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The map label for this gene is apbE [H]

Identifier: 116625198

GI number: 116625198

Start: 7682054

End: 7683082

Strand: Reverse

Name: apbE [H]

Synonym: Acid_6143

Alternate gene names: 116625198

Gene position: 7683082-7682054 (Counterclockwise)

Preceding gene: 116625199

Following gene: 116625195

Centisome position: 77.1

GC content: 66.76

Gene sequence:

>1029_bases
GTGTTGAGGACGATCAGTAGCGCGGGCCGCGCGGCGGCGATCTGGCTGGTCTGGTCAGGCTGCGCGCCGGCCTCGGACCT
GCGCCTGTACGAATCCGTGGAGCCGCACATGGGCACGTTGGTGCGTATCAAGCTCTACGCCGAATCGGACCAGCAAGCCG
CACCGGCATTTCGCGCGGCCTTCGACCGCATCGCGCAGCTCGACTCGGCACTCTCCGATTACAAGCCGGATAGCGAGCTA
AACCGGGTATGCCGCAGCCCTGCCGGTCATCCGGTCAAAGCGGATCCGGATCTGTTTCGCGTGCTGGCGGCATCGGTCGC
GCTCTCCGAGGAGACTGGCGGCGCTTTCGATGTCACGCTGGGACCGGTGATCCGGTTGTGGCGACGAGCGCGGCTCGATC
ACCGGCTGCCTTCATCCGAGGCACTGGCCGATGCCGCGTCGCGATCGGGATATCGCAAACTGCACCTCGACGCGTCCGCT
CGAACGGTGATGCTGGACCTTCCCGGTATGCAACTCGATCTCGGCGCGATTGCAAAAGGCTACGCCGCCGATGCTGCATT
ATCGTTGCTGGCGGACCTCGGGATCCGGCGCGCGCTGGTCGCCGCCAGCGGGGATCTGGCGATCGGCGATCCCCCACCCG
GCCGGCGCGGATGGCGGGTTGGTGTGGATCCCCGCGGTTCCGACGACGGATTCGAGCGGGTCCTGGAATTGAGCAATGCA
GCGGTTTCCACCTCGGGCGACGCGGAGCAGTACCTGGAGATCGGAGGCCAACGGTACTCTCACATCGTCGATCCGGCGAC
GAACATCGGCATCACACGCCCGATCGCAGTGACAGTTGTGGCCGCGAAGGGAATCGATGCCGACTCGCTGGCGACGGCCG
TCAGCGTTCTCGGTGCGGAGAGGGGGCTCGCCCTCATCCGGAGACATCCGGGCGCGGAGGTGTTCATCGTTACCGGCTCG
AGCGCGGCGGGGCGCGTGGTCGAATCGCCTGGTTGGGCGCGGCTCAGTCAGCCGCTTCCGTTGCGGTGA

Upstream 100 bases:

>100_bases
AGCATCTGGTACGAGACGGACGCACAATGGCTGGGATTCCGTCTGGTGCGTCCCGCAAAGCTTCCTACCCTGGACGAGAT
GTATCGCTACTGGAACAGCG

Downstream 100 bases:

>100_bases
CAACGTTGCCCTGCCAAGGGCTCCGCCGGTTCTGGCATACTCTCATGCATGACACGTAGACAGGTACTGGCTGCTCCGCT
TGCGGCCGCGGCGTTTTCAG

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLRTISSAGRAAAIWLVWSGCAPASDLRLYESVEPHMGTLVRIKLYAESDQQAAPAFRAAFDRIAQLDSALSDYKPDSEL
NRVCRSPAGHPVKADPDLFRVLAASVALSEETGGAFDVTLGPVIRLWRRARLDHRLPSSEALADAASRSGYRKLHLDASA
RTVMLDLPGMQLDLGAIAKGYAADAALSLLADLGIRRALVAASGDLAIGDPPPGRRGWRVGVDPRGSDDGFERVLELSNA
AVSTSGDAEQYLEIGGQRYSHIVDPATNIGITRPIAVTVVAAKGIDADSLATAVSVLGAERGLALIRRHPGAEVFIVTGS
SAAGRVVESPGWARLSQPLPLR

Sequences:

>Translated_342_residues
MLRTISSAGRAAAIWLVWSGCAPASDLRLYESVEPHMGTLVRIKLYAESDQQAAPAFRAAFDRIAQLDSALSDYKPDSEL
NRVCRSPAGHPVKADPDLFRVLAASVALSEETGGAFDVTLGPVIRLWRRARLDHRLPSSEALADAASRSGYRKLHLDASA
RTVMLDLPGMQLDLGAIAKGYAADAALSLLADLGIRRALVAASGDLAIGDPPPGRRGWRVGVDPRGSDDGFERVLELSNA
AVSTSGDAEQYLEIGGQRYSHIVDPATNIGITRPIAVTVVAAKGIDADSLATAVSVLGAERGLALIRRHPGAEVFIVTGS
SAAGRVVESPGWARLSQPLPLR
>Mature_342_residues
MLRTISSAGRAAAIWLVWSGCAPASDLRLYESVEPHMGTLVRIKLYAESDQQAAPAFRAAFDRIAQLDSALSDYKPDSEL
NRVCRSPAGHPVKADPDLFRVLAASVALSEETGGAFDVTLGPVIRLWRRARLDHRLPSSEALADAASRSGYRKLHLDASA
RTVMLDLPGMQLDLGAIAKGYAADAALSLLADLGIRRALVAASGDLAIGDPPPGRRGWRVGVDPRGSDDGFERVLELSNA
AVSTSGDAEQYLEIGGQRYSHIVDPATNIGITRPIAVTVVAAKGIDADSLATAVSVLGAERGLALIRRHPGAEVFIVTGS
SAAGRVVESPGWARLSQPLPLR

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=273, Percent_Identity=30.4029304029304, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 36138; Mature: 36138

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTISSAGRAAAIWLVWSGCAPASDLRLYESVEPHMGTLVRIKLYAESDQQAAPAFRAA
CCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHH
FDRIAQLDSALSDYKPDSELNRVCRSPAGHPVKADPDLFRVLAASVALSEETGGAFDVTL
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEHH
GPVIRLWRRARLDHRLPSSEALADAASRSGYRKLHLDASARTVMLDLPGMQLDLGAIAKG
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCEEEHHHHHCC
YAADAALSLLADLGIRRALVAASGDLAIGDPPPGRRGWRVGVDPRGSDDGFERVLELSNA
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEECCCCCCCCHHHHHHHHHHCC
AVSTSGDAEQYLEIGGQRYSHIVDPATNIGITRPIAVTVVAAKGIDADSLATAVSVLGAE
CCCCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
RGLALIRRHPGAEVFIVTGSSAAGRVVESPGWARLSQPLPLR
HCHHHHHCCCCCEEEEEECCCCCCCEECCCCCHHCCCCCCCC
>Mature Secondary Structure
MLRTISSAGRAAAIWLVWSGCAPASDLRLYESVEPHMGTLVRIKLYAESDQQAAPAFRAA
CCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHH
FDRIAQLDSALSDYKPDSELNRVCRSPAGHPVKADPDLFRVLAASVALSEETGGAFDVTL
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEHH
GPVIRLWRRARLDHRLPSSEALADAASRSGYRKLHLDASARTVMLDLPGMQLDLGAIAKG
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCEEEHHHHHCC
YAADAALSLLADLGIRRALVAASGDLAIGDPPPGRRGWRVGVDPRGSDDGFERVLELSNA
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEECCCCCCCCHHHHHHHHHHCC
AVSTSGDAEQYLEIGGQRYSHIVDPATNIGITRPIAVTVVAAKGIDADSLATAVSVLGAE
CCCCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
RGLALIRRHPGAEVFIVTGSSAAGRVVESPGWARLSQPLPLR
HCHHHHHCCCCCEEEEEECCCCCCCEECCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]