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The map label for this gene is algU [H]

Identifier: 116624615

GI number: 116624615

Start: 6943570

End: 6944232

Strand: Direct

Name: algU [H]

Synonym: Acid_5539

Alternate gene names: 116624615

Gene position: 6943570-6944232 (Clockwise)

Preceding gene: 116624613

Following gene: 116624616

Centisome position: 69.68

GC content: 58.07

Gene sequence:

>663_bases
GTGGCCGCATCAATCTTCGAGTTGAGCCCGGATCGGACGGCGGGCAACGTGGAAGTCGAAGACTTCCGCTTGGTGGAATC
TCTGCGCGAAGGCTCCGAAAGAGCCTACGAGGAGCTCCTTACCCGCTTCCAGCAACCGGTGTACGCCCTCGCTTTGCGTC
TGTTAGACGATCAGGGTGAGGCTTGCGATGTTGTCCAGGAAGTCTTCCTGAAGGTCTTCCGCAATATCGGTAGCTTCCGC
GGTCAGAGCACTTTGAAAACGTGGATCTACCGGATCACGGTAAACGAGGCTCACAACGCGCGGCGCTGGTTTTTCCGGCA
CCGTCGCGCGGAAGTGGAACTCGATAAGGCTCCGGAGGACTCCCGGAATTTGAAGGAAGTGATTCCAGATCGCAGCCGGT
CTCCTTTCGACGAGGCGTTCAGCCGTGAACAGCACGTCATGATCGAGGCTGCGTTAGAGAGAATAAACCCGATTTTCCGC
GAAGCCGTAGTGTTGAGAGACATCACGGATCTTGCATATGAAGAAATCGCGGAAGTCCTCGGGGTTTCGCTGGGAACAGT
GAAGTCCCGTATCCTGCGAGGCCGGGAAGCCTTGCGGGAAGAGCTCGCGGGAAGCCTGAATGCAGGCCCGGCCCCGCGTT
TAGTGCCCACGACGGCAGAGTGA

Upstream 100 bases:

>100_bases
TCAGCGATCCGGGAACTTTTTCTCACAGCAGGTGTCTACTCCTTTGCAAGGGGCAGCATTTCCTGATAGCTTGAGATCAG
GCTAAATTGTGAGGCTTCCG

Downstream 100 bases:

>100_bases
TGCTATGAGCTGTGAAAACGTGCAAGAACGGATCTCCCTCCTGCTGGATTGCAAGCTTCCAGACAGTGACCGGGAGCATG
TGTTGGCGCACATCAATACG

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MAASIFELSPDRTAGNVEVEDFRLVESLREGSERAYEELLTRFQQPVYALALRLLDDQGEACDVVQEVFLKVFRNIGSFR
GQSTLKTWIYRITVNEAHNARRWFFRHRRAEVELDKAPEDSRNLKEVIPDRSRSPFDEAFSREQHVMIEAALERINPIFR
EAVVLRDITDLAYEEIAEVLGVSLGTVKSRILRGREALREELAGSLNAGPAPRLVPTTAE

Sequences:

>Translated_220_residues
MAASIFELSPDRTAGNVEVEDFRLVESLREGSERAYEELLTRFQQPVYALALRLLDDQGEACDVVQEVFLKVFRNIGSFR
GQSTLKTWIYRITVNEAHNARRWFFRHRRAEVELDKAPEDSRNLKEVIPDRSRSPFDEAFSREQHVMIEAALERINPIFR
EAVVLRDITDLAYEEIAEVLGVSLGTVKSRILRGREALREELAGSLNAGPAPRLVPTTAE
>Mature_219_residues
AASIFELSPDRTAGNVEVEDFRLVESLREGSERAYEELLTRFQQPVYALALRLLDDQGEACDVVQEVFLKVFRNIGSFRG
QSTLKTWIYRITVNEAHNARRWFFRHRRAEVELDKAPEDSRNLKEVIPDRSRSPFDEAFSREQHVMIEAALERINPIFRE
AVVLRDITDLAYEEIAEVLGVSLGTVKSRILRGREALREELAGSLNAGPAPRLVPTTAE

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=187, Percent_Identity=34.7593582887701, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 25143; Mature: 25012

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASIFELSPDRTAGNVEVEDFRLVESLREGSERAYEELLTRFQQPVYALALRLLDDQGE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ACDVVQEVFLKVFRNIGSFRGQSTLKTWIYRITVNEAHNARRWFFRHRRAEVELDKAPED
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCCCCCCC
SRNLKEVIPDRSRSPFDEAFSREQHVMIEAALERINPIFREAVVLRDITDLAYEEIAEVL
CHHHHHHCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVSLGTVKSRILRGREALREELAGSLNAGPAPRLVPTTAE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AASIFELSPDRTAGNVEVEDFRLVESLREGSERAYEELLTRFQQPVYALALRLLDDQGE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ACDVVQEVFLKVFRNIGSFRGQSTLKTWIYRITVNEAHNARRWFFRHRRAEVELDKAPED
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCCCCCCC
SRNLKEVIPDRSRSPFDEAFSREQHVMIEAALERINPIFREAVVLRDITDLAYEEIAEVL
CHHHHHHCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVSLGTVKSRILRGREALREELAGSLNAGPAPRLVPTTAE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8432708; 8378309; 7961421; 10984043; 7737518 [H]