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The map label for this gene is motA [H]

Identifier: 116624959

GI number: 116624959

Start: 7381270

End: 7382145

Strand: Direct

Name: motA [H]

Synonym: Acid_5888

Alternate gene names: 116624959

Gene position: 7381270-7382145 (Clockwise)

Preceding gene: 116624957

Following gene: 116624960

Centisome position: 74.07

GC content: 60.27

Gene sequence:

>876_bases
ATGCTTTCAATCATCGGAATCGTAATCGTACTGGGCGCCATCGCTGCCGGCTACATGATGGAGCACGGAAAATTTCTGGT
TCTTTTGCAGCCGGCCGAATTAGTCATCATTTTTGGAGCGGCTATAGGGACGGTCGTCATCGCCAATCCCCTGCCGGTTC
TAACCAAAATTGCGAAGGGCCTGGTCGCCGTGTTCGCCGGCAGCCCGTTCACCAAGGCGCGCTATCTGGAGACTCTGAAA
ATGCTCTATGAGCTGTTCTCTCTCTCCCGCAAGGCCGGAACCGCGAAACTGGAAGAAGAAGTCGACAACCCGTCCAAGGG
ACAGGTCCTCAACAAATACCCGAAATTCCTGGCGCAGCACCATGCTCTCCACTTCCTCTGCGACACCCTGCGCATGGCCG
TCACCGGCGGCGTGGATCCACTGGAAATCGATTCCATGATGGAAGCCGATCTGGACGTGCACCACAAGGAATCCGCCGAA
CCCATCGCCGCCCTCAGCACCATGGCGGATGCCCTGCCCGGCCTCGGGATCGTCGCCGCCGTGCTCGGCGTCGTGCTCAC
CATGGGAGCCTTGGGCGGCCCCAAGGAAGCCATCGGTGAAAAGGTTGCCGCGGCCCTCGTCGGCACCTTTCTGGGCATCC
TTCTCTGCTACGGAATCTTCGGTCCGCTCGCCGTCGCAATGGGCAAGAACGCCGAAGCCGATTCCCAGTTCTACCTGGTG
CTGCGCATGGCGGCGCTCGGTTTCGTAAAGGAACTGAGCCCGATGCTCGCCGTGGAACTGGCTCGCCGCTCGATTCCCGC
GGTCGTCCGTCCTACTTTTCAGGAAATGGAAGCAGCCTGCCGCGGCGGCGGTAGCGTAGCTTCCAAGGCGGCTTAA

Upstream 100 bases:

>100_bases
TCTCGCCCACAACCTGCGCGACCACAAGGTAAGTCCCCGCTCCTCGCCGCTAAAGCGTTGACACTATTCCGTCGATAAGA
GCCTTGGTACAGACCGCCAC

Downstream 100 bases:

>100_bases
CCATGGCCCCTGAACCCGAGGCCCCGCCAAAACCGCCTGCACCGCCGCGCCCGATCTTTGTCATCAAGAAGAAGAAGGTC
ATGCACGGAGGCCACCACGG

Product: chemotaxis protein

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MLSIIGIVIVLGAIAAGYMMEHGKFLVLLQPAELVIIFGAAIGTVVIANPLPVLTKIAKGLVAVFAGSPFTKARYLETLK
MLYELFSLSRKAGTAKLEEEVDNPSKGQVLNKYPKFLAQHHALHFLCDTLRMAVTGGVDPLEIDSMMEADLDVHHKESAE
PIAALSTMADALPGLGIVAAVLGVVLTMGALGGPKEAIGEKVAAALVGTFLGILLCYGIFGPLAVAMGKNAEADSQFYLV
LRMAALGFVKELSPMLAVELARRSIPAVVRPTFQEMEAACRGGGSVASKAA

Sequences:

>Translated_291_residues
MLSIIGIVIVLGAIAAGYMMEHGKFLVLLQPAELVIIFGAAIGTVVIANPLPVLTKIAKGLVAVFAGSPFTKARYLETLK
MLYELFSLSRKAGTAKLEEEVDNPSKGQVLNKYPKFLAQHHALHFLCDTLRMAVTGGVDPLEIDSMMEADLDVHHKESAE
PIAALSTMADALPGLGIVAAVLGVVLTMGALGGPKEAIGEKVAAALVGTFLGILLCYGIFGPLAVAMGKNAEADSQFYLV
LRMAALGFVKELSPMLAVELARRSIPAVVRPTFQEMEAACRGGGSVASKAA
>Mature_291_residues
MLSIIGIVIVLGAIAAGYMMEHGKFLVLLQPAELVIIFGAAIGTVVIANPLPVLTKIAKGLVAVFAGSPFTKARYLETLK
MLYELFSLSRKAGTAKLEEEVDNPSKGQVLNKYPKFLAQHHALHFLCDTLRMAVTGGVDPLEIDSMMEADLDVHHKESAE
PIAALSTMADALPGLGIVAAVLGVVLTMGALGGPKEAIGEKVAAALVGTFLGILLCYGIFGPLAVAMGKNAEADSQFYLV
LRMAALGFVKELSPMLAVELARRSIPAVVRPTFQEMEAACRGGGSVASKAA

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=281, Percent_Identity=37.0106761565836, Blast_Score=204, Evalue=6e-54,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30515; Mature: 30515

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIIGIVIVLGAIAAGYMMEHGKFLVLLQPAELVIIFGAAIGTVVIANPLPVLTKIAKG
CHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEHHHHHHHHHHCCCHHHHHHHHHH
LVAVFAGSPFTKARYLETLKMLYELFSLSRKAGTAKLEEEVDNPSKGQVLNKYPKFLAQH
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHH
HALHFLCDTLRMAVTGGVDPLEIDSMMEADLDVHHKESAEPIAALSTMADALPGLGIVAA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
VLGVVLTMGALGGPKEAIGEKVAAALVGTFLGILLCYGIFGPLAVAMGKNAEADSQFYLV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LRMAALGFVKELSPMLAVELARRSIPAVVRPTFQEMEAACRGGGSVASKAA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MLSIIGIVIVLGAIAAGYMMEHGKFLVLLQPAELVIIFGAAIGTVVIANPLPVLTKIAKG
CHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEHHHHHHHHHHCCCHHHHHHHHHH
LVAVFAGSPFTKARYLETLKMLYELFSLSRKAGTAKLEEEVDNPSKGQVLNKYPKFLAQH
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHH
HALHFLCDTLRMAVTGGVDPLEIDSMMEADLDVHHKESAEPIAALSTMADALPGLGIVAA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
VLGVVLTMGALGGPKEAIGEKVAAALVGTFLGILLCYGIFGPLAVAMGKNAEADSQFYLV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LRMAALGFVKELSPMLAVELARRSIPAVVRPTFQEMEAACRGGGSVASKAA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]