLKPNYRGSAGYGEKFRALNVRN
LGVGDYDDVITGVDSLIAKGIVDKDKVGAMGWSQGGYISAFITCYSDRFKAVSVGAGISDWMTYYVNTDIHPFTRQYLKA
TPWEDPEIYRKTSPITYVSRAQTPTLIQHGDQDKRVPPPNAFELYQALKDRNVPVKLILYKGFGHPINKPKQQRAVMEHN
YDWFAKYIWGEE

Sequences:

>Translated_652_residues
MRYALLLASLLCASAFAAGTVPTIDESLGMKSVAGAQISPDGRYVAYTVQQANWDENDFISQIWIAVTATGERYQLTSGK
KSSTGPQWSPDSHRLAFTSDRDGKRQIYLISPNGGEAIALTSEENGVSAIAWSPDGASIAFTSSGPDAKPRKDRKEKYGE
FEIIEHDYTMSHLWLIKVADNKPKATALTSGDKFSVGAFSWSPDGKRIAFAAGRDPDLGSQDTESIYVLDLADLHVKKLL
DSPGPHSNPKWSPNGREIAFTTSNSVPNFFYANRYIAVIPADGGQPRLLTKDFDEDPNLLEWADDGIYFGASQKTAAHTF
RIDPATRAIRRITGPDAFHATGGSFTRDHRTFAGVGASPNRFPEIFVSSVSDFAPKYLTDVAAQYKDFHLATREVVQWKS
KDGASIEGILIKPADFDPARKYPLLVVIHGGPTGVDTPLMAADRTYPVERFVAKGALVLKPNYRGSAGYGEKFRALNVRN
LGVGDYDDVITGVDSLIAKGIVDKDKVGAMGWSQGGYISAFITCYSDRFKAVSVGAGISDWMTYYVNTDIHPFTRQYLKA
TPWEDPEIYRKTSPITYVSRAQTPTLIQHGDQDKRVPPPNAFELYQALKDRNVPVKLILYKGFGHPINKPKQQRAVMEHN
YDWFAKYIWGEE
>Mature_652_residues
MRYALLLASLLCASAFAAGTVPTIDESLGMKSVAGAQISPDGRYVAYTVQQANWDENDFISQIWIAVTATGERYQLTSGK
KSSTGPQWSPDSHRLAFTSDRDGKRQIYLISPNGGEAIALTSEENGVSAIAWSPDGASIAFTSSGPDAKPRKDRKEKYGE
FEIIEHDYTMSHLWLIKVADNKPKATALTSGDKFSVGAFSWSPDGKRIAFAAGRDPDLGSQDTESIYVLDLADLHVKKLL
DSPGPHSNPKWSPNGREIAFTTSNSVPNFFYANRYIAVIPADGGQPRLLTKDFDEDPNLLEWADDGIYFGASQKTAAHTF
RIDPATRAIRRITGPDAFHATGGSFTRDHRTFAGVGASPNRFPEIFVSSVSDFAPKYLTDVAAQYKDFHLATREVVQWKS
KDGASIEGILIKPADFDPARKYPLLVVIHGGPTGVDTPLMAADRTYPVERFVAKGALVLKPNYRGSAGYGEKFRALNVRN
LGVGDYDDVITGVDSLIAKGIVDKDKVGAMGWSQGGYISAFITCYSDRFKAVSVGAGISDWMTYYVNTDIHPFTRQYLKA
TPWEDPEIYRKTSPITYVSRAQTPTLIQHGDQDKRVPPPNAFELYQALKDRNVPVKLILYKGFGHPINKPKQQRAVMEHN
YDWFAKYIWGEE

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=464, Percent_Identity=25.2155172413793, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI16933540, Length=687, Percent_Identity=21.5429403202329, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI18450280, Length=243, Percent_Identity=26.3374485596708, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI37577089, Length=243, Percent_Identity=26.3374485596708, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI18765694, Length=238, Percent_Identity=28.1512605042017, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI194394146, Length=244, Percent_Identity=23.3606557377049, Blast_Score=69, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17552908, Length=268, Percent_Identity=29.4776119402985, Blast_Score=117, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25149159, Length=367, Percent_Identity=27.2479564032698, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI25144537, Length=248, Percent_Identity=25.4032258064516, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508019, Length=232, Percent_Identity=28.0172413793103, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17508017, Length=232, Percent_Identity=28.0172413793103, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25144540, Length=248, Percent_Identity=25.4032258064516, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324793, Length=252, Percent_Identity=28.968253968254, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24583414, Length=259, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45551969, Length=231, Percent_Identity=25.5411255411255, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550825, Length=231, Percent_Identity=25.5411255411255, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45553511, Length=231, Percent_Identity=25.5411255411255, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 71933; Mature: 71933

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYALLLASLLCASAFAAGTVPTIDESLGMKSVAGAQISPDGRYVAYTVQQANWDENDFI
CHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCEECCCCCEEEEEEEECCCCCHHHH
SQIWIAVTATGERYQLTSGKKSSTGPQWSPDSHRLAFTSDRDGKRQIYLISPNGGEAIAL
EEEEEEEEECCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCEEEE
TSEENGVSAIAWSPDGASIAFTSSGPDAKPRKDRKEKYGEFEIIEHDYTMSHLWLIKVAD
ECCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHHCCCEEEEECCCCEEEEEEEEEEC
NKPKATALTSGDKFSVGAFSWSPDGKRIAFAAGRDPDLGSQDTESIYVLDLADLHVKKLL
CCCCEEEEECCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEEEHHHHHHHHH
DSPGPHSNPKWSPNGREIAFTTSNSVPNFFYANRYIAVIPADGGQPRLLTKDFDEDPNLL
CCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECEEEEEEECCCCCCCEECCCCCCCCCEE
EWADDGIYFGASQKTAAHTFRIDPATRAIRRITGPDAFHATGGSFTRDHRTFAGVGASPN
EECCCCEEECCCCCCCEEEEEECHHHHHHHHCCCCCCEECCCCCCCCCCCEEEECCCCCC
RFPEIFVSSVSDFAPKYLTDVAAQYKDFHLATREVVQWKSKDGASIEGILIKPADFDPAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCC
KYPLLVVIHGGPTGVDTPLMAADRTYPVERFVAKGALVLKPNYRGSAGYGEKFRALNVRN
CCCEEEEECCCCCCCCCCCEECCCCCCHHHHHHCCEEEECCCCCCCCCCCCCEEEEEEEE
LGVGDYDDVITGVDSLIAKGIVDKDKVGAMGWSQGGYISAFITCYSDRFKAVSVGAGISD
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEECCCHHH
WMTYYVNTDIHPFTRQYLKATPWEDPEIYRKTSPITYVSRAQTPTLIQHGDQDKRVPPPN
EEEEEECCCCCHHHHHHHHCCCCCCHHHHCCCCCEEEEECCCCCHHHHCCCCCCCCCCCC
AFELYQALKDRNVPVKLILYKGFGHPINKPKQQRAVMEHNYDWFAKYIWGEE
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEECCCC
>Mature Secondary Structure
MRYALLLASLLCASAFAAGTVPTIDESLGMKSVAGAQISPDGRYVAYTVQQANWDENDFI
CHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCEECCCCCEEEEEEEECCCCCHHHH
SQIWIAVTATGERYQLTSGKKSSTGPQWSPDSHRLAFTSDRDGKRQIYLISPNGGEAIAL
EEEEEEEEECCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCEEEE
TSEENGVSAIAWSPDGASIAFTSSGPDAKPRKDRKEKYGEFEIIEHDYTMSHLWLIKVAD
ECCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHHCCCEEEEECCCCEEEEEEEEEEC
NKPKATALTSGDKFSVGAFSWSPDGKRIAFAAGRDPDLGSQDTESIYVLDLADLHVKKLL
CCCCEEEEECCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEEEHHHHHHHHH
DSPGPHSNPKWSPNGREIAFTTSNSVPNFFYANRYIAVIPADGGQPRLLTKDFDEDPNLL
CCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECEEEEEEECCCCCCCEECCCCCCCCCEE
EWADDGIYFGASQKTAAHTFRIDPATRAIRRITGPDAFHATGGSFTRDHRTFAGVGASPN
EECCCCEEECCCCCCCEEEEEECHHHHHHHHCCCCCCEECCCCCCCCCCCEEEECCCCCC
RFPEIFVSSVSDFAPKYLTDVAAQYKDFHLATREVVQWKSKDGASIEGILIKPADFDPAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCC
KYPLLVVIHGGPTGVDTPLMAADRTYPVERFVAKGALVLKPNYRGSAGYGEKFRALNVRN
CCCEEEEECCCCCCCCCCCEECCCCCCHHHHHHCCEEEECCCCCCCCCCCCCEEEEEEEE
LGVGDYDDVITGVDSLIAKGIVDKDKVGAMGWSQGGYISAFITCYSDRFKAVSVGAGISD
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEECCCHHH
WMTYYVNTDIHPFTRQYLKATPWEDPEIYRKTSPITYVSRAQTPTLIQHGDQDKRVPPPN
EEEEEECCCCCHHHHHHHHCCCCCCHHHHCCCCCEEEEECCCCCHHHHCCCCCCCCCCCC
AFELYQALKDRNVPVKLILYKGFGHPINKPKQQRAVMEHNYDWFAKYIWGEE
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]