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The map label for this gene is macB [H]

Identifier: 116625052

GI number: 116625052

Start: 7506273

End: 7507547

Strand: Reverse

Name: macB [H]

Synonym: Acid_5982

Alternate gene names: 116625052

Gene position: 7507547-7506273 (Counterclockwise)

Preceding gene: 116625054

Following gene: 116625051

Centisome position: 75.33

GC content: 63.76

Gene sequence:

>1275_bases
ATGGCTCACAACGGCTCGGGGGCAGCCCGCTCCTGGCATAATTTCCAAAACGCGTTCCGCCTGGCGATGGATTCCATTCG
CGCCCATAAGCTGCGCAGTTTCCTGACTTTGCTGGGCGTAATCATCGGTGTTGCCAGCGTCATTATGGTGGGCGCTGCCA
TCGAAGGACTCGGCGTGTACGCCGAGCAGAGCACCGCCAAAGCCTTCGGCTCAGAATCCTTCATGGTCGCCCAAATCGCC
GCCACGGGCCGCCTCAGCCGCCGCGATCTCTTCGATAAACTGAAGCGCAACAAGCCGATCCGGACGGACGACGCACGCTT
CGTGGAAGCCCTCGCCGGCGACAAAGTCCTGTACAGCCCCTACCGGCAGCATATCTCCGACGTCAAGCGCGAGAACCTCA
CCTGCGAAGACAGTTCCATCCTCGGCGCCGCCTCGGCCATGGCCGGCATTCGCGATATCGGCGTCGTGGACGGGCGTTTC
TTTACCGAGCAGGAGGATCGCGCCCGCTCCTACGTCGCCGTCATCGGCGATACCGTGCGCACCACCCTTTTCCCCGGCGA
CGCTTCTCCGCTCAACCAGATCATCCGCATCGAAGGCATCGAGTTCACCGTGATCGGCGTGCAGGAGCGGCTCGGTTCCG
CGTTCGGCCGCGACCAGGACAACTCGGTTTACGTGCCCATCACCGCCTTTAACCGTATGTACGGACCGGGCACGGGTTTT
GCGCTCTTCGGCCGCCCCAAGCCGGGCAGCGGCCTCGACCTCACGGGAGCCCTCGACGAAACGCGCGTCGTCCTCCGCAC
CCGCTTCCATGCTCGCCCGGGTCAGCCCGATAATTTCGACGTGCTCACGCCGGACGCCATCCGCGGCTTCATCGACCAGG
TGCTCGGTATGATCGCCGCCATCGTAGTCCCCGTCACCTGCATCTCGCTCGTGGTGGGCGGTATCGTCATCATGAACATC
ATGCTGGTCTCCGTCACCGAGCGTACGCGCGAGATCGGCATCCGCAAAGCCATCGGCGCCCGCCATGGCGATGTCATGAT
GCAGATCCTCATCGAAGCCATGTTCCTCGCCAGCCTCGGGGGCGCCATGGGTGTCGCGGCCGGAGCGGCCGTTACCGCTT
TGCTAGGCCGCATCTTCGAAATTTCCATGCACATCACCATGGCTTACGTAGTGCTCTCGCTCGTCGTATCCAGCGTGGTC
GGAGTGGTCTCCGGCTGGTATCCCGCGTCGCGCGCGGCCAAGCTCGACCCGGTGGTGGCCCTGCGTGCGGAGTAA

Upstream 100 bases:

>100_bases
ATTGCGATCAAAGCAATCAGAAAAAGCGTCGTATAAGCCAGACGAAGTATCGGCATGACGGGGCGATCCTTCATCTTACG
TTATCCTGAAGGAAAGACAC

Downstream 100 bases:

>100_bases
CTCGTGAACATCAGCCCAACCCAGAACATGAAGATGGCCATTCAGGCCGTGGGCGCCCACCGCTTCCGCTCGCTGCTCAC
GGTACTCGGCATCGTCATCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MAHNGSGAARSWHNFQNAFRLAMDSIRAHKLRSFLTLLGVIIGVASVIMVGAAIEGLGVYAEQSTAKAFGSESFMVAQIA
ATGRLSRRDLFDKLKRNKPIRTDDARFVEALAGDKVLYSPYRQHISDVKRENLTCEDSSILGAASAMAGIRDIGVVDGRF
FTEQEDRARSYVAVIGDTVRTTLFPGDASPLNQIIRIEGIEFTVIGVQERLGSAFGRDQDNSVYVPITAFNRMYGPGTGF
ALFGRPKPGSGLDLTGALDETRVVLRTRFHARPGQPDNFDVLTPDAIRGFIDQVLGMIAAIVVPVTCISLVVGGIVIMNI
MLVSVTERTREIGIRKAIGARHGDVMMQILIEAMFLASLGGAMGVAAGAAVTALLGRIFEISMHITMAYVVLSLVVSSVV
GVVSGWYPASRAAKLDPVVALRAE

Sequences:

>Translated_424_residues
MAHNGSGAARSWHNFQNAFRLAMDSIRAHKLRSFLTLLGVIIGVASVIMVGAAIEGLGVYAEQSTAKAFGSESFMVAQIA
ATGRLSRRDLFDKLKRNKPIRTDDARFVEALAGDKVLYSPYRQHISDVKRENLTCEDSSILGAASAMAGIRDIGVVDGRF
FTEQEDRARSYVAVIGDTVRTTLFPGDASPLNQIIRIEGIEFTVIGVQERLGSAFGRDQDNSVYVPITAFNRMYGPGTGF
ALFGRPKPGSGLDLTGALDETRVVLRTRFHARPGQPDNFDVLTPDAIRGFIDQVLGMIAAIVVPVTCISLVVGGIVIMNI
MLVSVTERTREIGIRKAIGARHGDVMMQILIEAMFLASLGGAMGVAAGAAVTALLGRIFEISMHITMAYVVLSLVVSSVV
GVVSGWYPASRAAKLDPVVALRAE
>Mature_423_residues
AHNGSGAARSWHNFQNAFRLAMDSIRAHKLRSFLTLLGVIIGVASVIMVGAAIEGLGVYAEQSTAKAFGSESFMVAQIAA
TGRLSRRDLFDKLKRNKPIRTDDARFVEALAGDKVLYSPYRQHISDVKRENLTCEDSSILGAASAMAGIRDIGVVDGRFF
TEQEDRARSYVAVIGDTVRTTLFPGDASPLNQIIRIEGIEFTVIGVQERLGSAFGRDQDNSVYVPITAFNRMYGPGTGFA
LFGRPKPGSGLDLTGALDETRVVLRTRFHARPGQPDNFDVLTPDAIRGFIDQVLGMIAAIVVPVTCISLVVGGIVIMNIM
LVSVTERTREIGIRKAIGARHGDVMMQILIEAMFLASLGGAMGVAAGAAVTALLGRIFEISMHITMAYVVLSLVVSSVVG
VVSGWYPASRAAKLDPVVALRAE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=422, Percent_Identity=31.2796208530806, Blast_Score=151, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45516; Mature: 45385

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHNGSGAARSWHNFQNAFRLAMDSIRAHKLRSFLTLLGVIIGVASVIMVGAAIEGLGVY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AEQSTAKAFGSESFMVAQIAATGRLSRRDLFDKLKRNKPIRTDDARFVEALAGDKVLYSP
HHHHHHHHHCCCCEEEEEHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHH
YRQHISDVKRENLTCEDSSILGAASAMAGIRDIGVVDGRFFTEQEDRARSYVAVIGDTVR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHH
TTLFPGDASPLNQIIRIEGIEFTVIGVQERLGSAFGRDQDNSVYVPITAFNRMYGPGTGF
HEECCCCCHHHHHHHEECCCEEEEEEHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCE
ALFGRPKPGSGLDLTGALDETRVVLRTRFHARPGQPDNFDVLTPDAIRGFIDQVLGMIAA
EEECCCCCCCCCCEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IVVPVTCISLVVGGIVIMNIMLVSVTERTREIGIRKAIGARHGDVMMQILIEAMFLASLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
GAMGVAAGAAVTALLGRIFEISMHITMAYVVLSLVVSSVVGVVSGWYPASRAAKLDPVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
LRAE
EECC
>Mature Secondary Structure 
AHNGSGAARSWHNFQNAFRLAMDSIRAHKLRSFLTLLGVIIGVASVIMVGAAIEGLGVY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AEQSTAKAFGSESFMVAQIAATGRLSRRDLFDKLKRNKPIRTDDARFVEALAGDKVLYSP
HHHHHHHHHCCCCEEEEEHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHH
YRQHISDVKRENLTCEDSSILGAASAMAGIRDIGVVDGRFFTEQEDRARSYVAVIGDTVR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHH
TTLFPGDASPLNQIIRIEGIEFTVIGVQERLGSAFGRDQDNSVYVPITAFNRMYGPGTGF
HEECCCCCHHHHHHHEECCCEEEEEEHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCE
ALFGRPKPGSGLDLTGALDETRVVLRTRFHARPGQPDNFDVLTPDAIRGFIDQVLGMIAA
EEECCCCCCCCCCEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IVVPVTCISLVVGGIVIMNIMLVSVTERTREIGIRKAIGARHGDVMMQILIEAMFLASLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
GAMGVAAGAAVTALLGRIFEISMHITMAYVVLSLVVSSVVGVVSGWYPASRAAKLDPVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
LRAE
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA