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The map label for this gene is divK [H]

Identifier: 116624973

GI number: 116624973

Start: 7401461

End: 7402159

Strand: Direct

Name: divK [H]

Synonym: Acid_5903

Alternate gene names: 116624973

Gene position: 7401461-7402159 (Clockwise)

Preceding gene: 116624972

Following gene: 116624975

Centisome position: 74.27

GC content: 62.95

Gene sequence:

>699_bases
ATGGCCGGAGAGCCGATATTAATCGTCGACGACACGCCTGTGAACCTCAAATTGACCAGGATACTCCTGGTGAATGAAGG
GTATAAAGTGCTCACCGCGGCCAGCGCGGAAGAGGCACTGGAATTGTTGCGCGGATATCAGCCGCGCCTGGTTCTGGCCG
ATATCCAGCTCCCCGGAATCGACGGGCTGGAGATGACCCGGCGCATCAAGCAGGACGAGCGGACGCGGGATACCCTGGTG
GTCGCTCTCACAGCGTTCGCCATGAAGGGCGACGAACAACGTGCCATCGAGGCGGGCTGTGATGGCTACCTTGTCAAGCC
AATCGACACCCGCTCGTTCGGAGGCAAGATTCGGGAGCTCCTGGACAGCCGGCCCGCTCCACCGGTGACGGCCGGCCCCA
CGAGTGCCGAACGCGAGACCATGGCGATGGACGAGATGCAGACCCTGCAGCGCCGATTCCTGACCGAAGGCGAAGCGAGC
GCGCGCCGGATGCTGCTGGAGCTCGATGGCCCTTTTCAGGCCGCGGAAGCCGCGCGGACCGTGCATCAATGGATCGGAAC
CGGCGGTCTTCTGGGCTTCAGTGAAATCGCACGCCTGGCGCGCGAAGTCGAAACGCTGTTGCATGAACGGCCGGTGGATT
CGGCGCAGCTGCGTGAGACCTTGGGCGGGCTGGTCCTCGCCTTCAATTCCTCAGACTAA

Upstream 100 bases:

>100_bases
GCGTCTTCTCCGCATTGCTACCTTTGGATAGCGCACTTCGGATAACTTCGACCCAATAACTTTTCATGTTCGAAGGTACA
CTACGATACACTGACTTTGC

Downstream 100 bases:

>100_bases
AATCGCGGGCGGCCGGTCAAAACCGTGCGCCCGCGACTGGTAATGGTAGCTATAAGAATGAATACTTTATAGGCCCGACT
GTTCCTGGAAGACCAGCCTG

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MAGEPILIVDDTPVNLKLTRILLVNEGYKVLTAASAEEALELLRGYQPRLVLADIQLPGIDGLEMTRRIKQDERTRDTLV
VALTAFAMKGDEQRAIEAGCDGYLVKPIDTRSFGGKIRELLDSRPAPPVTAGPTSAERETMAMDEMQTLQRRFLTEGEAS
ARRMLLELDGPFQAAEAARTVHQWIGTGGLLGFSEIARLAREVETLLHERPVDSAQLRETLGGLVLAFNSSD

Sequences:

>Translated_232_residues
MAGEPILIVDDTPVNLKLTRILLVNEGYKVLTAASAEEALELLRGYQPRLVLADIQLPGIDGLEMTRRIKQDERTRDTLV
VALTAFAMKGDEQRAIEAGCDGYLVKPIDTRSFGGKIRELLDSRPAPPVTAGPTSAERETMAMDEMQTLQRRFLTEGEAS
ARRMLLELDGPFQAAEAARTVHQWIGTGGLLGFSEIARLAREVETLLHERPVDSAQLRETLGGLVLAFNSSD
>Mature_231_residues
AGEPILIVDDTPVNLKLTRILLVNEGYKVLTAASAEEALELLRGYQPRLVLADIQLPGIDGLEMTRRIKQDERTRDTLVV
ALTAFAMKGDEQRAIEAGCDGYLVKPIDTRSFGGKIRELLDSRPAPPVTAGPTSAERETMAMDEMQTLQRRFLTEGEASA
RRMLLELDGPFQAAEAARTVHQWIGTGGLLGFSEIARLAREVETLLHERPVDSAQLRETLGGLVLAFNSSD

Specific function: Essential protein that is involved in the control of cell division, probably through the regulation of ctrA. Its phosphorylation status is regulated by PdhS [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Note=Localized at one pole of the cell. Colocalizes with pdhS (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=103, Percent_Identity=37.8640776699029, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789149, Length=104, Percent_Identity=37.5, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1786599, Length=116, Percent_Identity=30.1724137931034, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788713, Length=206, Percent_Identity=26.6990291262136, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI48994928, Length=216, Percent_Identity=26.3888888888889, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 25456; Mature: 25324

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGEPILIVDDTPVNLKLTRILLVNEGYKVLTAASAEEALELLRGYQPRLVLADIQLPGI
CCCCCEEEECCCCCCEEEEEEEEEECCCEEEEECCHHHHHHHHHCCCCCEEEEEECCCCC
DGLEMTRRIKQDERTRDTLVVALTAFAMKGDEQRAIEAGCDGYLVKPIDTRSFGGKIREL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEECCCCCCHHHHHHHHH
LDSRPAPPVTAGPTSAERETMAMDEMQTLQRRFLTEGEASARRMLLELDGPFQAAEAART
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEECCCCHHHHHHHHH
VHQWIGTGGLLGFSEIARLAREVETLLHERPVDSAQLRETLGGLVLAFNSSD
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEECCC
>Mature Secondary Structure 
AGEPILIVDDTPVNLKLTRILLVNEGYKVLTAASAEEALELLRGYQPRLVLADIQLPGI
CCCCEEEECCCCCCEEEEEEEEEECCCEEEEECCHHHHHHHHHCCCCCEEEEEECCCCC
DGLEMTRRIKQDERTRDTLVVALTAFAMKGDEQRAIEAGCDGYLVKPIDTRSFGGKIREL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEECCCCCCHHHHHHHHH
LDSRPAPPVTAGPTSAERETMAMDEMQTLQRRFLTEGEASARRMLLELDGPFQAAEAART
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEECCCCHHHHHHHHH
VHQWIGTGGLLGFSEIARLAREVETLLHERPVDSAQLRETLGGLVLAFNSSD
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA