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The map label for this gene is ampC [C]

Identifier: 116625407

GI number: 116625407

Start: 7969813

End: 7971672

Strand: Reverse

Name: ampC [C]

Synonym: Acid_6352

Alternate gene names: 116625407

Gene position: 7971672-7969813 (Counterclockwise)

Preceding gene: 116625408

Following gene: 116625401

Centisome position: 79.99

GC content: 63.92

Gene sequence:

>1860_bases
ATGGCGAATCGTTTTGCGATCCCCGAAGGATGGCGCTTGGAGAGCAGCGGAGAGGTCTCCACGCTGGTTGGGCCGGAAGG
CGACCTGCGCCTGGACTTCGTGGATCTCGCTCCCGGCGGAAGTGTTCAGCAGACCGCGCTGGCGGCGTGGAAGTTGGTGG
ACCCGGACTTCGCCTCCACGGTGACCAGGGAGGTGGCGGCGCCGCCCCAGGATGGCTGGGATGAGATGCACCAGGTGCTC
TACGCCACGCCGGCCCAGGAAGCCCGCGCCGAACTCGCGATCGTGCGAAAGCTGGGTGGGCGGGCTTTCGTCAATCTGAT
CCGCGCATCCACGGCGGGGCTGAGCCGGCGGAACGCGCAACTCACCGAAGCGATCGGGAGTTGGAAGCCGGAGGGATTCC
GGGAGGTCAGCCTCAAGGACGTAGCGCCGGTAGTGTGGAGCGAAGAGAAGAGCGCGCGCCTGAAAGAGTTCGCGATTTCG
GCGATGCAGACGTTGCAGGTTCCCGGCGCCGCCATGGCGATTGTGCAGGGCGGCCGCGTCGTGTATGCAGAGGGCCTGGG
AGTCCGCGATCTTGGCCGCGGAGAGCCGGTCACTCCGCGGACGCGCTTCATGATCGGCTCCTCGACGAAAGCCCTGACTA
GTCTTATGATGGCGAAGCTGGTGGAGCAGGGGAAGCTGAGCTGGTCCACGCCTGTGGTGGACCTGCTCCCGGATTTCGCG
CTGGCGGATGCGAACGTCACGCGCCGGCTGGAAATTCGGCACACGGTGTCGGCGTCCACCGGAATGCCGCGGCAGGATCT
GGAATTCGTCTTCAAGTACTCCGGCGTTACCCCGGAAGACCGCATCGCGCAGATGAAGACCATGCGGCCGACTACGGGTT
TCGGAGAGACCTTTCAATATTCGAATTTTCTCGTGGCCGCGGGCGGGTATGCGGCGGGGCGGGCCCATTCGGCGTATGGC
GGCCTCGAAAAGGCCTTTGAGAGCGCGATCGGGGAGTTGGTCTTCCGCCCGCTGGCGATGAACAACAGTTGCCTGCGGCA
GGAGGACGCAATGAAAGGCGAGGCGGCGTTACCCCACGCGACCAACTTCGAGGGAGGCGTCAGCCGCATTCCGTTGAGCA
TCGAGATGTCCGTGCAGAGCGTCGCCCCCGCCGGTGCGGCGTGGTCCACCGCGCTGGACCTGGCCCGGTACCTGATGCTG
GAGCTCGGCAAAGGGCGCACGCCCGGTGGGGAACGGGTAGTCGGGGAAGAGTTCCTCCTGGAGCGCAGGATCAAAGGGAT
CAAGATCGATCAGAACAACTCGTACGGTCTGGGACTGATCGTGAGCGATGATTCCGGCCTGCAGGTAATTCATCACGGCG
GCAACACCTTCGGCTTCTCAAGCGACATGTACTTCCTTCCGGAGCGCGACTTGGGCCTCGTGGTGCTCACCAACGTCTAT
CAGGCGAGCATGTTCCTGGCGGCAATGCGGCAGCGGGTCTTCGAACTCACGTTTGGGGCGGAGCCGAAAGCCGAAAAGAC
AGTTGCGGCGGCCGTGAAGATGCGGCAGGACGGCGTCGCGGACCTTCGCGCAAGAGTGAACTCGGATGCCGCATCCATGG
CCTGGGTGGACGAACTCGCCGGGCAGTTCGAGTGCGCGGAGCTCGGTCCCTGCGAAATCTCCAGGCGCGGGGAGGGCTAC
GGGATAGAATTTTCGGAATGGGGCGGCGAATTGGGTTGCGAGATCGAACCCGGCGGCGGCCGCCTCCTGAGAATCTTGAG
TCCGCCGTGGCGCGGCGGACTCAAGTTCGTGGTCAACACCGATCTTCGAACACTCACTCTTGACGGCGGGCAGAGTAAGT
ACGTTTTTCAAAAACGGTGA

