Click here to switch to the map view.

The map label for this gene is aao [H]

Identifier: 116624522

GI number: 116624522

Start: 6824692

End: 6825825

Strand: Direct

Name: aao [H]

Synonym: Acid_5446

Alternate gene names: 116624522

Gene position: 6824692-6825825 (Clockwise)

Preceding gene: 116624518

Following gene: 116624523

Centisome position: 68.48

GC content: 66.93

Gene sequence:

>1134_bases
ATGACAGCACTCACCCGCCGCACCTTCCTGGGCGCTGCCCCTCTGACCCTGGCGGGTTGTGCGGCGCGCCGGGCCGCGCT
TCCGCCCGCGTCGCCAGCCGCTCGTCTGCCCCAGGTCTTCGTTTCCCCCGGGCGTGTCATCCGCACCACCGTCGGACTCC
GTCCTTTCCGGCCCGGCGGCTTCGTGGTTCGCGCGCAGAAGCTCGATTCCAAAACCGTGATTCACAATTACGGCCACGGC
GGCGCAGGCATTACGCTTTCCTGGGGCACCGCCCAGCTGGCGGCCGACGAAGCCCGCGCCGCTGGTTTGAAGACATCCGG
TCCCGGCGAGTGCGCCGTCATCGGCTGCGGGGTCATCGGCCTGGCCACCGCCCGACTCCTCCAGGAGCGCGGCTACTCCC
CAACCATCTACGCCCGCGAAATGCCCCCTAACACCACCTCCAACCTCGCCGGTGGATTGTGGGAGCCCGTCTCCCTCTTC
GATGAACCGCGCGTCACTCCGGAATTCCGCCGCCAGTTCAGCGAGGCAGCCCGCATCGCGTTCCGCCGCTACCAGTCCTT
CGCCGGCGAGCCCTACGGCGTCCGCTGGCTGCCCCTCTACAGCCTCAACCGCGAACACGCCTACGCCGCACCTTCGCCCG
AACGGCCGGACAGCGACATCGAGTCTCTGTATCCCGAGGCGCGCCCGCTCAGTCCCACCGAAAACCCATTCGACGTCCCG
TACGCCTACCGCCGCCAGACCATGCTGATCGAGCCCGCCATCTACCTGAGCGCCCTGATCCGCGATTTCCACTCCGCCGG
CGGTAAGATCGTCATCCGCGACTTCCCCTCGACTTCCGCCCTGATGGAACTACGCGAGCCGCTCTTGTTCAATTGCACCG
GACTCGGCGCCCGCGCGCTCTTCGGGGATGAGGACCTGATTCCCATCCGCGGGCAGCTGGTCGTCCTCCTGCCCCAACCC
GAGCTGAATTACTGCACCATCGGACCTTCGGGAGTCTATATGTTCCCCCGGCACGACGGCGTCCTGCTCGGCGGCAGCTT
CGAGCGCGGCGTCTGGAACACCGACCCGGACCCCACGGTCACGGAGCGCATTTTACGCGATAACAGCTTACTTTTCGGAG
CTATGCGGCGTTAA

Upstream 100 bases:

>100_bases
CGCGACCGGCCGGGGCGGCCCGGCGCCAACATTGGATTTTTTCCTGGACAGACTTGTCGCTCCGGTAATTTTGCGGGCTG
ATAAGGCTAAACTTCATTGT

Downstream 100 bases:

>100_bases
CGGAATTAGGGATATGGAACTACGCTCCCGTACCCTTACTAACAAAAGATAGCGTTGCCATTCAGGGCATCCGCCGCAAA
ACTTGAACCTATGACGAATA

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: DAAO; DAMOX; DAO [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MTALTRRTFLGAAPLTLAGCAARRAALPPASPAARLPQVFVSPGRVIRTTVGLRPFRPGGFVVRAQKLDSKTVIHNYGHG
GAGITLSWGTAQLAADEARAAGLKTSGPGECAVIGCGVIGLATARLLQERGYSPTIYAREMPPNTTSNLAGGLWEPVSLF
DEPRVTPEFRRQFSEAARIAFRRYQSFAGEPYGVRWLPLYSLNREHAYAAPSPERPDSDIESLYPEARPLSPTENPFDVP
YAYRRQTMLIEPAIYLSALIRDFHSAGGKIVIRDFPSTSALMELREPLLFNCTGLGARALFGDEDLIPIRGQLVVLLPQP
ELNYCTIGPSGVYMFPRHDGVLLGGSFERGVWNTDPDPTVTERILRDNSLLFGAMRR

Sequences:

>Translated_377_residues
MTALTRRTFLGAAPLTLAGCAARRAALPPASPAARLPQVFVSPGRVIRTTVGLRPFRPGGFVVRAQKLDSKTVIHNYGHG
GAGITLSWGTAQLAADEARAAGLKTSGPGECAVIGCGVIGLATARLLQERGYSPTIYAREMPPNTTSNLAGGLWEPVSLF
DEPRVTPEFRRQFSEAARIAFRRYQSFAGEPYGVRWLPLYSLNREHAYAAPSPERPDSDIESLYPEARPLSPTENPFDVP
YAYRRQTMLIEPAIYLSALIRDFHSAGGKIVIRDFPSTSALMELREPLLFNCTGLGARALFGDEDLIPIRGQLVVLLPQP
ELNYCTIGPSGVYMFPRHDGVLLGGSFERGVWNTDPDPTVTERILRDNSLLFGAMRR
>Mature_376_residues
TALTRRTFLGAAPLTLAGCAARRAALPPASPAARLPQVFVSPGRVIRTTVGLRPFRPGGFVVRAQKLDSKTVIHNYGHGG
AGITLSWGTAQLAADEARAAGLKTSGPGECAVIGCGVIGLATARLLQERGYSPTIYAREMPPNTTSNLAGGLWEPVSLFD
EPRVTPEFRRQFSEAARIAFRRYQSFAGEPYGVRWLPLYSLNREHAYAAPSPERPDSDIESLYPEARPLSPTENPFDVPY
AYRRQTMLIEPAIYLSALIRDFHSAGGKIVIRDFPSTSALMELREPLLFNCTGLGARALFGDEDLIPIRGQLVVLLPQPE
LNYCTIGPSGVYMFPRHDGVLLGGSFERGVWNTDPDPTVTERILRDNSLLFGAMRR

Specific function: Unknown

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DAMOX/DASOX family [H]

Homologues:

Organism=Homo sapiens, GI40217815, Length=263, Percent_Identity=28.8973384030418, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI148539837, Length=273, Percent_Identity=29.3040293040293, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24652525, Length=250, Percent_Identity=29.6, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023209
- InterPro:   IPR006076
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.3.3 [H]

Molecular weight: Translated: 41196; Mature: 41064

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00677 DAO

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALTRRTFLGAAPLTLAGCAARRAALPPASPAARLPQVFVSPGRVIRTTVGLRPFRPGG
CCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCHHHCCHHHCCCCCEEEEECCCCCCCCCC
FVVRAQKLDSKTVIHNYGHGGAGITLSWGTAQLAADEARAAGLKTSGPGECAVIGCGVIG
EEEEEECCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEECCHHH
LATARLLQERGYSPTIYAREMPPNTTSNLAGGLWEPVSLFDEPRVTPEFRRQFSEAARIA
HHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHH
FRRYQSFAGEPYGVRWLPLYSLNREHAYAAPSPERPDSDIESLYPEARPLSPTENPFDVP
HHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCC
YAYRRQTMLIEPAIYLSALIRDFHSAGGKIVIRDFPSTSALMELREPLLFNCTGLGARAL
HHHCCCEEEECHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCEEEECCCCCEEE
FGDEDLIPIRGQLVVLLPQPELNYCTIGPSGVYMFPRHDGVLLGGSFERGVWNTDPDPTV
ECCCCEEEECCCEEEEECCCCCCEEEECCCCEEEEECCCCEEECCCCCCCCCCCCCCHHH
TERILRDNSLLFGAMRR
HHHHHHCCCEEEEECCC
>Mature Secondary Structure 
TALTRRTFLGAAPLTLAGCAARRAALPPASPAARLPQVFVSPGRVIRTTVGLRPFRPGG
CCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCHHHCCHHHCCCCCEEEEECCCCCCCCCC
FVVRAQKLDSKTVIHNYGHGGAGITLSWGTAQLAADEARAAGLKTSGPGECAVIGCGVIG
EEEEEECCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEECCHHH
LATARLLQERGYSPTIYAREMPPNTTSNLAGGLWEPVSLFDEPRVTPEFRRQFSEAARIA
HHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHH
FRRYQSFAGEPYGVRWLPLYSLNREHAYAAPSPERPDSDIESLYPEARPLSPTENPFDVP
HHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCC
YAYRRQTMLIEPAIYLSALIRDFHSAGGKIVIRDFPSTSALMELREPLLFNCTGLGARAL
HHHCCCEEEECHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCEEEECCCCCEEE
FGDEDLIPIRGQLVVLLPQPELNYCTIGPSGVYMFPRHDGVLLGGSFERGVWNTDPDPTV
ECCCCEEEECCCEEEEECCCCCCEEEECCCCEEEEECCCCEEECCCCCCCCCCCCCCHHH
TERILRDNSLLFGAMRR
HHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]