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The map label for this gene is atoS [C]

Identifier: 116624978

GI number: 116624978

Start: 7405359

End: 7407200

Strand: Reverse

Name: atoS [C]

Synonym: Acid_5908

Alternate gene names: 116624978

Gene position: 7407200-7405359 (Counterclockwise)

Preceding gene: 116624979

Following gene: 116624974

Centisome position: 74.33

GC content: 64.06

Gene sequence:

>1842_bases
ATGCTGCTGCGCCACGCTCTGGGCCCCTTCCTGGGCGGCCACTATCCCTTTCTGCTGCAGTTCTGCGCGATGCTCGCCGC
CGCGCGCTTCCTCGGTTTTGGTCCTGGCCTCGCCGCCCTGTTGACCGCCCTCTCGCCGAGCTTGTACGTTCTTGAAAAGC
ACTCGCAGCCCGAACTCCCGGTCGCCCGTCTTTTGGGATTCTCCGGCGCGGTTCTGTTCTGTCTCTTCCTCGTCTGGCTG
CTCGACCGGCAGGGTCGCATGCGCGTCGAAGTGCAGCGCAGCACCCGCCTCGCCGAGGAGCGGCTCGAAGTGCTGAGCAT
CGAGGTGGCTCAGCGCGAACGCGATCAGGAATTCGCCGCGCAGCTCCGCGACATCGTCGAATCCTCCGAAGACGCCATCA
TTTCGAAGGATATGAATGGCATCATACGCAGCTGGAACGATGGCGCCGAGCGGCTCTTCGGCTACTCGAAAGAGGAAACG
ATCGGGCAGCACATCACGCTCGTGGTGCCCGAGTCCCGCCGCCATGAGGAAGCCGGAATCCTCGCGCGCATCGGCGAGGG
CCTGCCGGTCAAACACTTCGAGACGGTTCGCTGCCGCAAAGACGGGCGCCTGATTCACGTATCGTTGACCATCTCACCCG
TGCGTGAAACCAGCGGCCGGATCGTCGGCGCCTCTCACATCGCGCGCGACATCACCGAGCGCATGGAGTTGGAGGAGCAA
CTTCGCCAGACTCAGAAACTGGAAAGCCTGGGCGTGCTTGCCGGGGGAATGGCGCATGACTTCAATAACCTGCTGACAGG
CGTTATGGGCAATGCCAGCCTGATCGCGGAGGAGCTAGGTCCCGAGAGCAGCGCCGCGCCGCGGCTGTCTGAAATTATGC
ACGCCAGCGAGCGCGCCGCACAACTGGTCCGGCAGATGCTCGCCTATGCCGGCAAGGGCCGGTTTGTCATGCAGCACCTG
GATATCTCTGAACAGATCGCCGGCATCGCGCCCTTGATTCGCACATCGATAACTCCCTCCGTGCAGCTTGAATTCAACCT
TGCCGAGAACTTGCCTGCCGTCGAGTGCGATGCCTCCCAGATTCAACAGTTGATCATGAACCTGGCCACCAACGCAGGCG
AGGCGATCGAGAGCCACGGGACCGTGACCATCACCACTTCCACTCACCGTACCGGCTCCGAGCGTCAGGTCGTCATCGAA
GTCAAAGACACCGGCTGCGGCATGGACGAAACCACCCGGGCGCGCATCTTCGACCCGTTCTTCACCACCAAATTCACCGG
CCGCGGGCTCGGCCTCGCCGCCGTCCTGGGAATCATTCGCAGCCACAACGGTTCGATCTCTGTGGAGAGCACGCCCGGCC
GCGGCAGTACTTTTACGGTCGCGCTTCCCGCCACCGCGCAGGATGTCGAGCCGGCGCAGCCCGATCCACACCTCGAACTG
CACGGGGCCGGCCACGTGCTCGTAGTGGACGATGAGGACCTGGTGCGCAACATGGCGCGCAGCGCACTCGAGCGCTGCGG
CTACACTGTGGAAGTGGCCGCCGACGGACTGCTCGCCGTGCAGGCTGTCACCGCCCGTCCCGCCCACTTCGATGCCGTCC
TGCTGGATCTCACCATGCCGGCGATGAATGGCGACGAGGCCCTGAAGGAGATCCACGCCATCCGCTCCGATATCCCGGTA
ATCCTCTCCAGCGGCTTCAGCGAAACCGAAGCCCTGCGCCGCTTCCAACACCGCGGCCTCGCCGGCTTCCTCCAAAAACC
CTACACGGCATCCGTCCTGGCCCGCAAGGTCAAACAGGCCATCGACCGTCCGCACCGCGCAAGCGCCCAGGCGAACGGCT
AG

Upstream 100 bases:

>100_bases
TGGTGCGTCGGGTATCATTGACTGACGGATGGATGTCAGCTTAAGAACGTATCCCGCGGCTGCGAGGTATACGGCTGCCG
TGGGTTTGAGCGGTGCGGCC

Downstream 100 bases:

>100_bases
TATTACACTGCTTTTGTTTGCTCGCAGGCCGCAAAGATTGGAGGGCCCCGCTTTGTGGGGCAGGCAATCCTGCCTGCAGC
CGCCTTTCAGGCGGCTTCCA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MLLRHALGPFLGGHYPFLLQFCAMLAAARFLGFGPGLAALLTALSPSLYVLEKHSQPELPVARLLGFSGAVLFCLFLVWL
LDRQGRMRVEVQRSTRLAEERLEVLSIEVAQRERDQEFAAQLRDIVESSEDAIISKDMNGIIRSWNDGAERLFGYSKEET
IGQHITLVVPESRRHEEAGILARIGEGLPVKHFETVRCRKDGRLIHVSLTISPVRETSGRIVGASHIARDITERMELEEQ
LRQTQKLESLGVLAGGMAHDFNNLLTGVMGNASLIAEELGPESSAAPRLSEIMHASERAAQLVRQMLAYAGKGRFVMQHL
DISEQIAGIAPLIRTSITPSVQLEFNLAENLPAVECDASQIQQLIMNLATNAGEAIESHGTVTITTSTHRTGSERQVVIE
VKDTGCGMDETTRARIFDPFFTTKFTGRGLGLAAVLGIIRSHNGSISVESTPGRGSTFTVALPATAQDVEPAQPDPHLEL
HGAGHVLVVDDEDLVRNMARSALERCGYTVEVAADGLLAVQAVTARPAHFDAVLLDLTMPAMNGDEALKEIHAIRSDIPV
ILSSGFSETEALRRFQHRGLAGFLQKPYTASVLARKVKQAIDRPHRASAQANG

Sequences:

>Translated_613_residues
MLLRHALGPFLGGHYPFLLQFCAMLAAARFLGFGPGLAALLTALSPSLYVLEKHSQPELPVARLLGFSGAVLFCLFLVWL
LDRQGRMRVEVQRSTRLAEERLEVLSIEVAQRERDQEFAAQLRDIVESSEDAIISKDMNGIIRSWNDGAERLFGYSKEET
IGQHITLVVPESRRHEEAGILARIGEGLPVKHFETVRCRKDGRLIHVSLTISPVRETSGRIVGASHIARDITERMELEEQ
LRQTQKLESLGVLAGGMAHDFNNLLTGVMGNASLIAEELGPESSAAPRLSEIMHASERAAQLVRQMLAYAGKGRFVMQHL
DISEQIAGIAPLIRTSITPSVQLEFNLAENLPAVECDASQIQQLIMNLATNAGEAIESHGTVTITTSTHRTGSERQVVIE
VKDTGCGMDETTRARIFDPFFTTKFTGRGLGLAAVLGIIRSHNGSISVESTPGRGSTFTVALPATAQDVEPAQPDPHLEL
HGAGHVLVVDDEDLVRNMARSALERCGYTVEVAADGLLAVQAVTARPAHFDAVLLDLTMPAMNGDEALKEIHAIRSDIPV
ILSSGFSETEALRRFQHRGLAGFLQKPYTASVLARKVKQAIDRPHRASAQANG
>Mature_613_residues
MLLRHALGPFLGGHYPFLLQFCAMLAAARFLGFGPGLAALLTALSPSLYVLEKHSQPELPVARLLGFSGAVLFCLFLVWL
LDRQGRMRVEVQRSTRLAEERLEVLSIEVAQRERDQEFAAQLRDIVESSEDAIISKDMNGIIRSWNDGAERLFGYSKEET
IGQHITLVVPESRRHEEAGILARIGEGLPVKHFETVRCRKDGRLIHVSLTISPVRETSGRIVGASHIARDITERMELEEQ
LRQTQKLESLGVLAGGMAHDFNNLLTGVMGNASLIAEELGPESSAAPRLSEIMHASERAAQLVRQMLAYAGKGRFVMQHL
DISEQIAGIAPLIRTSITPSVQLEFNLAENLPAVECDASQIQQLIMNLATNAGEAIESHGTVTITTSTHRTGSERQVVIE
VKDTGCGMDETTRARIFDPFFTTKFTGRGLGLAAVLGIIRSHNGSISVESTPGRGSTFTVALPATAQDVEPAQPDPHLEL
HGAGHVLVVDDEDLVRNMARSALERCGYTVEVAADGLLAVQAVTARPAHFDAVLLDLTMPAMNGDEALKEIHAIRSDIPV
ILSSGFSETEALRRFQHRGLAGFLQKPYTASVLARKVKQAIDRPHRASAQANG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=344, Percent_Identity=29.9418604651163, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=33.469387755102, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI48994928, Length=532, Percent_Identity=25.5639097744361, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788713, Length=406, Percent_Identity=24.384236453202, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081816, Length=365, Percent_Identity=26.3013698630137, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=27.6923076923077, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790300, Length=234, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=257, Percent_Identity=27.2373540856031, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789149, Length=217, Percent_Identity=24.8847926267281, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=33.0508474576271, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=174, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66797; Mature: 66797

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLRHALGPFLGGHYPFLLQFCAMLAAARFLGFGPGLAALLTALSPSLYVLEKHSQPELP
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCCCCCC
VARLLGFSGAVLFCLFLVWLLDRQGRMRVEVQRSTRLAEERLEVLSIEVAQRERDQEFAA
HHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLRDIVESSEDAIISKDMNGIIRSWNDGAERLFGYSKEETIGQHITLVVPESRRHEEAGI
HHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCHHHCCCEEEEEECCCCCCCCCCH
LARIGEGLPVKHFETVRCRKDGRLIHVSLTISPVRETSGRIVGASHIARDITERMELEEQ
HHHHCCCCCCCCHHHHEECCCCEEEEEEEEEEECHHCCCCEEEHHHHHHHHHHHHHHHHH
LRQTQKLESLGVLAGGMAHDFNNLLTGVMGNASLIAEELGPESSAAPRLSEIMHASERAA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
QLVRQMLAYAGKGRFVMQHLDISEQIAGIAPLIRTSITPSVQLEFNLAENLPAVECDASQ
HHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCHHH
IQQLIMNLATNAGEAIESHGTVTITTSTHRTGSERQVVIEVKDTGCGMDETTRARIFDPF
HHHHHHHHHCCCCHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHEECCH
FTTKFTGRGLGLAAVLGIIRSHNGSISVESTPGRGSTFTVALPATAQDVEPAQPDPHLEL
HHCEECCCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCEEE
HGAGHVLVVDDEDLVRNMARSALERCGYTVEVAADGLLAVQAVTARPAHFDAVLLDLTMP
ECCCEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCEEEEHHHHCCCCHHHEEEEEEECC
AMNGDEALKEIHAIRSDIPVILSSGFSETEALRRFQHRGLAGFLQKPYTASVLARKVKQA
CCCHHHHHHHHHHHHCCCCHHECCCCCHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHH
IDRPHRASAQANG
HCCCCCCCCCCCC
>Mature Secondary Structure
MLLRHALGPFLGGHYPFLLQFCAMLAAARFLGFGPGLAALLTALSPSLYVLEKHSQPELP
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCCCCCC
VARLLGFSGAVLFCLFLVWLLDRQGRMRVEVQRSTRLAEERLEVLSIEVAQRERDQEFAA
HHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLRDIVESSEDAIISKDMNGIIRSWNDGAERLFGYSKEETIGQHITLVVPESRRHEEAGI
HHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCHHHCCCEEEEEECCCCCCCCCCH
LARIGEGLPVKHFETVRCRKDGRLIHVSLTISPVRETSGRIVGASHIARDITERMELEEQ
HHHHCCCCCCCCHHHHEECCCCEEEEEEEEEEECHHCCCCEEEHHHHHHHHHHHHHHHHH
LRQTQKLESLGVLAGGMAHDFNNLLTGVMGNASLIAEELGPESSAAPRLSEIMHASERAA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
QLVRQMLAYAGKGRFVMQHLDISEQIAGIAPLIRTSITPSVQLEFNLAENLPAVECDASQ
HHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCHHH
IQQLIMNLATNAGEAIESHGTVTITTSTHRTGSERQVVIEVKDTGCGMDETTRARIFDPF
HHHHHHHHHCCCCHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHEECCH
FTTKFTGRGLGLAAVLGIIRSHNGSISVESTPGRGSTFTVALPATAQDVEPAQPDPHLEL
HHCEECCCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCEEE
HGAGHVLVVDDEDLVRNMARSALERCGYTVEVAADGLLAVQAVTARPAHFDAVLLDLTMP
ECCCEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCEEEEHHHHCCCCHHHEEEEEEECC
AMNGDEALKEIHAIRSDIPVILSSGFSETEALRRFQHRGLAGFLQKPYTASVLARKVKQA
CCCHHHHHHHHHHHHCCCCHHECCCCCHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHH
IDRPHRASAQANG
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA