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The map label for this gene is xerD [H]

Identifier: 116625461

GI number: 116625461

Start: 8023422

End: 8024330

Strand: Direct

Name: xerD [H]

Synonym: Acid_6406

Alternate gene names: 116625461

Gene position: 8023422-8024330 (Clockwise)

Preceding gene: 116625456

Following gene: 116625462

Centisome position: 80.51

GC content: 61.72

Gene sequence:

>909_bases
ATGTCTGGAGCGCTCGCGGAAGGTTCGGCGGTTCTGTGCGGCCAGACTGCTGCGTTCCTCAATTTCTGCCGTATCGAGAA
GGGGCTTTCGCCCAATTCGATCTCGGCGTACTCCGCAGATCTCGCTCGTTTTGTTCAATTTACAGGGGATGTCCAGGAGC
CTCCGGGGGTTCCGGAAATCCGCCAATATATCGATCATCTGTACCAAACGGGACTCAGCAACCGGTCGGTAGGCCGGCAT
TTGACCACTTTGCGAAACTTCTACGGGTTCCTGCTCAGGGAGGGTAAGGTCGCCACCGACCCTACCGAGCACCTGCGCAC
CCCCCGGCAGTGGCAGACTATTCCTAAGTATCTGAATCTGGAGGAGATCGAGCGCATTATTCAAGCGCCGGACCTGGCCA
AACCGCTCGGTCTGCGGGACCGGGCCATGATGGAAGTGCTGTACGCTTCCGGTTTGCGGGTGAGTGAACTGTGCAAACTG
GGCATCGGCGACCTGGACCTGGAATACCAGGTTTTGCGGACCACCGGGAAGGGCAACAAGCAGCGCCTGGTGCCGGTCGG
GAAGGCGGCGGTCCTGGCGGTGCGGGCGTACCTGGAATCCGGACGCCCTGGGCTCTTGAAGGGGCGGGCGAGCCGGTACC
TGTTCGTCACCGCGCGCGGCGGATGTATGACGCGGCAGGGTTTTTGGAAACTGTTGGCGGCGTATGGCAGGAAGGCCGGC
ATTTTCCATGGCTTGACGCCGCACGTGCTGCGTCACAGTTTCGCCACCCACCTTTTGGAGGGCGGAGCCGACCTGCGCAG
CGTGCAGGTCATGCTGGGCCATGCCGATATCTCGACCACCCAGATCTACACCCACGTGATGCGCTCGCGACTTCGGGCGA
CCGTGGAGAAGCATCACCCCCGGGCGTGA

Upstream 100 bases:

>100_bases
AGCGGCGAATCAGCGCCTTTTTGGTGGTGGAGGAGGCCAAGATTCCTCAGTGCAACAACAATGTTTCAAACATTTTGCGA
CTTATTGTATCATTGGCACG

Downstream 100 bases:

>100_bases
TCCGGTTTTGAAGAGCTGGATGCCGGGCAGTTTAGTTCTGTTGGAAAGCGCAATTCGATGAGCGATTACATCTACATGCT
GGAGAGCCACCTGAGCCCGG

Product: tyrosine recombinase XerD subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSGALAEGSAVLCGQTAAFLNFCRIEKGLSPNSISAYSADLARFVQFTGDVQEPPGVPEIRQYIDHLYQTGLSNRSVGRH
LTTLRNFYGFLLREGKVATDPTEHLRTPRQWQTIPKYLNLEEIERIIQAPDLAKPLGLRDRAMMEVLYASGLRVSELCKL
GIGDLDLEYQVLRTTGKGNKQRLVPVGKAAVLAVRAYLESGRPGLLKGRASRYLFVTARGGCMTRQGFWKLLAAYGRKAG
IFHGLTPHVLRHSFATHLLEGGADLRSVQVMLGHADISTTQIYTHVMRSRLRATVEKHHPRA

Sequences:

>Translated_302_residues
MSGALAEGSAVLCGQTAAFLNFCRIEKGLSPNSISAYSADLARFVQFTGDVQEPPGVPEIRQYIDHLYQTGLSNRSVGRH
LTTLRNFYGFLLREGKVATDPTEHLRTPRQWQTIPKYLNLEEIERIIQAPDLAKPLGLRDRAMMEVLYASGLRVSELCKL
GIGDLDLEYQVLRTTGKGNKQRLVPVGKAAVLAVRAYLESGRPGLLKGRASRYLFVTARGGCMTRQGFWKLLAAYGRKAG
IFHGLTPHVLRHSFATHLLEGGADLRSVQVMLGHADISTTQIYTHVMRSRLRATVEKHHPRA
>Mature_301_residues
SGALAEGSAVLCGQTAAFLNFCRIEKGLSPNSISAYSADLARFVQFTGDVQEPPGVPEIRQYIDHLYQTGLSNRSVGRHL
TTLRNFYGFLLREGKVATDPTEHLRTPRQWQTIPKYLNLEEIERIIQAPDLAKPLGLRDRAMMEVLYASGLRVSELCKLG
IGDLDLEYQVLRTTGKGNKQRLVPVGKAAVLAVRAYLESGRPGLLKGRASRYLFVTARGGCMTRQGFWKLLAAYGRKAGI
FHGLTPHVLRHSFATHLLEGGADLRSVQVMLGHADISTTQIYTHVMRSRLRATVEKHHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=288, Percent_Identity=46.1805555555556, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1790244, Length=288, Percent_Identity=34.7222222222222, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1790767, Length=170, Percent_Identity=30, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790768, Length=191, Percent_Identity=29.3193717277487, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33520; Mature: 33389

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGALAEGSAVLCGQTAAFLNFCRIEKGLSPNSISAYSADLARFVQFTGDVQEPPGVPEI
CCCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHH
RQYIDHLYQTGLSNRSVGRHLTTLRNFYGFLLREGKVATDPTEHLRTPRQWQTIPKYLNL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHCCH
EEIERIIQAPDLAKPLGLRDRAMMEVLYASGLRVSELCKLGIGDLDLEYQVLRTTGKGNK
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHEEEECCCCCC
QRLVPVGKAAVLAVRAYLESGRPGLLKGRASRYLFVTARGGCMTRQGFWKLLAAYGRKAG
CEEEECHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
IFHGLTPHVLRHSFATHLLEGGADLRSVQVMLGHADISTTQIYTHVMRSRLRATVEKHHP
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
RA
CC
>Mature Secondary Structure 
SGALAEGSAVLCGQTAAFLNFCRIEKGLSPNSISAYSADLARFVQFTGDVQEPPGVPEI
CCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHH
RQYIDHLYQTGLSNRSVGRHLTTLRNFYGFLLREGKVATDPTEHLRTPRQWQTIPKYLNL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHCCH
EEIERIIQAPDLAKPLGLRDRAMMEVLYASGLRVSELCKLGIGDLDLEYQVLRTTGKGNK
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHEEEECCCCCC
QRLVPVGKAAVLAVRAYLESGRPGLLKGRASRYLFVTARGGCMTRQGFWKLLAAYGRKAG
CEEEECHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
IFHGLTPHVLRHSFATHLLEGGADLRSVQVMLGHADISTTQIYTHVMRSRLRATVEKHHP
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
RA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]