Click here to switch to the map view.

The map label for this gene is emrA [C]

Identifier: 116625540

GI number: 116625540

Start: 8131298

End: 8132710

Strand: Reverse

Name: emrA [C]

Synonym: Acid_6487

Alternate gene names: 116625540

Gene position: 8132710-8131298 (Counterclockwise)

Preceding gene: 116625541

Following gene: 116625539

Centisome position: 81.61

GC content: 61.0

Gene sequence:

>1413_bases
ATGCAACCGACACCGAGTAAAGCGCCGGTTCCGGCGCCGCCGCAACCGGGACCAACGGTGGTCCCGCCGAAAACAGAACC
AGAGCGTAAGCGGACCGGCATGTGGATCGCGCTGGTGCTCGTTCTGGTGGTCGGCGCAGGAGCCGCGTACTACTTCAAAA
CCCAGAACGATGCGAAAGTCGCGAACAAAGGATCGGTGATTTCGGTCTCCACGATGGTAGTGGGCCTGGGAGACATCCAC
TCCACCGTACGAGTGAACGGCACGGTCAACGCCCAAAACTTCGCCGCCCTGATGGCGCCGCGTATTCTCGGCAGCCGCAG
CGGACTGAACCGCGGTGGCGATGGCGGTGGAGGCGGCGGTAATCCGGGTGGTGGCGGCGGTGGCGGCGGTCCGATGGGCG
ACTTCAGCCTGGTGCTGATGAAGCTCGCCAACCCGGGCGTTCGCGTCAAGACCGGCGACGTTGTTGCCGAATTCGATCCT
CAGAACCAGTTGCAGCGCCTCGACGATTATAAGGACACGGCGATTCAGCAGGAGAACATGGTCAAGAAGATGATGGCCAA
CCTGGCTGCCGTGAAGGAAGCCCACAACCAGCAGGTCCGTTCCGCAAAGGCCGATTGGGACAAGGCGGTACTCGACCTGA
AGACCGCTGAAGTTCGCTCCGCCATCGACGCCGAGAAATATAAACTCACGGTGGAAGAGGACGAGGCCAATTACAAACAG
TTGTTGGCCGAAGCCGCCCTGGTGGAAGAATCGCAGCGCGCTCAGATCCGCTCCTCGGAGCTGAACCGCGATCAGTCCAA
GATCGAAATGGCGCGCGCCGAAGCCAACGTCAAGAAGATGTCGGTGAAGGCGCCGATGGATGGTATCGTCGTGATGCAGA
GCATCGTCCGCAACGGCGAATTCGGCCAGATCCGCGAGGGCGATCAGGTCGCCGCCGGCCAGCCGTTCGTGCAGATCGTG
GACCCAAGTTCGATGGTTCTCAACGCGACCGTCAACCAGGTGGATGCTGAGAAGCTGCGCTTGGGCATGAAAGCGACCAT
TCACATGGATGCCTATCCGGATATCGAACTGCCCGGGACCCTGGTCGGAATCGGGGCGATGGCGAAGGCCAGCACCTTCC
GGGCACGGTTCGTCGGCGAGATCCCGGTCCGTATCAAGTTGGAAAAGACGGACCCGCGTGTAATTCCCGATTTGACGGGC
AGCGCGGAGATCGTGCTCGGCAGTGAACGGAATACGATGGTGGCGCCTCTCTCGGCGGTCTTTGCCGAAGACGGCGGATC
CTATGTGTTCGTGCAGGGGTCCGAGGGCTGGATCAAGAAGAAGGTAGAACTCGGACTACCCAATTTCACGACCGTGGCGA
TCAAGTCCGGCGTGCAGAAAGGGGACGTCATCGCGCTGCAACGTCCCATGTAG

Upstream 100 bases:

>100_bases
TTTAGAGCTATCCCGGAATAACCTTTGAGGGCTAGGCGACGTCTTCACGTTGAACTAAAAAACACTGACCGCAAGGGCCC
AAGGTCTTTGGAAGGATTTA

Downstream 100 bases:

