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The map label for this gene is yoaE [H]

Identifier: 116624930

GI number: 116624930

Start: 7334908

End: 7336956

Strand: Direct

Name: yoaE [H]

Synonym: Acid_5857

Alternate gene names: 116624930

Gene position: 7334908-7336956 (Clockwise)

Preceding gene: 116624928

Following gene: 116624931

Centisome position: 73.6

GC content: 65.89

Gene sequence:

>2049_bases
ATGGCCGAAACCCGTCACTCCGTGTGTGCCTTGGATTGCCCGGACTGCTGCTCGCTCCTAATCAACGTGGAGGATGGGCG
CGGCTCGAAGCTGCGCGGGAATCCCGAACATCCGGTGACGCGCGGCTTCCTGTGCGGCAAAGTGGCGCAATACCTGGAGC
GCGAATATCATCCCGACCGGCTGCTCTATCCGCAGAGGCGTGGGGGCGCGAAGGGCGCGGGACGGTTCGAGCGGATCACG
TGGGACCAGGCGTTGGACACGATTGCGGAGCGCCTGCGCTCGGTGGCAACGGAGTTCGGCTCCGAGGCCATCCTACCCTA
CAGCTACGCGGGCACAATGGGGCTCCTCAATGGCAGCGGCATGGACCGGCGCTTCTTCCACCGCCTGGGAGCGTCGCGGC
TGGACCGCACCATCTGCTCGTCCGCCGGCGGAGTCGGGCTCACACAGGCGCTGGGCCTGCGCTATGGCACGGAGCCCGAG
CAGTTCCGCCACGCGAAGCTGATCATTGCCTGGGGCGCGAACATTCTCGGCACCAACGTTCACCTCTGGCCGTTCGTGAT
GGAAGCGCGGCGCAATGGGGCGAAGCTGTACACCATAGACCCGAATCGCAACCGCACGGGAGCGGCCAGCGACAAGCATT
TCTTCATCAATCCGGGGAGCGACACGGCGCTGGCGCTCGCCATGATGCACGTGATCCTCGGCGAAGGGCTGCACGATCCC
GACTACGTGGAGCGCCACACCAGCGGAATCGACGCGCTGCGCGAACGGGTGCTGGCGTGGACGCCGGCGCGCGCCGCGGA
ATTGACCGGGATCGCGGCCGAAGAGATTGTGCAATTGGCGCGCGAGTACGCGGGCACGCGTCCGGCAGCCATCCGGCTCA
ATTACGGGGTACAGCGCAGCGAGCGCGGCGCCACCGCGATCCGCACTATTGCGCTGTTGCCGGCGCTGACCGGGAGTTGG
AAGGATGTGGGCGGCGGGTTACAACTCTCCACGTCGCAGGCGTTCTATCTGAATCGCGCCGGATTGGAGCGAGCCGACCT
GCAGCATCGCTCGCTGGGCCGGGAGGCGCGCATCGTCAACATGTCGCAATTAGGGCAGGCGCTAACCGAGTTGGCCGATC
CGCCGGTGAAGGCGATGATCGTCTACAACTCCAACCCGGGAGCGATTGCGCCCAACCAGAATGCCGTGCAGCGCGGCCTG
CGGCGCGAGGATCTCTTCACCGTGGTGCTGGAGCAGTTTCAGACTGACACCGCGGATCACGCCGATATCCTGCTTCCCGT
GACCACGTTCCTGGAGCACACGGACCTTTACCTGGCGTACGGCCACTACCACTTGCAGCTGGCGCGGCCCGCTCTGCCGG
CTCCGGGCGAAACCAAAAGCAACGTGGAGATCTTCCGGCTGCTGGCGCAGCGCATGGGGTTCGAGGATCCGTGCTTCAGG
GAATCCGAAGACGACATGATTCGCACGCTGCTGGATTCGCCGCACCCGTTCCTGGCGGGAATCACGCTGGAGCAACTCGA
CCGCGAGCACTCCGTGCGGCTCAAGGTCTCCGGGGATGGCGAGCCCTTCCTGCCGTTCGCCGAGGGCAACTTCGGCACGC
CTGATGGCCGATGCCACTTCAACGCGGAGACGCTGGATTACACACCGCCGGTGGAATCGCGCCACGGCGACGCGGTGTTG
CGGAGCAAGTATCCGCTCGAGTTGATTTCGCCGAAGAATGACGACAGCATGAACTCCACCTTCGGCCATCGCGATGGCGT
GGACCGGCAGACCGCGACCCTGTACCTGGCCGGACCCGACGCCGCCGCGCGCGGAATCCGCGATGCCGACCAGGTGCGCG
TCTATAACGACCGCGGCTCCTGCGTGCTCTCGGCGAGCGTGGATGGACGCGTCCGCCCGGGAGTGGCGTGCGCGCCGGCG
GTGCGCTGGGGCAAGCGTTCGCCGGGCGGAAACAGCATCAACGCCGTCACCAGTGAGCGGCTCACGGATTTCGGCGGCGG
CGCTACTTTTTACAGCTGCCTCGTTCAAGTTGAGAGAATCGGAGACTGA

