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The map label for this gene is degP [H]

Identifier: 116624862

GI number: 116624862

Start: 7249238

End: 7250716

Strand: Reverse

Name: degP [H]

Synonym: Acid_5786

Alternate gene names: 116624862

Gene position: 7250716-7249238 (Counterclockwise)

Preceding gene: 116624867

Following gene: 116624859

Centisome position: 72.76

GC content: 63.49

Gene sequence:

>1479_bases
ATGTCAACGCGAACTATGTTGATCGCTCCGGCCGTGGTGCTGGTCGCGCTTGCCGCCTGCGGCAGGCAAACCTCAAGCAG
CAGCAAGAATTCTGCGAATCGCGAGGAGACAAGCTCCTCCGCGATTGTCAGCAGGCCCGGCCCCCCGCTCTCCTATGCTG
ACGTCGTGGATCACGCCTCGCCCGCGGTAGTAACGATCCGCTCGGAACGCCGTGTGCGCGCTCCGGAGCAATTTCCGTTC
GCGGAAGATCCGTCGTTTCGCCAGTTCTTCGGCAACCCGTTGCCGGGGCGCGGCGGGCAATCCGCGCCCAGCCAGGTGGA
ACACGCCCTCGGCTCCGGGGTAATTGTTCGCGCTGACGGGCACATCCTGACAAACCATCACGTGGTCGATGGCGCCGAAG
ATATTAAAGTCGATCTCAACGACCACCGTACGTTGTCCGCGAAAGTGGTAGGCGTGGATCCGCCGAGCGATCTGGCGGTC
CTGAAGATCGACGCCCAGGATCTGCCCGTGCTGGCCCTGGCCGATTCCGATCGCGTGCGTGTCGGAGATATTTGCCTCGC
CGTCGGAAACCCCCTCGGCGTGGGGCAGACCGTCACCGCCGGCATCATCAGCGCCAGAAGCCGCAGCACGGATCTAAGTA
CGGGAAGTTTCGAAGACTTCCTGCAGACCGACGCCCCAATCAATCAGGGCAACTCGGGCGGAGCGCTGATCAATACCAAC
GCGGCGCTAATCGGCATCAACTCGCAGATTCTCTCGCCGACCGGAGGCAACATCGGAATCGGCTTCGCCATTCCGTCTAA
TCTGGCGAAGAACGTCATGGATCAGCTGATCACCACGGGCAAGGTCCACCGCGGCCAGCTCGGCGTAGGTGTGCAACCCC
TCACATCCGATCTCGCATCCGGCCTCGGCCTGAAGGAAGTTCGCGGTGTGCTGGTCAACCTGGTCAAGCCTGGAAGCCCC
GCGGACCGTGCAGGAATTCGCAATGGCGACGTGATCACGGCTATCGATGGACACCCTGTGGACGAACCCAACGCACTGAG
GAATCGAGTTGCCACCACCGCACCGGATTCCCAGGCGAAGCTCTCCTTTATTCGCGATGGCAAGGAACAGCAGGTAACGG
TCAAACTCGGCGAGCTGACGGCGGAATCGGCAGCGATGGAGCGGCCTAACGGCATGCCCGGCAACGCTCCCACCGATCGG
CGCCTCGGCGTAAGCGTTGAGCCCTTGTCTCCTGCCCTCGCGCAGGAGCTCGGCGTGCGCCGGGATATGCAGGGACTGGC
GGTGCGCGACGTCCAGCCCGATGGGCCGGCCGCGCGGGCCGGCGTGCAACCCGGCGACGTGATCATCGCGTTAAACCGGC
AGGCCGTGCGGTCCGCGGCCGATGTCGCGGCAGCGCTCAGGAGTGCGTCCTCCAGGCCGAGCCTGTTACTGATTAATCGA
GCCGGACAGAATGTGTTTCTAACCGTGAGTCCGCAGTAG

Upstream 100 bases:

>100_bases
TTCGGGGACTGCGCCCGAATCAGGCCGATTCATTTTTTGGGGTTCGCCGTCCAGGATTCAAATTATTAGATCGCTGCGAG
GCAGGCGACATCTCCTTAGT

Downstream 100 bases:

>100_bases
TTTGCACAAGACGCCGACAGTTTTAGCAAACGCTCCCTCACGGTCGCGGCTTCCATGAGAAGGCCCCCCTCTGTCAAGAA
AATAATCTACAAGGGCTGAG

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MSTRTMLIAPAVVLVALAACGRQTSSSSKNSANREETSSSAIVSRPGPPLSYADVVDHASPAVVTIRSERRVRAPEQFPF
AEDPSFRQFFGNPLPGRGGQSAPSQVEHALGSGVIVRADGHILTNHHVVDGAEDIKVDLNDHRTLSAKVVGVDPPSDLAV
LKIDAQDLPVLALADSDRVRVGDICLAVGNPLGVGQTVTAGIISARSRSTDLSTGSFEDFLQTDAPINQGNSGGALINTN
AALIGINSQILSPTGGNIGIGFAIPSNLAKNVMDQLITTGKVHRGQLGVGVQPLTSDLASGLGLKEVRGVLVNLVKPGSP
ADRAGIRNGDVITAIDGHPVDEPNALRNRVATTAPDSQAKLSFIRDGKEQQVTVKLGELTAESAAMERPNGMPGNAPTDR
RLGVSVEPLSPALAQELGVRRDMQGLAVRDVQPDGPAARAGVQPGDVIIALNRQAVRSAADVAAALRSASSRPSLLLINR
AGQNVFLTVSPQ

Sequences:

>Translated_492_residues
MSTRTMLIAPAVVLVALAACGRQTSSSSKNSANREETSSSAIVSRPGPPLSYADVVDHASPAVVTIRSERRVRAPEQFPF
AEDPSFRQFFGNPLPGRGGQSAPSQVEHALGSGVIVRADGHILTNHHVVDGAEDIKVDLNDHRTLSAKVVGVDPPSDLAV
LKIDAQDLPVLALADSDRVRVGDICLAVGNPLGVGQTVTAGIISARSRSTDLSTGSFEDFLQTDAPINQGNSGGALINTN
AALIGINSQILSPTGGNIGIGFAIPSNLAKNVMDQLITTGKVHRGQLGVGVQPLTSDLASGLGLKEVRGVLVNLVKPGSP
ADRAGIRNGDVITAIDGHPVDEPNALRNRVATTAPDSQAKLSFIRDGKEQQVTVKLGELTAESAAMERPNGMPGNAPTDR
RLGVSVEPLSPALAQELGVRRDMQGLAVRDVQPDGPAARAGVQPGDVIIALNRQAVRSAADVAAALRSASSRPSLLLINR
AGQNVFLTVSPQ
>Mature_491_residues
STRTMLIAPAVVLVALAACGRQTSSSSKNSANREETSSSAIVSRPGPPLSYADVVDHASPAVVTIRSERRVRAPEQFPFA
EDPSFRQFFGNPLPGRGGQSAPSQVEHALGSGVIVRADGHILTNHHVVDGAEDIKVDLNDHRTLSAKVVGVDPPSDLAVL
KIDAQDLPVLALADSDRVRVGDICLAVGNPLGVGQTVTAGIISARSRSTDLSTGSFEDFLQTDAPINQGNSGGALINTNA
ALIGINSQILSPTGGNIGIGFAIPSNLAKNVMDQLITTGKVHRGQLGVGVQPLTSDLASGLGLKEVRGVLVNLVKPGSPA
DRAGIRNGDVITAIDGHPVDEPNALRNRVATTAPDSQAKLSFIRDGKEQQVTVKLGELTAESAAMERPNGMPGNAPTDRR
LGVSVEPLSPALAQELGVRRDMQGLAVRDVQPDGPAARAGVQPGDVIIALNRQAVRSAADVAAALRSASSRPSLLLINRA
GQNVFLTVSPQ

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=306, Percent_Identity=35.2941176470588, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI22129776, Length=322, Percent_Identity=34.1614906832298, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI7019477, Length=353, Percent_Identity=33.4277620396601, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI24308541, Length=244, Percent_Identity=37.7049180327869, Blast_Score=126, Evalue=6e-29,
Organism=Escherichia coli, GI1789629, Length=463, Percent_Identity=40.1727861771058, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1786356, Length=481, Percent_Identity=40.956340956341, Blast_Score=301, Evalue=6e-83,
Organism=Escherichia coli, GI1789630, Length=385, Percent_Identity=36.8831168831169, Blast_Score=189, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24646839, Length=284, Percent_Identity=33.8028169014084, Blast_Score=128, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 51038; Mature: 50907

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRTMLIAPAVVLVALAACGRQTSSSSKNSANREETSSSAIVSRPGPPLSYADVVDHAS
CCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCEEEECCCCCCCHHHHHCCCC
PAVVTIRSERRVRAPEQFPFAEDPSFRQFFGNPLPGRGGQSAPSQVEHALGSGVIVRADG
CEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEECC
HILTNHHVVDGAEDIKVDLNDHRTLSAKVVGVDPPSDLAVLKIDAQDLPVLALADSDRVR
EEEECCEEECCCCEEEEECCCCEEEEEEEEECCCCCCEEEEEECCCCCCEEEECCCCCEE
VGDICLAVGNPLGVGQTVTAGIISARSRSTDLSTGSFEDFLQTDAPINQGNSGGALINTN
EEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEECC
AALIGINSQILSPTGGNIGIGFAIPSNLAKNVMDQLITTGKVHRGQLGVGVQPLTSDLAS
EEEEEECCEEECCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHC
GLGLKEVRGVLVNLVKPGSPADRAGIRNGDVITAIDGHPVDEPNALRNRVATTAPDSQAK
CCCHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCHHH
LSFIRDGKEQQVTVKLGELTAESAAMERPNGMPGNAPTDRRLGVSVEPLSPALAQELGVR
HHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHCCH
RDMQGLAVRDVQPDGPAARAGVQPGDVIIALNRQAVRSAADVAAALRSASSRPSLLLINR
HCCCCCEEEECCCCCCHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEE
AGQNVFLTVSPQ
CCCEEEEEECCC
>Mature Secondary Structure 
STRTMLIAPAVVLVALAACGRQTSSSSKNSANREETSSSAIVSRPGPPLSYADVVDHAS
CCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCEEEECCCCCCCHHHHHCCCC
PAVVTIRSERRVRAPEQFPFAEDPSFRQFFGNPLPGRGGQSAPSQVEHALGSGVIVRADG
CEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEECC
HILTNHHVVDGAEDIKVDLNDHRTLSAKVVGVDPPSDLAVLKIDAQDLPVLALADSDRVR
EEEECCEEECCCCEEEEECCCCEEEEEEEEECCCCCCEEEEEECCCCCCEEEECCCCCEE
VGDICLAVGNPLGVGQTVTAGIISARSRSTDLSTGSFEDFLQTDAPINQGNSGGALINTN
EEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEECC
AALIGINSQILSPTGGNIGIGFAIPSNLAKNVMDQLITTGKVHRGQLGVGVQPLTSDLAS
EEEEEECCEEECCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHC
GLGLKEVRGVLVNLVKPGSPADRAGIRNGDVITAIDGHPVDEPNALRNRVATTAPDSQAK
CCCHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCHHH
LSFIRDGKEQQVTVKLGELTAESAAMERPNGMPGNAPTDRRLGVSVEPLSPALAQELGVR
HHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHCCH
RDMQGLAVRDVQPDGPAARAGVQPGDVIIALNRQAVRSAADVAAALRSASSRPSLLLINR
HCCCCCEEEECCCCCCHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEE
AGQNVFLTVSPQ
CCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]