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The map label for this gene is arcD [H]

Identifier: 116624872

GI number: 116624872

Start: 7261184

End: 7262614

Strand: Reverse

Name: arcD [H]

Synonym: Acid_5796

Alternate gene names: 116624872

Gene position: 7262614-7261184 (Counterclockwise)

Preceding gene: 116624873

Following gene: 116624871

Centisome position: 72.88

GC content: 58.84

Gene sequence:

>1431_bases
ATGACCACATCAGCGACCCAGAAGTTCTCCCTACCGGTATTGACCGCCATGGTCGTGGGCTCTATGGTGGGCGCCGGTAT
CTTTTCGCTGCCCCAAACCTTTGGCAGGGTGACCGGTGTATACGGCGCCCTGGTGGCCTGGATTATCGCTGGCGTAGGCA
TGTTGATGCTGGCCTTGGTATTCCAGACTTTGGCACAACGCAAGCCTGATCTGGACGCCGGCGTTTATGCCTATGCGAAG
GCCGGCTTCGGGAATTACTGGGGCTTCCTCTCGGCGCTCGGTTACTGGGCGGGGAGTTGCATCGGCAACGTATCTTACTT
TGTGCTGATCAAGTCAACCCTGGGCGCGTTCTTCCCAGTATTCGGCGATGGCAATACCATTCAGGCTGTCCTGGTTTCGT
CGGTCATCTTGTGGACCTTCCATTTCATGATTCTGCGCGGCATCAAACAGGCTGCGGTGTTGAACACGATTGCGACCGTC
GCCAAGCTCATACCGATCCTGATCTTCATCGTCATCCTGGCGTTCAACTTCAACGCGGACATCTTCCGCGATAACCTTTG
GGGCGGCGCGGGGGCAGAACTCGGCGGCCTTTTCAGCCAGGTCCGCGGGACGATGCTGGTAACCGTATTCGTGTTTCTGG
GAATCGAAGGCGCCAGCGTCTATTCGCGCTACGCCAAGAAGCGGAGCGATGTCGGCGTGGCCACGGTGATGGGATTTCTC
GGCGTGCTCTGCATCCTGGTCCTGGTCACGATGCTCTCGTACGGCGTGCTGCCGCGGGCGGACCTGGCGGGGCTGCGGAA
TCCGTCGATGGCGGGCGTGTTGGAGTCCGTGGTGGGCCGCTGGGGAGCGATCTTTGTGAGCGCCGGCCTGATTATTTCCG
TGTTGGGCGCGTACCTTTCGTGGACGCTGCTGTGCGCGGAGGTTTTGTTCTCAGCCGCGGAAAACGAGACCATGCCCACC
ATGCTTGCCCACCAGAACGCGAACTCGGTGCCCTCGGCGGCTCTGTGGCTGACCAACAGTGTGGTGCAGCTCTTTCTTAT
CCTTACCTTGTTTGCGCAATATGCTTTTACCCTTGCCCTGGAACTTACCAGCTCCATGACCCTCATTCCGTTCTTCCTGG
TTGCGGCATATGCGGTTCAACTGGCCTGGAAAGGCGAGACGTATGAAGCAGAACCCGACCGGCGCCGGCGGGATCTGACC
CTCGCCAGCCTCGCACTGTTCTATACGGCCTGGCTACTATTGGCGGCGGGATTGAAATTCCTTCTGCTATCCGCCGTGAT
CTACGGTCCCGGCACGGTGCTGTTCTTCCTAGCGCGCCGCGAGCAAAACACCTATGTATTCACACCCAGGGAGCGAATCG
CGTTTGCCGCCGCTGTTATAGCCGCGATTGTCGCCATCATCAAGCTGGCGTCCGGTTCCATTTCTATTTAG

Upstream 100 bases:

>100_bases
GGAGGGCCGCGAATTCCAGCGGCAATCGGAGCACGGCTAACTTACAGCACCGAGACGGAGTGGTTGAGACGTTCGACCGT
TTTTGACGAGGGGTATCACA

Downstream 100 bases:

>100_bases
GAGAGTTATCATGTCGAACGTTATGACCGAGCATCCGGTCGAAAAGAAGTCCAAGGCCGAACACGCTGTCCGATACGGCG
TCTATTCCGAGGTTGGCAAG

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MTTSATQKFSLPVLTAMVVGSMVGAGIFSLPQTFGRVTGVYGALVAWIIAGVGMLMLALVFQTLAQRKPDLDAGVYAYAK
AGFGNYWGFLSALGYWAGSCIGNVSYFVLIKSTLGAFFPVFGDGNTIQAVLVSSVILWTFHFMILRGIKQAAVLNTIATV
AKLIPILIFIVILAFNFNADIFRDNLWGGAGAELGGLFSQVRGTMLVTVFVFLGIEGASVYSRYAKKRSDVGVATVMGFL
GVLCILVLVTMLSYGVLPRADLAGLRNPSMAGVLESVVGRWGAIFVSAGLIISVLGAYLSWTLLCAEVLFSAAENETMPT
MLAHQNANSVPSAALWLTNSVVQLFLILTLFAQYAFTLALELTSSMTLIPFFLVAAYAVQLAWKGETYEAEPDRRRRDLT
LASLALFYTAWLLLAAGLKFLLLSAVIYGPGTVLFFLARREQNTYVFTPRERIAFAAAVIAAIVAIIKLASGSISI

Sequences:

>Translated_476_residues
MTTSATQKFSLPVLTAMVVGSMVGAGIFSLPQTFGRVTGVYGALVAWIIAGVGMLMLALVFQTLAQRKPDLDAGVYAYAK
AGFGNYWGFLSALGYWAGSCIGNVSYFVLIKSTLGAFFPVFGDGNTIQAVLVSSVILWTFHFMILRGIKQAAVLNTIATV
AKLIPILIFIVILAFNFNADIFRDNLWGGAGAELGGLFSQVRGTMLVTVFVFLGIEGASVYSRYAKKRSDVGVATVMGFL
GVLCILVLVTMLSYGVLPRADLAGLRNPSMAGVLESVVGRWGAIFVSAGLIISVLGAYLSWTLLCAEVLFSAAENETMPT
MLAHQNANSVPSAALWLTNSVVQLFLILTLFAQYAFTLALELTSSMTLIPFFLVAAYAVQLAWKGETYEAEPDRRRRDLT
LASLALFYTAWLLLAAGLKFLLLSAVIYGPGTVLFFLARREQNTYVFTPRERIAFAAAVIAAIVAIIKLASGSISI
>Mature_475_residues
TTSATQKFSLPVLTAMVVGSMVGAGIFSLPQTFGRVTGVYGALVAWIIAGVGMLMLALVFQTLAQRKPDLDAGVYAYAKA
GFGNYWGFLSALGYWAGSCIGNVSYFVLIKSTLGAFFPVFGDGNTIQAVLVSSVILWTFHFMILRGIKQAAVLNTIATVA
KLIPILIFIVILAFNFNADIFRDNLWGGAGAELGGLFSQVRGTMLVTVFVFLGIEGASVYSRYAKKRSDVGVATVMGFLG
VLCILVLVTMLSYGVLPRADLAGLRNPSMAGVLESVVGRWGAIFVSAGLIISVLGAYLSWTLLCAEVLFSAAENETMPTM
LAHQNANSVPSAALWLTNSVVQLFLILTLFAQYAFTLALELTSSMTLIPFFLVAAYAVQLAWKGETYEAEPDRRRRDLTL
ASLALFYTAWLLLAAGLKFLLLSAVIYGPGTVLFFLARREQNTYVFTPRERIAFAAAVIAAIVAIIKLASGSISI

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=466, Percent_Identity=42.274678111588, Blast_Score=350, Evalue=8e-98,
Organism=Escherichia coli, GI2367353, Length=444, Percent_Identity=28.1531531531532, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1790575, Length=377, Percent_Identity=27.0557029177719, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786908, Length=437, Percent_Identity=22.4256292906178, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51083; Mature: 50952

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCHHHHHHEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTSATQKFSLPVLTAMVVGSMVGAGIFSLPQTFGRVTGVYGALVAWIIAGVGMLMLALV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHCCHHHHHHEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2158926; 10984043; 1311296 [H]