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The map label for this gene is arsA1 [H]

Identifier: 116624985

GI number: 116624985

Start: 7412303

End: 7413490

Strand: Direct

Name: arsA1 [H]

Synonym: Acid_5915

Alternate gene names: 116624985

Gene position: 7412303-7413490 (Clockwise)

Preceding gene: 116624982

Following gene: 116624986

Centisome position: 74.38

GC content: 61.53

Gene sequence:

>1188_bases
ATGCGCATCCTTCTTTTCAGCGGCAAAGGAGGCGTCGGCAAAACCAGTCTGGCCGCGGCGACCGGCCTGGAGCTCTCCCG
CCGTGGCTACCGGACGCTGGTCATGAGCGTGGACCCCGCGCACAGCCTGGCGGACTCGTTTGACATGGAGACCACGCTCT
TCCATGGAAAGACCGGCGACCCCTTGAAGATCGACGAGAACCTGGCGATTCACGAGGTCAACATTCAAAAGGAAATCAAG
CGCCACTGGAGGGAGATTTCCTCCTACGTGATCAGCGTGCTGCGCACCACCGGGATCAGCGACGTGGAGGCCGAGGAACT
GGCCATACTGCCGGGTATGGAAGAGCTCAGCGCCATGATGTACGTGAACCAGTTCCGGCGCGAGAATCGCTACGACGTGA
TCGTGCTGGACTGCGCGCCGACCGCCGAATCGATGCGGTTTGTGAGCATGCCGACCACGCTCGAGTGGTACATGAAGCAC
ATTTTTCCGTTTCAGCGCGGCATCCTTAAAGCAGTGCGTCCGCTGGCCAACCGGGTCTCGCCCGTGGAACTGCCGCCGGA
CAGTTACTTCGGCAACATTCAGGACCTGTTCGGCCGCCTGGACGGGATCGGCGAACTGCTGGAGGATCCCAAGATCACCA
GCGTCCGGCTGGTGACCAATCCGGAGCGGATGGTGCTGCGCGAGACGCAGCGCGCCTTCGTATACTTCTCGCTGCACGGG
CTGACGGTGGACGGAATCATTGTCAATCGCGTTCTGCCGAGCCAGGTAACGGACGCGTTTTTCCAGGAATGGCGGGTTTC
GCAGGGGCACATACTGGAAGAAATCGACCGGTACTTTGCACCGGTCACGGTCAAGCGGGTGCCGCTGTTCACACATGAAG
TGCTGGGGCGCGAGCGGCTCGAAGACCTGGCGCGCTCGCTGTACGAAGGCAAGGAGGATCCGGCGGCCGTGGTCCGCACG
GAGGCGCCTTTCACGTTCGTCAAGACCGACGGCCACTACGAGGTGCGGCTGCAACTTCCATTCGCCGCCAAGGGCGAGAT
CGGCCTGTTCAAGAAGGGCGACGAGCTGGTGGTGGAAATCGGAACGCTGCGCCGGCATATCGGGCTTCCGACCTCGATGG
CCGCCCTTTCGCCCGGGCGCGCAAAGTTGGAGAATAAAGTATTGACTGTGGAAATGAAGGAGGCCTGA

Upstream 100 bases:

>100_bases
CGATACTGGGGATGCCGACGGCAAATTGAGGTTTCCAATCAAACATGCAGACCTTATCGGCTCCTCGAGCGCCGAGCTTT
AGGCGCGGTAATATCGAGAC

Downstream 100 bases:

>100_bases
GATGGACGAGAAAACCGCCGGAAGCGGAGCCGGACCGCACACTCACGATGGGCCCGGCTGCTTCTTTTGCAATACCGCCA
TGCCGGTGCTGGAACACATC

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase 1; Arsenite-translocating ATPase 1; Arsenite-transporting ATPase 1 [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MRILLFSGKGGVGKTSLAAATGLELSRRGYRTLVMSVDPAHSLADSFDMETTLFHGKTGDPLKIDENLAIHEVNIQKEIK
RHWREISSYVISVLRTTGISDVEAEELAILPGMEELSAMMYVNQFRRENRYDVIVLDCAPTAESMRFVSMPTTLEWYMKH
IFPFQRGILKAVRPLANRVSPVELPPDSYFGNIQDLFGRLDGIGELLEDPKITSVRLVTNPERMVLRETQRAFVYFSLHG
LTVDGIIVNRVLPSQVTDAFFQEWRVSQGHILEEIDRYFAPVTVKRVPLFTHEVLGRERLEDLARSLYEGKEDPAAVVRT
EAPFTFVKTDGHYEVRLQLPFAAKGEIGLFKKGDELVVEIGTLRRHIGLPTSMAALSPGRAKLENKVLTVEMKEA

Sequences:

>Translated_395_residues
MRILLFSGKGGVGKTSLAAATGLELSRRGYRTLVMSVDPAHSLADSFDMETTLFHGKTGDPLKIDENLAIHEVNIQKEIK
RHWREISSYVISVLRTTGISDVEAEELAILPGMEELSAMMYVNQFRRENRYDVIVLDCAPTAESMRFVSMPTTLEWYMKH
IFPFQRGILKAVRPLANRVSPVELPPDSYFGNIQDLFGRLDGIGELLEDPKITSVRLVTNPERMVLRETQRAFVYFSLHG
LTVDGIIVNRVLPSQVTDAFFQEWRVSQGHILEEIDRYFAPVTVKRVPLFTHEVLGRERLEDLARSLYEGKEDPAAVVRT
EAPFTFVKTDGHYEVRLQLPFAAKGEIGLFKKGDELVVEIGTLRRHIGLPTSMAALSPGRAKLENKVLTVEMKEA
>Mature_395_residues
MRILLFSGKGGVGKTSLAAATGLELSRRGYRTLVMSVDPAHSLADSFDMETTLFHGKTGDPLKIDENLAIHEVNIQKEIK
RHWREISSYVISVLRTTGISDVEAEELAILPGMEELSAMMYVNQFRRENRYDVIVLDCAPTAESMRFVSMPTTLEWYMKH
IFPFQRGILKAVRPLANRVSPVELPPDSYFGNIQDLFGRLDGIGELLEDPKITSVRLVTNPERMVLRETQRAFVYFSLHG
LTVDGIIVNRVLPSQVTDAFFQEWRVSQGHILEEIDRYFAPVTVKRVPLFTHEVLGRERLEDLARSLYEGKEDPAAVVRT
EAPFTFVKTDGHYEVRLQLPFAAKGEIGLFKKGDELVVEIGTLRRHIGLPTSMAALSPGRAKLENKVLTVEMKEA

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=302, Percent_Identity=21.8543046357616, Blast_Score=82, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320103, Length=326, Percent_Identity=24.2331288343558, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24586297, Length=313, Percent_Identity=22.6837060702875, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 44587; Mature: 44587

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLFSGKGGVGKTSLAAATGLELSRRGYRTLVMSVDPAHSLADSFDMETTLFHGKTGD
CEEEEEECCCCCCCHHHHHHHCCHHHCCCCEEEEEEECCHHHHHHHCCCCEEEEECCCCC
PLKIDENLAIHEVNIQKEIKRHWREISSYVISVLRTTGISDVEAEELAILPGMEELSAMM
CEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCHHHHHHHH
YVNQFRRENRYDVIVLDCAPTAESMRFVSMPTTLEWYMKHIFPFQRGILKAVRPLANRVS
HHHHHHHCCCCCEEEEECCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVELPPDSYFGNIQDLFGRLDGIGELLEDPKITSVRLVTNPERMVLRETQRAFVYFSLHG
CCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHCCEEEEEEEEEC
LTVDGIIVNRVLPSQVTDAFFQEWRVSQGHILEEIDRYFAPVTVKRVPLFTHEVLGRERL
EEECCEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHH
EDLARSLYEGKEDPAAVVRTEAPFTFVKTDGHYEVRLQLPFAAKGEIGLFKKGDELVVEI
HHHHHHHHCCCCCCCEEEEECCCEEEEEECCCEEEEEEECCCCCCCEEEEECCCCEEEEH
GTLRRHIGLPTSMAALSPGRAKLENKVLTVEMKEA
HHHHHHCCCCCHHHHCCCCHHHHCCCEEEEEECCC
>Mature Secondary Structure
MRILLFSGKGGVGKTSLAAATGLELSRRGYRTLVMSVDPAHSLADSFDMETTLFHGKTGD
CEEEEEECCCCCCCHHHHHHHCCHHHCCCCEEEEEEECCHHHHHHHCCCCEEEEECCCCC
PLKIDENLAIHEVNIQKEIKRHWREISSYVISVLRTTGISDVEAEELAILPGMEELSAMM
CEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCHHHHHHHH
YVNQFRRENRYDVIVLDCAPTAESMRFVSMPTTLEWYMKHIFPFQRGILKAVRPLANRVS
HHHHHHHCCCCCEEEEECCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVELPPDSYFGNIQDLFGRLDGIGELLEDPKITSVRLVTNPERMVLRETQRAFVYFSLHG
CCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHCCEEEEEEEEEC
LTVDGIIVNRVLPSQVTDAFFQEWRVSQGHILEEIDRYFAPVTVKRVPLFTHEVLGRERL
EEECCEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHH
EDLARSLYEGKEDPAAVVRTEAPFTFVKTDGHYEVRLQLPFAAKGEIGLFKKGDELVVEI
HHHHHHHHCCCCCCCEEEEECCCEEEEEECCCEEEEEEECCCCCCCEEEEECCCCEEEEH
GTLRRHIGLPTSMAALSPGRAKLENKVLTVEMKEA
HHHHHHCCCCCHHHHCCCCHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]