Upstream 100 bases:

>100_bases
GGACCCAGAAGATCGCCGACAGCAATGGGCATGGCCGTGACTGATTCTACCCTACGCCGGGGCGTCCGGCCCTCGAACCC
CACGATATAATTGGGGGGCA

Downstream 100 bases:

>100_bases
TGCGATACACATTGCTTTCCCGACGGCGCGCCGTGGCGCGCATGCTCGGCACGGTAGCGCTCGTGGCGCTGGTACTGGCG
CCCGTGGCCTGCAAGAACAA

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 681

Protein sequence:

>682_residues
MAETRHSVCALDCPDCCSLLINVEDGRGSKLRGNPEHPVTRGFLCGKVAQYLEREYHPDRLLYPQRRGGAKGAGRFERIT
WDQALDTIAERLRSVATEFGSEAILPYSYAGTMGLLNGSGMDRRFFHRLGASRLDRTICSSAGGVGLTQALGLRYGTEPE
QFRHAKLIIAWGANILGTNVHLWPFVMEARRNGAKLYTIDPNRNRTGAASDKHFFINPGSDTALALAMMHVILGEGLHDP
DYVERHTSGIDALRERVLAWTPARAAELTGIAAEEIVQLAREYAGTRPAAIRLNYGVQRSERGATAIRTIALLPALTGSW
KDVGGGLQLSTSQAFYLNRAGLERADLQHRSLGREARIVNMSQLGQALTELADPPVKAMIVYNSNPGAIAPNQNAVQRGL
RREDLFTVVLEQFQTDTADHADILLPVTTFLEHTDLYLAYGHYHLQLARPALPAPGETKSNVEIFRLLAQRMGFEDPCFR
ESEDDMIRTLLDSPHPFLAGITLEQLDREHSVRLKVSGDGEPFLPFAEGNFGTPDGRCHFNAETLDYTPPVESRHGDAVL
RSKYPLELISPKNDDSMNSTFGHRDGVDRQTATLYLAGPDAAARGIRDADQVRVYNDRGSCVLSASVDGRVRPGVACAPA
VRWGKRSPGGNSINAVTSERLTDFGGGATFYSCLVQVERIGD

Sequences:

>Translated_682_residues
MAETRHSVCALDCPDCCSLLINVEDGRGSKLRGNPEHPVTRGFLCGKVAQYLEREYHPDRLLYPQRRGGAKGAGRFERIT
WDQALDTIAERLRSVATEFGSEAILPYSYAGTMGLLNGSGMDRRFFHRLGASRLDRTICSSAGGVGLTQALGLRYGTEPE
QFRHAKLIIAWGANILGTNVHLWPFVMEARRNGAKLYTIDPNRNRTGAASDKHFFINPGSDTALALAMMHVILGEGLHDP
DYVERHTSGIDALRERVLAWTPARAAELTGIAAEEIVQLAREYAGTRPAAIRLNYGVQRSERGATAIRTIALLPALTGSW
KDVGGGLQLSTSQAFYLNRAGLERADLQHRSLGREARIVNMSQLGQALTELADPPVKAMIVYNSNPGAIAPNQNAVQRGL
RREDLFTVVLEQFQTDTADHADILLPVTTFLEHTDLYLAYGHYHLQLARPALPAPGETKSNVEIFRLLAQRMGFEDPCFR
ESEDDMIRTLLDSPHPFLAGITLEQLDREHSVRLKVSGDGEPFLPFAEGNFGTPDGRCHFNAETLDYTPPVESRHGDAVL
RSKYPLELISPKNDDSMNSTFGHRDGVDRQTATLYLAGPDAAARGIRDADQVRVYNDRGSCVLSASVDGRVRPGVACAPA
VRWGKRSPGGNSINAVTSERLTDFGGGATFYSCLVQVERIGD
>Mature_681_residues
AETRHSVCALDCPDCCSLLINVEDGRGSKLRGNPEHPVTRGFLCGKVAQYLEREYHPDRLLYPQRRGGAKGAGRFERITW
DQALDTIAERLRSVATEFGSEAILPYSYAGTMGLLNGSGMDRRFFHRLGASRLDRTICSSAGGVGLTQALGLRYGTEPEQ
FRHAKLIIAWGANILGTNVHLWPFVMEARRNGAKLYTIDPNRNRTGAASDKHFFINPGSDTALALAMMHVILGEGLHDPD
YVERHTSGIDALRERVLAWTPARAAELTGIAAEEIVQLAREYAGTRPAAIRLNYGVQRSERGATAIRTIALLPALTGSWK
DVGGGLQLSTSQAFYLNRAGLERADLQHRSLGREARIVNMSQLGQALTELADPPVKAMIVYNSNPGAIAPNQNAVQRGLR
REDLFTVVLEQFQTDTADHADILLPVTTFLEHTDLYLAYGHYHLQLARPALPAPGETKSNVEIFRLLAQRMGFEDPCFRE
SEDDMIRTLLDSPHPFLAGITLEQLDREHSVRLKVSGDGEPFLPFAEGNFGTPDGRCHFNAETLDYTPPVESRHGDAVLR
SKYPLELISPKNDDSMNSTFGHRDGVDRQTATLYLAGPDAAARGIRDADQVRVYNDRGSCVLSASVDGRVRPGVACAPAV
RWGKRSPGGNSINAVTSERLTDFGGGATFYSCLVQVERIGD

Specific function: Terminal Reductase During Anaerobic Growth On Various Sulfoxide And N-Oxide Compounds (By Similarity). [C]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI171474008, Length=773, Percent_Identity=28.2018111254851, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI87081797, Length=770, Percent_Identity=26.7532467532467, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1787870, Length=765, Percent_Identity=25.8823529411765, Blast_Score=185, Evalue=8e-48,
Organism=Escherichia coli, GI3868721, Length=718, Percent_Identity=25.3481894150418, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1787231, Length=663, Percent_Identity=25.9426847662142, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI145693196, Length=687, Percent_Identity=24.5997088791849, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87081994, Length=685, Percent_Identity=23.2116788321168, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1788534, Length=804, Percent_Identity=21.1442786069652, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI3868720, Length=274, Percent_Identity=26.6423357664234, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI3868719, Length=440, Percent_Identity=22.2727272727273, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 74815; Mature: 74684