Upstream 100 bases:

>100_bases
TGACCGCGCCTGAAGAACCGGGTATGAGCAGCGAAGTCCCTGACGCCGACATTCGACGCTTCAAGGTGTGACCGGCTTAC
ACAAGAAATCGCGAGGAACC

Downstream 100 bases:

>100_bases
GCGCACCTACTCGACGTTGCTCAGCTGATAGCCGGTGTGATCGCTGAACAACACCTTCGAGAGTTGGAGATCATCACCGT
GGCGGCTGAGGACGATGCTG

Product: beta-lactamase

Products: A Substituted Beta- Amino Acid. [C]

Alternate protein names: Beta-Lactamase Class C; Beta-Lactamase Family Protein; Beta-Lactamase-Like Protein; Beta-Lactamase Class C-Like Protein; Beta-Lactamase Protein; Cyclic Peptide Transporter; Protein Flp; Serine-Type D-Ala-D-Ala Carboxypeptidase; FmtA-Like Protein; Non-Ribosomal Peptide Synthetase; Class-C Beta-Lactamase Family Protein; Exported Beta-Lactamase; N-Acetylmuramyl-L-Alanine Amidase; Beta-Lactamase/Prolyl Oligopeptidase; 6Fe-6S Prismane Cluster-Containing Protein-Like Protein; Beta-Lactamase Class C Family Protein; D-Aminoacylase; Beta-Lactamase Family; S9 Family Peptidase; Beta-LactamaseCopper Amine Oxidase-Like Protein; Secreted Protein

Number of amino acids: Translated: 619; Mature: 618

Protein sequence:

>619_residues
MANRFAIPEGWRLESSGEVSTLVGPEGDLRLDFVDLAPGGSVQQTALAAWKLVDPDFASTVTREVAAPPQDGWDEMHQVL
YATPAQEARAELAIVRKLGGRAFVNLIRASTAGLSRRNAQLTEAIGSWKPEGFREVSLKDVAPVVWSEEKSARLKEFAIS
AMQTLQVPGAAMAIVQGGRVVYAEGLGVRDLGRGEPVTPRTRFMIGSSTKALTSLMMAKLVEQGKLSWSTPVVDLLPDFA
LADANVTRRLEIRHTVSASTGMPRQDLEFVFKYSGVTPEDRIAQMKTMRPTTGFGETFQYSNFLVAAGGYAAGRAHSAYG
GLEKAFESAIGELVFRPLAMNNSCLRQEDAMKGEAALPHATNFEGGVSRIPLSIEMSVQSVAPAGAAWSTALDLARYLML
ELGKGRTPGGERVVGEEFLLERRIKGIKIDQNNSYGLGLIVSDDSGLQVIHHGGNTFGFSSDMYFLPERDLGLVVLTNVY
QASMFLAAMRQRVFELTFGAEPKAEKTVAAAVKMRQDGVADLRARVNSDAASMAWVDELAGQFECAELGPCEISRRGEGY
GIEFSEWGGELGCEIEPGGGRLLRILSPPWRGGLKFVVNTDLRTLTLDGGQSKYVFQKR

Sequences:

>Translated_619_residues
MANRFAIPEGWRLESSGEVSTLVGPEGDLRLDFVDLAPGGSVQQTALAAWKLVDPDFASTVTREVAAPPQDGWDEMHQVL
YATPAQEARAELAIVRKLGGRAFVNLIRASTAGLSRRNAQLTEAIGSWKPEGFREVSLKDVAPVVWSEEKSARLKEFAIS
AMQTLQVPGAAMAIVQGGRVVYAEGLGVRDLGRGEPVTPRTRFMIGSSTKALTSLMMAKLVEQGKLSWSTPVVDLLPDFA
LADANVTRRLEIRHTVSASTGMPRQDLEFVFKYSGVTPEDRIAQMKTMRPTTGFGETFQYSNFLVAAGGYAAGRAHSAYG
GLEKAFESAIGELVFRPLAMNNSCLRQEDAMKGEAALPHATNFEGGVSRIPLSIEMSVQSVAPAGAAWSTALDLARYLML
ELGKGRTPGGERVVGEEFLLERRIKGIKIDQNNSYGLGLIVSDDSGLQVIHHGGNTFGFSSDMYFLPERDLGLVVLTNVY
QASMFLAAMRQRVFELTFGAEPKAEKTVAAAVKMRQDGVADLRARVNSDAASMAWVDELAGQFECAELGPCEISRRGEGY
GIEFSEWGGELGCEIEPGGGRLLRILSPPWRGGLKFVVNTDLRTLTLDGGQSKYVFQKR
>Mature_618_residues
ANRFAIPEGWRLESSGEVSTLVGPEGDLRLDFVDLAPGGSVQQTALAAWKLVDPDFASTVTREVAAPPQDGWDEMHQVLY
ATPAQEARAELAIVRKLGGRAFVNLIRASTAGLSRRNAQLTEAIGSWKPEGFREVSLKDVAPVVWSEEKSARLKEFAISA
MQTLQVPGAAMAIVQGGRVVYAEGLGVRDLGRGEPVTPRTRFMIGSSTKALTSLMMAKLVEQGKLSWSTPVVDLLPDFAL
ADANVTRRLEIRHTVSASTGMPRQDLEFVFKYSGVTPEDRIAQMKTMRPTTGFGETFQYSNFLVAAGGYAAGRAHSAYGG
LEKAFESAIGELVFRPLAMNNSCLRQEDAMKGEAALPHATNFEGGVSRIPLSIEMSVQSVAPAGAAWSTALDLARYLMLE
LGKGRTPGGERVVGEEFLLERRIKGIKIDQNNSYGLGLIVSDDSGLQVIHHGGNTFGFSSDMYFLPERDLGLVVLTNVYQ
ASMFLAAMRQRVFELTFGAEPKAEKTVAAAVKMRQDGVADLRARVNSDAASMAWVDELAGQFECAELGPCEISRRGEGYG
IEFSEWGGELGCEIEPGGGRLLRILSPPWRGGLKFVVNTDLRTLTLDGGQSKYVFQKR

Specific function: This Protein Is A Serine Beta-Lactamase With A Substrate Specificity For Cephalosporins. [C]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.5.2.6 [C]

Molecular weight: Translated: 67112; Mature: 66981

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANRFAIPEGWRLESSGEVSTLVGPEGDLRLDFVDLAPGGSVQQTALAAWKLVDPDFAST
CCCCCCCCCCCEECCCCCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHEECCCHHHHH
VTREVAAPPQDGWDEMHQVLYATPAQEARAELAIVRKLGGRAFVNLIRASTAGLSRRNAQ
HHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHH
LTEAIGSWKPEGFREVSLKDVAPVVWSEEKSARLKEFAISAMQTLQVPGAAMAIVQGGRV
HHHHHHCCCCCCCEEECHHHCCCCEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCEE
VYAEGLGVRDLGRGEPVTPRTRFMIGSSTKALTSLMMAKLVEQGKLSWSTPVVDLLPDFA
EEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHH
LADANVTRRLEIRHTVSASTGMPRQDLEFVFKYSGVTPEDRIAQMKTMRPTTGFGETFQY
CCCCCCEEEEEEEEEECCCCCCCHHHHHHHHEECCCCCHHHHHHHHHCCCCCCCCCCEEC
SNFLVAAGGYAAGRAHSAYGGLEKAFESAIGELVFRPLAMNNSCLRQEDAMKGEAALPHA
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCC
TNFEGGVSRIPLSIEMSVQSVAPAGAAWSTALDLARYLMLELGKGRTPGGERVVGEEFLL
CCCCCCCEECCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
ERRIKGIKIDQNNSYGLGLIVSDDSGLQVIHHGGNTFGFSSDMYFLPERDLGLVVLTNVY
HHHCCCEEEECCCCCEEEEEEECCCCEEEEEECCCCCCCCCCEEECCCCCCCEEEEHHHH
QASMFLAAMRQRVFELTFGAEPKAEKTVAAAVKMRQDGVADLRARVNSDAASMAWVDELA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHC
GQFECAELGPCEISRRGEGYGIEFSEWGGELGCEIEPGGGRLLRILSPPWRGGLKFVVNT
CCEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCEEECCCCEEEEEECCCCCCCEEEEEEC
DLRTLTLDGGQSKYVFQKR
CEEEEEECCCCCCEEEECC
>Mature Secondary Structure 
ANRFAIPEGWRLESSGEVSTLVGPEGDLRLDFVDLAPGGSVQQTALAAWKLVDPDFAST
CCCCCCCCCCEECCCCCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHEECCCHHHHH
VTREVAAPPQDGWDEMHQVLYATPAQEARAELAIVRKLGGRAFVNLIRASTAGLSRRNAQ
HHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHH
LTEAIGSWKPEGFREVSLKDVAPVVWSEEKSARLKEFAISAMQTLQVPGAAMAIVQGGRV
HHHHHHCCCCCCCEEECHHHCCCCEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCEE
VYAEGLGVRDLGRGEPVTPRTRFMIGSSTKALTSLMMAKLVEQGKLSWSTPVVDLLPDFA
EEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHH
LADANVTRRLEIRHTVSASTGMPRQDLEFVFKYSGVTPEDRIAQMKTMRPTTGFGETFQY
CCCCCCEEEEEEEEEECCCCCCCHHHHHHHHEECCCCCHHHHHHHHHCCCCCCCCCCEEC
SNFLVAAGGYAAGRAHSAYGGLEKAFESAIGELVFRPLAMNNSCLRQEDAMKGEAALPHA
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCC
TNFEGGVSRIPLSIEMSVQSVAPAGAAWSTALDLARYLMLELGKGRTPGGERVVGEEFLL
CCCCCCCEECCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
ERRIKGIKIDQNNSYGLGLIVSDDSGLQVIHHGGNTFGFSSDMYFLPERDLGLVVLTNVY
HHHCCCEEEECCCCCEEEEEEECCCCEEEEEECCCCCCCCCCEEECCCCCCCEEEEHHHH
QASMFLAAMRQRVFELTFGAEPKAEKTVAAAVKMRQDGVADLRARVNSDAASMAWVDELA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHC
GQFECAELGPCEISRRGEGYGIEFSEWGGELGCEIEPGGGRLLRILSPPWRGGLKFVVNT
CCEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCEEECCCCEEEEEECCCCCCCEEEEEEC
DLRTLTLDGGQSKYVFQKR
CEEEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Beta-Lactam; H2O [C]

Specific reaction: A Beta-Lactam + H2O = A Substituted Beta- Amino Acid. [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA