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The map label for this gene is apbE [H]

Identifier: 116625205

GI number: 116625205

Start: 7690011

End: 7690976

Strand: Direct

Name: apbE [H]

Synonym: Acid_6150

Alternate gene names: 116625205

Gene position: 7690011-7690976 (Clockwise)

Preceding gene: 116625204

Following gene: 116625209

Centisome position: 77.17

GC content: 63.35

Gene sequence:

>966_bases
ATGCGCCTCTCGTTCCTCGTCTTCTGCCTGCCGCTACTTCTTCATGCGCGCGACCCGGTGCGTGTCGAAGTGGAGGACGA
GGCGATGGGGACCACATTCGCGCTAACCCTTTACGGAGTGGACCGCACCGCTCTCAATGCGGCCGCCGCATCGGCCTTCA
TCGAATTGCACCGGCTGGACGGTATGCTCTCGAACTACCGGCCGGAGAGCGAATGGAGCGCGGTGAATCGCAGCGCCGCG
CTTCGTCCGGTCCGCGTTTCACCTGAGTTGTTCCACTTGCTTACGGAATGCCTTCGGTACGGCCGTGAAAGCGACGGCGC
CTTCGATATCACGGTGGGCCCGCTGATGAAGATCTGGGGCTTCTATAAAGGCGAGGGCCTGCTCCCGCGAAAGACGGAGA
TCACTACCGCGCTCCGCCTGGTAGGATACGCGCACGTGCAGCTCGACGCCGCCTCGCAGTCCGTGAGCTTCGACCAATCC
GGTGTCGAACTCGATCCCGGCGGCATCGGCAAAGGCTACGCGGTGGACAACATGGTGGCTGTTCTGAAGGCTCATGGAGT
GGGGACGGCGCTCGTGTCCGCGGGCGGCAGCAGCATTTACGGGTTGGGCGCGCCGCCGGAAACTCCGGCCGGATGGAAAG
TCCGGATTCGAGCGCCAGACGATCCTCGCCGTACGGCGGCGGAAGTCGTGCTGAAGGACATGTCGCTCTCGACCTCGGGC
GGTTACGAGAAGTTCTTCCTCGCGGAAGGGCGGACCTACTCACACATTATGAATCCGCGAACCGGATATCCCGCGCAAGG
GACGTCGTCCGTCTCCGTCGTCGCACCCCGCACGATCGATGGCGAAGTTTGGGCCAAGCCCTACTTCGTCCTCGGCCGCG
CGTGGACCGCGGCGCACCGGCCCAAGGACTTCAAGATCTTTCTTTGCGATGACACCAGCCGGCATACCTGCGCCTGGATT
CCTTGA

Upstream 100 bases:

>100_bases
GCTTCGGAGACGAACCACCGGTGCGCACCACCATCGCCGCCGCGGGCGGAATCCCGGGCAATTCGCTGGTGGAGATCGAC
GTCATCGCTTACATCTAGGG

Downstream 100 bases:

>100_bases
GACCCTTCACATCACCCGACGATATTACTGTGCATTTGTCTGCTCGCAGGCCACGAAGAATTCCCGAGCTAACAAGCCGC
GACCGTCAGGGAGCGCAACG

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MRLSFLVFCLPLLLHARDPVRVEVEDEAMGTTFALTLYGVDRTALNAAAASAFIELHRLDGMLSNYRPESEWSAVNRSAA
LRPVRVSPELFHLLTECLRYGRESDGAFDITVGPLMKIWGFYKGEGLLPRKTEITTALRLVGYAHVQLDAASQSVSFDQS
GVELDPGGIGKGYAVDNMVAVLKAHGVGTALVSAGGSSIYGLGAPPETPAGWKVRIRAPDDPRRTAAEVVLKDMSLSTSG
GYEKFFLAEGRTYSHIMNPRTGYPAQGTSSVSVVAPRTIDGEVWAKPYFVLGRAWTAAHRPKDFKIFLCDDTSRHTCAWI
P

Sequences:

>Translated_321_residues
MRLSFLVFCLPLLLHARDPVRVEVEDEAMGTTFALTLYGVDRTALNAAAASAFIELHRLDGMLSNYRPESEWSAVNRSAA
LRPVRVSPELFHLLTECLRYGRESDGAFDITVGPLMKIWGFYKGEGLLPRKTEITTALRLVGYAHVQLDAASQSVSFDQS
GVELDPGGIGKGYAVDNMVAVLKAHGVGTALVSAGGSSIYGLGAPPETPAGWKVRIRAPDDPRRTAAEVVLKDMSLSTSG
GYEKFFLAEGRTYSHIMNPRTGYPAQGTSSVSVVAPRTIDGEVWAKPYFVLGRAWTAAHRPKDFKIFLCDDTSRHTCAWI
P
>Mature_321_residues
MRLSFLVFCLPLLLHARDPVRVEVEDEAMGTTFALTLYGVDRTALNAAAASAFIELHRLDGMLSNYRPESEWSAVNRSAA
LRPVRVSPELFHLLTECLRYGRESDGAFDITVGPLMKIWGFYKGEGLLPRKTEITTALRLVGYAHVQLDAASQSVSFDQS
GVELDPGGIGKGYAVDNMVAVLKAHGVGTALVSAGGSSIYGLGAPPETPAGWKVRIRAPDDPRRTAAEVVLKDMSLSTSG
GYEKFFLAEGRTYSHIMNPRTGYPAQGTSSVSVVAPRTIDGEVWAKPYFVLGRAWTAAHRPKDFKIFLCDDTSRHTCAWI
P

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=302, Percent_Identity=30.4635761589404, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 34964; Mature: 34964

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSFLVFCLPLLLHARDPVRVEVEDEAMGTTFALTLYGVDRTALNAAAASAFIELHRLD
CCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHH
GMLSNYRPESEWSAVNRSAALRPVRVSPELFHLLTECLRYGRESDGAFDITVGPLMKIWG
HHHHCCCCCHHHHHHCHHHCCCEEECCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHH
FYKGEGLLPRKTEITTALRLVGYAHVQLDAASQSVSFDQSGVELDPGGIGKGYAVDNMVA
HCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCEECCCCCCCCCHHHHHHH
VLKAHGVGTALVSAGGSSIYGLGAPPETPAGWKVRIRAPDDPRRTAAEVVLKDMSLSTSG
HHHHCCCCEEEECCCCCEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCC
GYEKFFLAEGRTYSHIMNPRTGYPAQGTSSVSVVAPRTIDGEVWAKPYFVLGRAWTAAHR
CCEEEEEECCCCHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHCCCEEEEECEEHHCCC
PKDFKIFLCDDTSRHTCAWIP
CCCCEEEEECCCCCCEEECCC
>Mature Secondary Structure
MRLSFLVFCLPLLLHARDPVRVEVEDEAMGTTFALTLYGVDRTALNAAAASAFIELHRLD
CCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHH
GMLSNYRPESEWSAVNRSAALRPVRVSPELFHLLTECLRYGRESDGAFDITVGPLMKIWG
HHHHCCCCCHHHHHHCHHHCCCEEECCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHH
FYKGEGLLPRKTEITTALRLVGYAHVQLDAASQSVSFDQSGVELDPGGIGKGYAVDNMVA
HCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCEECCCCCCCCCHHHHHHH
VLKAHGVGTALVSAGGSSIYGLGAPPETPAGWKVRIRAPDDPRRTAAEVVLKDMSLSTSG
HHHHCCCCEEEECCCCCEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCC
GYEKFFLAEGRTYSHIMNPRTGYPAQGTSSVSVVAPRTIDGEVWAKPYFVLGRAWTAAHR
CCEEEEEECCCCHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHCCCEEEEECEEHHCCC
PKDFKIFLCDDTSRHTCAWIP
CCCCEEEEECCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]