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETRHSVCALDCPDCCSLLINVEDGRGSKLRGNPEHPVTRGFLCGKVAQYLEREYHPDR
CCCCCCCEEECCCHHHEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
LLYPQRRGGAKGAGRFERITWDQALDTIAERLRSVATEFGSEAILPYSYAGTMGLLNGSG
CCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCC
MDRRFFHRLGASRLDRTICSSAGGVGLTQALGLRYGTEPEQFRHAKLIIAWGANILGTNV
CCHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHEEEEEEEECCHHHCCCE
HLWPFVMEARRNGAKLYTIDPNRNRTGAASDKHFFINPGSDTALALAMMHVILGEGLHDP
EHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCH
DYVERHTSGIDALRERVLAWTPARAAELTGIAAEEIVQLAREYAGTRPAAIRLNYGVQRS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCC
ERGATAIRTIALLPALTGSWKDVGGGLQLSTSQAFYLNRAGLERADLQHRSLGREARIVN
CCCHHHHHHHHHHHHHCCCCHHCCCCEEEECCCEEEEECCCCCHHHHHHHHCCCCCEEEC
MSQLGQALTELADPPVKAMIVYNSNPGAIAPNQNAVQRGLRREDLFTVVLEQFQTDTADH
HHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCC
ADILLPVTTFLEHTDLYLAYGHYHLQLARPALPAPGETKSNVEIFRLLAQRMGFEDPCFR
CCEEEHHHHHHHHCCEEEEECEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
ESEDDMIRTLLDSPHPFLAGITLEQLDREHSVRLKVSGDGEPFLPFAEGNFGTPDGRCHF
CCHHHHHHHHHCCCCCCEECCCHHHCCCCCCEEEEECCCCCCCCEECCCCCCCCCCEEEE
NAETLDYTPPVESRHGDAVLRSKYPLELISPKNDDSMNSTFGHRDGVDRQTATLYLAGPD
CCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
AAARGIRDADQVRVYNDRGSCVLSASVDGRVRPGVACAPAVRWGKRSPGGNSINAVTSER
HHHHCCCCCCCEEEECCCCCEEEEECCCCCCCCCCEECHHHHCCCCCCCCCCCHHHHHHH
LTDFGGGATFYSCLVQVERIGD
HHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AETRHSVCALDCPDCCSLLINVEDGRGSKLRGNPEHPVTRGFLCGKVAQYLEREYHPDR
CCCCCCEEECCCHHHEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
LLYPQRRGGAKGAGRFERITWDQALDTIAERLRSVATEFGSEAILPYSYAGTMGLLNGSG
CCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCC
MDRRFFHRLGASRLDRTICSSAGGVGLTQALGLRYGTEPEQFRHAKLIIAWGANILGTNV
CCHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHEEEEEEEECCHHHCCCE
HLWPFVMEARRNGAKLYTIDPNRNRTGAASDKHFFINPGSDTALALAMMHVILGEGLHDP
EHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCH
DYVERHTSGIDALRERVLAWTPARAAELTGIAAEEIVQLAREYAGTRPAAIRLNYGVQRS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCC
ERGATAIRTIALLPALTGSWKDVGGGLQLSTSQAFYLNRAGLERADLQHRSLGREARIVN
CCCHHHHHHHHHHHHHCCCCHHCCCCEEEECCCEEEEECCCCCHHHHHHHHCCCCCEEEC
MSQLGQALTELADPPVKAMIVYNSNPGAIAPNQNAVQRGLRREDLFTVVLEQFQTDTADH
HHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCC
ADILLPVTTFLEHTDLYLAYGHYHLQLARPALPAPGETKSNVEIFRLLAQRMGFEDPCFR
CCEEEHHHHHHHHCCEEEEECEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
ESEDDMIRTLLDSPHPFLAGITLEQLDREHSVRLKVSGDGEPFLPFAEGNFGTPDGRCHF
CCHHHHHHHHHCCCCCCEECCCHHHCCCCCCEEEEECCCCCCCCEECCCCCCCCCCEEEE
NAETLDYTPPVESRHGDAVLRSKYPLELISPKNDDSMNSTFGHRDGVDRQTATLYLAGPD
CCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
AAARGIRDADQVRVYNDRGSCVLSASVDGRVRPGVACAPAVRWGKRSPGGNSINAVTSER
HHHHCCCCCCCEEEECCCCCEEEEECCCCCCCCCCEECHHHHCCCCCCCCCCCHHHHHHH
LTDFGGGATFYSCLVQVERIGD
HHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: Fe; Mo [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]