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The map label for this gene is nhaA1 [H]

Identifier: 116625220

GI number: 116625220

Start: 7725843

End: 7726877

Strand: Reverse

Name: nhaA1 [H]

Synonym: Acid_6165

Alternate gene names: 116625220

Gene position: 7726877-7725843 (Counterclockwise)

Preceding gene: 116625221

Following gene: 116625219

Centisome position: 77.54

GC content: 59.23

Gene sequence:

>1035_bases
ATGAAACTATCTCTCACTCTCAGTCTGATCCCGCTGCTCGTTTGCGCTCTTAGCACCGCTCGCGCAAGCGACACCGGCAC
GCCATCCGGCAGCACAGTCGTCGTCGATATCGACGGCGTCAAGTTGACGGCGGACGATGTCGAGCAAAAACTCCCGGGGC
GCCTGCTGCAAGCGCGCGCCACATACTACCAGACCGAACGCAAAACTGTTGACGAATTCATCGAGACGTACCTGCTGGAC
CGAGCGGCGAAAGCAGAGAACCTGACGGTGGACGCGTTGTTGGAGCGTCATGTCAACAGCGCGATCGCGAAGGACCCCAG
CGAGGAAACGCTGCGGATTTATTACGAAGTGGTCAACACCACAGAGCCGTATGAGAAGGTCCGGCCGCAGATCGTCGAGC
GCATTCGCCAGGTGCGAATCGCCAAATTGAAGGCCGCCTATGTGGAATCTCTGCGGGCCAAATCGAATGTGGCGATTCTG
CTTCCGGCGCCCCGAGCCAAAGTTTCGCTGGCCGGCGCTCCGGTTCGCGGCGCGGCGGACGCACCGGTTGTGCTGGTGGA
ATATGCCGATTATGAGTGCCCGTACTGCCAGATGGTTCAGCCGGCCCTGGACAAAGTGCTGGGCGACTACAAAGGCAAGG
TAGCCTTTGCGTTCAAAGATGTCCCGCTGCCGATGCACGCCAACGCCATTAAGGCCGCTGAAGCAACGCGCTGCGCCGAG
GCGCAGGGAAAGTATTGGGAATACCACGATCTCTTGTTCAGCACCAAGATGGTCGAACCGGCGAGGCTGAAGGAACACGC
GCGTACGCTTAAGCTCGATACCGCGGCCTTCGATACGTGCCTCGATTCCGGAGCCAAGTCCGACTCGATTAAGACTGCAT
TGAATGAAGCGCAGGACCTGGGTCTGAACAGCACGCCCAGCTTCTTCATCAACGGCCGCTTCACCCAAGGGAACCTCAGT
TACGAACAGCTTCGCCAGATTATCGACGAGGAACTGGCCCTGGTTCCCGCACGCCGCGCGGCAAATCAGCCGTAA

Upstream 100 bases:

>100_bases
ATTCGATTCTCGGGTAACCGGCCTAAACCGGTTACCCGAGGTATTTGAAGCACACACACCTTCCGCCATTTCACCTTAAC
GAAAGCGAGACCTCGGGTAT

Downstream 100 bases:

>100_bases
GCGCCAGCCATCCGCAGTAGTTTGTTTTCTGGCCGCTCCCCGCCCCACCGGCAGGGAGCGGCCATGTCACCAATTACGCA
GGTCAAACCTTAGGCTATTT

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 1 [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKLSLTLSLIPLLVCALSTARASDTGTPSGSTVVVDIDGVKLTADDVEQKLPGRLLQARATYYQTERKTVDEFIETYLLD
RAAKAENLTVDALLERHVNSAIAKDPSEETLRIYYEVVNTTEPYEKVRPQIVERIRQVRIAKLKAAYVESLRAKSNVAIL
LPAPRAKVSLAGAPVRGAADAPVVLVEYADYECPYCQMVQPALDKVLGDYKGKVAFAFKDVPLPMHANAIKAAEATRCAE
AQGKYWEYHDLLFSTKMVEPARLKEHARTLKLDTAAFDTCLDSGAKSDSIKTALNEAQDLGLNSTPSFFINGRFTQGNLS
YEQLRQIIDEELALVPARRAANQP

Sequences:

>Translated_344_residues
MKLSLTLSLIPLLVCALSTARASDTGTPSGSTVVVDIDGVKLTADDVEQKLPGRLLQARATYYQTERKTVDEFIETYLLD
RAAKAENLTVDALLERHVNSAIAKDPSEETLRIYYEVVNTTEPYEKVRPQIVERIRQVRIAKLKAAYVESLRAKSNVAIL
LPAPRAKVSLAGAPVRGAADAPVVLVEYADYECPYCQMVQPALDKVLGDYKGKVAFAFKDVPLPMHANAIKAAEATRCAE
AQGKYWEYHDLLFSTKMVEPARLKEHARTLKLDTAAFDTCLDSGAKSDSIKTALNEAQDLGLNSTPSFFINGRFTQGNLS
YEQLRQIIDEELALVPARRAANQP
>Mature_344_residues
MKLSLTLSLIPLLVCALSTARASDTGTPSGSTVVVDIDGVKLTADDVEQKLPGRLLQARATYYQTERKTVDEFIETYLLD
RAAKAENLTVDALLERHVNSAIAKDPSEETLRIYYEVVNTTEPYEKVRPQIVERIRQVRIAKLKAAYVESLRAKSNVAIL
LPAPRAKVSLAGAPVRGAADAPVVLVEYADYECPYCQMVQPALDKVLGDYKGKVAFAFKDVPLPMHANAIKAAEATRCAE
AQGKYWEYHDLLFSTKMVEPARLKEHARTLKLDTAAFDTCLDSGAKSDSIKTALNEAQDLGLNSTPSFFINGRFTQGNLS
YEQLRQIIDEELALVPARRAANQP

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 37903; Mature: 37903

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSLTLSLIPLLVCALSTARASDTGTPSGSTVVVDIDGVKLTADDVEQKLPGRLLQARA
CEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEECHHHHHHHCCHHHHHHHH
TYYQTERKTVDEFIETYLLDRAAKAENLTVDALLERHVNSAIAKDPSEETLRIYYEVVNT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
TEPYEKVRPQIVERIRQVRIAKLKAAYVESLRAKSNVAILLPAPRAKVSLAGAPVRGAAD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCC
APVVLVEYADYECPYCQMVQPALDKVLGDYKGKVAFAFKDVPLPMHANAIKAAEATRCAE
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
AQGKYWEYHDLLFSTKMVEPARLKEHARTLKLDTAAFDTCLDSGAKSDSIKTALNEAQDL
HCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GLNSTPSFFINGRFTQGNLSYEQLRQIIDEELALVPARRAANQP
CCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHCCCCC
>Mature Secondary Structure
MKLSLTLSLIPLLVCALSTARASDTGTPSGSTVVVDIDGVKLTADDVEQKLPGRLLQARA
CEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEECHHHHHHHCCHHHHHHHH
TYYQTERKTVDEFIETYLLDRAAKAENLTVDALLERHVNSAIAKDPSEETLRIYYEVVNT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
TEPYEKVRPQIVERIRQVRIAKLKAAYVESLRAKSNVAILLPAPRAKVSLAGAPVRGAAD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCC
APVVLVEYADYECPYCQMVQPALDKVLGDYKGKVAFAFKDVPLPMHANAIKAAEATRCAE
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
AQGKYWEYHDLLFSTKMVEPARLKEHARTLKLDTAAFDTCLDSGAKSDSIKTALNEAQDL
HCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GLNSTPSFFINGRFTQGNLSYEQLRQIIDEELALVPARRAANQP
CCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA