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The map label for this gene is emrK [H]

Identifier: 116625387

GI number: 116625387

Start: 7948881

End: 7950149

Strand: Reverse

Name: emrK [H]

Synonym: Acid_6332

Alternate gene names: 116625387

Gene position: 7950149-7948881 (Counterclockwise)

Preceding gene: 116625388

Following gene: 116625386

Centisome position: 79.78

GC content: 62.81

Gene sequence:

>1269_bases
ATGGCCGACACGTTGGTCGAGACGCCAAAGACGGAAACTCCACCGCCGCGCATCGTCAGAAAGCCAAAGCGCCACCGTGG
CGCGTTGATCGCAATGTTGGTGTTGTTGCCGCTCCTGGTGGGCGGTTACTTCCTATGGAAGTACCTTGGAACCTACGAAT
CGACCGATGACGCTCAGATCGATGGGCACATCCATGCCATCAGCGCCCGCATCAGCGGGCACATCAGCCAGGTGCTCGTC
GAGGACCAGCAGATTGTCAAAGCCGGCGACGTCCTGGTAGTGATCGACCCCCGAGACTATGACGTGGCCGTCGCCAAAGC
CGAGGCGGATGTCGCCGATGCCAGGGCCGCGCTGACCGGTTCGCAAACAGAGATTCCGATCACCTCGACCAATACCGCGA
GCACTCTGCAGACCGCGCAATCCACGCTCGCCGATAGCCGCGCCGGCCTGCTCTCCGCCCAGCGGCAGCTCAGCGCGGCC
GAGTCTCGCCTCGCGGCCGCCGAGGCGCAGGTGACGGAAGCCCAGGCCAACTACAAGAAAGCCGCGGACGACGAGCGGCG
CTACAAGCAGCTTGTGGACAAGGAGGAGATCTCGCAACAATTGTACGAACAGGCGGCGCAAGCGGCCGCCGCCGCCAAGG
CTACCGTGGATACGCGGATCGCCTCGGTGAACGAAGCGCGCCACAACGTGGCGGTCGCGGAAGCTGCGATTCAACAGGCG
CAGGCCAAAGTCCCACAGGCGGAAGCCTCCATCCAATCGGCCCTGACCGCGCCGCAGCAGGTTGCCATCAGCCGGTCGAA
GGCCAAGTCTTCGGAAGCGAAACTCGCGCAGCAGGCGGCCTTACTTGCCCAAGCCAGGTTGAACCAGAGCTATACCACCA
TCGTGGCTCCGGCGGCTGGGATCATCGGCAAAAAGACCGTGGAAGTGGGACAGAACGTATCGCCTGGCCAGCAACTCATG
GCCATTGTTCAACTCGACGATGTGTGGGTGATCGCCAATTTCAAGGAAACCCAGCTCCGCAGGATGCAGCCAGGCCAGCG
TGTGAGGTTCAGCGTGGACGCGTACAGCCGGGAGTACCAGGGACGCATTACCGGCATCGGGGGCGCCAGCGGGTCGCGCT
TCAGCCTGCTTCCGCCGGAGAATGCAACCGGGAATTACGTGAAGGTGGTGCAGCGCATTCCGGTTCGCATCGATCTCGAC
CCCGGTCAGAACGCCGATCATCACCTGCGTCCGGGAATGTCCGTTGATCCGAAGGTTTTCCTGCGATAG

Upstream 100 bases:

>100_bases
ATTTCCGCGTCGTACGCCCACAATCTTGCCAAGGCATCGCTGGCGCGCGCCTTGGGCCTGGCCGAGCAGGGGATCAAAAA
GTTGATTGAGGTGAAATGAA

Downstream 100 bases:

>100_bases
CGAATCGTTGGGTATATGGCCGAAGTAACCGAGACGCTCCCGCCGCCGGCACGCGCACCACAACGCTGGGAACCGAAGGC
CAATCCGTGGCTAATTGCCG

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MADTLVETPKTETPPPRIVRKPKRHRGALIAMLVLLPLLVGGYFLWKYLGTYESTDDAQIDGHIHAISARISGHISQVLV
EDQQIVKAGDVLVVIDPRDYDVAVAKAEADVADARAALTGSQTEIPITSTNTASTLQTAQSTLADSRAGLLSAQRQLSAA
ESRLAAAEAQVTEAQANYKKAADDERRYKQLVDKEEISQQLYEQAAQAAAAAKATVDTRIASVNEARHNVAVAEAAIQQA
QAKVPQAEASIQSALTAPQQVAISRSKAKSSEAKLAQQAALLAQARLNQSYTTIVAPAAGIIGKKTVEVGQNVSPGQQLM
AIVQLDDVWVIANFKETQLRRMQPGQRVRFSVDAYSREYQGRITGIGGASGSRFSLLPPENATGNYVKVVQRIPVRIDLD
PGQNADHHLRPGMSVDPKVFLR

Sequences:

>Translated_422_residues
MADTLVETPKTETPPPRIVRKPKRHRGALIAMLVLLPLLVGGYFLWKYLGTYESTDDAQIDGHIHAISARISGHISQVLV
EDQQIVKAGDVLVVIDPRDYDVAVAKAEADVADARAALTGSQTEIPITSTNTASTLQTAQSTLADSRAGLLSAQRQLSAA
ESRLAAAEAQVTEAQANYKKAADDERRYKQLVDKEEISQQLYEQAAQAAAAAKATVDTRIASVNEARHNVAVAEAAIQQA
QAKVPQAEASIQSALTAPQQVAISRSKAKSSEAKLAQQAALLAQARLNQSYTTIVAPAAGIIGKKTVEVGQNVSPGQQLM
AIVQLDDVWVIANFKETQLRRMQPGQRVRFSVDAYSREYQGRITGIGGASGSRFSLLPPENATGNYVKVVQRIPVRIDLD
PGQNADHHLRPGMSVDPKVFLR
>Mature_421_residues
ADTLVETPKTETPPPRIVRKPKRHRGALIAMLVLLPLLVGGYFLWKYLGTYESTDDAQIDGHIHAISARISGHISQVLVE
DQQIVKAGDVLVVIDPRDYDVAVAKAEADVADARAALTGSQTEIPITSTNTASTLQTAQSTLADSRAGLLSAQRQLSAAE
SRLAAAEAQVTEAQANYKKAADDERRYKQLVDKEEISQQLYEQAAQAAAAAKATVDTRIASVNEARHNVAVAEAAIQQAQ
AKVPQAEASIQSALTAPQQVAISRSKAKSSEAKLAQQAALLAQARLNQSYTTIVAPAAGIIGKKTVEVGQNVSPGQQLMA
IVQLDDVWVIANFKETQLRRMQPGQRVRFSVDAYSREYQGRITGIGGASGSRFSLLPPENATGNYVKVVQRIPVRIDLDP
GQNADHHLRPGMSVDPKVFLR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=396, Percent_Identity=33.3333333333333, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789041, Length=413, Percent_Identity=29.7820823244552, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1790519, Length=370, Percent_Identity=26.4864864864865, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI87081951, Length=141, Percent_Identity=31.2056737588652, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 45418; Mature: 45287

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTLVETPKTETPPPRIVRKPKRHRGALIAMLVLLPLLVGGYFLWKYLGTYESTDDAQI
CCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
DGHIHAISARISGHISQVLVEDQQIVKAGDVLVVIDPRDYDVAVAKAEADVADARAALTG
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCHHHHHHHHHCC
SQTEIPITSTNTASTLQTAQSTLADSRAGLLSAQRQLSAAESRLAAAEAQVTEAQANYKK
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AADDERRYKQLVDKEEISQQLYEQAAQAAAAAKATVDTRIASVNEARHNVAVAEAAIQQA
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAKVPQAEASIQSALTAPQQVAISRSKAKSSEAKLAQQAALLAQARLNQSYTTIVAPAAG
HHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHH
IIGKKTVEVGQNVSPGQQLMAIVQLDDVWVIANFKETQLRRMQPGQRVRFSVDAYSREYQ
HHCCHHHHHCCCCCCHHHEEEEEEECCEEEEECCHHHHHHHCCCCCEEEEEEHHHHHHHC
GRITGIGGASGSRFSLLPPENATGNYVKVVQRIPVRIDLDPGQNADHHLRPGMSVDPKVF
CEEEEECCCCCCEEEECCCCCCCCHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCEE
LR
CC
>Mature Secondary Structure 
ADTLVETPKTETPPPRIVRKPKRHRGALIAMLVLLPLLVGGYFLWKYLGTYESTDDAQI
CCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
DGHIHAISARISGHISQVLVEDQQIVKAGDVLVVIDPRDYDVAVAKAEADVADARAALTG
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCHHHHHHHHHCC
SQTEIPITSTNTASTLQTAQSTLADSRAGLLSAQRQLSAAESRLAAAEAQVTEAQANYKK
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AADDERRYKQLVDKEEISQQLYEQAAQAAAAAKATVDTRIASVNEARHNVAVAEAAIQQA
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAKVPQAEASIQSALTAPQQVAISRSKAKSSEAKLAQQAALLAQARLNQSYTTIVAPAAG
HHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHH
IIGKKTVEVGQNVSPGQQLMAIVQLDDVWVIANFKETQLRRMQPGQRVRFSVDAYSREYQ
HHCCHHHHHCCCCCCHHHEEEEEEECCEEEEECCHHHHHHHCCCCCEEEEEEHHHHHHHC
GRITGIGGASGSRFSLLPPENATGNYVKVVQRIPVRIDLDPGQNADHHLRPGMSVDPKVF
CEEEEECCCCCCEEEECCCCCCCCHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCEE
LR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]