>100_bases
GGCGCGCGCTACCGACAGGAATAACCCATGCCATCCAAGGACCAACGGCCCAGCCAGCGACTGGGAAAATCGAACCCGCG
AAGGGTCAAGATCATCACCT

Product: multidrug resistance efflux pump-like protein

Products: NA

Alternate protein names: Membrane-Fusion Protein; RND Family Efflux Transporter MFP Subunit; Multidrug Resistance Efflux Pump-Like Protein; Secretion Protein HlyD; HlyD Family Secretion Protein; Efflux Transporter Rnd Family Mfp Subunit; PAS/PAC Sensor Protein; Secretion Protein HlyD Family Protein; Membrane Fusion Protein; Membrane-Fusion Protein-Like Protein

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MQPTPSKAPVPAPPQPGPTVVPPKTEPERKRTGMWIALVLVLVVGAGAAYYFKTQNDAKVANKGSVISVSTMVVGLGDIH
STVRVNGTVNAQNFAALMAPRILGSRSGLNRGGDGGGGGGNPGGGGGGGGPMGDFSLVLMKLANPGVRVKTGDVVAEFDP
QNQLQRLDDYKDTAIQQENMVKKMMANLAAVKEAHNQQVRSAKADWDKAVLDLKTAEVRSAIDAEKYKLTVEEDEANYKQ
LLAEAALVEESQRAQIRSSELNRDQSKIEMARAEANVKKMSVKAPMDGIVVMQSIVRNGEFGQIREGDQVAAGQPFVQIV
DPSSMVLNATVNQVDAEKLRLGMKATIHMDAYPDIELPGTLVGIGAMAKASTFRARFVGEIPVRIKLEKTDPRVIPDLTG
SAEIVLGSERNTMVAPLSAVFAEDGGSYVFVQGSEGWIKKKVELGLPNFTTVAIKSGVQKGDVIALQRPM

Sequences:

>Translated_470_residues
MQPTPSKAPVPAPPQPGPTVVPPKTEPERKRTGMWIALVLVLVVGAGAAYYFKTQNDAKVANKGSVISVSTMVVGLGDIH
STVRVNGTVNAQNFAALMAPRILGSRSGLNRGGDGGGGGGNPGGGGGGGGPMGDFSLVLMKLANPGVRVKTGDVVAEFDP
QNQLQRLDDYKDTAIQQENMVKKMMANLAAVKEAHNQQVRSAKADWDKAVLDLKTAEVRSAIDAEKYKLTVEEDEANYKQ
LLAEAALVEESQRAQIRSSELNRDQSKIEMARAEANVKKMSVKAPMDGIVVMQSIVRNGEFGQIREGDQVAAGQPFVQIV
DPSSMVLNATVNQVDAEKLRLGMKATIHMDAYPDIELPGTLVGIGAMAKASTFRARFVGEIPVRIKLEKTDPRVIPDLTG
SAEIVLGSERNTMVAPLSAVFAEDGGSYVFVQGSEGWIKKKVELGLPNFTTVAIKSGVQKGDVIALQRPM
>Mature_470_residues
MQPTPSKAPVPAPPQPGPTVVPPKTEPERKRTGMWIALVLVLVVGAGAAYYFKTQNDAKVANKGSVISVSTMVVGLGDIH
STVRVNGTVNAQNFAALMAPRILGSRSGLNRGGDGGGGGGNPGGGGGGGGPMGDFSLVLMKLANPGVRVKTGDVVAEFDP
QNQLQRLDDYKDTAIQQENMVKKMMANLAAVKEAHNQQVRSAKADWDKAVLDLKTAEVRSAIDAEKYKLTVEEDEANYKQ
LLAEAALVEESQRAQIRSSELNRDQSKIEMARAEANVKKMSVKAPMDGIVVMQSIVRNGEFGQIREGDQVAAGQPFVQIV
DPSSMVLNATVNQVDAEKLRLGMKATIHMDAYPDIELPGTLVGIGAMAKASTFRARFVGEIPVRIKLEKTDPRVIPDLTG
SAEIVLGSERNTMVAPLSAVFAEDGGSYVFVQGSEGWIKKKVELGLPNFTTVAIKSGVQKGDVIALQRPM

Specific function: The Emr Locus Confers Resistance To Substances Of High Hydrophobicity. Emra Probably Participate In A Transport System To Extrude Toxins And Drugs From The Cell. [C]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50038; Mature: 50038

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPTPSKAPVPAPPQPGPTVVPPKTEPERKRTGMWIALVLVLVVGAGAAYYFKTQNDAKV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCC
ANKGSVISVSTMVVGLGDIHSTVRVNGTVNAQNFAALMAPRILGSRSGLNRGGDGGGGGG
CCCCCEEEEEEEEEECCCCCCEEEEECEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NPGGGGGGGGPMGDFSLVLMKLANPGVRVKTGDVVAEFDPQNQLQRLDDYKDTAIQQENM
CCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHH
VKKMMANLAAVKEAHNQQVRSAKADWDKAVLDLKTAEVRSAIDAEKYKLTVEEDEANYKQ
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
LLAEAALVEESQRAQIRSSELNRDQSKIEMARAEANVKKMSVKAPMDGIVVMQSIVRNGE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHEEEECCCCCHHHHHHHHHCCCC
FGQIREGDQVAAGQPFVQIVDPSSMVLNATVNQVDAEKLRLGMKATIHMDAYPDIELPGT
CCCCCCCCCCCCCCCEEEEECCCCEEEECHHHHCCHHHHHCCCEEEEEECCCCCCCCCCC
LVGIGAMAKASTFRARFVGEIPVRIKLEKTDPRVIPDLTGSAEIVLGSERNTMVAPLSAV
EEECCHHHHHHHHHHHEEECCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCEEHHHHHH
FAEDGGSYVFVQGSEGWIKKKVELGLPNFTTVAIKSGVQKGDVIALQRPM
HHCCCCCEEEEECCCCCEEEEEECCCCCCEEEEECCCCCCCCEEEEECCC
>Mature Secondary Structure
MQPTPSKAPVPAPPQPGPTVVPPKTEPERKRTGMWIALVLVLVVGAGAAYYFKTQNDAKV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCC
ANKGSVISVSTMVVGLGDIHSTVRVNGTVNAQNFAALMAPRILGSRSGLNRGGDGGGGGG
CCCCCEEEEEEEEEECCCCCCEEEEECEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NPGGGGGGGGPMGDFSLVLMKLANPGVRVKTGDVVAEFDPQNQLQRLDDYKDTAIQQENM
CCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHH
VKKMMANLAAVKEAHNQQVRSAKADWDKAVLDLKTAEVRSAIDAEKYKLTVEEDEANYKQ
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
LLAEAALVEESQRAQIRSSELNRDQSKIEMARAEANVKKMSVKAPMDGIVVMQSIVRNGE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHEEEECCCCCHHHHHHHHHCCCC
FGQIREGDQVAAGQPFVQIVDPSSMVLNATVNQVDAEKLRLGMKATIHMDAYPDIELPGT
CCCCCCCCCCCCCCCEEEEECCCCEEEECHHHHCCHHHHHCCCEEEEEECCCCCCCCCCC
LVGIGAMAKASTFRARFVGEIPVRIKLEKTDPRVIPDLTGSAEIVLGSERNTMVAPLSAV
EEECCHHHHHHHHHHHEEECCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCEEHHHHHH
FAEDGGSYVFVQGSEGWIKKKVELGLPNFTTVAIKSGVQKGDVIALQRPM
HHCCCCCEEEEECCCCCEEEEEECCCCCCEEEEECCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA