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The map label for this gene is lutB [H]

Identifier: 116624838

GI number: 116624838

Start: 7219724

End: 7221142

Strand: Reverse

Name: lutB [H]

Synonym: Acid_5762

Alternate gene names: 116624838

Gene position: 7221142-7219724 (Counterclockwise)

Preceding gene: 116624839

Following gene: 116624837

Centisome position: 72.46

GC content: 61.66

Gene sequence:

>1419_bases
ATGTCTGTCGAATTCGATCAGAAAATTCACACTACCCTGGCCGACGCCAATCTTCAGTTGGCCATCTACACCGCCACCGG
CCGGCTGAAAGAGAAGCGCATCGAAGCCGTAAGCGATGCCTGGCTGCCCGATTACCAGGAGCTTCGCACGCAGGCGAACG
CGATCAAGAAGCACGCGATCGAGAACCTCGACCATTACCTGGAAGAGTTCGAGCGCAATGTGGAAGCGCGCGGCGGCAAG
GTGATCTATTGCAAGGATGCCACCGAGGTTTCGGACTTCGTGCTGGCGCTCGCCAAGGAGCGTGGCTCCAGGCTGATCGT
GAAATCGAAATCGATGACCACCGAAGAGGTGGATCTCAACGAGCGCCTGGAGCATCACGGCCTGGAATCGGTGGAGACCG
ACCTGGGCGAATATATTCTGCAGCTGGCGCACGAGAAGCCCTATCATATCGTGGCCCCGGCGTTGCACAAAACGCGCTAC
GACGTGGCCGAGATCTTCACTCGCGAGCTCCACGTCGAAAATGAAACCGTCCCCGAGAAGCAGACGCTGATCGCGCGCGA
AGTGCTGCGCGAAAAATTCCTGCATGCCGATATCGGCATCAGCGGCGCCAATTTCCTGGTGGCCGATTCCGGCGCGGTCA
CAATCATTGAGAACGAAGGCAACGCGCGCCTCACCACCTCCGCTCCCAGGATCCACATCGCCGTAGCGGGAATCGAAAAG
GTGATCCCGCGCGCGCAGGATCTTGCAGTTTTCCTGAAGCTGCTGGCGCGCAGCGCGACCGGCCAGCTGCTTTCGGTCTA
CGCGTCCTTCCTGAGCGGCGCGAAGCGGCCGGGTGAAGTCGATGGGCCCGAGGAATTCTACGTGGTGCTGCTGGATAACG
GACGCACCAAGCTGCTCCCCGATCGTTCCAAGCGGCAGTCCTTGTACTGCATACGCTGCGGCGCCTGCCTCAACACGTGC
CCGGTGTATCGCAAGATCGGCGGCCACAGTTTCCCGTGGGTCTATTCGGGGCCGATCGGCGCCATCATCACACCGCAGTT
CATGGGCGTGTCGCATGAGCCGGGGCTCCCGTTTGCGTCGAGCCTCTGCGGCGCCTGCGGCGAGGTCTGTCCGGTCAAGA
TCGACATTCCGAAGGTGCTGCTGGAATTGCGCAGCGACGTGAAGAAGGCCGAGACTCGCGAAGGCCAGAACCGGATCGAG
AAGCTCGCCTTCCGCATCTTCGCCTGGGTCATGACGCATCCCCGGATTTACGAGCTCGCCGGACGCATGGCCGGCGGCAT
GGCGCCTTCGGGCGATGGCAAGTGGATCAACAGCGTGCCTGCGCCAATGAATGTCGGGCCGCTGAAGGCGTGGTTGAGCC
AGCGCGACCTGCCGCCCTCTCCCTCCAAGAGCTTCCGCGAAATGTGGAGGGCTCGCTGA

Upstream 100 bases:

>100_bases
CTCGACCCCAGCTGCCTCATGCAGATTCAGGGCGGGCTCTCCCGCGCGGGTTCCAGCGTGCGCACCATGCACCTGGCGGA
AGTTCTGGCGAGCCGCTAAC

Downstream 100 bases:

>100_bases
TGTCGCGCGATAACATCCTGCACAAGGTGCGCACCGCCCTGGGTCGCAGCGCCGGCCAGGCGGTAGCGCCTCCGCCCCCG
GTGCGGCTGCGTATTCCGGA

Product: iron-sulfur cluster binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSVEFDQKIHTTLADANLQLAIYTATGRLKEKRIEAVSDAWLPDYQELRTQANAIKKHAIENLDHYLEEFERNVEARGGK
VIYCKDATEVSDFVLALAKERGSRLIVKSKSMTTEEVDLNERLEHHGLESVETDLGEYILQLAHEKPYHIVAPALHKTRY
DVAEIFTRELHVENETVPEKQTLIAREVLREKFLHADIGISGANFLVADSGAVTIIENEGNARLTTSAPRIHIAVAGIEK
VIPRAQDLAVFLKLLARSATGQLLSVYASFLSGAKRPGEVDGPEEFYVVLLDNGRTKLLPDRSKRQSLYCIRCGACLNTC
PVYRKIGGHSFPWVYSGPIGAIITPQFMGVSHEPGLPFASSLCGACGEVCPVKIDIPKVLLELRSDVKKAETREGQNRIE
KLAFRIFAWVMTHPRIYELAGRMAGGMAPSGDGKWINSVPAPMNVGPLKAWLSQRDLPPSPSKSFREMWRAR

Sequences:

>Translated_472_residues
MSVEFDQKIHTTLADANLQLAIYTATGRLKEKRIEAVSDAWLPDYQELRTQANAIKKHAIENLDHYLEEFERNVEARGGK
VIYCKDATEVSDFVLALAKERGSRLIVKSKSMTTEEVDLNERLEHHGLESVETDLGEYILQLAHEKPYHIVAPALHKTRY
DVAEIFTRELHVENETVPEKQTLIAREVLREKFLHADIGISGANFLVADSGAVTIIENEGNARLTTSAPRIHIAVAGIEK
VIPRAQDLAVFLKLLARSATGQLLSVYASFLSGAKRPGEVDGPEEFYVVLLDNGRTKLLPDRSKRQSLYCIRCGACLNTC
PVYRKIGGHSFPWVYSGPIGAIITPQFMGVSHEPGLPFASSLCGACGEVCPVKIDIPKVLLELRSDVKKAETREGQNRIE
KLAFRIFAWVMTHPRIYELAGRMAGGMAPSGDGKWINSVPAPMNVGPLKAWLSQRDLPPSPSKSFREMWRAR
>Mature_471_residues
SVEFDQKIHTTLADANLQLAIYTATGRLKEKRIEAVSDAWLPDYQELRTQANAIKKHAIENLDHYLEEFERNVEARGGKV
IYCKDATEVSDFVLALAKERGSRLIVKSKSMTTEEVDLNERLEHHGLESVETDLGEYILQLAHEKPYHIVAPALHKTRYD
VAEIFTRELHVENETVPEKQTLIAREVLREKFLHADIGISGANFLVADSGAVTIIENEGNARLTTSAPRIHIAVAGIEKV
IPRAQDLAVFLKLLARSATGQLLSVYASFLSGAKRPGEVDGPEEFYVVLLDNGRTKLLPDRSKRQSLYCIRCGACLNTCP
VYRKIGGHSFPWVYSGPIGAIITPQFMGVSHEPGLPFASSLCGACGEVCPVKIDIPKVLLELRSDVKKAETREGQNRIEK
LAFRIFAWVMTHPRIYELAGRMAGGMAPSGDGKWINSVPAPMNVGPLKAWLSQRDLPPSPSKSFREMWRAR

Specific function: Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofi

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=470, Percent_Identity=40.2127659574468, Blast_Score=379, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 52547; Mature: 52416

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEFDQKIHTTLADANLQLAIYTATGRLKEKRIEAVSDAWLPDYQELRTQANAIKKHAI
CCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ENLDHYLEEFERNVEARGGKVIYCKDATEVSDFVLALAKERGSRLIVKSKSMTTEEVDLN
HHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHCCHH
ERLEHHGLESVETDLGEYILQLAHEKPYHIVAPALHKTRYDVAEIFTRELHVENETVPEK
HHHHHCCCHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHH
QTLIAREVLREKFLHADIGISGANFLVADSGAVTIIENEGNARLTTSAPRIHIAVAGIEK
HHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCEEEEECCCEEEEEEECHHH
VIPRAQDLAVFLKLLARSATGQLLSVYASFLSGAKRPGEVDGPEEFYVVLLDNGRTKLLP
HCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCC
DRSKRQSLYCIRCGACLNTCPVYRKIGGHSFPWVYSGPIGAIITPQFMGVSHEPGLPFAS
CCCCCCCEEEEECCCHHHHCHHHHHHCCCCCCEEECCCCCCEECHHHCCCCCCCCCCHHH
SLCGACGEVCPVKIDIPKVLLELRSDVKKAETREGQNRIEKLAFRIFAWVMTHPRIYELA
HHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GRMAGGMAPSGDGKWINSVPAPMNVGPLKAWLSQRDLPPSPSKSFREMWRAR
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
SVEFDQKIHTTLADANLQLAIYTATGRLKEKRIEAVSDAWLPDYQELRTQANAIKKHAI
CCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ENLDHYLEEFERNVEARGGKVIYCKDATEVSDFVLALAKERGSRLIVKSKSMTTEEVDLN
HHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHCCHH
ERLEHHGLESVETDLGEYILQLAHEKPYHIVAPALHKTRYDVAEIFTRELHVENETVPEK
HHHHHCCCHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHH
QTLIAREVLREKFLHADIGISGANFLVADSGAVTIIENEGNARLTTSAPRIHIAVAGIEK
HHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCEEEEECCCEEEEEEECHHH
VIPRAQDLAVFLKLLARSATGQLLSVYASFLSGAKRPGEVDGPEEFYVVLLDNGRTKLLP
HCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCC
DRSKRQSLYCIRCGACLNTCPVYRKIGGHSFPWVYSGPIGAIITPQFMGVSHEPGLPFAS
CCCCCCCEEEEECCCHHHHCHHHHHHCCCCCCEEECCCCCCEECHHHCCCCCCCCCCHHH
SLCGACGEVCPVKIDIPKVLLELRSDVKKAETREGQNRIEKLAFRIFAWVMTHPRIYELA
HHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GRMAGGMAPSGDGKWINSVPAPMNVGPLKAWLSQRDLPPSPSKSFREMWRAR
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]