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The map label for this gene is yjbC [C]

Identifier: 116625544

GI number: 116625544

Start: 8137227

End: 8137976

Strand: Direct

Name: yjbC [C]

Synonym: Acid_6491

Alternate gene names: 116625544

Gene position: 8137227-8137976 (Clockwise)

Preceding gene: 116625543

Following gene: 116625545

Centisome position: 81.65

GC content: 60.93

Gene sequence:

>750_bases
GTGGCCGAAGAGCGTCTCCAGAAGATCCTCTCTCAAGCCGGTGTATCTTCCCGCCGTCAGGCCGAGAAGCTCATGCAGGA
AGGCCGCGTCACGGTCAACGGCTCCGTCATCACCGAACTGGGAAGCAAGGCCGATCTGGACCGCGATCACATCAAGGTGG
ATGGCCGCCTGCTGAAGGCGCCCAAGCACCAGATCTACATCGCTCTCAACAAACCGAAGGGCACCGTTACCACTGTCCAC
GATCCGGAAGGACGCGAGACCGTCATGGACCTGCTGCACCGCGTAAAGGAACGCGTCTATCCCGTGGGTCGCCTGGACTA
CCATAGCGAAGGACTGCTGCTGTTGACCAACGACGGCGAGCTCGCCAACTCCATCATGTCCGCCGCCACGCACCTGGAGA
AGACTTACGTAGTGAAGGTGACTGGCACCCTCACCGCCGAGCAGGAAGAGAAGTTCCGCACCGGCGTTCCGCTCAGCGGC
CGGCGCACCCTGCCGGCCGGCCTGAAACTGCTCAGCCGCGCCGAGAACCCCTGGTACGAGGTCAAGCTCACCGAAGGCCG
CAACAACCAGATCCGCATGATGTTCAGGCATTTCGGAAAGCTGGTGGAGAAATTAAAGCGCGTGCGCATTGGCCCGATCG
AACTCGGCACCTTGAAAACCGGCGCATTCCGCTATCTCGACGAAGAAGACGTCGCCAAGCTCAAGCGCGCCATTCAGCGC
TCCAGCCAGAAGCCGGCGAAAAAGGTATGA

Upstream 100 bases:

>100_bases
CGAGCCCGCCACCGAACCGACCGAACCGGGTGAGCCGGGTGAGACGGCAGAACCGGCCGAACCACCCTCGGAGCCCGTAC
CGCAAAGTGAGGAAAACTAA

Downstream 100 bases:

>100_bases
ACCAGCTTACCGAGGTCCTGCGGCAGTCCCACACTATCGCGGTGGTCGGCCTCTCCGGCAAACGCTTCCGCCCCAGCTAT
GGAGTCGCGGAGTATATGCA

Product: ribosomal large subunit pseudouridine synthase B

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MAEERLQKILSQAGVSSRRQAEKLMQEGRVTVNGSVITELGSKADLDRDHIKVDGRLLKAPKHQIYIALNKPKGTVTTVH
DPEGRETVMDLLHRVKERVYPVGRLDYHSEGLLLLTNDGELANSIMSAATHLEKTYVVKVTGTLTAEQEEKFRTGVPLSG
RRTLPAGLKLLSRAENPWYEVKLTEGRNNQIRMMFRHFGKLVEKLKRVRIGPIELGTLKTGAFRYLDEEDVAKLKRAIQR
SSQKPAKKV

Sequences:

>Translated_249_residues
MAEERLQKILSQAGVSSRRQAEKLMQEGRVTVNGSVITELGSKADLDRDHIKVDGRLLKAPKHQIYIALNKPKGTVTTVH
DPEGRETVMDLLHRVKERVYPVGRLDYHSEGLLLLTNDGELANSIMSAATHLEKTYVVKVTGTLTAEQEEKFRTGVPLSG
RRTLPAGLKLLSRAENPWYEVKLTEGRNNQIRMMFRHFGKLVEKLKRVRIGPIELGTLKTGAFRYLDEEDVAKLKRAIQR
SSQKPAKKV
>Mature_248_residues
AEERLQKILSQAGVSSRRQAEKLMQEGRVTVNGSVITELGSKADLDRDHIKVDGRLLKAPKHQIYIALNKPKGTVTTVHD
PEGRETVMDLLHRVKERVYPVGRLDYHSEGLLLLTNDGELANSIMSAATHLEKTYVVKVTGTLTAEQEEKFRTGVPLSGR
RTLPAGLKLLSRAENPWYEVKLTEGRNNQIRMMFRHFGKLVEKLKRVRIGPIELGTLKTGAFRYLDEEDVAKLKRAIQRS
SQKPAKKV

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790453, Length=243, Percent_Identity=37.4485596707819, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787524, Length=235, Percent_Identity=39.1489361702128, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1788510, Length=233, Percent_Identity=33.0472103004292, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87081838, Length=174, Percent_Identity=35.0574712643678, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 28086; Mature: 27955

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEERLQKILSQAGVSSRRQAEKLMQEGRVTVNGSVITELGSKADLDRDHIKVDGRLLKA
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECCHHHHHCCCCCCCCCCCEEECCEEEEC
PKHQIYIALNKPKGTVTTVHDPEGRETVMDLLHRVKERVYPVGRLDYHSEGLLLLTNDGE
CCEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCH
LANSIMSAATHLEKTYVVKVTGTLTAEQEEKFRTGVPLSGRRTLPAGLKLLSRAENPWYE
HHHHHHHHHHHHCCEEEEEEEEEEECCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEE
VKLTEGRNNQIRMMFRHFGKLVEKLKRVRIGPIELGTLKTGAFRYLDEEDVAKLKRAIQR
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHCCCHHHHHHHHHHHHH
SSQKPAKKV
HCCCCCCCC
>Mature Secondary Structure 
AEERLQKILSQAGVSSRRQAEKLMQEGRVTVNGSVITELGSKADLDRDHIKVDGRLLKA
CHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECCHHHHHCCCCCCCCCCCEEECCEEEEC
PKHQIYIALNKPKGTVTTVHDPEGRETVMDLLHRVKERVYPVGRLDYHSEGLLLLTNDGE
CCEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCH
LANSIMSAATHLEKTYVVKVTGTLTAEQEEKFRTGVPLSGRRTLPAGLKLLSRAENPWYE
HHHHHHHHHHHHCCEEEEEEEEEEECCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEE
VKLTEGRNNQIRMMFRHFGKLVEKLKRVRIGPIELGTLKTGAFRYLDEEDVAKLKRAIQR
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHCCCHHHHHHHHHHHHH
SSQKPAKKV
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]