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The map label for this gene is ntcA [H]

Identifier: 116625216

GI number: 116625216

Start: 7709262

End: 7709984

Strand: Reverse

Name: ntcA [H]

Synonym: Acid_6161

Alternate gene names: 116625216

Gene position: 7709984-7709262 (Counterclockwise)

Preceding gene: 116625217

Following gene: 116625215

Centisome position: 77.37

GC content: 58.09

Gene sequence:

>723_bases
ATGACATCCAGCTCAGGCGGCAGTGCAACCCAGAAGTCTCTGGTAGATCCCTTGGCATTCCTGCCGTGTTCCACAGTGGC
GGAATTCAAAAAGGGACGGATCATCTATGAGTACGACCAGCCTTGCGAGAATCTTTATCTGATTCTCTCCGGGACCATCA
AGGTCTCCCGCATGGTCGATGTGGGCGGGCAATTGCTGCTGGATCTCTATCGGGCAGACGATTTCTTTGGAGACCTGGCA
CTGCTGAATCCATCGGTCACCGCCGAGCAGGCCGTGGCCTACGCCACTTCATCCGTGATGATCTGGCGGACTTCGGACAT
TGAGGAAATCGTTATGGCGCGGCCGAAGCTCGGCATCGCGCTGCTTCAGTCATTTGGCCAGCGCTCACTCGGCTTCATTC
AGCGCGTGGAAAGCCTGTGCTTCGAATCCATCGAACATCGACTGGCGCGATCCCTGATCCGCTTCGCCGACCATTTGGGT
GCAGCGCAGCCGGACGGCACCGTGCTCATGGAACCCCTGACCCATGAACTTCTCTCCCAGTACATCGGCACCTCACGCGA
GGTGGTCACCTGCCACATGACCAATCTTCGCCGGCTGGGATTTCTTCAGTATTCGCGTAAAATGATCGTCATCCACCGCG
AGTCCATGAAGACGTGGCTGGACCGCGCCGCGAATAACGCTGCCCGCTCGCAAAAACCCCGAAAGGCCGGCGCCGACGCC
TAA

Upstream 100 bases:

>100_bases
AACTAAGTTTGTTGCGGCCTGTATTCAGCTAAGACGAAGCATCGTCACTTCGCTCCCGGCATATTTGCTTGCTCAATAAT
CCGAAAAAGGGAGTTTCAAA

Downstream 100 bases:

>100_bases
TAGCGCACTGGGTGATATGGCGACGCCAACCCGGTAAGTAGTACCGACGCTCTATGCCATCTTTCTGTGTTTTCATAGCC
TTAGACGCAAGGTCCGAGAA

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTSSSGGSATQKSLVDPLAFLPCSTVAEFKKGRIIYEYDQPCENLYLILSGTIKVSRMVDVGGQLLLDLYRADDFFGDLA
LLNPSVTAEQAVAYATSSVMIWRTSDIEEIVMARPKLGIALLQSFGQRSLGFIQRVESLCFESIEHRLARSLIRFADHLG
AAQPDGTVLMEPLTHELLSQYIGTSREVVTCHMTNLRRLGFLQYSRKMIVIHRESMKTWLDRAANNAARSQKPRKAGADA

Sequences:

>Translated_240_residues
MTSSSGGSATQKSLVDPLAFLPCSTVAEFKKGRIIYEYDQPCENLYLILSGTIKVSRMVDVGGQLLLDLYRADDFFGDLA
LLNPSVTAEQAVAYATSSVMIWRTSDIEEIVMARPKLGIALLQSFGQRSLGFIQRVESLCFESIEHRLARSLIRFADHLG
AAQPDGTVLMEPLTHELLSQYIGTSREVVTCHMTNLRRLGFLQYSRKMIVIHRESMKTWLDRAANNAARSQKPRKAGADA
>Mature_239_residues
TSSSGGSATQKSLVDPLAFLPCSTVAEFKKGRIIYEYDQPCENLYLILSGTIKVSRMVDVGGQLLLDLYRADDFFGDLAL
LNPSVTAEQAVAYATSSVMIWRTSDIEEIVMARPKLGIALLQSFGQRSLGFIQRVESLCFESIEHRLARSLIRFADHLGA
AQPDGTVLMEPLTHELLSQYIGTSREVVTCHMTNLRRLGFLQYSRKMIVIHRESMKTWLDRAANNAARSQKPRKAGADA

Specific function: Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR022299
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26690; Mature: 26559

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSSGGSATQKSLVDPLAFLPCSTVAEFKKGRIIYEYDQPCENLYLILSGTIKVSRMVD
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCCCEEEEEECCEEEHHHHH
VGGQLLLDLYRADDFFGDLALLNPSVTAEQAVAYATSSVMIWRTSDIEEIVMARPKLGIA
CCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCEEEEEECCCHHHHHHCCCCHHHH
LLQSFGQRSLGFIQRVESLCFESIEHRLARSLIRFADHLGAAQPDGTVLMEPLTHELLSQ
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHH
YIGTSREVVTCHMTNLRRLGFLQYSRKMIVIHRESMKTWLDRAANNAARSQKPRKAGADA
HHCCCCEEEEEEHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TSSSGGSATQKSLVDPLAFLPCSTVAEFKKGRIIYEYDQPCENLYLILSGTIKVSRMVD
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCCCEEEEEECCEEEHHHHH
VGGQLLLDLYRADDFFGDLALLNPSVTAEQAVAYATSSVMIWRTSDIEEIVMARPKLGIA
CCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCEEEEEECCCHHHHHHCCCCHHHH
LLQSFGQRSLGFIQRVESLCFESIEHRLARSLIRFADHLGAAQPDGTVLMEPLTHELLSQ
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHH
YIGTSREVVTCHMTNLRRLGFLQYSRKMIVIHRESMKTWLDRAANNAARSQKPRKAGADA
HHCCCCEEEEEEHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1630321 [H]