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The map label for this gene is yccK [H]

Identifier: 116625366

GI number: 116625366

Start: 7927956

End: 7928945

Strand: Direct

Name: yccK [H]

Synonym: Acid_6311

Alternate gene names: 116625366

Gene position: 7927956-7928945 (Clockwise)

Preceding gene: 116625363

Following gene: 116625367

Centisome position: 79.55

GC content: 59.7

Gene sequence:

>990_bases
ATGAAGAACCGCCAACTCGGCCAAAGCAGTATCGAAGCGTCCGCAATCGGACTTGGATGTATGAGCATCGGAATTGCCGA
CGTGTACACCAGCAGTTCGCAGAGTGAGAGCGATGCCATTGCGCTTGTCCATCGCGCGCTGGATTTGGGCATCAACTTCC
TCGACACAGCGAATATCTATGGCGATTCGGAGATCAAGGTCGGCAAGGCTCTCCGAGGCCGGCGCGAGGGGGTCGTGCTG
GCAACCAAATTCGGGATTGTACCCGGTTCGTCCTATGAGAACAGGGCGGTCGATGGGAGTCCCGAAAATGCGCGCCGCTG
CTGCGAATTGTCGCTCCAACGCCTGGGAGTCGATCTGATCGATCTCTACTACTTGCATCGAGTTGATCCCAGCGTGCCGA
TTGAGGACACCGTCGGCGCCATGGCCGACCTCGTTCGAGCCGGGAAAGTGCGGCATATCGGACTTTCAGAAGCGTCTCCT
GCGACGGTGCGCCGCGCCCACAAAGTGCACCCGCTCACGGCGGTGCAGACCGAGTACTCACTGTTCACACGCGAAGCGGA
CGAAGTGCTCCCCACGCTACGCGAGCTTGGAATCTCGCTCGTTGCCTACAGCCCGCTGGGGCGCGGTTTTCTGGGTGCGC
GCTTTCGCAGCCTGGACGAACTCGCTCCGAATGACTGGCGCAGAAACAATCCCCGGTTCCAAGGAGAGCAATTTCAGCAC
AACCTCGCAGTCGCGGACATAGTCGCCGAGATCGCCCGCGAGAAGGGGGCAACGCCTGCCCAACTCGCACTCACCTGGGT
GCTTGCGCAAGGGGAAGACGTCGTTCCGATTCCCGGCACCAGCAGCGTGGAACGGCTTGAAGAAAACGTGAACTCACTCG
ACTTGATCCTCACATCAGATGACCTGGACCGACTGGAGCGAGCAGCGCCAAAGGGTGCCGTCAGCGGCGACCGTTATGAA
CCTGGAATGATGCAGTTGATCAACGGTTGA

Upstream 100 bases:

>100_bases
TCACGCGCGCGGTGTTCGTGAACCAGCTCACGACGATGGCATCGACATAATCCAACCTCACGAAACCAGACGGGCGATCG
TGGCATCCACTAACTACTCG

Downstream 100 bases:

>100_bases
AAGACCCAACGAGCAGGGCCTGTTGAACCGGTCCTTCTATCGGATAAGGAGGATTTCGATGACTCAAACACTAAGTAAGA
CTATGAAGGCTGTGGCGATT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKNRQLGQSSIEASAIGLGCMSIGIADVYTSSSQSESDAIALVHRALDLGINFLDTANIYGDSEIKVGKALRGRREGVVL
ATKFGIVPGSSYENRAVDGSPENARRCCELSLQRLGVDLIDLYYLHRVDPSVPIEDTVGAMADLVRAGKVRHIGLSEASP
ATVRRAHKVHPLTAVQTEYSLFTREADEVLPTLRELGISLVAYSPLGRGFLGARFRSLDELAPNDWRRNNPRFQGEQFQH
NLAVADIVAEIAREKGATPAQLALTWVLAQGEDVVPIPGTSSVERLEENVNSLDLILTSDDLDRLERAAPKGAVSGDRYE
PGMMQLING

Sequences:

>Translated_329_residues
MKNRQLGQSSIEASAIGLGCMSIGIADVYTSSSQSESDAIALVHRALDLGINFLDTANIYGDSEIKVGKALRGRREGVVL
ATKFGIVPGSSYENRAVDGSPENARRCCELSLQRLGVDLIDLYYLHRVDPSVPIEDTVGAMADLVRAGKVRHIGLSEASP
ATVRRAHKVHPLTAVQTEYSLFTREADEVLPTLRELGISLVAYSPLGRGFLGARFRSLDELAPNDWRRNNPRFQGEQFQH
NLAVADIVAEIAREKGATPAQLALTWVLAQGEDVVPIPGTSSVERLEENVNSLDLILTSDDLDRLERAAPKGAVSGDRYE
PGMMQLING
>Mature_329_residues
MKNRQLGQSSIEASAIGLGCMSIGIADVYTSSSQSESDAIALVHRALDLGINFLDTANIYGDSEIKVGKALRGRREGVVL
ATKFGIVPGSSYENRAVDGSPENARRCCELSLQRLGVDLIDLYYLHRVDPSVPIEDTVGAMADLVRAGKVRHIGLSEASP
ATVRRAHKVHPLTAVQTEYSLFTREADEVLPTLRELGISLVAYSPLGRGFLGARFRSLDELAPNDWRRNNPRFQGEQFQH
NLAVADIVAEIAREKGATPAQLALTWVLAQGEDVVPIPGTSSVERLEENVNSLDLILTSDDLDRLERAAPKGAVSGDRYE
PGMMQLING

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=315, Percent_Identity=27.9365079365079, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4504825, Length=312, Percent_Identity=27.8846153846154, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI27436964, Length=336, Percent_Identity=27.9761904761905, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI27436966, Length=336, Percent_Identity=27.6785714285714, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI27436962, Length=336, Percent_Identity=27.6785714285714, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI27436971, Length=317, Percent_Identity=28.7066246056782, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI223718702, Length=284, Percent_Identity=30.6338028169014, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI41327764, Length=281, Percent_Identity=29.8932384341637, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI41152114, Length=216, Percent_Identity=30.0925925925926, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI87081735, Length=325, Percent_Identity=35.0769230769231, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788070, Length=323, Percent_Identity=35.2941176470588, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789375, Length=343, Percent_Identity=29.7376093294461, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789199, Length=352, Percent_Identity=32.3863636363636, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788081, Length=311, Percent_Identity=28.9389067524116, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787674, Length=309, Percent_Identity=28.4789644012945, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI48994888, Length=291, Percent_Identity=28.8659793814433, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17564128, Length=307, Percent_Identity=24.4299674267101, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323998, Length=330, Percent_Identity=28.1818181818182, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6325384, Length=346, Percent_Identity=26.3005780346821, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=304, Percent_Identity=26.9736842105263, Blast_Score=106, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=27.0029673590504, Blast_Score=102, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6319951, Length=331, Percent_Identity=27.190332326284, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=263, Percent_Identity=26.615969581749, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24640980, Length=340, Percent_Identity=25.2941176470588, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45549126, Length=340, Percent_Identity=25.2941176470588, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI20129731, Length=319, Percent_Identity=28.5266457680251, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646159, Length=320, Percent_Identity=26.5625, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24657054, Length=329, Percent_Identity=25.2279635258359, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646155, Length=290, Percent_Identity=26.8965517241379, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35702; Mature: 35702

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRQLGQSSIEASAIGLGCMSIGIADVYTSSSQSESDAIALVHRALDLGINFLDTANIY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCC
GDSEIKVGKALRGRREGVVLATKFGIVPGSSYENRAVDGSPENARRCCELSLQRLGVDLI
CCCCEEHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHH
DLYYLHRVDPSVPIEDTVGAMADLVRAGKVRHIGLSEASPATVRRAHKVHPLTAVQTEYS
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHH
LFTREADEVLPTLRELGISLVAYSPLGRGFLGARFRSLDELAPNDWRRNNPRFQGEQFQH
HHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
NLAVADIVAEIAREKGATPAQLALTWVLAQGEDVVPIPGTSSVERLEENVNSLDLILTSD
HHHHHHHHHHHHHHCCCCHHHHHHEEEEECCCCEEECCCCHHHHHHHHCCCCEEEEEECC
DLDRLERAAPKGAVSGDRYEPGMMQLING
HHHHHHHHCCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MKNRQLGQSSIEASAIGLGCMSIGIADVYTSSSQSESDAIALVHRALDLGINFLDTANIY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCC
GDSEIKVGKALRGRREGVVLATKFGIVPGSSYENRAVDGSPENARRCCELSLQRLGVDLI
CCCCEEHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHH
DLYYLHRVDPSVPIEDTVGAMADLVRAGKVRHIGLSEASPATVRRAHKVHPLTAVQTEYS
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHH
LFTREADEVLPTLRELGISLVAYSPLGRGFLGARFRSLDELAPNDWRRNNPRFQGEQFQH
HHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
NLAVADIVAEIAREKGATPAQLALTWVLAQGEDVVPIPGTSSVERLEENVNSLDLILTSD
HHHHHHHHHHHHHHCCCCHHHHHHEEEEECCCCEEECCCCHHHHHHHHCCCCEEEEEECC
DLDRLERAAPKGAVSGDRYEPGMMQLING
HHHHHHHHCCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]