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The map label for this gene is ybhS [H]

Identifier: 116625061

GI number: 116625061

Start: 7515607

End: 7516737

Strand: Direct

Name: ybhS [H]

Synonym: Acid_5991

Alternate gene names: 116625061

Gene position: 7515607-7516737 (Clockwise)

Preceding gene: 116625060

Following gene: 116625062

Centisome position: 75.42

GC content: 61.72

Gene sequence:

>1131_bases
ATGAGCTACCGGCGGCTGAAGGCGATCTGCGTCAAGGAACTGCATCACATCACGCGCGATTCGCGCAGCCTGACGATGGC
GCTGGCGGTGCCGGTGATGATGCTGTTGCTGTTCGGTTTCGCGCTGAGCCTGGACGTGGACCGGGTGCCGACTATGATCC
ACGACCAGGACCAGACGGCGGCCAGCCGGGCTCTGGTCCGCGAATTTCAGGGCTCGCGATTTTTCGACGTGCACATGGTA
AGCGATGACGCGATCATCGAGCGCGCGATCGATCGCAGCCAGACGCTGATGGGTGTGGTGATTCCGCGCGACTATTCGCA
GCAACTGGGCGCGGGGCGAACGGCGCAGGTACAGATTCTGCTGGATGGCAGCGATTCGAACACGGCCTCGATCGCGCTGG
GTTACGCGGAATCGCTGGTGCGGGGCTACTCGCTCGAATTGCGGAGGGGGGCGCTCAATCGCCGCGGCGGGGAACGCCTG
GCGCCGCCGGTGGATGCGCGCATGCGCGTCTGGTACAACAGCTCGCTGGAATCGAAGAATTACGTGGTCCCCGGATTGAT
CGCGGTGATCCTGCAGATCATCGCGGCGATGTTGACCTCGCTGACGATCGCGCGCGAGTGGGAGATGGGGACGATGGAGC
AACTGCTCTCCACGCCGCTGCGGCCTGCGGAGCTGGTGCTGGGCAAAATGATGGCGTACTTCGCGGTGGGCGTGGCGGAC
GCGGCGATCGCGGTGCTGGTGGGGATCGTCGTGTTCGGCGTGCCGTTCCGCGGGAGCTATCTGCTGCTGGCGGTTTCCAC
GTGTATCTTCCTGTTCGGCGCGCTGTTCTGGGGAATCTTCGTTTCGGCGGCGGCGAAATCGCAACTGCAGGCCTACCAGA
TGGGAATTTTGAGCTCGTTTCTGCCGGCCTTCATGCTATCCGGATTCATCTATTCGATCGAGACTATGCCGGCGCCGATC
CGTTTCATTACCCGCATCGTGCCCGCGCGATACGTGGTCACGATTTTGAAAGGACTCTTCCTGAAGGGCGTGGGCTTGAG
CGTGCTGTGGCAGGAACTGATGTTTCTGACGCTATACGCACTGATCATGTTCCTGATGGCGACACGCAAGCTCAACCAGA
AGCTGACATAA

Upstream 100 bases:

>100_bases
TCGCCGCGTCCGGCATCGAGGTACGCAAGCTGGAGCCGATTCAGCCCTCGATGGAGGACGTGTTCGTCGCTATGATCGAG
GCCGAGGAAAGGAAGGCCGC

Downstream 100 bases:

>100_bases
CGATATGTGGGAGCGAATCTCGGTCATCCTCCGCAAAGAGTTTCTGCAGGCGCTGCGTGAACCGCGCATGCGGGTGCTGC
TGTTCGTGCCGCCGGTGGTG

Product: ABC-2 type transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSYRRLKAICVKELHHITRDSRSLTMALAVPVMMLLLFGFALSLDVDRVPTMIHDQDQTAASRALVREFQGSRFFDVHMV
SDDAIIERAIDRSQTLMGVVIPRDYSQQLGAGRTAQVQILLDGSDSNTASIALGYAESLVRGYSLELRRGALNRRGGERL
APPVDARMRVWYNSSLESKNYVVPGLIAVILQIIAAMLTSLTIAREWEMGTMEQLLSTPLRPAELVLGKMMAYFAVGVAD
AAIAVLVGIVVFGVPFRGSYLLLAVSTCIFLFGALFWGIFVSAAAKSQLQAYQMGILSSFLPAFMLSGFIYSIETMPAPI
RFITRIVPARYVVTILKGLFLKGVGLSVLWQELMFLTLYALIMFLMATRKLNQKLT

Sequences:

>Translated_376_residues
MSYRRLKAICVKELHHITRDSRSLTMALAVPVMMLLLFGFALSLDVDRVPTMIHDQDQTAASRALVREFQGSRFFDVHMV
SDDAIIERAIDRSQTLMGVVIPRDYSQQLGAGRTAQVQILLDGSDSNTASIALGYAESLVRGYSLELRRGALNRRGGERL
APPVDARMRVWYNSSLESKNYVVPGLIAVILQIIAAMLTSLTIAREWEMGTMEQLLSTPLRPAELVLGKMMAYFAVGVAD
AAIAVLVGIVVFGVPFRGSYLLLAVSTCIFLFGALFWGIFVSAAAKSQLQAYQMGILSSFLPAFMLSGFIYSIETMPAPI
RFITRIVPARYVVTILKGLFLKGVGLSVLWQELMFLTLYALIMFLMATRKLNQKLT
>Mature_375_residues
SYRRLKAICVKELHHITRDSRSLTMALAVPVMMLLLFGFALSLDVDRVPTMIHDQDQTAASRALVREFQGSRFFDVHMVS
DDAIIERAIDRSQTLMGVVIPRDYSQQLGAGRTAQVQILLDGSDSNTASIALGYAESLVRGYSLELRRGALNRRGGERLA
PPVDARMRVWYNSSLESKNYVVPGLIAVILQIIAAMLTSLTIAREWEMGTMEQLLSTPLRPAELVLGKMMAYFAVGVADA
AIAVLVGIVVFGVPFRGSYLLLAVSTCIFLFGALFWGIFVSAAAKSQLQAYQMGILSSFLPAFMLSGFIYSIETMPAPIR
FITRIVPARYVVTILKGLFLKGVGLSVLWQELMFLTLYALIMFLMATRKLNQKLT

Specific function: Unknown

COG id: COG0842

COG function: function code V; ABC-type multidrug transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1787011, Length=345, Percent_Identity=37.3913043478261, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI1787010, Length=353, Percent_Identity=33.1444759206799, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI48994943, Length=370, Percent_Identity=27.8378378378378, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI226510979, Length=370, Percent_Identity=26.7567567567568, Blast_Score=108, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24650855, Length=375, Percent_Identity=22.1333333333333, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24650853, Length=375, Percent_Identity=22.1333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI85725260, Length=386, Percent_Identity=21.5025906735751, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000412
- InterPro:   IPR013525 [H]

Pfam domain/function: PF01061 ABC2_membrane [H]

EC number: NA

Molecular weight: Translated: 41636; Mature: 41505

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS51012 ABC_TM2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRRLKAICVKELHHITRDSRSLTMALAVPVMMLLLFGFALSLDVDRVPTMIHDQDQTA
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHCCCCHHH
ASRALVREFQGSRFFDVHMVSDDAIIERAIDRSQTLMGVVIPRDYSQQLGAGRTAQVQIL
HHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHEEEEECCCHHHHHCCCCCEEEEEE
LDGSDSNTASIALGYAESLVRGYSLELRRGALNRRGGERLAPPVDARMRVWYNSSLESKN
EECCCCCCCEEEHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCC
YVVPGLIAVILQIIAAMLTSLTIAREWEMGTMEQLLSTPLRPAELVLGKMMAYFAVGVAD
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AAIAVLVGIVVFGVPFRGSYLLLAVSTCIFLFGALFWGIFVSAAAKSQLQAYQMGILSSF
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPAFMLSGFIYSIETMPAPIRFITRIVPARYVVTILKGLFLKGVGLSVLWQELMFLTLYA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LIMFLMATRKLNQKLT
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SYRRLKAICVKELHHITRDSRSLTMALAVPVMMLLLFGFALSLDVDRVPTMIHDQDQTA
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHCCCCHHH
ASRALVREFQGSRFFDVHMVSDDAIIERAIDRSQTLMGVVIPRDYSQQLGAGRTAQVQIL
HHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHEEEEECCCHHHHHCCCCCEEEEEE
LDGSDSNTASIALGYAESLVRGYSLELRRGALNRRGGERLAPPVDARMRVWYNSSLESKN
EECCCCCCCEEEHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCC
YVVPGLIAVILQIIAAMLTSLTIAREWEMGTMEQLLSTPLRPAELVLGKMMAYFAVGVAD
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AAIAVLVGIVVFGVPFRGSYLLLAVSTCIFLFGALFWGIFVSAAAKSQLQAYQMGILSSF
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPAFMLSGFIYSIETMPAPIRFITRIVPARYVVTILKGLFLKGVGLSVLWQELMFLTLYA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LIMFLMATRKLNQKLT
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]