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The map label for this gene is solA [H]

Identifier: 116624968

GI number: 116624968

Start: 7392622

End: 7393749

Strand: Reverse

Name: solA [H]

Synonym: Acid_5898

Alternate gene names: 116624968

Gene position: 7393749-7392622 (Counterclockwise)

Preceding gene: 116624969

Following gene: 116624966

Centisome position: 74.19

GC content: 67.55

Gene sequence:

>1128_bases
ATGCGCTACGACGCGATCGTGATCGGGATCGGCGGCATGGGCAGCGCGGCGGCCTGGCATCTGGCGAGCAGGGGGCGGCG
CGTGCTGGGGCTGGAGCAGTTCACGATTCCGCACGAGATGGGGTCGTCGCACGGGGTGACGCGGATCATCCGGCTGGCGT
ATTCGGAGCATCCCTCGTACGTTCCGCTGCTGCGGCGGGCCTATGAGTTGTGGCGCGCGATGGAGCAGCGCGCGGGCGAG
CCGCTGCTGGTGATCACCGGCGGCGTGGATGTGGGGTGCGCCGACAGTGTGACGATCGAAGGCAGCCTGCGCAGCTGCCG
GGAACACGGACTGGCGCACGAGCTGCTGGACGCGGCGGAGGTCGGGAGGCGCTTTCCGGGCTTCCGGCTGCCGGGGGATT
TGGCGGCGGTGTATCAGCCCGAAGGCGGCATCGTGCTGCCGGAGAGGTCGATGGTGGTGCACGCGGCGGCGGCGCGGGAA
CTCGGCGCGGAGATCCACGAGGGCGAGCGGGTGATGGAGTGGCGGCCCGAGGGTGGCGGAGTCCGGGTGTGGACGGAGGC
CGGCGAGTATGCGGCGGACCGGCTGGTGATCACGGCGGGTCCGTGGGCGTCCCGATGCGTGCCGGAGTTGGAGCGGCTGG
CGATTCCAGAGCGGCAGGTGTTGATCTGGACGGCGCCGCGGCGGCCGGAACGCTTCGCGGTGGGCGCGTTCCCGATCTTC
AACATGGAGGCCGAGGAGGGTCGCTTCTATGGCTTCCCTGTATACGGCGTACCTGGGTTCAAGCTCGGGAAGTACCACCA
CCTGGGACAGCAGACAGACCCGGACCGGGTGGACCGCGAATTCCATCCGGAGGACGAGGCGGTGTTGCGCGCGGGAATCC
GGCGCTACTTTCCGGATGCGGACGGCGAGACGCTGCTGATGAAGACGTGCATGTTCACGAATTCTCCGGACGAGCATTTC
ATCCTGGATTTGCATCCGGAATGGCCACAGGTATCGATTGCGGCGGGGTTCTCCGGCCATGGCTTCAAATTCGCGCCGGT
GATCGGCGAGGTTATGGCGGACCTGGCGATGGAGGGCGGCTGTTCGCGGTTCGATTTGGGGTTGTTCGGGCTGCATCGTT
TCGTTTAG

Upstream 100 bases:

>100_bases
ATCACGGTCGAAAAGGACGGGCGGCAAAGCACTTCGCAGGTTGAGATCCGCAACGGCATCAATTACAGCAAGATCCCGCT
GGACCGGTGAAGCGACGGTG

Downstream 100 bases:

>100_bases
AGCGGCGTCAGAGGCGCAAGGCGAGGTTGACCGGGAGCGCGGCGGCGGGGCTGGGCGGTGTTGCAGGCGGAGCGTCAAAA
CGAACCCGATTCGGAGGGCC

Product: N-methyltryptophan oxidase

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MRYDAIVIGIGGMGSAAAWHLASRGRRVLGLEQFTIPHEMGSSHGVTRIIRLAYSEHPSYVPLLRRAYELWRAMEQRAGE
PLLVITGGVDVGCADSVTIEGSLRSCREHGLAHELLDAAEVGRRFPGFRLPGDLAAVYQPEGGIVLPERSMVVHAAAARE
LGAEIHEGERVMEWRPEGGGVRVWTEAGEYAADRLVITAGPWASRCVPELERLAIPERQVLIWTAPRRPERFAVGAFPIF
NMEAEEGRFYGFPVYGVPGFKLGKYHHLGQQTDPDRVDREFHPEDEAVLRAGIRRYFPDADGETLLMKTCMFTNSPDEHF
ILDLHPEWPQVSIAAGFSGHGFKFAPVIGEVMADLAMEGGCSRFDLGLFGLHRFV

Sequences:

>Translated_375_residues
MRYDAIVIGIGGMGSAAAWHLASRGRRVLGLEQFTIPHEMGSSHGVTRIIRLAYSEHPSYVPLLRRAYELWRAMEQRAGE
PLLVITGGVDVGCADSVTIEGSLRSCREHGLAHELLDAAEVGRRFPGFRLPGDLAAVYQPEGGIVLPERSMVVHAAAARE
LGAEIHEGERVMEWRPEGGGVRVWTEAGEYAADRLVITAGPWASRCVPELERLAIPERQVLIWTAPRRPERFAVGAFPIF
NMEAEEGRFYGFPVYGVPGFKLGKYHHLGQQTDPDRVDREFHPEDEAVLRAGIRRYFPDADGETLLMKTCMFTNSPDEHF
ILDLHPEWPQVSIAAGFSGHGFKFAPVIGEVMADLAMEGGCSRFDLGLFGLHRFV
>Mature_375_residues
MRYDAIVIGIGGMGSAAAWHLASRGRRVLGLEQFTIPHEMGSSHGVTRIIRLAYSEHPSYVPLLRRAYELWRAMEQRAGE
PLLVITGGVDVGCADSVTIEGSLRSCREHGLAHELLDAAEVGRRFPGFRLPGDLAAVYQPEGGIVLPERSMVVHAAAARE
LGAEIHEGERVMEWRPEGGGVRVWTEAGEYAADRLVITAGPWASRCVPELERLAIPERQVLIWTAPRRPERFAVGAFPIF
NMEAEEGRFYGFPVYGVPGFKLGKYHHLGQQTDPDRVDREFHPEDEAVLRAGIRRYFPDADGETLLMKTCMFTNSPDEHF
ILDLHPEWPQVSIAAGFSGHGFKFAPVIGEVMADLAMEGGCSRFDLGLFGLHRFV

Specific function: Catalyzes the oxidative demethylation of sarcosine [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI60499001, Length=380, Percent_Identity=36.5789473684211, Blast_Score=224, Evalue=9e-59,
Organism=Escherichia coli, GI1787298, Length=379, Percent_Identity=35.0923482849604, Blast_Score=190, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI115535191, Length=386, Percent_Identity=29.5336787564767, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25147318, Length=384, Percent_Identity=28.125, Blast_Score=158, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002204
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 41568; Mature: 41568

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYDAIVIGIGGMGSAAAWHLASRGRRVLGLEQFTIPHEMGSSHGVTRIIRLAYSEHPSY
CCCEEEEEEECCCCCHHHHHHHHCCCEEEEEHHCCCHHHCCCCCCHHHHHHHHHHCCCCH
VPLLRRAYELWRAMEQRAGEPLLVITGGVDVGCADSVTIEGSLRSCREHGLAHELLDAAE
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCHHHHHHHCCHHHHHHHHHH
VGRRFPGFRLPGDLAAVYQPEGGIVLPERSMVVHAAAARELGAEIHEGERVMEWRPEGGG
HHHCCCCCCCCCCEEEEEECCCCEECCCCCEEEEHHHHHHHHHHHHCCCEEEEEECCCCC
VRVWTEAGEYAADRLVITAGPWASRCVPELERLAIPERQVLIWTAPRRPERFAVGAFPIF
EEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCEEE
NMEAEEGRFYGFPVYGVPGFKLGKYHHLGQQTDPDRVDREFHPEDEAVLRAGIRRYFPDA
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCC
DGETLLMKTCMFTNSPDEHFILDLHPEWPQVSIAAGFSGHGFKFAPVIGEVMADLAMEGG
CCCEEEEEEHHHCCCCCCEEEEEECCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHCCC
CSRFDLGLFGLHRFV
CCEECHHHHHHHHCC
>Mature Secondary Structure
MRYDAIVIGIGGMGSAAAWHLASRGRRVLGLEQFTIPHEMGSSHGVTRIIRLAYSEHPSY
CCCEEEEEEECCCCCHHHHHHHHCCCEEEEEHHCCCHHHCCCCCCHHHHHHHHHHCCCCH
VPLLRRAYELWRAMEQRAGEPLLVITGGVDVGCADSVTIEGSLRSCREHGLAHELLDAAE
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCHHHHHHHCCHHHHHHHHHH
VGRRFPGFRLPGDLAAVYQPEGGIVLPERSMVVHAAAARELGAEIHEGERVMEWRPEGGG
HHHCCCCCCCCCCEEEEEECCCCEECCCCCEEEEHHHHHHHHHHHHCCCEEEEEECCCCC
VRVWTEAGEYAADRLVITAGPWASRCVPELERLAIPERQVLIWTAPRRPERFAVGAFPIF
EEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCEEE
NMEAEEGRFYGFPVYGVPGFKLGKYHHLGQQTDPDRVDREFHPEDEAVLRAGIRRYFPDA
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCC
DGETLLMKTCMFTNSPDEHFILDLHPEWPQVSIAAGFSGHGFKFAPVIGEVMADLAMEGG
CCCEEEEEEHHHCCCCCCEEEEEECCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHCCC
CSRFDLGLFGLHRFV
CCEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]